CA2464735A1 - Solution d'inhalation a base d'albuterol et d'ipratropium, et systeme, kit et methode permettant de soulager les symptomes de la bronchopneumopathie chronique obstructive - Google Patents
Solution d'inhalation a base d'albuterol et d'ipratropium, et systeme, kit et methode permettant de soulager les symptomes de la bronchopneumopathie chronique obstructive Download PDFInfo
- Publication number
- CA2464735A1 CA2464735A1 CA002464735A CA2464735A CA2464735A1 CA 2464735 A1 CA2464735 A1 CA 2464735A1 CA 002464735 A CA002464735 A CA 002464735A CA 2464735 A CA2464735 A CA 2464735A CA 2464735 A1 CA2464735 A1 CA 2464735A1
- Authority
- CA
- Canada
- Prior art keywords
- solution
- albuterol
- inhalation solution
- containers
- nebulizer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Solution d'inhalation à base de deux bronchodilatateurs, et système, kit et méthode permettant de soulager le bronchospasme chez les patients souffrant de bronchopneumopathie chronique obstructive. Dans un mode de réalisation, la solution selon la présente invention est une dose unitaire préemballée, stérile, prémélangée et prémesurée d'albutérol et de bromure d'ipratropium pour des patients souffrant de bronchopneumopathie chronique obstructive. Cette solution peut être exempte de produits chimiques anti-microbiens tels que le chlorure de benzalconium. Dans un autre mode de réalisation, la solution selon la présente invention contient environ 2,50 mg d'albutérol et environ 0,50 mg de bromure d'ipratropium.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34607801P | 2001-10-26 | 2001-10-26 | |
US60/346,078 | 2001-10-26 | ||
US10/034,657 | 2001-12-27 | ||
US3465701A | 2001-12-28 | 2001-12-28 | |
AU32974/02 | 2002-04-05 | ||
AU32974/02A AU3297402A (en) | 2001-10-26 | 2002-04-05 | An albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
JP2002158304A JP2003221335A (ja) | 2001-10-26 | 2002-04-23 | 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法 |
JP2002-158304 | 2002-04-23 | ||
PCT/US2002/033353 WO2003037159A2 (fr) | 2001-10-26 | 2002-10-18 | Solution d'inhalation a base d'albuterol et d'ipratropium, et systeme, kit et methode permettant de soulager les symptomes de la bronchopneumopathie chronique obstructive |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2464735A1 true CA2464735A1 (fr) | 2003-05-08 |
CA2464735C CA2464735C (fr) | 2011-03-22 |
Family
ID=27422968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2464735A Expired - Fee Related CA2464735C (fr) | 2001-10-26 | 2002-10-18 | Solution d'inhalation a base d'albuterol et d'ipratropium, et systeme, kit et methode permettant de soulager les symptomes de la bronchopneumopathie chronique obstructive |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1446045A4 (fr) |
JP (1) | JP2006505486A (fr) |
CN (2) | CN1939279A (fr) |
AU (1) | AU3297402A (fr) |
CA (1) | CA2464735C (fr) |
MX (1) | MXPA04003927A (fr) |
NZ (1) | NZ552548A (fr) |
WO (1) | WO2003037159A2 (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1915985A1 (fr) * | 2003-03-20 | 2008-04-30 | Boehringer Ingelheim Pharmaceuticals Inc. | Formulation pour une dose mesurée utilisant des hydro-fluoro-alcanes en tant que propulseurs |
GB0501956D0 (en) * | 2005-01-31 | 2005-03-09 | Arrow Internat | Nebulizer formulation |
WO2007137206A2 (fr) * | 2006-05-18 | 2007-11-29 | Tika Läkemedel Ab | Préparations de doses unitaires comprenant une solution inhalable d'albutérol |
US20100056559A1 (en) | 2006-05-19 | 2010-03-04 | Boehringer Ingelheim International Gmbh | Propellant-free aerosol formulation for inhalation |
WO2007134965A1 (fr) * | 2006-05-19 | 2007-11-29 | Boehringer Ingelheim International Gmbh | Formulation d'aérosol contenant du bromure d'ipratropium et du sulfate de salbutamol |
EP2077132A1 (fr) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispositif distributeur, dispositif de stockage et procédé pour la distribution d'une formulation |
