CA2482591A1 - Combination therapy for the treatment of cancer - Google Patents
Combination therapy for the treatment of cancer Download PDFInfo
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- CA2482591A1 CA2482591A1 CA002482591A CA2482591A CA2482591A1 CA 2482591 A1 CA2482591 A1 CA 2482591A1 CA 002482591 A CA002482591 A CA 002482591A CA 2482591 A CA2482591 A CA 2482591A CA 2482591 A1 CA2482591 A1 CA 2482591A1
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- pharmaceutically acceptable
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- human
- effective amount
- cancer
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0208680.9 | 2002-04-16 | ||
| GB0208680A GB0208680D0 (en) | 2002-04-16 | 2002-04-16 | Combination therapy |
| GB0218388A GB0218388D0 (en) | 2002-08-08 | 2002-08-08 | Combination therapy |
| GB0218388.7 | 2002-08-08 | ||
| PCT/GB2003/001617 WO2003088971A1 (en) | 2002-04-16 | 2003-04-14 | Combination therapy for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2482591A1 true CA2482591A1 (en) | 2003-10-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002482591A Abandoned CA2482591A1 (en) | 2002-04-16 | 2003-04-14 | Combination therapy for the treatment of cancer |
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| Country | Link |
|---|---|
| US (1) | US20050215530A1 (enExample) |
| EP (1) | EP1496909B1 (enExample) |
| JP (1) | JP2005530735A (enExample) |
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| CN (1) | CN100352441C (enExample) |
| AT (1) | ATE353650T1 (enExample) |
| AU (1) | AU2003216558B2 (enExample) |
| BR (1) | BR0309226A (enExample) |
| CA (1) | CA2482591A1 (enExample) |
| DE (1) | DE60311788T2 (enExample) |
| ES (1) | ES2280735T3 (enExample) |
| IL (1) | IL164564A0 (enExample) |
| MX (1) | MXPA04010166A (enExample) |
| NO (1) | NO20044498L (enExample) |
| NZ (1) | NZ535739A (enExample) |
| WO (1) | WO2003088971A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0218526D0 (en) * | 2002-08-09 | 2002-09-18 | Astrazeneca Ab | Combination therapy |
| JP2006527753A (ja) * | 2003-06-18 | 2006-12-07 | アンギオジェン・ファーマシューティカルズ・リミテッド | 結腸直腸癌などの治療のための、血管損傷効果を有する、５−ｆｕ、ｃｐｔ−１１または５−ｆｕおよびｃｐｔ−１１と組み合わせたｚｄ６１２６を含んでなる組成物 |
| ES2372694T3 (es) * | 2003-10-15 | 2012-01-25 | OSI Pharmaceuticals, LLC | Inhibidores de tirosina cinasa de imidazo[1,5-a]pirazina. |
| PT1740591E (pt) * | 2004-04-02 | 2009-09-24 | Osi Pharm Inc | Inibidores da proteína quinase heterobicíclicos em substituição de anel bicíclico 6,6 |
| JP2008501654A (ja) | 2004-06-03 | 2008-01-24 | エフ．ホフマン−ラ ロシュ アーゲー | シスプラチンとｅｇｆｒ阻害剤を用いた治療 |
| NZ551622A (en) * | 2004-06-03 | 2010-01-29 | Smithkline Beecham Cork Ltd | Treatment of esophageal cancer with lapatinib tosylate |
| US20060084666A1 (en) * | 2004-10-18 | 2006-04-20 | Harari Paul M | Combined treatment with radiation and an epidermal growth factor receptor kinase inhibitor |
| FR2886151B1 (fr) * | 2005-05-31 | 2007-09-07 | Mayoly Spindler Soc Par Action | Utilisation de la colchicine pour la preparation d'un medicament destine a la prevention et/ou au traitement de l'endometriose |
| US8575164B2 (en) * | 2005-12-19 | 2013-11-05 | OSI Pharmaceuticals, LLC | Combination cancer therapy |
