CA2439478C - Carbamate compounds for use in preventing or treating movement disorders - Google Patents

Carbamate compounds for use in preventing or treating movement disorders Download PDF

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Publication number
CA2439478C
CA2439478C CA2439478A CA2439478A CA2439478C CA 2439478 C CA2439478 C CA 2439478C CA 2439478 A CA2439478 A CA 2439478A CA 2439478 A CA2439478 A CA 2439478A CA 2439478 C CA2439478 C CA 2439478C
Authority
CA
Canada
Prior art keywords
formula
group
tremor
movement disorders
enantiomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2439478A
Other languages
English (en)
French (fr)
Other versions
CA2439478A1 (en
Inventor
Carlos R. Plata-Salaman
Boyu Zhao
Roy E. Twyman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Biopharmaceuticals Co Ltd
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of CA2439478A1 publication Critical patent/CA2439478A1/en
Application granted granted Critical
Publication of CA2439478C publication Critical patent/CA2439478C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2439478A 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating movement disorders Expired - Fee Related CA2439478C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27168301P 2001-02-27 2001-02-27
US60/271,683 2001-02-27
US10/081,501 2002-02-21
US10/081,501 US6589985B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating movement disorders
PCT/US2002/005542 WO2002067926A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating movement disorders

Publications (2)

Publication Number Publication Date
CA2439478A1 CA2439478A1 (en) 2002-09-06
CA2439478C true CA2439478C (en) 2010-05-18

Family

ID=26765643

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2439478A Expired - Fee Related CA2439478C (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating movement disorders

Country Status (27)

Country Link
US (1) US6589985B2 (https=)
EP (1) EP1411917B1 (https=)
JP (1) JP2004527492A (https=)
KR (1) KR100858232B1 (https=)
CN (1) CN1262272C (https=)
AR (1) AR033426A1 (https=)
AT (1) ATE369130T1 (https=)
AU (1) AU2002247204B2 (https=)
BR (1) BR0207831A (https=)
CA (1) CA2439478C (https=)
CY (1) CY1106924T1 (https=)
CZ (1) CZ20032299A3 (https=)
DE (1) DE60221670T2 (https=)
DK (1) DK1411917T3 (https=)
ES (1) ES2291454T3 (https=)
HU (1) HUP0303344A3 (https=)
IL (2) IL157592A0 (https=)
MX (1) MXPA03007719A (https=)
MY (1) MY157373A (https=)
NO (1) NO20033803L (https=)
NZ (1) NZ551954A (https=)
PL (1) PL364679A1 (https=)
PT (1) PT1411917E (https=)
RS (1) RS50676B (https=)
RU (1) RU2294739C2 (https=)
TW (1) TWI331524B (https=)
WO (1) WO2002067926A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE267629T1 (de) * 2000-07-21 2004-06-15 Ortho Mcneil Pharm Inc Verwendung von carbamat verbindungen zur vorbeugung oder behandlung von neuropathischen- , cluster- und migräneartigen kopfschmerzen
EP1383489B1 (en) * 2001-02-27 2007-05-09 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neurodegenerative disorders
ATE435014T1 (de) 2001-07-16 2009-07-15 Ortho Mcneil Pharm Inc Carbamate verbindungen zur vorbeugung oder behandlung von neuropathischen schmerzen
EP1890684B1 (en) 2005-06-08 2013-08-14 SK Biopharmaceuticals Co., Ltd. Treatment of sleep-wake disorders
PE20070325A1 (es) * 2005-06-29 2007-05-12 Alza Corp Formas de dosificacion oral que comprenden compuestos derivados de carbamato
ES2385087T3 (es) * 2005-07-26 2012-07-18 Sk Biopharmaceuticals Co., Ltd Procedimientos para tratar trastornos relacionados con sustancias
BRPI0718323A2 (pt) * 2006-10-31 2013-11-26 Janssen Pharmaceutica Nv Tratamento de transtornos invasivos do desenvolvimento.
EP2496227B1 (en) 2009-11-06 2019-05-22 SK Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
BR112012010670A2 (pt) 2009-11-06 2016-04-12 Sk Biopharmaceuticals Co Ltd métodos para tratamento de distúrbio de défict de atenção/hiperatividade
US8623913B2 (en) * 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CN105189451A (zh) 2013-03-12 2015-12-23 比皮艾思药物研发有限公司 氨基甲酸苯酯化合物和包含该化合物的用于预防或治疗神经性毒气引起的疾病的组合物
CN109939092B (zh) 2013-03-12 2022-03-22 比皮艾思药物研发有限公司 用于预防或治疗小儿癫痫和癫痫相关综合征的苯基氨基甲酸酯化合物
WO2017150903A1 (en) 2016-02-29 2017-09-08 Bio-Pharm Solutions Co., Ltd. Sulfamate derivative compounds, processes for preparing them and their uses
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
US11033531B2 (en) * 2016-12-14 2021-06-15 Sk Biopharmaceuticals Co., Ltd. Use of carbamate compound for preventing, alleviating, or treating tremors or tremor syndrome
BR112019025286A2 (pt) 2017-06-02 2020-06-23 Jazz Pharmaceuticals Ireland Limited Métodos e composições para tratamento de sonolência excessiva
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
KR20230044274A (ko) * 2020-08-31 2023-04-03 (주)바이오팜솔루션즈 신경퇴행성 질환의 예방 또는 치료용 페닐 알킬 카바메이트 화합물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3265728A (en) 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
ATE369130T1 (de) 2007-08-15
CZ20032299A3 (cs) 2004-08-18
TWI331524B (en) 2010-10-11
EP1411917A1 (en) 2004-04-28
DE60221670D1 (de) 2007-09-20
AU2002247204B2 (en) 2006-08-24
CN1505508A (zh) 2004-06-16
US6589985B2 (en) 2003-07-08
DK1411917T3 (da) 2007-09-24
YU67703A (sh) 2006-08-17
MXPA03007719A (es) 2004-11-12
KR100858232B1 (ko) 2008-09-12
HK1067305A1 (en) 2005-04-08
BR0207831A (pt) 2004-06-22
AR033426A1 (es) 2003-12-17
CY1106924T1 (el) 2012-09-26
NO20033803D0 (no) 2003-08-26
HUP0303344A2 (hu) 2004-01-28
CA2439478A1 (en) 2002-09-06
PT1411917E (pt) 2007-09-17
HUP0303344A3 (en) 2012-07-30
ES2291454T3 (es) 2008-03-01
DE60221670T2 (de) 2008-04-30
CN1262272C (zh) 2006-07-05
RS50676B (sr) 2010-06-30
NO20033803L (no) 2003-10-10
JP2004527492A (ja) 2004-09-09
NZ551954A (en) 2008-07-31
MY157373A (en) 2016-06-15
US20020151585A1 (en) 2002-10-17
PL364679A1 (en) 2004-12-13
IL157592A0 (en) 2004-03-28
WO2002067926A1 (en) 2002-09-06
IL157592A (en) 2009-12-24
KR20030074847A (ko) 2003-09-19
RU2294739C2 (ru) 2007-03-10
EP1411917B1 (en) 2007-08-08
RU2003128985A (ru) 2005-03-10

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20130221