EP2414560B1 (fr) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Procédé de revêtement d'une surface d'un composant |
WO2010133294A2 (fr) | 2009-05-18 | 2010-11-25 | Boehringer Ingelheim International Gmbh | Adapteur, dispositif d'inhalation et nébuliseur |
MX2012005961A (es) | 2009-11-25 | 2012-06-14 | Boehringer Ingelheim Int | Nebulizador. |
US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2011064163A1 (fr) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nébuliseur |
JP5874724B2 (ja) | 2010-06-24 | 2016-03-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
EP2670242B1 (fr) * | 2011-01-31 | 2022-03-16 | Avalyn Pharma Inc. | Composés analogues de pyridone et de pirfénidone en aérosol, et leurs utilisations |
EP2694220B1 (fr) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Appareil médical pourvu d'un récipient |
US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2013152894A1 (fr) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Pulvérisateur comprenant des moyens de détrompage |
EP3030298B1 (fr) | 2013-08-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Nébuliseur |
EP2835146B1 (fr) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Atomiseur |
JP2016539126A (ja) * | 2013-11-22 | 2016-12-15 | テバ ブランデッド ファーマシューティカル プロダクツ アール アンド ディー インコーポレイテッド | 吸引可能薬剤 |
CA2930170A1 (fr) | 2013-11-22 | 2015-05-28 | Teva Branded Pharmaceutical Products R&D, Inc. | Medicament inhalable |
DK3139982T3 (da) | 2014-05-07 | 2022-05-16 | Boehringer Ingelheim Int | Forstøver |
PL3139979T3 (pl) | 2014-05-07 | 2023-12-27 | Boehringer Ingelheim International Gmbh | Jednostka, nebulizator i sposób |
EP3139984B1 (fr) | 2014-05-07 | 2021-04-28 | Boehringer Ingelheim International GmbH | Nébuliseur |
CN106344544A (zh) * | 2016-08-25 | 2017-01-25 | 杭州百诚医药科技股份有限公司 | 一种用于治疗支气管哮喘的雾化吸入制剂 |
CN110898042B (zh) * | 2019-12-12 | 2020-10-16 | 深圳大佛药业股份有限公司 | 一种吸入用硫酸沙丁胺醇溶液剂及其制备方法 |
CN111053761B (zh) * | 2020-01-16 | 2022-05-03 | 杭州旦承医药科技有限公司 | 一种吸入用双膦酸类药物及其制备方法及其在慢性阻塞性肺疾病的用途 |
WO2021188809A1 (fr) * | 2020-03-19 | 2021-09-23 | Cai Gu Huang | Formulation inhalable d'une solution contenant du tartrate de lévalbutérol |
CN113018280A (zh) * | 2021-03-01 | 2021-06-25 | 石家庄四药有限公司 | 一种异丙托溴铵吸入用溶液制剂及其制备方法 |
CN115645381B (zh) * | 2022-10-20 | 2023-05-30 | 深圳大佛药业股份有限公司 | 一种盐酸左沙丁胺醇雾化吸入溶液缓释剂及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994013262A1 (fr) * | 1992-12-09 | 1994-06-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Formulations de solutions medicinales aerosol stabilisees |
DE19653969A1 (de) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
US6247617B1 (en) * | 1999-12-13 | 2001-06-19 | Richard Allen Clyde | Single use container for dispensing separately housed sterile compositions |
-
2002
- 2002-04-05 AU AU32974/02A patent/AU3297402A/en not_active Abandoned
- 2002-10-18 WO PCT/US2002/033353 patent/WO2003037159A2/fr active Application Filing
- 2002-10-18 CN CNA2006101077523A patent/CN1939279A/zh active Pending
- 2002-10-18 JP JP2003539509A patent/JP2006505486A/ja active Pending
- 2002-10-18 CA CA2464735A patent/CA2464735C/fr not_active Expired - Fee Related
- 2002-10-18 MX MXPA04003927A patent/MXPA04003927A/es active IP Right Grant
- 2002-10-18 CN CNA028262263A patent/CN1607940A/zh active Pending
- 2002-10-18 EP EP02789216A patent/EP1446045A4/fr not_active Withdrawn
- 2002-10-18 NZ NZ552548A patent/NZ552548A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2003037159A3 (fr) | 2003-10-16 |
CN1607940A (zh) | 2005-04-20 |
CN1939279A (zh) | 2007-04-04 |
MXPA04003927A (es) | 2005-03-31 |
JP2006505486A (ja) | 2006-02-16 |
WO2003037159A2 (fr) | 2003-05-08 |
NZ552548A (en) | 2009-03-31 |
CA2464735C (fr) | 2011-03-22 |
EP1446045A4 (fr) | 2010-07-21 |
EP1446045A2 (fr) | 2004-08-18 |
AU3297402A (en) | 2003-10-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20201019 |