CA2459789A1 - 3-desoxy-vitamin d3 analog esters - Google Patents

3-desoxy-vitamin d3 analog esters Download PDF

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Publication number
CA2459789A1
CA2459789A1 CA002459789A CA2459789A CA2459789A1 CA 2459789 A1 CA2459789 A1 CA 2459789A1 CA 002459789 A CA002459789 A CA 002459789A CA 2459789 A CA2459789 A CA 2459789A CA 2459789 A1 CA2459789 A1 CA 2459789A1
Authority
CA
Canada
Prior art keywords
compound
formula
group
desoxy
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002459789A
Other languages
English (en)
French (fr)
Inventor
Milan Radoje Uskokovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2459789A1 publication Critical patent/CA2459789A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002459789A 2001-09-21 2002-09-12 3-desoxy-vitamin d3 analog esters Abandoned CA2459789A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US32395701P 2001-09-21 2001-09-21
US32387001P 2001-09-21 2001-09-21
US60/323,870 2001-09-21
US60/323,957 2001-09-21
PCT/EP2002/010233 WO2003027065A1 (en) 2001-09-21 2002-09-12 3-desoxy-vitamin d3 analog esters

Publications (1)

Publication Number Publication Date
CA2459789A1 true CA2459789A1 (en) 2003-04-03

Family

ID=26984180

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002459789A Abandoned CA2459789A1 (en) 2001-09-21 2002-09-12 3-desoxy-vitamin d3 analog esters

Country Status (14)

Country Link
EP (1) EP1430026A1 (ru)
JP (1) JP2005503434A (ru)
KR (1) KR100628586B1 (ru)
CN (1) CN1285573C (ru)
AU (1) AU2002338672B2 (ru)
BR (1) BR0212719A (ru)
CA (1) CA2459789A1 (ru)
MX (1) MXPA04002640A (ru)
PA (1) PA8554901A1 (ru)
PE (1) PE20030429A1 (ru)
PL (1) PL370352A1 (ru)
RU (1) RU2296121C2 (ru)
UY (1) UY27448A1 (ru)
WO (1) WO2003027065A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037781A1 (en) * 2002-10-23 2004-05-06 Leo Pharma A/S Vitamin d analogues, compositions comprising said analogues and their use
US20080318911A1 (en) * 2004-09-24 2008-12-25 Bioxell S.P.A. 20-Cyclopropyl, 26,27-Alkyl/Haloalkyl Vitamin D3 Compounds and Methods of Use Thereof
AU2005303773A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer
CN102124301B (zh) 2008-08-22 2014-04-02 Nxp股份有限公司 基于位置的服务
CN110339205B (zh) * 2019-08-19 2021-08-24 山东德信生物科技有限公司 富氢水组合物在抑制六价铬诱导的df-1细胞内质网应激及自噬中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG70010A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Fluorinated vitamin d3 analogs
WO1999012894A1 (en) * 1997-09-08 1999-03-18 F. Hoffmann-La Roche Ag 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs

Also Published As

Publication number Publication date
UY27448A1 (es) 2003-03-31
RU2004112217A (ru) 2005-07-10
BR0212719A (pt) 2004-08-03
PE20030429A1 (es) 2003-05-15
CN1285573C (zh) 2006-11-22
PA8554901A1 (es) 2003-12-10
CN1556795A (zh) 2004-12-22
AU2002338672B2 (en) 2006-03-09
MXPA04002640A (es) 2004-06-07
EP1430026A1 (en) 2004-06-23
PL370352A1 (en) 2005-05-16
WO2003027065A1 (en) 2003-04-03
KR20040035853A (ko) 2004-04-29
RU2296121C2 (ru) 2007-03-27
KR100628586B1 (ko) 2006-09-26
JP2005503434A (ja) 2005-02-03

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued