CA2457629C - Device for extracting gas or liquid from microfluidic through-flow systems - Google Patents
Device for extracting gas or liquid from microfluidic through-flow systems Download PDFInfo
- Publication number
- CA2457629C CA2457629C CA002457629A CA2457629A CA2457629C CA 2457629 C CA2457629 C CA 2457629C CA 002457629 A CA002457629 A CA 002457629A CA 2457629 A CA2457629 A CA 2457629A CA 2457629 C CA2457629 C CA 2457629C
- Authority
- CA
- Canada
- Prior art keywords
- hollow body
- microfluidic
- inlet opening
- outlet opening
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 74
- 239000012530 fluid Substances 0.000 claims abstract description 33
- 239000007789 gas Substances 0.000 claims description 62
- 239000011796 hollow space material Substances 0.000 claims description 34
- 238000001690 micro-dialysis Methods 0.000 claims description 26
- 239000000523 sample Substances 0.000 claims description 9
- 239000000126 substance Substances 0.000 claims description 8
- 238000013461 design Methods 0.000 claims description 6
- 238000011144 upstream manufacturing Methods 0.000 claims description 4
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- 239000007791 liquid phase Substances 0.000 claims 2
- 230000007423 decrease Effects 0.000 claims 1
- 239000007792 gaseous phase Substances 0.000 claims 1
- 238000000926 separation method Methods 0.000 description 32
- 238000000034 method Methods 0.000 description 13
- 239000012491 analyte Substances 0.000 description 11
- 238000004519 manufacturing process Methods 0.000 description 11
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 8
- 239000008103 glucose Substances 0.000 description 8
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- 229920003023 plastic Polymers 0.000 description 7
- 238000004458 analytical method Methods 0.000 description 6
- 210000001124 body fluid Anatomy 0.000 description 6
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- 210000004369 blood Anatomy 0.000 description 4
- 108010015776 Glucose oxidase Proteins 0.000 description 3
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- 239000003570 air Substances 0.000 description 3
- 239000011888 foil Substances 0.000 description 3
- 229940116332 glucose oxidase Drugs 0.000 description 3
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- 238000010276 construction Methods 0.000 description 2
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- 238000001746 injection moulding Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
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- 229910052751 metal Inorganic materials 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 238000000108 ultra-filtration Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010017711 Gangrene Diseases 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
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- 238000007796 conventional method Methods 0.000 description 1
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- 210000003722 extracellular fluid Anatomy 0.000 description 1
- 230000003345 hyperglycaemic effect Effects 0.000 description 1
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- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
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- 238000005191 phase separation Methods 0.000 description 1
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00788—Three-dimensional assemblies, i.e. the reactor comprising a form other than a stack of plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00891—Feeding or evacuation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00905—Separation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Degasification And Air Bubble Elimination (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Jet Pumps And Other Pumps (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10140565.0 | 2001-08-18 | ||
| DE10140565A DE10140565B4 (de) | 2001-08-18 | 2001-08-18 | Vorrichtung zur Gas- oder Flüssigkeitsabscheidung aus microfluidischen Durchflusssystemen |
| PCT/EP2002/009040 WO2003015919A2 (de) | 2001-08-18 | 2002-08-13 | Vorrichtung zur gas-oder flüssigkeitsabscheidung aus microfluidischen durchflusssystemen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2457629A1 CA2457629A1 (en) | 2003-02-27 |
| CA2457629C true CA2457629C (en) | 2008-07-15 |
Family
