CA2451394C - Il-4 receptor sequence variation associated with type 1 diabetes - Google Patents

Il-4 receptor sequence variation associated with type 1 diabetes Download PDF

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Publication number
CA2451394C
CA2451394C CA002451394A CA2451394A CA2451394C CA 2451394 C CA2451394 C CA 2451394C CA 002451394 A CA002451394 A CA 002451394A CA 2451394 A CA2451394 A CA 2451394A CA 2451394 C CA2451394 C CA 2451394C
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CA
Canada
Prior art keywords
allele
sequence
il4r
artificial sequence
diabetes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002451394A
Other languages
English (en)
French (fr)
Other versions
CA2451394A1 (en
Inventor
Daniel B. Mirel
Henry A Erlich
Teodorica L. Bugawan
Janelle A. Noble
Ana Maria Valdes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2451394A1 publication Critical patent/CA2451394A1/en
Application granted granted Critical
Publication of CA2451394C publication Critical patent/CA2451394C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002451394A 2001-07-20 2002-07-17 Il-4 receptor sequence variation associated with type 1 diabetes Expired - Fee Related CA2451394C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30691201P 2001-07-20 2001-07-20
US60/306,912 2001-07-20
PCT/EP2002/007956 WO2003010335A2 (en) 2001-07-20 2002-07-17 Il-4 receptor sequence variation associated with type 1 diabetes

Publications (2)

Publication Number Publication Date
CA2451394A1 CA2451394A1 (en) 2003-02-06
CA2451394C true CA2451394C (en) 2010-02-02

Family

ID=23187422

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002451394A Expired - Fee Related CA2451394C (en) 2001-07-20 2002-07-17 Il-4 receptor sequence variation associated with type 1 diabetes

Country Status (7)

Country Link
US (1) US20030152951A1 (enExample)
EP (1) EP1412531B1 (enExample)
JP (1) JP2004535822A (enExample)
AT (1) ATE393238T1 (enExample)
CA (1) CA2451394C (enExample)
DE (1) DE60226244T2 (enExample)
WO (1) WO2003010335A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7205106B1 (en) * 2001-07-20 2007-04-17 Roche Molecular Systems, Inc. Association of polymorphisms in IL4-related genes with autoimmune disease
WO2006051886A1 (ja) * 2004-11-12 2006-05-18 Osaka University 組織破壊によって機能障害を来たす自己免疫疾患の重症化の可能性を予測する方法
CA2625446A1 (en) * 2005-10-13 2007-04-19 Friedrich-Alexander-Universitaet Erlangen-Nuernberg Means and methods for the prediction of joint destruction
GB0523276D0 (en) 2005-11-15 2005-12-21 London Bridge Fertility Chromosomal analysis by molecular karyotyping
WO2009140679A2 (en) * 2008-05-16 2009-11-19 The Children's Hospital Of Philadelphia Genetic alterations on chromosomes 21q, 6q and 15q and methods of use thereof for the diagnosis and treatment of type i diabetes
JP7566322B2 (ja) * 2021-04-14 2024-10-15 国立大学法人広島大学 制御装置、制御プログラムおよび制御方法
JP2024546366A (ja) * 2021-10-27 2024-12-20 マース インコーポレーテッド ペットの親類検索システムおよび方法

Also Published As

Publication number Publication date
ATE393238T1 (de) 2008-05-15
CA2451394A1 (en) 2003-02-06
WO2003010335A3 (en) 2003-10-30
WO2003010335A2 (en) 2003-02-06
DE60226244D1 (de) 2008-06-05
US20030152951A1 (en) 2003-08-14
EP1412531A2 (en) 2004-04-28
JP2004535822A (ja) 2004-12-02
DE60226244T2 (de) 2009-06-25
EP1412531B1 (en) 2008-04-23

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20140717