CA2485662A1 - Modified polymeric films - Google Patents
Modified polymeric films Download PDFInfo
- Publication number
- CA2485662A1 CA2485662A1 CA002485662A CA2485662A CA2485662A1 CA 2485662 A1 CA2485662 A1 CA 2485662A1 CA 002485662 A CA002485662 A CA 002485662A CA 2485662 A CA2485662 A CA 2485662A CA 2485662 A1 CA2485662 A1 CA 2485662A1
- Authority
- CA
- Canada
- Prior art keywords
- film
- acid
- plasticiser
- film according
- hpmc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims abstract description 37
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract description 37
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims abstract description 34
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims abstract description 34
- 239000004014 plasticizer Substances 0.000 claims abstract description 21
- 239000002775 capsule Substances 0.000 claims abstract description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- 150000003839 salts Chemical class 0.000 claims abstract description 12
- 150000007524 organic acids Chemical class 0.000 claims abstract description 6
- 239000002253 acid Substances 0.000 claims description 22
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims description 12
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 9
- 150000007513 acids Chemical class 0.000 claims description 8
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims description 8
- 150000001298 alcohols Chemical class 0.000 claims description 7
- 150000001735 carboxylic acids Chemical group 0.000 claims description 7
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 7
- 239000001361 adipic acid Substances 0.000 claims description 4
- 235000011037 adipic acid Nutrition 0.000 claims description 4
- 235000019445 benzyl alcohol Nutrition 0.000 claims description 4
- 239000001530 fumaric acid Substances 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 3
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 3
- 239000011976 maleic acid Substances 0.000 claims 3
- 239000000463 material Substances 0.000 abstract description 11
- -1 hydroxypropyl methyl Chemical group 0.000 abstract description 3
- 239000000825 pharmaceutical preparation Substances 0.000 abstract description 3
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 239000010408 film Substances 0.000 description 64
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 239000000243 solution Substances 0.000 description 5
- 239000002202 Polyethylene glycol Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 4
- 150000001261 hydroxy acids Chemical class 0.000 description 4
- 229920001223 polyethylene glycol Polymers 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 229920006395 saturated elastomer Polymers 0.000 description 3
- YEJRWHAVMIAJKC-UHFFFAOYSA-N 4-Butyrolactone Chemical compound O=C1CCCO1 YEJRWHAVMIAJKC-UHFFFAOYSA-N 0.000 description 2
- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 235000015872 dietary supplement Nutrition 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- GAEKPEKOJKCEMS-UHFFFAOYSA-N gamma-valerolactone Chemical compound CC1CCC(=O)O1 GAEKPEKOJKCEMS-UHFFFAOYSA-N 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- QBYIENPQHBMVBV-HFEGYEGKSA-N (2R)-2-hydroxy-2-phenylacetic acid Chemical compound O[C@@H](C(O)=O)c1ccccc1.O[C@@H](C(O)=O)c1ccccc1 QBYIENPQHBMVBV-HFEGYEGKSA-N 0.000 description 1
- AFENDNXGAFYKQO-UHFFFAOYSA-N 2-hydroxybutyric acid Chemical compound CCC(O)C(O)=O AFENDNXGAFYKQO-UHFFFAOYSA-N 0.000 description 1
- SHHAJSKIXCFAER-UHFFFAOYSA-N C(CCC)O.C(C)(C)O.C(CC)O.C(C)O Chemical compound C(CCC)O.C(C)(C)O.C(CC)O.C(C)O SHHAJSKIXCFAER-UHFFFAOYSA-N 0.000 description 1
- LCBOXNMVVRSWTI-UHFFFAOYSA-N C(CCCCC)(=O)O.C(CCCC)(=O)O.C(CCC)(=O)O.C(CC)(=O)O.C(C)(=O)O Chemical compound C(CCCCC)(=O)O.C(CCCC)(=O)O.C(CCC)(=O)O.C(CC)(=O)O.C(C)(=O)O LCBOXNMVVRSWTI-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Chemical compound CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 1
- IWYDHOAUDWTVEP-UHFFFAOYSA-N R-2-phenyl-2-hydroxyacetic acid Natural products OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 description 1
- 150000001242 acetic acid derivatives Chemical class 0.000 description 1
- 239000008122 artificial sweetener Substances 0.000 description 1
- 235000021311 artificial sweeteners Nutrition 0.000 description 1
- 150000001277 beta hydroxy acids Chemical class 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000000989 food dye Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 229940093915 gynecological organic acid Drugs 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 229960002510 mandelic acid Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
- C08J5/18—Manufacture of films or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/09—Carboxylic acids; Metal salts thereof; Anhydrides thereof
- C08K5/092—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
- C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
- C08J2301/08—Cellulose derivatives
- C08J2301/26—Cellulose ethers
- C08J2301/28—Alkyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials Engineering (AREA)
- Medicinal Preparation (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0210859.5 | 2002-05-13 | ||
| GBGB0210859.5A GB0210859D0 (en) | 2002-05-13 | 2002-05-13 | Modified polymeric films |
| PCT/GB2003/001996 WO2003095548A1 (en) | 2002-05-13 | 2003-05-12 | Modified polymeric films |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2485662A1 true CA2485662A1 (en) | 2003-11-20 |
Family
ID=9936526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002485662A Abandoned CA2485662A1 (en) | 2002-05-13 | 2003-05-12 | Modified polymeric films |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050163824A1 (enExample) |
| EP (1) | EP1504055A1 (enExample) |
| JP (1) | JP2005525446A (enExample) |
| CN (1) | CN1653127A (enExample) |
| AU (1) | AU2003233890A1 (enExample) |
| CA (1) | CA2485662A1 (enExample) |
| GB (1) | GB0210859D0 (enExample) |
| NZ (1) | NZ536519A (enExample) |
| WO (1) | WO2003095548A1 (enExample) |
| ZA (1) | ZA200409175B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0221986D0 (en) * | 2002-09-21 | 2002-10-30 | Bioprogress Technology Ltd | Films with improved barrier properties |
| EP1811980B1 (en) * | 2004-09-30 | 2011-06-01 | The Hershey Company | Sealed, edible film strip packets and methods of making and using them |
| US20070231441A1 (en) * | 2006-03-29 | 2007-10-04 | Monosol, Llc | Edible film having improved sealing properties |
| US20080014228A1 (en) * | 2006-07-14 | 2008-01-17 | Olivia Darmuzey | Solid form |
| US20080311162A1 (en) * | 2007-05-16 | 2008-12-18 | Olivia Darmuzey | Solid form |
| TWI352717B (en) | 2007-12-11 | 2011-11-21 | Ind Tech Res Inst | A tenacity adjuster, a biodegradable material comp |
| JP5470032B2 (ja) | 2009-08-12 | 2014-04-16 | 富士フイルム株式会社 | セルロース誘導体、熱成形材料、成形体及びその製造方法並びに電気電子機器用筐体 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1969482A (en) * | 1932-12-23 | 1934-08-07 | Eastman Kodak Co | Cellulose organic ester composition containing an ester of maleic acid |
| US2835603A (en) * | 1953-11-25 | 1958-05-20 | Dow Chemical Co | Water-soluble thermoplastic cellulose ether compositions |
| GB1144225A (en) * | 1965-09-07 | 1969-03-05 | Dow Chemical Co | Preparation of medicinal capsule shells from hydroxyalkyl-alkyl cellulose ethers |
| US3903301A (en) * | 1973-02-28 | 1975-09-02 | Merck & Co Inc | Methods of treating muscular disorders |
| DE3233764C2 (de) * | 1982-09-11 | 1987-05-07 | R.P. Scherer GmbH, 6930 Eberbach | Verfahren zur Herstellung oraler Dosierungseinheiten |
| US4576646A (en) * | 1983-07-06 | 1986-03-18 | Seppic | Film-forming compositions for enveloping solid forms, particularly pharmaceutical or food products or seeds, and products obtained, coated with said compositions |
| CA2069495C (en) * | 1989-12-21 | 2006-05-09 | George Douglas Vaughn | Catalytic, water-soluble polymeric films for metal coatings |
| ATE192335T1 (de) * | 1990-12-20 | 2000-05-15 | Warner Jenkinson Co Inc | Filmbildende zusammensetzungen aus feuchtem pulver |
| FR2684874B1 (fr) * | 1991-12-13 | 1994-07-01 | Oreal | Systeme aerosol pour laque capillaire. |
| US5741533A (en) * | 1995-12-22 | 1998-04-21 | W. R. Grace & Co.-Conn. | Method of cooking a food product and product thereof |
| WO1998006385A1 (de) * | 1996-08-15 | 1998-02-19 | Losan Pharma Gmbh | Gut schluckbare orale arzneiform |
| MXPA02004981A (es) * | 1999-11-17 | 2004-11-12 | Reckitt Benckiser Uk Ltd | Capsula soluble en agua moldeada por inyeccion. |
| GB2374874A (en) * | 2001-04-11 | 2002-10-30 | Bioprogress Tech Int Inc | Modified cellulose films |
-
2002
- 2002-05-13 GB GBGB0210859.5A patent/GB0210859D0/en not_active Ceased
-
2003
- 2003-05-12 JP JP2004503554A patent/JP2005525446A/ja active Pending
- 2003-05-12 NZ NZ536519A patent/NZ536519A/en unknown
- 2003-05-12 AU AU2003233890A patent/AU2003233890A1/en not_active Abandoned
- 2003-05-12 WO PCT/GB2003/001996 patent/WO2003095548A1/en not_active Ceased
- 2003-05-12 CN CNA038107201A patent/CN1653127A/zh active Pending
- 2003-05-12 CA CA002485662A patent/CA2485662A1/en not_active Abandoned
- 2003-05-12 US US10/514,514 patent/US20050163824A1/en not_active Abandoned
- 2003-05-12 EP EP03727652A patent/EP1504055A1/en not_active Withdrawn
-
2004
- 2004-11-11 ZA ZA200409175A patent/ZA200409175B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ536519A (en) | 2006-10-27 |
| EP1504055A1 (en) | 2005-02-09 |
| CN1653127A (zh) | 2005-08-10 |
| ZA200409175B (en) | 2006-04-26 |
| GB0210859D0 (en) | 2002-06-19 |
| US20050163824A1 (en) | 2005-07-28 |
| WO2003095548A1 (en) | 2003-11-20 |
| AU2003233890A1 (en) | 2003-11-11 |
| JP2005525446A (ja) | 2005-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |