CA2457432A1 - Method and system for profiling biological systems - Google Patents
Method and system for profiling biological systems Download PDFInfo
- Publication number
- CA2457432A1 CA2457432A1 CA002457432A CA2457432A CA2457432A1 CA 2457432 A1 CA2457432 A1 CA 2457432A1 CA 002457432 A CA002457432 A CA 002457432A CA 2457432 A CA2457432 A CA 2457432A CA 2457432 A1 CA2457432 A1 CA 2457432A1
- Authority
- CA
- Canada
- Prior art keywords
- analysis
- data sets
- correlation
- sets
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioethics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Evolutionary Computation (AREA)
- Artificial Intelligence (AREA)
- Public Health (AREA)
- Software Systems (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Signal Processing (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31214501P | 2001-08-13 | 2001-08-13 | |
| US60/312,145 | 2001-08-13 | ||
| PCT/US2002/025734 WO2003017177A2 (en) | 2001-08-13 | 2002-08-13 | Method and system for profiling biological systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2457432A1 true CA2457432A1 (en) | 2003-02-27 |
Family
ID=23210073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002457432A Abandoned CA2457432A1 (en) | 2001-08-13 | 2002-08-13 | Method and system for profiling biological systems |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8068987B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1425695A2 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2005500543A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2457432A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL160324A0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003017177A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (63)
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| CA2298181C (en) * | 2000-02-02 | 2006-09-19 | Dayan Burke Goodnough | Non-targeted complex sample analysis |
| DE60135549D1 (de) | 2000-06-19 | 2008-10-09 | Correlogic Systems Inc | Heuristisches klassifikationsverfahren |
| CN1484806A (zh) * | 2000-07-18 | 2004-03-24 | �����弪��ϵͳ��˾ | 基于隐含模式用于从生物数据中识别生物状态的方法 |
| WO2003017177A2 (en) | 2001-08-13 | 2003-02-27 | Beyong Genomics, Inc. | Method and system for profiling biological systems |
| TW200407543A (en) * | 2002-07-29 | 2004-05-16 | Correlogic Systems Inc | Quality assurance/quality control for high throughput bioassay process |
| US9740817B1 (en) | 2002-10-18 | 2017-08-22 | Dennis Sunga Fernandez | Apparatus for biological sensing and alerting of pharmaco-genomic mutation |
| WO2004052191A1 (ja) | 2002-12-09 | 2004-06-24 | Ajinomoto Co., Inc. | 生体状態情報処理装置、生体状態情報処理方法、生体状態情報管理システム、プログラム、および、記録媒体 |
| US7457708B2 (en) * | 2003-03-13 | 2008-11-25 | Agilent Technologies Inc | Methods and devices for identifying related ions from chromatographic mass spectral datasets containing overlapping components |
| AU2003901196A0 (en) * | 2003-03-17 | 2003-04-03 | Commonwealth Scientific And Industrial Research Organisation | Analysis method |
| GB0307352D0 (en) | 2003-03-29 | 2003-05-07 | Qinetiq Ltd | Improvements in and relating to the analysis of compounds |
| US20040236603A1 (en) * | 2003-05-22 | 2004-11-25 | Biospect, Inc. | System of analyzing complex mixtures of biological and other fluids to identify biological state information |
| US7425700B2 (en) * | 2003-05-22 | 2008-09-16 | Stults John T | Systems and methods for discovery and analysis of markers |
| WO2004106915A1 (en) * | 2003-05-29 | 2004-12-09 | Waters Investments Limited | Method and device for processing of lc-ms or lc-ms/ms data in metabonomics |
| MXPA06001170A (es) * | 2003-08-01 | 2006-05-15 | Correlogic Systems Inc | Caracteristicas proteomicas de suero de alta resolucion multiples para deteccion de cancer de ovarios. |
| WO2005020125A2 (en) * | 2003-08-20 | 2005-03-03 | Bg Medicine, Inc. | Methods and systems for profiling biological systems |
| US8346482B2 (en) | 2003-08-22 | 2013-01-01 | Fernandez Dennis S | Integrated biosensor and simulation system for diagnosis and therapy |
| EP1512970A1 (en) * | 2003-09-05 | 2005-03-09 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Method for determining the impact of a multicomponent mixture on the biological profile of a disease |
| JP4774534B2 (ja) * | 2003-12-11 | 2011-09-14 | アングーク ファーマシューティカル カンパニー,リミティド | 集中化適応モデル及び遠隔操作サンプルプロセッシングの使用を介した生物学的状態の診断方法 |
| CA2501003C (en) | 2004-04-23 | 2009-05-19 | F. Hoffmann-La Roche Ag | Sample analysis to provide characterization data |
| US20050244973A1 (en) * | 2004-04-29 | 2005-11-03 | Predicant Biosciences, Inc. | Biological patterns for diagnosis and treatment of cancer |
| US8685659B2 (en) | 2005-01-28 | 2014-04-01 | Children's Medical Center Corporation | Method for diagnosis and prognosis of epithelial cancers |
| US20070003996A1 (en) * | 2005-02-09 | 2007-01-04 | Hitt Ben A | Identification of bacteria and spores |
| EP1862797A4 (en) * | 2005-03-16 | 2009-09-16 | Ajinomoto Kk | DEVICE, METHOD, SYSTEM AND PROGRAM FOR EVALUATING BIOLOGICAL STATES, DEVICE, METHOD AND PROGRAM FOR GENERATING AN EVALUATION FUNCTION AND RECORDING MEDIUM |
| WO2006124628A2 (en) * | 2005-05-12 | 2006-11-23 | Correlogic Systems, Inc. | A model for classifying a biological sample in relation to breast cancer based on mass spectral data |
| JP5038311B2 (ja) | 2005-09-12 | 2012-10-03 | フェノメノーム ディスカバリーズ インク | ビタミンe関連代謝産物の測定による、結腸直腸癌及び卵巣癌の診断方法 |
| US20070162992A1 (en) * | 2006-01-09 | 2007-07-12 | Mcgill University | Metabolomic determination in assisted reproductive technology |
| CA2642833A1 (en) | 2006-02-17 | 2007-08-30 | Children's Medical Center Corporation | Free ngal as a biomarker for cancer |
| US7736905B2 (en) | 2006-03-31 | 2010-06-15 | Biodesix, Inc. | Method and system for determining whether a drug will be effective on a patient with a disease |
| WO2007140270A2 (en) * | 2006-05-25 | 2007-12-06 | Vialogy Corp. | Analyzing information gathered using multiple analytical techniques |
| WO2008100941A2 (en) * | 2007-02-12 | 2008-08-21 | Correlogic Systems Inc. | A method for calibrating an analytical instrument |
| EP2538049B1 (en) | 2007-03-30 | 2015-03-18 | Continental Automotive Systems US, Inc. | Reductant delivery unit for selective catalytic reduction |
| AU2008268461B2 (en) | 2007-06-22 | 2015-04-09 | Children's Medical Center Corporation | Methods and uses thereof of prosaposin |
| KR20120087885A (ko) | 2007-06-29 | 2012-08-07 | 안국약품 주식회사 | 난소암의 예측 마커 |
| JP4983451B2 (ja) * | 2007-07-18 | 2012-07-25 | 株式会社島津製作所 | クロマトグラフ質量分析データ処理装置 |
| US20100099135A1 (en) * | 2008-10-22 | 2010-04-22 | Mandy Katz-Jaffe | Methods and assays for assessing the quality of embryos in assisted reproduction technology protocols |
| JP5436446B2 (ja) * | 2008-12-01 | 2014-03-05 | 国立大学法人山口大学 | 薬剤の作用・副作用予測システムとそのプログラム |
| ES2573954T3 (es) | 2008-12-30 | 2016-06-13 | Children's Medical Center Corporation | Método de predicción de apendicitis aguda |
| WO2010079253A2 (es) | 2009-01-09 | 2010-07-15 | Proyecto De Biomedicina Cima, S.L. | Biomarcadores para el diagnóstico de fibrosis |
| AU2010339794B2 (en) | 2009-12-17 | 2016-09-22 | Children's Medical Center Corporation | Saposin-A derived peptides and uses thereof |
| KR101149236B1 (ko) * | 2010-04-09 | 2012-05-25 | 대한민국(농촌진흥청장) | 크로마토그래피?질량분석을 이용한 인삼 연근 판별 방법 |
| EP2583107A2 (en) * | 2010-06-20 | 2013-04-24 | Zora Biosciences OY | Lipidomic biomarkers for identification of high-risk coronary artery disease patients |
| JP2013545439A (ja) | 2010-09-17 | 2013-12-26 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 多能性幹細胞の有用性および安全性の特徴決定を行うための機能的ゲノミクスアッセイ |
| DE102010038014B4 (de) * | 2010-10-06 | 2021-10-07 | Numares Ag | Verwendung spezifischer Substanzen als Marker zur Bestimmung des Risikos einer Nierenabstoßung |
| CN102478563B (zh) * | 2010-11-25 | 2014-08-13 | 中国科学院大连化学物理研究所 | 一种用于研究转基因和非转基因水稻代谢差异的方法 |
| JP2014527036A (ja) | 2011-06-27 | 2014-10-09 | ザ ジャクソン ラボラトリー | 癌および自己免疫疾患の処置のための方法および組成物 |
| US10378060B2 (en) | 2011-10-14 | 2019-08-13 | Dana-Farber Cancer Institute, Inc. | ZNF365/ZFP365 biomarker predictive of anti-cancer response |
| RU2622082C2 (ru) | 2011-11-14 | 2017-06-09 | Нестек С.А. | Анализы и способы выбора режима лечения пациента с депрессией |
| US10736935B2 (en) | 2011-12-22 | 2020-08-11 | Children's Medical Center Corporation | Saposin-A derived peptides and uses thereof |
| MX351313B (es) | 2012-01-05 | 2017-10-10 | Boston Medical Ct Corp | Señalización de slit-robo para diagnosis y tratamiento de enfermedad del riñón. |
| AU2012367247B2 (en) | 2012-01-24 | 2018-04-05 | Cd Diagnostics, Inc. | System for detecting infection in synovial fluid |
| CN103913698B (zh) * | 2014-03-27 | 2016-07-06 | 西北工业大学 | 基于小波分形及核主元特征的开关电流电路故障诊断方法 |
| US11624093B2 (en) | 2014-04-24 | 2023-04-11 | Dana-Farber Cancer Institute, Inc. | Tumor suppressor and oncogene biomarkers predictive of anti-immune checkpoint inhibitor response |
| KR20170020463A (ko) | 2014-06-19 | 2017-02-22 | 메모리얼 슬로안-케터링 캔서 센터 | Ezh2 저해제에의 반응에 대한 바이오마커 |
| WO2016011383A1 (en) | 2014-07-17 | 2016-01-21 | The Trustees Of The University Of Pennsylvania | Methods for using exosomes to monitor transplanted organ status |
| AU2016301231A1 (en) | 2015-08-04 | 2018-02-22 | Cd Diagnostics, Inc. | Methods for detecting adverse local tissue reaction (ALTR) necrosis |
| WO2017147186A1 (en) | 2016-02-22 | 2017-08-31 | Ursure, Inc. | System and method for detecting therapeutic agents to monitor adherence to a treatment regimen |
| CN106022373B (zh) * | 2016-05-18 | 2019-04-23 | 江南大学 | 一种基于广义均值典型相关分析的图像识别方法 |
| CN109187614B (zh) * | 2018-09-27 | 2020-03-06 | 厦门大学 | 基于核磁共振和质谱的代谢组学数据融合方法及其应用 |
| CN117233413A (zh) | 2019-08-05 | 2023-12-15 | 禧尔公司 | 用于样品制备、数据生成和蛋白质冠分析的系统和方法 |
| US12018279B2 (en) | 2019-10-18 | 2024-06-25 | The Trustees Of The University Of Pennsylvania | Micro-engineered models of the human eye and methods of use |
| WO2022086852A2 (en) | 2020-10-19 | 2022-04-28 | Dana-Farber Cancer Institute, Inc. | Germline biomarkers of clinical response and benefit to immune checkpoint inhibitor therapy |
| CA3209638A1 (en) | 2021-02-25 | 2022-09-01 | Lung Therapeutics, Inc. | Biomarkers for the treatment of interstitial lung disease |
| EP4074820A1 (en) | 2021-04-16 | 2022-10-19 | The Trustees of The University of Pennsylvania | Micro-engineered models of the human eye and methods of use |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6194217B1 (en) | 1980-01-14 | 2001-02-27 | Esa, Inc. | Method of diagnosing or categorizing disorders from biochemical profiles |
| US5644503A (en) | 1994-03-28 | 1997-07-01 | Hitachi, Ltd. | Methods and apparatuses for analyzing multichannel chromatogram |
| JP3270290B2 (ja) * | 1994-04-28 | 2002-04-02 | 株式会社日立製作所 | マルチチャンネルクロマトグラムの解析方法及びデータ処理装置 |
| US6031232A (en) | 1995-11-13 | 2000-02-29 | Bio-Rad Laboratories, Inc. | Method for the detection of malignant and premalignant stages of cervical cancer |
| US6699710B1 (en) | 1998-02-25 | 2004-03-02 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor tissue microarrays for rapid molecular profiling |
| US6428956B1 (en) * | 1998-03-02 | 2002-08-06 | Isis Pharmaceuticals, Inc. | Mass spectrometric methods for biomolecular screening |
| AU3367799A (en) | 1998-03-30 | 1999-10-18 | Esa Inc. | Methodology for predicting and/or diagnosing disease |
| CA2362058A1 (en) * | 1999-02-10 | 2000-08-17 | Oxford Natural Products Plc | Process for quality control and standardisation of medicinal plant products |
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| AU2579401A (en) * | 1999-12-17 | 2001-06-25 | Johns Hopkins University, The | Brain protein markers |
| ATE516497T1 (de) | 2000-03-06 | 2011-07-15 | Asterand Acquisition Llc | Screening für funktionshomologien |
| GB0013007D0 (en) | 2000-05-30 | 2000-07-19 | Imperial College | Characterization system and method |
| CN1484806A (zh) | 2000-07-18 | 2004-03-24 | �����弪��ϵͳ��˾ | 基于隐含模式用于从生物数据中识别生物状态的方法 |
| NL1016034C2 (nl) | 2000-08-03 | 2002-02-08 | Tno | Werkwijze en systeem voor het identificeren en kwantificeren van chemische componenten van een te onderzoeken mengsel van materialen. |
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| US20030130798A1 (en) | 2000-11-14 | 2003-07-10 | The Institute For Systems Biology | Multiparameter integration methods for the analysis of biological networks |
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| US7343247B2 (en) | 2001-07-30 | 2008-03-11 | The Institute For Systems Biology | Methods of classifying drug responsiveness using multiparameter analysis |
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| WO2003023366A2 (en) | 2001-09-12 | 2003-03-20 | The State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Method and system for classifying a scenario |
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| EP1481356A1 (en) | 2001-11-21 | 2004-12-01 | Paradigm Genetics Inc. | Methods and systems for analyzing complex biological systems |
| EP1327883A3 (en) | 2002-01-10 | 2003-07-30 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Combined metabolomic, proteomic and transcriptomic analysis from one, single sample and suitable statistical evaluation of data |
| US7623969B2 (en) | 2002-01-31 | 2009-11-24 | The Institute For Systems Biology | Gene discovery for the system assignment of gene function |
| AU2003239409A1 (en) | 2002-05-09 | 2003-11-11 | Surromed, Inc. | Methods for time-alignment of liquid chromatography-mass spectrometry data |
| IN2004DN03762A (cg-RX-API-DMAC7.html) | 2002-06-14 | 2010-01-08 | Pfizer | |
| WO2004044554A2 (en) | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
-
2002
- 2002-08-13 WO PCT/US2002/025734 patent/WO2003017177A2/en not_active Ceased
- 2002-08-13 JP JP2003522011A patent/JP2005500543A/ja active Pending
- 2002-08-13 US US10/218,880 patent/US8068987B2/en not_active Expired - Fee Related
- 2002-08-13 IL IL16032402A patent/IL160324A0/xx unknown
- 2002-08-13 CA CA002457432A patent/CA2457432A1/en not_active Abandoned
- 2002-08-13 EP EP02752828A patent/EP1425695A2/en not_active Ceased
-
2005
- 2005-05-31 US US11/141,253 patent/US20050283320A1/en not_active Abandoned
- 2005-05-31 US US11/141,258 patent/US20050273275A1/en not_active Abandoned
-
2009
- 2009-02-27 JP JP2009047371A patent/JP2009133867A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20050273275A1 (en) | 2005-12-08 |
| US20030134304A1 (en) | 2003-07-17 |
| US20050283320A1 (en) | 2005-12-22 |
| US8068987B2 (en) | 2011-11-29 |
| EP1425695A2 (en) | 2004-06-09 |
| JP2009133867A (ja) | 2009-06-18 |
| WO2003017177A3 (en) | 2004-04-08 |
| JP2005500543A (ja) | 2005-01-06 |
| WO2003017177A2 (en) | 2003-02-27 |
| IL160324A0 (en) | 2004-07-25 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |