CA2453110C - System for the separation of magnetically attractable particles - Google Patents

System for the separation of magnetically attractable particles Download PDF

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Publication number
CA2453110C
CA2453110C CA2453110A CA2453110A CA2453110C CA 2453110 C CA2453110 C CA 2453110C CA 2453110 A CA2453110 A CA 2453110A CA 2453110 A CA2453110 A CA 2453110A CA 2453110 C CA2453110 C CA 2453110C
Authority
CA
Canada
Prior art keywords
microparticles
vessel
magnets
separation
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2453110A
Other languages
English (en)
French (fr)
Other versions
CA2453110A1 (en
Inventor
Hans-Juergen Mueller
Andreas Holzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2453110A1 publication Critical patent/CA2453110A1/en
Application granted granted Critical
Publication of CA2453110C publication Critical patent/CA2453110C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/035—Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Sampling And Sample Adjustment (AREA)
CA2453110A 2001-07-25 2002-07-23 System for the separation of magnetically attractable particles Expired - Fee Related CA2453110C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10136060.6 2001-07-25
DE10136060A DE10136060A1 (de) 2001-07-25 2001-07-25 System zur Separation von magnetisch anziehbaren Partikeln
PCT/EP2002/008174 WO2003009943A1 (de) 2001-07-25 2002-07-23 System zur separation von magnetisch anziehbaren partikeln

Publications (2)

Publication Number Publication Date
CA2453110A1 CA2453110A1 (en) 2003-02-06
CA2453110C true CA2453110C (en) 2010-02-09

Family

ID=7692933

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2453110A Expired - Fee Related CA2453110C (en) 2001-07-25 2002-07-23 System for the separation of magnetically attractable particles

Country Status (8)

Country Link
US (1) US7326350B2 (https=)
EP (1) EP1420888B1 (https=)
JP (1) JP3842784B2 (https=)
AT (1) ATE297255T1 (https=)
CA (1) CA2453110C (https=)
DE (2) DE10136060A1 (https=)
ES (1) ES2242877T3 (https=)
WO (1) WO2003009943A1 (https=)

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WO2003086637A1 (en) 2002-04-12 2003-10-23 Instrumentation Laboratory Company Immunoassay probe
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
US7535329B2 (en) * 2005-04-14 2009-05-19 Makrochem, Ltd. Permanent magnet structure with axial access for spectroscopy applications
US7867765B2 (en) * 2005-12-28 2011-01-11 The General Hospital Corporation Blood cell sorting methods and systems
US8268116B2 (en) 2007-06-14 2012-09-18 Lam Research Corporation Methods of and apparatus for protecting a region of process exclusion adjacent to a region of process performance in a process chamber
US8795609B2 (en) * 2007-02-08 2014-08-05 Biokit, S.A. Magnetic particle washing station
JP2008209330A (ja) * 2007-02-28 2008-09-11 Hitachi High-Technologies Corp 磁気分離器およびそれを用いた分析装置
GB0724404D0 (en) * 2007-05-29 2008-01-30 Invitrogen Dynal As A sample vessel retaining portion
US9199247B2 (en) * 2007-05-29 2015-12-01 Invitrogen Dynal As Magnetic separation rack
JP4586054B2 (ja) * 2007-08-31 2010-11-24 株式会社日立ハイテクノロジーズ 自動分析装置
US8723113B2 (en) * 2008-05-30 2014-05-13 The State of Oregon Acting by and through the State Board of Higher Education of behalf of Oregon State University Radio-frequency-free hybrid electrostatic/magnetostatic cell for transporting, trapping, and dissociating ions in mass spectrometers
US20110177592A1 (en) * 2008-07-11 2011-07-21 Faustman Denise L Magnetic apparatus for blood separation
EP2208531A1 (en) * 2008-12-30 2010-07-21 Atonomics A/S Distribution of particles in capillary channel by application of magnetic field
EP2246349A1 (en) 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases
US20120262260A1 (en) * 2011-04-18 2012-10-18 Exact Sciences Corporation Magnetic microparticle localization device
US10079086B2 (en) * 2012-06-29 2018-09-18 Koninklijke Philips N.V. Processing of bound and unbound magnetic particles
EP2883237B1 (en) 2012-08-16 2020-11-25 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Electromagnetostatic electron-induced dissociation cell
US9803787B2 (en) * 2012-09-14 2017-10-31 The United States Of America, As Represented By The Secretary Of The Navy Magnetically attracted fluid transfer system
KR101367122B1 (ko) * 2012-09-20 2014-02-26 한국원자력연구원 영구자석을 이용한 자기 장치
US20150233932A1 (en) * 2013-02-19 2015-08-20 Ching-Ping Tseng Methods, Systems, and Compositions for Enrichment of Rare Cells
US9387486B2 (en) * 2014-09-30 2016-07-12 Ut-Battelle, Llc High-gradient permanent magnet apparatus and its use in particle collection
JP6472973B2 (ja) 2014-10-24 2019-02-20 日本電子株式会社 自動分析装置及び分離洗浄方法
CZ2015141A3 (cs) * 2015-02-26 2016-09-14 Univerzita PalackĂ©ho v Olomouci Zařízení pro magnetickou separaci feromagnetických částic, sada pro magnetickou separaci částic, způsob separace magnetických částic z roztoku a použití zařízení nebo sady pro magnetickou separaci částic
EP3400308B1 (en) * 2016-01-05 2020-02-19 Roche Diagnostics GmbH Successive capture of nucleic acid by magnetic glass particles
US11408543B2 (en) 2018-02-28 2022-08-09 Kohler Co. Articulating faucet
US10890277B2 (en) 2018-02-28 2021-01-12 Kohler Co. Articulating faucet with progressive magnetic joint
US11125365B2 (en) 2018-02-28 2021-09-21 Kohler Co. Magnetic joint
US11214946B2 (en) 2018-06-04 2022-01-04 Kohler Co. Articulating faucet
CN110552401B (zh) 2018-06-04 2021-09-03 科勒公司 铰接水龙头
WO2024095741A1 (ja) * 2022-10-31 2024-05-10 富士フイルム株式会社 集磁ユニット及び検査装置
JPWO2024095740A1 (https=) * 2022-10-31 2024-05-10

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6253714A (ja) * 1985-08-30 1987-03-09 Kamata Bio Eng Kk 流体の磁化浄化装置
JPS6295371A (ja) 1985-10-22 1987-05-01 Agency Of Ind Science & Technol 粉末状吸湿架橋性ホツトメルト接着剤の製造方法
EP0479448A3 (en) 1990-10-02 1992-12-23 Beckman Instruments, Inc. Magnetic separation device
US5897783A (en) * 1992-09-24 1999-04-27 Amersham International Plc Magnetic separation method
US5599501A (en) * 1994-11-10 1997-02-04 Ciba Corning Diagnostics Corp. Incubation chamber
AU4927496A (en) * 1995-02-21 1996-09-11 Iqbal W. Siddiqi Apparatus and method for mixing and separation employing magnetic particles
US5888835A (en) * 1996-05-10 1999-03-30 Chiron Diagnostics Corporation Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology
US6451207B1 (en) * 1997-06-04 2002-09-17 Dexter Magnetic Technologies, Inc. Magnetic cell separation device
WO2001035759A1 (en) * 1999-11-17 2001-05-25 University Of Virginia Patent Foundation Sperm cell selection system

Also Published As

Publication number Publication date
US7326350B2 (en) 2008-02-05
JP2004535591A (ja) 2004-11-25
ES2242877T3 (es) 2005-11-16
WO2003009943A8 (de) 2005-03-03
CA2453110A1 (en) 2003-02-06
DE10136060A1 (de) 2003-02-13
ATE297255T1 (de) 2005-06-15
EP1420888A1 (de) 2004-05-26
JP3842784B2 (ja) 2006-11-08
WO2003009943A1 (de) 2003-02-06
EP1420888B1 (de) 2005-06-08
DE50203361D1 (de) 2005-07-14
US20040265903A1 (en) 2004-12-30

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Effective date: 20170724