CA2457432A1 - Method and system for profiling biological systems - Google Patents

Method and system for profiling biological systems Download PDF

Info

Publication number
CA2457432A1
CA2457432A1 CA002457432A CA2457432A CA2457432A1 CA 2457432 A1 CA2457432 A1 CA 2457432A1 CA 002457432 A CA002457432 A CA 002457432A CA 2457432 A CA2457432 A CA 2457432A CA 2457432 A1 CA2457432 A1 CA 2457432A1
Authority
CA
Canada
Prior art keywords
analysis
data sets
correlation
sets
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002457432A
Other languages
English (en)
French (fr)
Inventor
Jan Van Der Greef
Eric K. Neumann
Aram S. Adourian
Noubar B. Afeyan
Matej Oresic
Frederick E. Regnier
Elwin Robbert Verheij
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BG Medicine Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2457432A1 publication Critical patent/CA2457432A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0027Methods for using particle spectrometers
    • H01J49/0036Step by step routines describing the handling of the data generated during a measurement
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioethics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Signal Processing (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002457432A 2001-08-13 2002-08-13 Method and system for profiling biological systems Abandoned CA2457432A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31214501P 2001-08-13 2001-08-13
US60/312,145 2001-08-13
PCT/US2002/025734 WO2003017177A2 (en) 2001-08-13 2002-08-13 Method and system for profiling biological systems

Publications (1)

Publication Number Publication Date
CA2457432A1 true CA2457432A1 (en) 2003-02-27

Family

ID=23210073

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002457432A Abandoned CA2457432A1 (en) 2001-08-13 2002-08-13 Method and system for profiling biological systems

Country Status (6)