| JP2011510018A (ja) * | 2008-01-18 | 2011-03-31 | オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド | 癌治療のためのイミダゾピラジノール誘導体 |
| ES2396613T3 (es) * | 2008-05-19 | 2013-02-22 | OSI Pharmaceuticals, LLC | Imidazopirazinas e imidazotriazinas sustituidas |
| JP2012520893A (ja) | 2009-03-18 | 2012-09-10 | オーエスアイ・ファーマシューティカルズ，エルエルシー | Ｅｇｆｒ阻害薬及びｉｇｆ−１ｒ阻害剤の投与を含む組み合わせ癌治療 |
| BRPI1016245A2 (pt) | 2009-04-20 | 2015-09-01 | Osi Pharmaceuticals Llc | Preparação de c-pirazina-metilaminas. |
| WO2010129740A1 (en) * | 2009-05-07 | 2010-11-11 | Osi Pharmaceuticals, Inc. | Use of osi-906 for treating adrenocortical carcinoma |
| WO2012129145A1 (en) | 2011-03-18 | 2012-09-27 | OSI Pharmaceuticals, LLC | Nscle combination therapy |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| GB9300059D0 (en) * | 1992-01-20 | 1993-03-03 | Zeneca Ltd | Quinazoline derivatives |
| GB9508538D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| GB9714249D0 (en) * | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| EE200200565A (et) * | 2000-03-31 | 2004-06-15 | Angiogene Pharmaceuticals Ltd. | Vaskulaarse kahjustava toimega kombinatsioonravi |
| GB0008269D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
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2003
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- 2003-04-14 CA CA002482591A patent/CA2482591A1/en not_active Abandoned
- 2003-04-14 JP JP2003585723A patent/JP2005530735A/ja active Pending
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- 2003-04-14 ES ES03712464T patent/ES2280735T3/es not_active Expired - Lifetime
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- 2003-04-14 EP EP03712464A patent/EP1496909B1/en not_active Expired - Lifetime
- 2003-04-14 KR KR10-2004-7016666A patent/KR20040103964A/ko not_active Ceased
- 2003-04-14 MX MXPA04010166A patent/MXPA04010166A/es active IP Right Grant
- 2003-04-14 DE DE60311788T patent/DE60311788T2/de not_active Expired - Fee Related
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- 2003-04-14 BR BR0309226-7A patent/BR0309226A/pt not_active IP Right Cessation
- 2003-04-14 CN CNB03813702XA patent/CN100352441C/zh not_active Expired - Fee Related
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2004
- 2004-10-13 IL IL16456404A patent/IL164564A0/xx unknown
- 2004-10-21 NO NO20044498A patent/NO20044498L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ535739A (en) | 2008-01-31 |
| EP1496909B1 (en) | 2007-02-14 |
| AU2003216558B2 (en) | 2008-05-29 |
| DE60311788D1 (de) | 2007-03-29 |
| WO2003088971A1 (en) | 2003-10-30 |
| BR0309226A (pt) | 2005-02-09 |
| ES2280735T3 (es) | 2007-09-16 |
| CN1658880A (zh) | 2005-08-24 |
| US20050215530A1 (en) | 2005-09-29 |
| CN100352441C (zh) | 2007-12-05 |
| ATE353650T1 (de) | 2007-03-15 |
| NO20044498L (no) | 2004-11-04 |
| EP1496909A1 (en) | 2005-01-19 |
| KR20040103964A (ko) | 2004-12-09 |
| DE60311788T2 (de) | 2007-11-22 |
| HK1071310A1 (en) | 2005-07-15 |
| MXPA04010166A (es) | 2005-02-03 |
| AU2003216558A1 (en) | 2003-11-03 |
| IL164564A0 (en) | 2005-12-18 |
| JP2005530735A (ja) | 2005-10-13 |
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