CA2475395C - Anti-human tenascin monoclonal antibody - Google Patents
Anti-human tenascin monoclonal antibody Download PDFInfo
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- CA2475395C CA2475395C CA2475395A CA2475395A CA2475395C CA 2475395 C CA2475395 C CA 2475395C CA 2475395 A CA2475395 A CA 2475395A CA 2475395 A CA2475395 A CA 2475395A CA 2475395 C CA2475395 C CA 2475395C
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- Prior art keywords
- antibody
- fragment
- tenascin
- seq
- ser
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
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- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US35929902P | 2002-02-26 | 2002-02-26 | |
| US60/359,299 | 2002-02-26 | ||
| PCT/IT2003/000098 WO2003072608A1 (en) | 2002-02-26 | 2003-02-20 | Anti-human tenascin monoclonal antibody |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2475395A1 CA2475395A1 (en) | 2003-09-04 |
| CA2475395C true CA2475395C (en) | 2011-08-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2475395A Expired - Fee Related CA2475395C (en) | 2002-02-26 | 2003-02-20 | Anti-human tenascin monoclonal antibody |
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| EP (1) | EP1478667B1 (enExample) |
| JP (1) | JP4488746B2 (enExample) |
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| CN (1) | CN1317303C (enExample) |
| AR (1) | AR038700A1 (enExample) |
| AT (1) | ATE480564T1 (enExample) |
| AU (1) | AU2003215900B2 (enExample) |
| BR (1) | BR0307994A (enExample) |
| CA (1) | CA2475395C (enExample) |
| CY (1) | CY1111108T1 (enExample) |
| DE (1) | DE60334076D1 (enExample) |
| DK (1) | DK1478667T3 (enExample) |
| ES (1) | ES2352180T3 (enExample) |
| MX (1) | MXPA04008216A (enExample) |
| PL (1) | PL213216B1 (enExample) |
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| SI (1) | SI1478667T1 (enExample) |
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| ITRM20040105A1 (it) * | 2004-02-27 | 2004-05-27 | Tecnogen Scpa | Anticorpo monoclonale antitenascina umana. |
| WO2008019326A2 (en) * | 2006-08-04 | 2008-02-14 | Novartis Ag | Ephb3-specific antibody and uses thereof |
| EP2235536A4 (en) | 2007-12-20 | 2011-05-04 | Lab Corp America Holdings | HER-2-DIAGNOSTIC PROCEDURE |
| FR2930036B1 (fr) * | 2008-04-11 | 2010-05-07 | Assist Publ Hopitaux De Paris | Procede de diagnostic d'une hypertension arterielle pulmonaire. |
| EP2313435A4 (en) * | 2008-07-01 | 2012-08-08 | Aveo Pharmaceuticals Inc | FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) BINDING PROTEINS |
| ES2637411T3 (es) | 2008-12-01 | 2017-10-13 | Laboratory Corporation Of America Holdings | Métodos y ensayos para medir p95 Y/O p95 en una muestra y anticuerpos específicos para p95 |
| JP5746051B2 (ja) * | 2009-01-15 | 2015-07-08 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | Ｈｅｒ−３の測定による患者の反応を判定する方法 |
| JP2012515353A (ja) * | 2009-01-15 | 2012-07-05 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | Ｈｅｒ−２発現の測定による患者の反応を判定する方法 |
| US10266585B2 (en) | 2009-08-28 | 2019-04-23 | The Board Of Regents Of The Univerity Of Texas System | Methods of treating brain injury |
| US20120269814A1 (en) * | 2009-11-10 | 2012-10-25 | Amgen Inc. | Anti-c mpl antibodies |
| WO2012051498A2 (en) * | 2010-10-15 | 2012-04-19 | The Board Of Regents Of The University Of Texas System | Antibodies that bind amyloid oligomers |
| US9032525B2 (en) | 2011-03-29 | 2015-05-12 | Mcafee, Inc. | System and method for below-operating system trapping of driver filter attachment |
| US8925089B2 (en) | 2011-03-29 | 2014-12-30 | Mcafee, Inc. | System and method for below-operating system modification of malicious code on an electronic device |
| US9087199B2 (en) | 2011-03-31 | 2015-07-21 | Mcafee, Inc. | System and method for providing a secured operating system execution environment |
| US9317690B2 (en) | 2011-03-28 | 2016-04-19 | Mcafee, Inc. | System and method for firmware based anti-malware security |
| US8959638B2 (en) | 2011-03-29 | 2015-02-17 | Mcafee, Inc. | System and method for below-operating system trapping and securing of interdriver communication |
| US9262246B2 (en) | 2011-03-31 | 2016-02-16 | Mcafee, Inc. | System and method for securing memory and storage of an electronic device with a below-operating system security agent |
| US8813227B2 (en) | 2011-03-29 | 2014-08-19 | Mcafee, Inc. | System and method for below-operating system regulation and control of self-modifying code |
| US9038176B2 (en) | 2011-03-31 | 2015-05-19 | Mcafee, Inc. | System and method for below-operating system trapping and securing loading of code into memory |
| US8966624B2 (en) | 2011-03-31 | 2015-02-24 | Mcafee, Inc. | System and method for securing an input/output path of an application against malware with a below-operating system security agent |
| US8966629B2 (en) | 2011-03-31 | 2015-02-24 | Mcafee, Inc. | System and method for below-operating system trapping of driver loading and unloading |
| US8863283B2 (en) | 2011-03-31 | 2014-10-14 | Mcafee, Inc. | System and method for securing access to system calls |
| US9255595B2 (en) * | 2011-04-29 | 2016-02-09 | Bae Systems Information And Electronic Systems Integration Inc. | Optical dome bezel |
| EP2791686B1 (en) * | 2011-12-12 | 2017-02-15 | Oxford University Innovation Limited | Tenascin-c and use thereof in rheumatoid arthritis |
| JP6463331B2 (ja) | 2013-03-15 | 2019-01-30 | イントリンシック ライフサイエンシズ リミテッド ライアビリティ カンパニー | 抗ヘプシジン抗体およびその使用 |
| GB201414021D0 (en) * | 2014-08-07 | 2014-09-24 | Nascient Ltd | Biological materials and uses thereof |
| AU2015321462B2 (en) | 2014-09-22 | 2020-04-30 | Intrinsic Lifesciences Llc | Humanized anti-hepcidin antibodies and uses thereof |
| GB201602413D0 (en) * | 2016-02-10 | 2016-03-23 | Nascient Ltd | Method |
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| US4687732A (en) | 1983-06-10 | 1987-08-18 | Yale University | Visualization polymers and their application to diagnostic medicine |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| WO1994021293A1 (en) * | 1993-03-19 | 1994-09-29 | Duke University | Method of treatment of tumors with an antibody binding to tenascin |
| US5482698A (en) | 1993-04-22 | 1996-01-09 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin polymer conjugates |
| CA2163976C (en) | 1993-05-28 | 2010-06-29 | Didier J. Leturcq | Methods and compositions for inhibiting cd14 mediated cell activation |
| US6335014B1 (en) | 1998-06-17 | 2002-01-01 | The Institute Of Physical And Chemical Research | Medicament for suppressing cancer metastasis |
| ITRM20020128A1 (it) | 2002-03-08 | 2003-09-08 | Sigma Tau Ind Farmaceuti | Dimeri di avidina efficaci nell'incrementare la concentrazione di biotina radioattiva nella immunoterapia con "pretargeting". |
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- 2003-02-20 KR KR1020047013068A patent/KR101048894B1/ko not_active Expired - Fee Related
- 2003-02-20 CN CNB038046342A patent/CN1317303C/zh not_active Expired - Fee Related
- 2003-02-20 AT AT03743010T patent/ATE480564T1/de active
- 2003-02-20 JP JP2003571313A patent/JP4488746B2/ja not_active Expired - Lifetime
- 2003-02-20 MX MXPA04008216A patent/MXPA04008216A/es active IP Right Grant
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- 2003-02-20 PL PL372803A patent/PL213216B1/pl unknown
- 2003-02-20 SI SI200331899T patent/SI1478667T1/sl unknown
- 2003-02-20 AU AU2003215900A patent/AU2003215900B2/en not_active Ceased
- 2003-02-20 ES ES03743010T patent/ES2352180T3/es not_active Expired - Lifetime
- 2003-02-20 PT PT03743010T patent/PT1478667E/pt unknown
- 2003-02-20 US US10/505,747 patent/US7438908B2/en not_active Expired - Lifetime
- 2003-02-20 DK DK03743010.5T patent/DK1478667T3/da active
- 2003-02-25 US US10/372,719 patent/US20040005643A1/en not_active Abandoned
- 2003-02-26 AR ARP030100622A patent/AR038700A1/es not_active Application Discontinuation
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- 2008-09-17 US US12/232,431 patent/US8048417B2/en not_active Expired - Fee Related
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2010
- 2010-12-01 CY CY20101101107T patent/CY1111108T1/el unknown
Also Published As
| Publication number | Publication date |
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| US7438908B2 (en) | 2008-10-21 |
| AR038700A1 (es) | 2005-01-26 |
| EP1478667A1 (en) | 2004-11-24 |
| ES2352180T3 (es) | 2011-02-16 |
| CN1639192A (zh) | 2005-07-13 |
| SI1478667T1 (sl) | 2010-12-31 |
| BR0307994A (pt) | 2004-12-07 |
| JP2005534615A (ja) | 2005-11-17 |
| US8048417B2 (en) | 2011-11-01 |
| DE60334076D1 (de) | 2010-10-21 |
| EP1478667B1 (en) | 2010-09-08 |
| US20110020219A1 (en) | 2011-01-27 |
| PL213216B1 (pl) | 2013-01-31 |
| ATE480564T1 (de) | 2010-09-15 |
| AU2003215900A1 (en) | 2003-09-09 |
| CY1111108T1 (el) | 2015-06-11 |
| WO2003072608A1 (en) | 2003-09-04 |
| KR101048894B1 (ko) | 2011-07-13 |
| PT1478667E (pt) | 2010-12-09 |
| JP4488746B2 (ja) | 2010-06-23 |
| HK1078589A1 (en) | 2006-03-17 |
| DK1478667T3 (da) | 2010-12-20 |
| CN1317303C (zh) | 2007-05-23 |
| AU2003215900B2 (en) | 2008-09-25 |
| US20040005643A1 (en) | 2004-01-08 |
| KR20040086426A (ko) | 2004-10-08 |
| MXPA04008216A (es) | 2004-11-26 |
| US20050106145A1 (en) | 2005-05-19 |
| CA2475395A1 (en) | 2003-09-04 |
| PL372803A1 (en) | 2005-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20210222 |