Country Link
US (3) US8068987B2 (cg-RX-API-DMAC7.html)
EP (1) EP1425695A2 (cg-RX-API-DMAC7.html)
JP (2) JP2005500543A (cg-RX-API-DMAC7.html)
CA (1) CA2457432A1 (cg-RX-API-DMAC7.html)
IL (1) IL160324A0 (cg-RX-API-DMAC7.html)
WO (1) WO2003017177A2 (cg-RX-API-DMAC7.html)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2298181C (en) * 2000-02-02 2006-09-19 Dayan Burke Goodnough Non-targeted complex sample analysis
DE60135549D1 (de) 2000-06-19 2008-10-09 Correlogic Systems Inc Heuristisches klassifikationsverfahren
CN1484806A (zh) * 2000-07-18 2004-03-24 �����弪��ϵͳ��˾ 基于隐含模式用于从生物数据中识别生物状态的方法
WO2003017177A2 (en) 2001-08-13 2003-02-27 Beyong Genomics, Inc. Method and system for profiling biological systems
TW200407543A (en) * 2002-07-29 2004-05-16 Correlogic Systems Inc Quality assurance/quality control for high throughput bioassay process
US9740817B1 (en) 2002-10-18 2017-08-22 Dennis Sunga Fernandez Apparatus for biological sensing and alerting of pharmaco-genomic mutation
WO2004052191A1 (ja) 2002-12-09 2004-06-24 Ajinomoto Co., Inc. 生体状態情報処理装置、生体状態情報処理方法、生体状態情報管理システム、プログラム、および、記録媒体
US7457708B2 (en) * 2003-03-13 2008-11-25 Agilent Technologies Inc Methods and devices for identifying related ions from chromatographic mass spectral datasets containing overlapping components
AU2003901196A0 (en) * 2003-03-17 2003-04-03 Commonwealth Scientific And Industrial Research Organisation Analysis method
GB0307352D0 (en) 2003-03-29 2003-05-07 Qinetiq Ltd Improvements in and relating to the analysis of compounds
US20040236603A1 (en) * 2003-05-22 2004-11-25 Biospect, Inc. System of analyzing complex mixtures of biological and other fluids to identify biological state information
US7425700B2 (en) * 2003-05-22 2008-09-16 Stults John T Systems and methods for discovery and analysis of markers
WO2004106915A1 (en) * 2003-05-29 2004-12-09 Waters Investments Limited Method and device for processing of lc-ms or lc-ms/ms data in metabonomics
MXPA06001170A (es) * 2003-08-01 2006-05-15 Correlogic Systems Inc Caracteristicas proteomicas de suero de alta resolucion multiples para deteccion de cancer de ovarios.
WO2005020125A2 (en) * 2003-08-20 2005-03-03 Bg Medicine, Inc. Methods and systems for profiling biological systems
US8346482B2 (en) 2003-08-22 2013-01-01 Fernandez Dennis S Integrated biosensor and simulation system for diagnosis and therapy
EP1512970A1 (en) * 2003-09-05 2005-03-09 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Method for determining the impact of a multicomponent mixture on the biological profile of a disease
JP4774534B2 (ja) * 2003-12-11 2011-09-14 アングーク ファーマシューティカル カンパニー,リミティド 集中化適応モデル及び遠隔操作サンプルプロセッシングの使用を介した生物学的状態の診断方法
CA2501003C (en) 2004-04-23 2009-05-19 F. Hoffmann-La Roche Ag Sample analysis to provide characterization data
US20050244973A1 (en) * 2004-04-29 2005-11-03 Predicant Biosciences, Inc. Biological patterns for diagnosis and treatment of cancer
US8685659B2 (en) 2005-01-28 2014-04-01 Children's Medical Center Corporation Method for diagnosis and prognosis of epithelial cancers
US20070003996A1 (en) * 2005-02-09 2007-01-04 Hitt Ben A Identification of bacteria and spores
EP1862797A4 (en) * 2005-03-16 2009-09-16 Ajinomoto Kk DEVICE, METHOD, SYSTEM AND PROGRAM FOR EVALUATING BIOLOGICAL STATES, DEVICE, METHOD AND PROGRAM FOR GENERATING AN EVALUATION FUNCTION AND RECORDING MEDIUM
WO2006124628A2 (en) * 2005-05-12 2006-11-23 Correlogic Systems, Inc. A model for classifying a biological sample in relation to breast cancer based on mass spectral data
JP5038311B2 (ja) 2005-09-12 2012-10-03 フェノメノーム ディスカバリーズ インク ビタミンe関連代謝産物の測定による、結腸直腸癌及び卵巣癌の診断方法
US20070162992A1 (en) * 2006-01-09 2007-07-12 Mcgill University Metabolomic determination in assisted reproductive technology
CA2642833A1 (en) 2006-02-17 2007-08-30 Children's Medical Center Corporation Free ngal as a biomarker for cancer
US7736905B2 (en) 2006-03-31 2010-06-15 Biodesix, Inc. Method and system for determining whether a drug will be effective on a patient with a disease
