CA2477191A1 - Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines - Google Patents
Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines Download PDFInfo
- Publication number
- CA2477191A1 CA2477191A1 CA002477191A CA2477191A CA2477191A1 CA 2477191 A1 CA2477191 A1 CA 2477191A1 CA 002477191 A CA002477191 A CA 002477191A CA 2477191 A CA2477191 A CA 2477191A CA 2477191 A1 CA2477191 A1 CA 2477191A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- saponin
- group
- antigen
- aliphatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
L'invention concerne des compositions pharmaceutiques, en particulier des compositions de vaccins, qui renferment un systme adjuvant contenant au moins un compos~ de phosphate d'aminoalkyl glucosaminide et au moins un compos~ de saponine. Ces compositions favorisent de fa×on synerg~tique la r~ponse immunitaire d'un mammifre ~ un antigne administr~ conjointement. Par ailleurs, l'invention concerne des proc~d~s d'utilisation de ces compositions dans le traitement de diverses maladies humaines, y compris le cancer, ainsi que des infections microbiennes et des maladies auto-immunes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2002/003313 WO2003069997A1 (fr) | 2002-02-04 | 2002-02-04 | Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2477191A1 true CA2477191A1 (fr) | 2003-08-28 |
Family
ID=27752544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002477191A Abandoned CA2477191A1 (fr) | 2002-02-04 | 2002-02-04 | Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1476018A4 (fr) |
JP (1) | JP2005525344A (fr) |
AU (1) | AU2002240250A1 (fr) |
CA (1) | CA2477191A1 (fr) |
WO (1) | WO2003069997A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2651764A1 (fr) * | 2006-05-09 | 2007-11-22 | Gerald V. Quinnan | Compositions immunogenes anti-vih-1 |
EA201000829A1 (ru) * | 2007-12-21 | 2011-06-30 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина |
CN110833555B (zh) * | 2018-08-15 | 2023-03-24 | 广西梧州制药(集团)股份有限公司 | 吡唑并嘧啶衍生物在治疗溃疡性结肠炎的用途 |
AU2019411278A1 (en) * | 2018-12-21 | 2021-08-12 | Sapreme Technologies B.V. | Saponin conjugates |
CN110317794A (zh) * | 2019-06-12 | 2019-10-11 | 吉林特研生物技术有限责任公司 | 一种重组杆状病毒、貉细小病毒重组亚单位疫苗及其制备方法 |
KR20230043113A (ko) * | 2020-06-24 | 2023-03-30 | 사프렘 테크놀로지스 비.브이. | 의약용 사포닌 유도체 |
WO2024065107A1 (fr) * | 2022-09-26 | 2024-04-04 | Powin Biomedical Co., Ltd. | Nouvelles compositions comprenant un terpénoïde et une macromolécule et utilisations associées |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2235330T3 (es) * | 1997-05-20 | 2005-07-01 | Galenica Pharmaceuticals, Inc. | Analogos de saponionas triterpenicas que tienen actividad ayuvante. |
EP1265840A2 (fr) * | 2000-03-17 | 2002-12-18 | Corixa Corporation | Nouveaux aldehydes amphipathiques et leur utilisation en tant qu'adjuvants et effecteurs immunologiques |
WO2002003961A1 (fr) * | 2000-07-07 | 2002-01-17 | Corixa Corporation | Microspheres et adjuvants utilises pour l'administration de vaccins a base d'adn |
-
2002
- 2002-02-04 CA CA002477191A patent/CA2477191A1/fr not_active Abandoned
- 2002-02-04 EP EP02706143A patent/EP1476018A4/fr not_active Withdrawn
- 2002-02-04 AU AU2002240250A patent/AU2002240250A1/en not_active Abandoned
- 2002-02-04 WO PCT/US2002/003313 patent/WO2003069997A1/fr not_active Application Discontinuation
- 2002-02-04 JP JP2003568973A patent/JP2005525344A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1476018A4 (fr) | 2005-09-21 |
JP2005525344A (ja) | 2005-08-25 |
WO2003069997A1 (fr) | 2003-08-28 |
EP1476018A1 (fr) | 2004-11-17 |
AU2002240250A1 (en) | 2003-09-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6649172B2 (en) | Amphipathic aldehydes and their uses as adjuvants and immunoeffectors | |
US20030190333A1 (en) | Immunostimulant compositions comprising aminoalkyl glucosaminide phosphates and saponins | |
US6525028B1 (en) | Immunoeffector compounds | |
EP1311522B1 (fr) | Nouveaux composes immuno-effecteurs | |
AU2001281001A1 (en) | New immunoeffector compounds | |
EP1482795B1 (fr) | Nouveaux composes immuno-effecteurs | |
CA2477191A1 (fr) | Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines | |
US11912736B2 (en) | Diaryl trehalose compounds and uses thereof | |
US20030228279A1 (en) | Compositions and methods for viral delivery | |
RU2289585C2 (ru) | Новые аминоалкилглюкозаминидфосфатные соединения, иммуностимулирующая фармацевтическая композиция, их содержащая, и способ индуцирования иммунного ответа | |
NZ534478A (en) | New immunoeffector compounds | |
KR101070235B1 (ko) | 전호 추출물을 포함하는 면역보조제 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |