CA2430281C - Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence - Google Patents
Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence Download PDFInfo
- Publication number
- CA2430281C CA2430281C CA002430281A CA2430281A CA2430281C CA 2430281 C CA2430281 C CA 2430281C CA 002430281 A CA002430281 A CA 002430281A CA 2430281 A CA2430281 A CA 2430281A CA 2430281 C CA2430281 C CA 2430281C
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- Prior art keywords
- compound
- amount
- present
- mixture
- tilidine
- Prior art date
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- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
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- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10059415.8 | 2000-11-30 | ||
| DE10059415A DE10059415A1 (de) | 2000-11-30 | 2000-11-30 | Verwendung von schwachen Opioiden und gemischten Opioidagonisten/-antagonisten zur Therapie der Harninkontinenz |
| PCT/EP2001/013911 WO2002043713A2 (de) | 2000-11-30 | 2001-11-28 | Verwendung von schwachen opioiden und gemischten opioidagonisten / -antagonisten zur therapie der harninkontinenz |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2430281A1 CA2430281A1 (en) | 2002-06-06 |
| CA2430281C true CA2430281C (en) | 2009-08-25 |
Family
ID=7665212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002430281A Expired - Fee Related CA2430281C (en) | 2000-11-30 | 2001-11-28 | Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7008939B2 (https=) |
| EP (1) | EP1337254B1 (https=) |
| JP (1) | JP2004527465A (https=) |
| AT (1) | ATE287265T1 (https=) |
| AU (2) | AU2002220736B2 (https=) |
| CA (1) | CA2430281C (https=) |
| DE (2) | DE10059415A1 (https=) |
| ES (1) | ES2234933T3 (https=) |
| HU (1) | HUP0303285A3 (https=) |
| MX (1) | MXPA03004713A (https=) |
| NZ (1) | NZ526604A (https=) |
| PL (1) | PL204246B1 (https=) |
| PT (1) | PT1337254E (https=) |
| WO (1) | WO2002043713A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8476280B2 (en) | 2002-05-09 | 2013-07-02 | Versi Group, Llc | Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists |
| US7964315B2 (en) * | 2003-09-12 | 2011-06-21 | Bdf Ip Holdings Ltd. | Shutdown methods and designs for fuel cell stacks |
| JP4902883B2 (ja) * | 2005-03-11 | 2012-03-21 | ビーディーエフ アイピー ホールディングス リミテッド | 燃料電池スタックのシャットダウン方法および設計 |
| TW200800223A (en) * | 2005-12-21 | 2008-01-01 | Shire Pharmaceuticals Inc | Transdermal delivery of meptazinol |
| US8748448B2 (en) | 2007-10-18 | 2014-06-10 | Aiko Biotechnology | Combination analgesic employing opioid agonist and neutral antagonist |
| EP2214672B1 (en) * | 2007-10-18 | 2012-10-17 | Aiko Biotechnology | Combination analgesic employing opioid and neutral antagonist |
| CN102836122A (zh) * | 2011-06-24 | 2012-12-26 | 扬子江药业集团四川海蓉药业有限公司 | 含有盐酸美普他酚的组合物注射液及其制备方法 |
| CN109646397A (zh) * | 2015-02-13 | 2019-04-19 | 成都苑东生物制药股份有限公司 | 一种盐酸美普他酚注射液药物组合物及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5354863A (en) * | 1992-01-21 | 1994-10-11 | G. D. Searle & Co. | Opioid agonist compounds |
| GB9202238D0 (en) * | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| USRE36547E (en) * | 1992-09-21 | 2000-02-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists |
| US6159501A (en) * | 1996-03-08 | 2000-12-12 | Nycomed Danmark A/S | Modified release multiple-units dosage composition for release of opioid compounds |
| US5859043A (en) * | 1996-06-11 | 1999-01-12 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Method for maintaining kidney function during surgery or severe trauma under general anesthesia |
| EP1005861B1 (en) * | 1997-04-11 | 2005-06-29 | Nippon Shinyaku Co., Ltd. | Remedies for frequent urination and urinary incontinence |
| US5840696A (en) * | 1997-09-11 | 1998-11-24 | Lippton; Howard | Diuretic and antinatriuretic responses produced by the endogenous opioid-like peptide, nociceptin (orphanin FQ) |
| US6274591B1 (en) * | 1997-11-03 | 2001-08-14 | Joseph F. Foss | Use of methylnaltrexone and related compounds |
| ATE210983T1 (de) * | 1997-11-03 | 2002-01-15 | Stada Arzneimittel Ag | Stabilisiertes kombinationsarzneimittel enthaltend naloxone und ein opiatanalgetikum |
| DE19947747A1 (de) * | 1999-10-05 | 2001-04-12 | Gruenenthal Gmbh | Verwendung von (+)-Tramadol, O-Demethyltramadol bzw. (+)-O-Demethyltramadol zur Therapie der Harninkontinenz |
| US8410129B2 (en) * | 2002-02-15 | 2013-04-02 | Howard Brooks-Korn | Treatment for paresis/paralysis |
-
2000
- 2000-11-30 DE DE10059415A patent/DE10059415A1/de not_active Withdrawn
-
2001
- 2001-11-28 CA CA002430281A patent/CA2430281C/en not_active Expired - Fee Related
- 2001-11-28 AT AT01998335T patent/ATE287265T1/de active
- 2001-11-28 HU HU0303285A patent/HUP0303285A3/hu unknown
- 2001-11-28 DE DE50105150T patent/DE50105150D1/de not_active Expired - Lifetime
- 2001-11-28 EP EP01998335A patent/EP1337254B1/de not_active Expired - Lifetime
- 2001-11-28 NZ NZ526604A patent/NZ526604A/en not_active IP Right Cessation
- 2001-11-28 AU AU2002220736A patent/AU2002220736B2/en not_active Ceased
- 2001-11-28 PT PT01998335T patent/PT1337254E/pt unknown
- 2001-11-28 JP JP2002545684A patent/JP2004527465A/ja active Pending
- 2001-11-28 WO PCT/EP2001/013911 patent/WO2002043713A2/de not_active Ceased
- 2001-11-28 PL PL363677A patent/PL204246B1/pl unknown
- 2001-11-28 ES ES01998335T patent/ES2234933T3/es not_active Expired - Lifetime
- 2001-11-28 AU AU2073602A patent/AU2073602A/xx active Pending
- 2001-11-28 MX MXPA03004713A patent/MXPA03004713A/es active IP Right Grant
-
2003
- 2003-05-30 US US10/448,322 patent/US7008939B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0303285A3 (en) | 2005-05-30 |
| PL204246B1 (pl) | 2009-12-31 |
| DE50105150D1 (de) | 2005-02-24 |
| AU2002220736B2 (en) | 2006-04-06 |
| JP2004527465A (ja) | 2004-09-09 |
| AU2073602A (en) | 2002-06-11 |
| WO2002043713A2 (de) | 2002-06-06 |
| US7008939B2 (en) | 2006-03-07 |
| WO2002043713A3 (de) | 2002-10-31 |
| ATE287265T1 (de) | 2005-02-15 |
| ES2234933T3 (es) | 2005-07-01 |
| HUP0303285A2 (hu) | 2004-01-28 |
| CA2430281A1 (en) | 2002-06-06 |
| EP1337254A2 (de) | 2003-08-27 |
| PT1337254E (pt) | 2005-05-31 |
| NZ526604A (en) | 2005-04-29 |
| EP1337254B1 (de) | 2005-01-19 |
| DE10059415A1 (de) | 2002-06-06 |
| PL363677A1 (en) | 2004-11-29 |
| MXPA03004713A (es) | 2003-08-19 |
| US20040029905A1 (en) | 2004-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20161128 |