ID=7695875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002457629A Expired - Fee Related CA2457629C (en) | 2001-08-18 | 2002-08-13 | Device for extracting gas or liquid from microfluidic through-flow systems |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7682430B2 (enExample) |
| EP (1) | EP1425100A2 (enExample) |
| JP (1) | JP4113841B2 (enExample) |
| AU (1) | AU2002327829A1 (enExample) |
| CA (1) | CA2457629C (enExample) |
| DE (1) | DE10140565B4 (enExample) |
| WO (1) | WO2003015919A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100534619C (zh) | 2004-10-15 | 2009-09-02 | 西门子公司 | 对可通过导管进入测量室中的液态测量样品进行电化学测量的方法和相应的布置 |
| CA2610875A1 (en) | 2005-06-06 | 2006-12-14 | Decision Biomarkers, Inc. | Assays based on liquid flow over arrays |
| DE102007023619B4 (de) * | 2007-05-18 | 2009-07-02 | Samsung SDI Co., Ltd., Suwon | Mischer mit integrierter Gasabscheidevorrichtung und Gas-/Flüssigkeitsabscheider für Direktmethanol-Brennstoffzellensysteme |
| US20090044604A1 (en) * | 2007-08-15 | 2009-02-19 | Gregor Ocvirk | Portable Measuring Facility for Determining A Medically Significant Analyte Concentration |
| US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
| US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
| CA2737461A1 (en) | 2008-09-19 | 2010-03-25 | Tandem Diabetes Care, Inc. | Solute concentration measurement device and related methods |
| EP2346604A1 (en) * | 2008-11-13 | 2011-07-27 | Koninklijke Philips Electronics N.V. | Interfacing an inlet to a capillary channel of a microfluidic system |
| CA2921304C (en) | 2009-07-30 | 2018-06-05 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
| US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
| EP2985063A1 (en) * | 2014-08-15 | 2016-02-17 | Carpegen GmbH | Device for separating bubbles from a fluid |
| ES2667430B1 (es) * | 2016-10-05 | 2019-02-20 | Univ Zaragoza | Dispositivo conector para circuitos microfluidicos |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3744492A (en) | 1971-04-07 | 1973-07-10 | S Leibinsohn | Drip chamber |
| US3926594A (en) | 1975-01-06 | 1975-12-16 | Us Navy | Water trap for pitot static system |
| DE2634121C2 (de) * | 1975-08-28 | 1983-05-05 | Helmut Dr. 6020 Innsbruck Biedermann | Tropfkammer |
| AT356796B (de) | 1976-05-24 | 1980-05-27 | Biedermann Helmut | Tropfkammer |
| US4304578A (en) | 1978-09-01 | 1981-12-08 | Instrumentarium Oy | Water separator for a gas analyzer |
| IL77109A0 (en) * | 1985-11-20 | 1986-04-29 | Leibinsohn Saul | Drip chamber for infusion apparatus |
| US5059790A (en) | 1990-03-30 | 1991-10-22 | Fiberchem, Inc. | Reservoir fiber optic chemical sensors |
| US5190515A (en) * | 1992-01-13 | 1993-03-02 | Eastman Kodak Company | Vacuum degassing apparatus |
| US5290237A (en) * | 1992-01-17 | 1994-03-01 | Verkaart Wesley H | Orientation-independent device for removal of gas from a cellular fluid |
| JPH0623758A (ja) | 1992-07-03 | 1994-02-01 | Sutaaraito Kogyo Kk | 合成樹脂中空体の製造方法 |
| US5830185A (en) * | 1995-10-12 | 1998-11-03 | Instrumentarium Corp. | Position-independent fluid trap |
| US5674200A (en) | 1996-02-05 | 1997-10-07 | Filtertek Inc. | Air eliminator |
| JPH10315266A (ja) | 1997-05-21 | 1998-12-02 | Kojima Press Co Ltd | 樹脂成形中空体 |
| US6013060A (en) | 1997-11-19 | 2000-01-11 | Woodard; Robert W. | Intravenous liquid flow regulator |
| DE10010587A1 (de) * | 2000-03-03 | 2001-09-06 | Roche Diagnostics Gmbh | System zur Bestimmung von Analytkonzentrationen in Körperflüssigkeiten |
| JP2001324975A (ja) | 2000-05-15 | 2001-11-22 | Fuji Xerox Co Ltd | 画像処理装置 |
-
2001
- 2001-08-18 DE DE10140565A patent/DE10140565B4/de not_active Expired - Fee Related
-
2002
- 2002-08-13 US US10/487,101 patent/US7682430B2/en not_active Expired - Fee Related
- 2002-08-13 JP JP2003520467A patent/JP4113841B2/ja not_active Expired - Fee Related
- 2002-08-13 CA CA002457629A patent/CA2457629C/en not_active Expired - Fee Related
- 2002-08-13 WO PCT/EP2002/009040 patent/WO2003015919A2/de not_active Ceased
- 2002-08-13 AU AU2002327829A patent/AU2002327829A1/en not_active Abandoned
- 2002-08-13 EP EP02762441A patent/EP1425100A2/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2457629A1 (en) | 2003-02-27 |
| DE10140565A1 (de) | 2003-03-06 |
| AU2002327829A1 (en) | 2003-03-03 |
| WO2003015919A2 (de) | 2003-02-27 |
| DE10140565B4 (de) | 2006-06-29 |
| WO2003015919A3 (de) | 2003-11-06 |
| JP2004538136A (ja) | 2004-12-24 |
| US7682430B2 (en) | 2010-03-23 |
| EP1425100A2 (de) | 2004-06-09 |
| US20050000364A1 (en) | 2005-01-06 |
| JP4113841B2 (ja) | 2008-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |