CA2417769A1 - Enzymes metabolisant les medicaments - Google Patents

Enzymes metabolisant les medicaments Download PDF

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Publication number
CA2417769A1
CA2417769A1 CA002417769A CA2417769A CA2417769A1 CA 2417769 A1 CA2417769 A1 CA 2417769A1 CA 002417769 A CA002417769 A CA 002417769A CA 2417769 A CA2417769 A CA 2417769A CA 2417769 A1 CA2417769 A1 CA 2417769A1
Authority
CA
Canada
Prior art keywords
polynucleotide
polypeptide
seq
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002417769A
Other languages
English (en)
Inventor
Mariah R. Baughn
Christopher M. Bruns
Debopriya Das
Angelo M. Delegeane
Li Ding
Vicki S. Elliot
Ameena R. Gandhi
Jennifer A. Griffin
April J. A. Hafalia
Farrah A. Khan
Preeti Lal
Sally Lee
Dyung Aina M. Lu
Yan Lu
Chandra Patterson
Jayalaxmi Ramkumar
Huijun Z. Ring
Madhu S. Sanjanwala
Y. Tom Tang
Kavitha Thangavelu
Michael Thornton
Catherine M. Tribouley
Narinder K. Walia
Bridget A. Warren
Junming Yang
Monique G. Yao
Henry Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of CA2417769A1 publication Critical patent/CA2417769A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La présente invention concerne des enzymes humaines métabolisant les médicaments ou "DME" (pour "Drug Metabolizing Enzymes") et des polynucléotides identifiant et codant les DME. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne aussi des procédés permettant de diagnostiquer, de traiter ou de prévenir des troubles liés à l'expression aberrante des DME.
CA002417769A 2000-08-04 2001-08-03 Enzymes metabolisant les medicaments Abandoned CA2417769A1 (fr)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US22305500P 2000-08-04 2000-08-04
US60/223,055 2000-08-04
US22472800P 2000-08-11 2000-08-11
US60/224,728 2000-08-11
US22644000P 2000-08-18 2000-08-18
US60/226,440 2000-08-18
US22806700P 2000-08-24 2000-08-24
US60/228,067 2000-08-24
US23006300P 2000-08-31 2000-08-31
US60/230,063 2000-08-31
US23224400P 2000-09-13 2000-09-13
US60/232,244 2000-09-13
US23426900P 2000-09-20 2000-09-20
US60/234,269 2000-09-20
PCT/US2001/024382 WO2002012467A2 (fr) 2000-08-04 2001-08-03 Enzymes métabolisant les médicaments

Publications (1)

Publication Number Publication Date
CA2417769A1 true CA2417769A1 (fr) 2002-02-14

Family

ID=27569375

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002417769A Abandoned CA2417769A1 (fr) 2000-08-04 2001-08-03 Enzymes metabolisant les medicaments

Country Status (5)

Country Link
EP (1) EP1305425A2 (fr)
JP (1) JP2004518407A (fr)
AU (1) AU2001278154A1 (fr)
CA (1) CA2417769A1 (fr)
WO (1) WO2002012467A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020098174A1 (en) * 2000-03-31 2002-07-25 Rosana Kapeller-Libermann 33166, a human hydrolase-like molecule and uses thereof
CA2406639A1 (fr) * 2000-04-20 2001-11-01 Cytochroma Inc. Cytochrome humain p450 exprime dans le thymus (p450tec)
EP1295946B1 (fr) * 2000-06-29 2007-05-16 Seikagaku Corporation Sulfate transferase et adn codant cette enzyme
WO2002026945A2 (fr) * 2000-09-27 2002-04-04 Bayer Aktiengesellschaft Regulation d'une enzyme humaine de type aminotransferase
WO2002044357A2 (fr) 2000-11-30 2002-06-06 Millennium Pharmaceuticals, Inc. Procedes d'utilisation de 18903 dans le traitement de la douleur et des troubles lies a la douleur
RU2398882C2 (ru) 2004-07-22 2010-09-10 Эрасмус Юниверсити Медикал Сентр Роттердам СПОСОБ ПОЛУЧЕНИЯ АНТИГЕН-СВЯЗЫВАЮЩЕГО ДОМЕНА Vh ИСПОЛЬЗОВАНИЕ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744355A (en) * 1994-10-18 1998-04-28 Mayo Foundation For Medical Education And Research cDNA cloning and expression of human liver estrogen sulfotransferase
AUPO156596A0 (en) * 1996-08-09 1996-09-05 University Of Sydney, The Synthetic polynucleotides
US5756299A (en) * 1996-12-09 1998-05-26 Incyte Pharmaceuticals, Inc. Human carbonyl reductase
US6060253A (en) * 1997-01-23 2000-05-09 The United States Of America As Represented By The Department Of Health And Human Services Agents that bind to and inhibit human cytochrome P450 2D6
US20020068322A1 (en) * 2000-05-26 2002-06-06 Rachel Meyers 47765, a novel human lysyl oxidase and uses thereof

Also Published As

Publication number Publication date
JP2004518407A (ja) 2004-06-24
WO2002012467A3 (fr) 2002-12-27
AU2001278154A1 (en) 2002-02-18
EP1305425A2 (fr) 2003-05-02
WO2002012467A2 (fr) 2002-02-14

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Legal Events

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FZDE Dead