CA2426738A1 - Genes streptococciques - Google Patents

Genes streptococciques Download PDF

Info

Publication number
CA2426738A1
CA2426738A1 CA002426738A CA2426738A CA2426738A1 CA 2426738 A1 CA2426738 A1 CA 2426738A1 CA 002426738 A CA002426738 A CA 002426738A CA 2426738 A CA2426738 A CA 2426738A CA 2426738 A1 CA2426738 A1 CA 2426738A1
Authority
CA
Canada
Prior art keywords
leu
glu
ser
ile
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002426738A
Other languages
English (en)
Inventor
David William Holden
Jeremy Stuart Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ip2ipo Innovations Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0026231A external-priority patent/GB0026231D0/en
Priority claimed from GB0028345A external-priority patent/GB0028345D0/en
Priority claimed from GB0102666A external-priority patent/GB0102666D0/en
Application filed by Individual filed Critical Individual
Publication of CA2426738A1 publication Critical patent/CA2426738A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des peptides dérivés de S.pneumoniae, identifiés comme déterminants de la virulence et qui peuvent présenter une grande utilité dans la préparation de vaccins pour le traitement de l'infection. Ces peptides peuvent être utilisés comme antigènes ou dans la préparation de micro-organismes atténués prévus pour constituer des vaccins vivants administrés par voie orale.
CA002426738A 2000-10-26 2001-10-26 Genes streptococciques Abandoned CA2426738A1 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0026231.1 2000-10-26
GB0026231A GB0026231D0 (en) 2000-10-26 2000-10-26 Streptococcal genes
GB0028345A GB0028345D0 (en) 2000-11-21 2000-11-21 Streptococcal genes
GB0028345.7 2000-11-21
GB0102666A GB0102666D0 (en) 2001-02-02 2001-02-02 Streptococcal Genes
GB0102666.5 2001-02-02
US28811801P 2001-05-02 2001-05-02
US60/288,118 2001-05-02
PCT/GB2001/004749 WO2002034773A2 (fr) 2000-10-26 2001-10-26 Genes streptococciques

Publications (1)

Publication Number Publication Date
CA2426738A1 true CA2426738A1 (fr) 2002-05-02

Family

ID=27447899

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002426738A Abandoned CA2426738A1 (fr) 2000-10-26 2001-10-26 Genes streptococciques

Country Status (4)

Country Link
EP (1) EP1330473A2 (fr)
AU (1) AU2001295795A1 (fr)
CA (1) CA2426738A1 (fr)
WO (1) WO2002034773A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0208499D0 (en) * 2002-04-12 2002-05-22 Microscience Ltd Streptococcal genes
WO2005026203A2 (fr) * 2003-09-18 2005-03-24 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Promoteurs d'adn et vaccins contre l'anthrax
US8729013B2 (en) 2004-08-26 2014-05-20 The University Of Western Ontario Methods of inhibiting staphylobactin-mediated iron uptake in S. aureus
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
PL2268618T3 (pl) 2008-03-03 2015-11-30 Novartis Ag Związki i kompozycje jako modulatory aktywności receptorów TLR
CN102317439B (zh) * 2009-02-20 2015-11-25 澳大利亚家禽Crc有限公司 减毒活疫苗
JP5867952B2 (ja) 2009-06-10 2016-02-24 ノバルティス アーゲー ベンゾナフチリジン含有ワクチン
BR112012004806B8 (pt) 2009-09-02 2022-10-04 Novartis Ag composições imunogênicas que incluem moduladores da atividade de tlr, método para aumento da eficácia da referida composição e uso
TWI445708B (zh) 2009-09-02 2014-07-21 Irm Llc 作為tlr活性調節劑之化合物及組合物
WO2011057148A1 (fr) 2009-11-05 2011-05-12 Irm Llc Composés et compositions permettant de moduler l'activité des tlr-7
AU2010339921B2 (en) 2009-12-15 2016-08-11 Glaxosmithkline Biologicals S.A. Homogeneous suspension of immunopotentiating compounds and uses thereof
EA031379B1 (ru) 2010-03-23 2018-12-28 Новартис Аг Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний
EP2822586A1 (fr) 2012-03-07 2015-01-14 Novartis AG Formulations contenant un adjuvant d'antigènes de streptococcus pneumoniae
EP2950819B1 (fr) 2013-02-01 2018-03-28 GlaxoSmithKline Biologicals SA Administration intradermique de compositions immunologiques comprenant des agonistes des récepteurs de type toll
US11098349B2 (en) * 2015-11-04 2021-08-24 The Translational Genomics Research Institute Systems and methods of diagnosing and characterizing infections
EA202091931A1 (ru) 2018-02-12 2020-11-05 Иниммьюн Корпорейшн ЛИГАНДЫ Toll-ПОДОБНЫХ РЕЦЕПТОРОВ
KR20230098825A (ko) 2020-11-04 2023-07-04 엘리고 바이오사이언스 씨. 아크네스 개체군에게 dna 페이로드의 원위치 전달을 위한 파지-유래 입자
GB2600962A (en) * 2020-11-12 2022-05-18 Ucl Business Plc Live attenuated strain of Streptococcus pneumoniae and pharmaceutical compositions comprising a live attenuated strain of S. pneumoniae

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5434065A (en) * 1993-05-06 1995-07-18 President And Fellows Of Harvard College In vivo selection of microbial virulence genes
US6346392B1 (en) * 1996-11-27 2002-02-12 Smithkline Beecham Corporation Polynucleotides encoding a novel glutamine transport ATP-binding protein
WO1998006734A1 (fr) * 1996-08-16 1998-02-19 Smithkline Beecham Corporation Nouveaux polynucleotides et polypeptides procaryotes et leurs utilisations
CA2269663A1 (fr) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Antigenes et vaccins actifs contre streptococcus pneumoniae

Also Published As

Publication number Publication date
EP1330473A2 (fr) 2003-07-30
WO2002034773A2 (fr) 2002-05-02
WO2002034773A3 (fr) 2003-03-13
AU2001295795A1 (en) 2002-05-06

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued