CA2431203A1 - Mise en sequences polypeptide d'enzymes pouvant metaboliser une drogue et aussi, la codification en sequence polynucleotide - Google Patents

Mise en sequences polypeptide d'enzymes pouvant metaboliser une drogue et aussi, la codification en sequence polynucleotide Download PDF

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Publication number
CA2431203A1
CA2431203A1 CA002431203A CA2431203A CA2431203A1 CA 2431203 A1 CA2431203 A1 CA 2431203A1 CA 002431203 A CA002431203 A CA 002431203A CA 2431203 A CA2431203 A CA 2431203A CA 2431203 A1 CA2431203 A1 CA 2431203A1
Authority
CA
Canada
Prior art keywords
polynucleotide
polypeptide
seq
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002431203A
Other languages
English (en)
Inventor
Madhu M. Sanjanwala
Monique G. Yao
Janice Au-Young
Mariah R. Baughn
Chandra Arvizu
Huijun Z. Ring
Ernestine A. Lee
Li Ding
April J. A. Hafalia
Y. Tom Tang
Henry Yue
Catherine M. Tribouley
Dyung Aina M. Lu
Preeti G. Lal
Bridget A. Warren
Junming Yang
Narinder K. Chawla
Danniel B. Nguyen
Ameena R. Gandhi
Yan Lu
Craig H. Ison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of CA2431203A1 publication Critical patent/CA2431203A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La présente invention concerne des enzymes humaines métabolisant le médicament et des polynucléotides qui identifient et codent ces enzymes métabolisant le médicament. La présente invention se rapporte également à des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes ainsi qu'à des méthodes de diagnostic, de traitement ou de prévention des affections associées à l'expression aberrante des enzymes métabolisant le médicament.
CA002431203A 2000-12-08 2001-12-04 Mise en sequences polypeptide d'enzymes pouvant metaboliser une drogue et aussi, la codification en sequence polynucleotide Abandoned CA2431203A1 (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US25430800P 2000-12-08 2000-12-08
US60/254,308 2000-12-08
US25618900P 2000-12-15 2000-12-15
US60/256,189 2000-12-15
US25771300P 2000-12-21 2000-12-21
US60/257,713 2000-12-21
US26270601P 2001-01-19 2001-01-19
US60/262,706 2001-01-19
US26602001P 2001-02-02 2001-02-02
US60/266,020 2001-02-02
PCT/US2001/047429 WO2002046426A2 (fr) 2000-12-08 2001-12-04 Enzymes metabolisant le medicament

Publications (1)

Publication Number Publication Date
CA2431203A1 true CA2431203A1 (fr) 2002-06-13

Family

ID=27540347

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002431203A Abandoned CA2431203A1 (fr) 2000-12-08 2001-12-04 Mise en sequences polypeptide d'enzymes pouvant metaboliser une drogue et aussi, la codification en sequence polynucleotide

Country Status (5)

Country Link
EP (1) EP1370662A2 (fr)
JP (1) JP2005500006A (fr)
AU (1) AU2002239570A1 (fr)
CA (1) CA2431203A1 (fr)
WO (1) WO2002046426A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6664091B2 (en) 2000-12-18 2003-12-16 Millennium Pharmaceuticals, Inc. 53010, a human carboxylesterase family member and uses thereof
US6939698B2 (en) * 2001-02-15 2005-09-06 Millennium Pharmaceuticals, Inc. 33945, a human glycosyltransferase family member and uses therefor
WO2003057887A1 (fr) * 2001-12-28 2003-07-17 National Institute Of Advanced Industrial Science And Technology Nouvelles transferases udp-n-acetyl-d-galactosamine :polypeptide n-acetylgalactosamine et acides nucleiques codant ces dernieres
WO2003091402A2 (fr) * 2002-04-23 2003-11-06 University Of Georgia Research Foundation, Inc. Sequence de codage de n-acetylglucosaminyltransferase vb, cellules recombinantes et procedes associes
AU2003263560A1 (en) * 2002-10-03 2004-04-23 Pfizer Products Inc. Use of gst-omega-2 as a therapeutic target
US7790866B2 (en) 2002-11-21 2010-09-07 Chugai Seiyaku Kabushiki Kaisha Cancer-associated gene
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Also Published As

Publication number Publication date
JP2005500006A (ja) 2005-01-06
EP1370662A2 (fr) 2003-12-17
WO2002046426A3 (fr) 2003-09-04
WO2002046426A2 (fr) 2002-06-13
AU2002239570A1 (en) 2002-06-18

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Legal Events

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