CA2422530A1 - Enzymes humaines metabolisant les medicaments - Google Patents

Enzymes humaines metabolisant les medicaments Download PDF

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Publication number
CA2422530A1
CA2422530A1 CA002422530A CA2422530A CA2422530A1 CA 2422530 A1 CA2422530 A1 CA 2422530A1 CA 002422530 A CA002422530 A CA 002422530A CA 2422530 A CA2422530 A CA 2422530A CA 2422530 A1 CA2422530 A1 CA 2422530A1
Authority
CA
Canada
Prior art keywords
polynucleotide
polypeptide
seq
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002422530A
Other languages
English (en)
Inventor
Yalda Azimzai
Mariah R. Baughin
Mark L. Borowsky
Li Ding
Brendan M. Duggan
Vicki S. Elliott
Ameena R. Gandhi
Jennifer A. Griffin
April J. A. Hafalia
Craig H. Ison
Farrah A. Khan
Preeti Lal
Ernestine A. Lee
Dyung Aina M. Lu
Danniel B. Nguyen
Chandra Arvizu
Jennifer L. Policky
Jayalaxmi Ramkumar
Huijun Z. Ring
Madhu S. Sanjanwala
Y. Tom Tang
Catherine M. Tribouley
Narinder K. Chawla
Roderick T. Walsh
Bridget A. Warren
Yuming Xu
Junming Yang
Monique G. Yao
Henry Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of CA2422530A1 publication Critical patent/CA2422530A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/80—Cytochromes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne des enzymes humaines métabolisant les médicaments ou (DME) et des polynucléotides identifiant et codant les DME. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne aussi des procédés permettant de diagnostiquer, de traiter ou de prévenir des troubles liés à l'expression aberrante des DME.
CA002422530A 2000-09-29 2001-09-28 Enzymes humaines metabolisant les medicaments Abandoned CA2422530A1 (fr)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US23694700P 2000-09-29 2000-09-29
US60/236,947 2000-09-29
US23886400P 2000-10-06 2000-10-06
US60/238,864 2000-10-06
US24232300P 2000-10-20 2000-10-20
US60/242,323 2000-10-20
US24758100P 2000-11-09 2000-11-09
US60/247,581 2000-11-09
US24951900P 2000-11-16 2000-11-16
US60/249,519 2000-11-16
US25283400P 2000-11-22 2000-11-22
US60/252,834 2000-11-22
US25056700P 2000-11-30 2000-11-30
US60/250,567 2000-11-30
PCT/US2001/030662 WO2002026988A2 (fr) 2000-09-29 2001-09-28 Enzymes humaines métabolisant les médicaments

Publications (1)

Publication Number Publication Date
CA2422530A1 true CA2422530A1 (fr) 2002-04-04

Family

ID=27569418

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002422530A Abandoned CA2422530A1 (fr) 2000-09-29 2001-09-28 Enzymes humaines metabolisant les medicaments

Country Status (5)

Country Link
EP (1) EP1395656A2 (fr)
JP (1) JP2004526414A (fr)
AU (1) AU2001294929A1 (fr)
CA (1) CA2422530A1 (fr)
WO (1) WO2002026988A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1348021A2 (fr) * 2000-11-30 2003-10-01 Millenium Pharmaceuticals, Inc. 25206, nouveau membre humain de la famille deshydrogenase/reductase a chaine courte et utilisations de celui-ci

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2103756T3 (es) * 1990-06-22 1997-10-01 Hoffmann La Roche Deteccion de metabolizadores ineficaces de farmacos.

Also Published As

Publication number Publication date
WO2002026988A9 (fr) 2002-07-04
WO2002026988A3 (fr) 2003-01-30
JP2004526414A (ja) 2004-09-02
WO2002026988A2 (fr) 2002-04-04
AU2001294929A1 (en) 2002-04-08
EP1395656A2 (fr) 2004-03-10

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Legal Events

Date Code Title Description
FZDE Dead