WO2007140270A2 (en) * 2006-05-25 2007-12-06 Vialogy Corp. Analyzing information gathered using multiple analytical techniques
WO2008100941A2 (en) * 2007-02-12 2008-08-21 Correlogic Systems Inc. A method for calibrating an analytical instrument
EP2538049B1 (en) 2007-03-30 2015-03-18 Continental Automotive Systems US, Inc. Reductant delivery unit for selective catalytic reduction
AU2008268461B2 (en) 2007-06-22 2015-04-09 Children's Medical Center Corporation Methods and uses thereof of prosaposin
KR20120087885A (ko) 2007-06-29 2012-08-07 안국약품 주식회사 난소암의 예측 마커
JP4983451B2 (ja) * 2007-07-18 2012-07-25 株式会社島津製作所 クロマトグラフ質量分析データ処理装置
US20100099135A1 (en) * 2008-10-22 2010-04-22 Mandy Katz-Jaffe Methods and assays for assessing the quality of embryos in assisted reproduction technology protocols
JP5436446B2 (ja) * 2008-12-01 2014-03-05 国立大学法人山口大学 薬剤の作用・副作用予測システムとそのプログラム
ES2573954T3 (es) 2008-12-30 2016-06-13 Children's Medical Center Corporation Método de predicción de apendicitis aguda
WO2010079253A2 (es) 2009-01-09 2010-07-15 Proyecto De Biomedicina Cima, S.L. Biomarcadores para el diagnóstico de fibrosis
AU2010339794B2 (en) 2009-12-17 2016-09-22 Children's Medical Center Corporation Saposin-A derived peptides and uses thereof
KR101149236B1 (ko) * 2010-04-09 2012-05-25 대한민국(농촌진흥청장) 크로마토그래피?질량분석을 이용한 인삼 연근 판별 방법
EP2583107A2 (en) * 2010-06-20 2013-04-24 Zora Biosciences OY Lipidomic biomarkers for identification of high-risk coronary artery disease patients
JP2013545439A (ja) 2010-09-17 2013-12-26 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 多能性幹細胞の有用性および安全性の特徴決定を行うための機能的ゲノミクスアッセイ
DE102010038014B4 (de) * 2010-10-06 2021-10-07 Numares Ag Verwendung spezifischer Substanzen als Marker zur Bestimmung des Risikos einer Nierenabstoßung
CN102478563B (zh) * 2010-11-25 2014-08-13 中国科学院大连化学物理研究所 一种用于研究转基因和非转基因水稻代谢差异的方法
JP2014527036A (ja) 2011-06-27 2014-10-09 ザ ジャクソン ラボラトリー 癌および自己免疫疾患の処置のための方法および組成物
US10378060B2 (en) 2011-10-14 2019-08-13 Dana-Farber Cancer Institute, Inc. ZNF365/ZFP365 biomarker predictive of anti-cancer response
RU2622082C2 (ru) 2011-11-14 2017-06-09 Нестек С.А. Анализы и способы выбора режима лечения пациента с депрессией
US10736935B2 (en) 2011-12-22 2020-08-11 Children's Medical Center Corporation Saposin-A derived peptides and uses thereof
MX351313B (es) 2012-01-05 2017-10-10 Boston Medical Ct Corp Señalización de slit-robo para diagnosis y tratamiento de enfermedad del riñón.
AU2012367247B2 (en) 2012-01-24 2018-04-05 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
CN103913698B (zh) * 2014-03-27 2016-07-06 西北工业大学 基于小波分形及核主元特征的开关电流电路故障诊断方法
US11624093B2 (en) 2014-04-24 2023-04-11 Dana-Farber Cancer Institute, Inc. Tumor suppressor and oncogene biomarkers predictive of anti-immune checkpoint inhibitor response
KR20170020463A (ko) 2014-06-19 2017-02-22 메모리얼 슬로안-케터링 캔서 센터 Ezh2 저해제에의 반응에 대한 바이오마커
WO2016011383A1 (en) 2014-07-17 2016-01-21 The Trustees Of The University Of Pennsylvania Methods for using exosomes to monitor transplanted organ status
AU2016301231A1 (en) 2015-08-04 2018-02-22 Cd Diagnostics, Inc. Methods for detecting adverse local tissue reaction (ALTR) necrosis
WO2017147186A1 (en) 2016-02-22 2017-08-31 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
CN106022373B (zh) * 2016-05-18 2019-04-23 江南大学 一种基于广义均值典型相关分析的图像识别方法
CN109187614B (zh) * 2018-09-27 2020-03-06 厦门大学 基于核磁共振和质谱的代谢组学数据融合方法及其应用
CN117233413A (zh) 2019-08-05 2023-12-15 禧尔公司 用于样品制备、数据生成和蛋白质冠分析的系统和方法
US12018279B2 (en) 2019-10-18 2024-06-25 The Trustees Of The University Of Pennsylvania Micro-engineered models of the human eye and methods of use
WO2022086852A2 (en) 2020-10-19 2022-04-28 Dana-Farber Cancer Institute, Inc. Germline biomarkers of clinical response and benefit to immune checkpoint inhibitor therapy
CA3209638A1 (en) 2021-02-25 2022-09-01 Lung Therapeutics, Inc. Biomarkers for the treatment of interstitial lung disease
EP4074820A1 (en) 2021-04-16 2022-10-19 The Trustees of The University of Pennsylvania Micro-engineered models of the human eye and methods of use

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194217B1 (en) 1980-01-14 2001-02-27 Esa, Inc. Method of diagnosing or categorizing disorders from biochemical profiles
US5644503A (en) 1994-03-28 1997-07-01 Hitachi, Ltd. Methods and apparatuses for analyzing multichannel chromatogram
JP3270290B2 (ja) * 1994-04-28 2002-04-02 株式会社日立製作所 マルチチャンネルクロマトグラムの解析方法及びデータ処理装置
US6031232A (en) 1995-11-13 2000-02-29 Bio-Rad Laboratories, Inc. Method for the detection of malignant and premalignant stages of cervical cancer
US6699710B1 (en) 1998-02-25 2004-03-02 The United States Of America As Represented By The Department Of Health And Human Services Tumor tissue microarrays for rapid molecular profiling
US6428956B1 (en) * 1998-03-02 2002-08-06 Isis Pharmaceuticals, Inc. Mass spectrometric methods for biomolecular screening
AU3367799A (en) 1998-03-30 1999-10-18 Esa Inc. Methodology for predicting and/or diagnosing disease
CA2362058A1 (en) * 1999-02-10 2000-08-17 Oxford Natural Products Plc Process for quality control and standardisation of medicinal plant products
US6647341B1 (en) 1999-04-09 2003-11-11 Whitehead Institute For Biomedical Research Methods for classifying samples and ascertaining previously unknown classes
US6743576B1 (en) 1999-05-14 2004-06-01 Cytokinetics, Inc. Database system for predictive cellular bioinformatics
AU2579401A (en) * 1999-12-17 2001-06-25 Johns Hopkins University, The Brain protein markers
ATE516497T1 (de) 2000-03-06 2011-07-15 Asterand Acquisition Llc Screening für funktionshomologien
GB0013007D0 (en) 2000-05-30 2000-07-19 Imperial College Characterization system and method
CN1484806A (zh) 2000-07-18 2004-03-24 �����弪��ϵͳ��˾ 基于隐含模式用于从生物数据中识别生物状态的方法
NL1016034C2 (nl) 2000-08-03 2002-02-08 Tno Werkwijze en systeem voor het identificeren en kwantificeren van chemische componenten van een te onderzoeken mengsel van materialen.
AU2001292846A1 (en) 2000-09-20 2002-04-29 Surromed, Inc. Biological markers for evaluating therapeutic treatment of inflammatory and autoimmune disorders
US20030130798A1 (en) 2000-11-14 2003-07-10 The Institute For Systems Biology Multiparameter integration methods for the analysis of biological networks
JP2004522980A (ja) 2000-11-16 2004-07-29 シファーゲン バイオシステムズ, インコーポレイテッド 質量スペクトルを分析する方法
US20020095260A1 (en) * 2000-11-28 2002-07-18 Surromed, Inc. Methods for efficiently mining broad data sets for biological markers
GB0031566D0 (en) 2000-12-22 2001-02-07 Mets Ometrix Methods for spectral analysis and their applications
AU2002233310A1 (en) 2001-01-18 2002-07-30 Basf Aktiengesellschaft Method for metabolic profiling
US20040142496A1 (en) 2001-04-23 2004-07-22 Nicholson Jeremy Kirk Methods for analysis of spectral data and their applications: atherosclerosis/coronary heart disease
CA2445106A1 (en) 2001-04-23 2002-10-31 Metabometrix Limited Methods for analysis of spectral data and their applications: osteoporosis
US20050037515A1 (en) 2001-04-23 2005-02-17 Nicholson Jeremy Kirk Methods for analysis of spectral data and their applications osteoporosis
WO2002099452A1 (en) 2001-06-04 2002-12-12 Metabometrix Limited Methods for spectral analysis and their applications: reliability assessment
US7343247B2 (en) 2001-07-30 2008-03-11 The Institute For Systems Biology Methods of classifying drug responsiveness using multiparameter analysis
WO2003017177A2 (en) 2001-08-13 2003-02-27 Beyong Genomics, Inc. Method and system for profiling biological systems
US6873915B2 (en) 2001-08-24 2005-03-29 Surromed, Inc. Peak selection in multidimensional data
WO2003023366A2 (en) 2001-09-12 2003-03-20 The State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method and system for classifying a scenario
US20030078739A1 (en) 2001-10-05 2003-04-24 Surromed, Inc. Feature list extraction from data sets such as spectra
US6835927B2 (en) 2001-10-15 2004-12-28 Surromed, Inc. Mass spectrometric quantification of chemical mixture components
EP1481356A1 (en) 2001-11-21 2004-12-01 Paradigm Genetics Inc. Methods and systems for analyzing complex biological systems
EP1327883A3 (en) 2002-01-10 2003-07-30 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Combined metabolomic, proteomic and transcriptomic analysis from one, single sample and suitable statistical evaluation of data
US7623969B2 (en) 2002-01-31 2009-11-24 The Institute For Systems Biology Gene discovery for the system assignment of gene function
AU2003239409A1 (en) 2002-05-09 2003-11-11 Surromed, Inc. Methods for time-alignment of liquid chromatography-mass spectrometry data
IN2004DN03762A (cg-RX-API-DMAC7.html) 2002-06-14 2010-01-08 Pfizer
WO2004044554A2 (en) 2002-11-12 2004-05-27 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles

Also Published As

Publication number Publication date
US20050273275A1 (en) 2005-12-08
US20030134304A1 (en) 2003-07-17
US20050283320A1 (en) 2005-12-22
US8068987B2 (en) 2011-11-29
EP1425695A2 (en) 2004-06-09
JP2009133867A (ja) 2009-06-18
WO2003017177A3 (en) 2004-04-08
JP2005500543A (ja) 2005-01-06
WO2003017177A2 (en) 2003-02-27
IL160324A0 (en) 2004-07-25

Similar Documents

Publication Publication Date Title
US8068987B2 (en) Method and system for profiling biological systems
Collins et al. Current challenges and recent developments in mass spectrometry–based metabolomics
Tan et al. Metabolomics study of stepwise hepatocarcinogenesis from the model rats to patients: potential biomarkers effective for small hepatocellular carcinoma diagnosis
Southam et al. A complete workflow for high-resolution spectral-stitching nanoelectrospray direct-infusion mass-spectrometry-based metabolomics and lipidomics
Theodoridis et al. Mass spectrometry‐based holistic analytical approaches for metabolite profiling in systems biology studies
Lindon et al. Metabonomics in pharmaceutical R & D
Milman General principles of identification by mass spectrometry
Kuhl et al. CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets
Peckner et al. Specter: linear deconvolution for targeted analysis of data-independent acquisition mass spectrometry proteomics
Lu et al. LC–MS-based metabonomics analysis
Klassen et al. Metabolomics: definitions and significance in systems biology
Gillet et al. Mass spectrometry applied to bottom-up proteomics: entering the high-throughput era for hypothesis testing
Hill et al. Mass spectral metabonomics beyond elemental formula: chemical database querying by matching experimental with computational fragmentation spectra
Theodoridis et al. Liquid chromatography–mass spectrometry based global metabolite profiling: a review
Barnes et al. Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its future
Tebani et al. Advances in metabolome information retrieval: turning chemistry into biology. Part I: analytical chemistry of the metabolome
Mazzone et al. Metabolite profiles of the serum of patients with non–small cell carcinoma
JP2006522340A (ja) 質量分析データの分析法
Jiang et al. An automated data analysis pipeline for GC− TOF− MS metabonomics studies
Song et al. Technological advances in current metabolomics and its application in tradition Chinese medicine
van der Greef et al. The role of metabolomics in systems biology: a new vision for drug discovery and development
EP1664770B1 (en) Method for determining the impact of a multicomponent synthetic product mixture on the biological profile of a disease within a group of living systems and the development of new combinatorial interventions
Alsaleh et al. Mass spectrometry: a guide for the clinician
Jansen et al. PARAFASCA: ASCA combined with PARAFAC for the analysis of metabolic fingerprinting data
Furlani et al. Liquid chromatography-mass spectrometry for clinical metabolomics: an overview

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued