CA2439478C - Carbamate compounds for use in preventing or treating movement disorders - Google Patents

Carbamate compounds for use in preventing or treating movement disorders Download PDF

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Publication number
CA2439478C
CA2439478C CA2439478A CA2439478A CA2439478C CA 2439478 C CA2439478 C CA 2439478C CA 2439478 A CA2439478 A CA 2439478A CA 2439478 A CA2439478 A CA 2439478A CA 2439478 C CA2439478 C CA 2439478C
Authority
CA
Canada
Prior art keywords
formula
group
tremor
movement disorders
enantiomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2439478A
Other languages
English (en)
French (fr)
Other versions
CA2439478A1 (en
Inventor
Carlos R. Plata-Salaman
Boyu Zhao
Roy E. Twyman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Biopharmaceuticals Co Ltd
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of CA2439478A1 publication Critical patent/CA2439478A1/en
Application granted granted Critical
Publication of CA2439478C publication Critical patent/CA2439478C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2439478A 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating movement disorders Expired - Fee Related CA2439478C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27168301P 2001-02-27 2001-02-27
US60/271,683 2001-02-27
US10/081,501 US6589985B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating movement disorders
PCT/US2002/005542 WO2002067926A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating movement disorders
US10/081,501 2002-02-21

Publications (2)

Publication Number Publication Date
CA2439478A1 CA2439478A1 (en) 2002-09-06
CA2439478C true CA2439478C (en) 2010-05-18

Family

ID=26765643

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2439478A Expired - Fee Related CA2439478C (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating movement disorders

Country Status (27)

Country Link
US (1) US6589985B2 (https=)
EP (1) EP1411917B1 (https=)
JP (1) JP2004527492A (https=)
KR (1) KR100858232B1 (https=)
CN (1) CN1262272C (https=)
AR (1) AR033426A1 (https=)
AT (1) ATE369130T1 (https=)
AU (1) AU2002247204B2 (https=)
BR (1) BR0207831A (https=)
CA (1) CA2439478C (https=)
CY (1) CY1106924T1 (https=)
CZ (1) CZ20032299A3 (https=)
DE (1) DE60221670T2 (https=)
DK (1) DK1411917T3 (https=)
ES (1) ES2291454T3 (https=)
HU (1) HUP0303344A3 (https=)
IL (2) IL157592A0 (https=)
MX (1) MXPA03007719A (https=)
MY (1) MY157373A (https=)
NO (1) NO20033803L (https=)
NZ (1) NZ551954A (https=)
PL (1) PL364679A1 (https=)
PT (1) PT1411917E (https=)
RS (1) RS50676B (https=)
RU (1) RU2294739C2 (https=)
TW (1) TWI331524B (https=)
WO (1) WO2002067926A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7349301A (en) * 2000-07-21 2002-02-05 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
PL364680A1 (en) * 2001-02-27 2004-12-13 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neurodegenerative disorders
PL368164A1 (en) 2001-07-16 2005-03-21 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
ES2435403T3 (es) 2005-06-08 2013-12-19 Sk Biopharmaceuticals Co., Ltd. Tratamiento de trastornos del sueño y vigilia
PE20070325A1 (es) * 2005-06-29 2007-05-12 Alza Corp Formas de dosificacion oral que comprenden compuestos derivados de carbamato
AU2005335241B9 (en) * 2005-07-26 2012-12-20 Sk Biopharmaceuticals Co., Ltd. Methods for treating substance-related disorders
MX2009004798A (es) * 2006-10-31 2009-08-12 Janssen Pharmaceutica Nv Tratamiento de los trastornos generalizados del desarrollo.
MX350745B (es) 2009-11-06 2017-09-14 Sk Biopharmaceuticals Co Ltd * El uso de un compuesto de carbamoilo para el tratamiento del sindrome de fibromialgia.
US8895609B2 (en) 2009-11-06 2014-11-25 Sk Biopharmaceuticals Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
US8623913B2 (en) * 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
US9566261B2 (en) 2013-03-12 2017-02-14 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a memory loss-related disease comprising the same
EP2968210B1 (en) * 2013-03-12 2024-09-11 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compounds for use in preventing or treating pediatric epilesy
ES3059582T3 (en) 2016-02-29 2026-03-23 Bio Pharm Solutions Co Ltd Sulfamate derivative compounds, processes for preparing them and their uses
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
MX391363B (es) * 2016-12-14 2025-03-21 Sk Biopharmaceuticals Co Ltd Uso de compuesto de carbamato para prevenir, aliviar o tratar temblores o el sindrome de temblor.
AU2018278332B2 (en) 2017-06-02 2022-05-19 Jazz Pharmaceuticals Ireland Limited Methods and compositions for treating excessive sleepiness
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
JP2023539291A (ja) * 2020-08-31 2023-09-13 バイオ-ファーム ソリューションズ カンパニー リミテッド 神経変性疾患の予防又は治療用フェニルアルキルカルバメート化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
IL157592A (en) 2009-12-24
WO2002067926A1 (en) 2002-09-06
YU67703A (sh) 2006-08-17
AR033426A1 (es) 2003-12-17
HK1067305A1 (en) 2005-04-08
CN1262272C (zh) 2006-07-05
EP1411917B1 (en) 2007-08-08
KR100858232B1 (ko) 2008-09-12
NO20033803L (no) 2003-10-10
ES2291454T3 (es) 2008-03-01
BR0207831A (pt) 2004-06-22
RS50676B (sr) 2010-06-30
CY1106924T1 (el) 2012-09-26
PL364679A1 (en) 2004-12-13
IL157592A0 (en) 2004-03-28
KR20030074847A (ko) 2003-09-19
DK1411917T3 (da) 2007-09-24
ATE369130T1 (de) 2007-08-15
US20020151585A1 (en) 2002-10-17
NO20033803D0 (no) 2003-08-26
HUP0303344A3 (en) 2012-07-30
CN1505508A (zh) 2004-06-16
MXPA03007719A (es) 2004-11-12
PT1411917E (pt) 2007-09-17
HUP0303344A2 (hu) 2004-01-28
US6589985B2 (en) 2003-07-08
DE60221670T2 (de) 2008-04-30
EP1411917A1 (en) 2004-04-28
CZ20032299A3 (cs) 2004-08-18
CA2439478A1 (en) 2002-09-06
JP2004527492A (ja) 2004-09-09
DE60221670D1 (de) 2007-09-20
AU2002247204B2 (en) 2006-08-24
RU2294739C2 (ru) 2007-03-10
NZ551954A (en) 2008-07-31
TWI331524B (en) 2010-10-11
MY157373A (en) 2016-06-15
RU2003128985A (ru) 2005-03-10

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CA2439478C (en) Carbamate compounds for use in preventing or treating movement disorders
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AU2002242226A1 (en) Carbamate compounds for use in preventing or treating bipolar disorder
HK1067305B (en) Carbamate compounds for use in preventing or treating movement disorders
AU2002354909B2 (en) Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
AU2002255580B2 (en) Carbamate compounds for use in preventing or treating bipolar disorder
AU2002354909A1 (en) Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
HK1063288B (en) Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
AU2002255580A1 (en) Carbamate compounds for use in preventing or treating bipolar disorder
ZA200401155B (en) Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain.

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130221