CA2415808A1 - Transporters and ion channels - Google Patents

Transporters and ion channels Download PDF

Info

Publication number
CA2415808A1
CA2415808A1 CA002415808A CA2415808A CA2415808A1 CA 2415808 A1 CA2415808 A1 CA 2415808A1 CA 002415808 A CA002415808 A CA 002415808A CA 2415808 A CA2415808 A CA 2415808A CA 2415808 A1 CA2415808 A1 CA 2415808A1
Authority
CA
Canada
Prior art keywords
polynucleotide
seq
polypeptide
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002415808A
Other languages
English (en)
French (fr)
Inventor
Brigitte E. Raumann
Michael Thornton
Li Ding
Henry Yue
Y. Tom Tang
Lee Harland
Neil Burford
Barrie D. Greene
Madhusudan S. Sanjanwala
Mariah R. Baughn
Monique G. Yao
Junming Yang
Chandra S. Arvizu
Ameena R. Gandhi
April J. A. Hafalia
Catherine M. Tribouley
Narinder K. Chawla
Janice Au-Young
Roderick T. Walsh
Jayalaxmi Ramkumar
Yan Lu
Dyung Aina M. Lu
Yalda Azimzai
Preeti Lal
Vicki S. Elliott
Danniel B. Nguyen
Yuming Xu
Jeffrey J. Seilhamer
Mark L. Borowsky
Farrah A. Khan
Liam Kearney
Kavitha Thangavelu
Debopriya Das
Jennifer L. Policky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2415808A1 publication Critical patent/CA2415808A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002415808A 2000-07-07 2001-07-05 Transporters and ion channels Abandoned CA2415808A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US21654700P 2000-07-07 2000-07-07
US60/216,547 2000-07-07
US21823200P 2000-07-14 2000-07-14
US60/218,232 2000-07-14
US22011200P 2000-07-21 2000-07-21
US60/220,112 2000-07-21
US22183900P 2000-07-28 2000-07-28
US60/221,839 2000-07-28
PCT/US2001/021448 WO2002004520A2 (en) 2000-07-07 2001-07-05 Transporters and ion channels

Publications (1)

Publication Number Publication Date
CA2415808A1 true CA2415808A1 (en) 2002-01-17

Family

ID=27499045

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002415808A Abandoned CA2415808A1 (en) 2000-07-07 2001-07-05 Transporters and ion channels

Country Status (5)

Country Link
EP (1) EP1313854A2 (de)
JP (1) JP2004513618A (de)
AU (1) AU2001273239A1 (de)
CA (1) CA2415808A1 (de)
WO (1) WO2002004520A2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236389A1 (en) * 2000-12-15 2003-12-25 Shimkets Richard A. Proteins, polynucleotides encoding them and methods of using the same
US6586179B1 (en) * 1999-07-13 2003-07-01 Icagen, Incorporated Human Eag2
WO2001057214A2 (en) * 2000-02-03 2001-08-09 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
US20020132298A1 (en) * 2000-11-14 2002-09-19 Millennium Pharmaceuticals, Inc. 67118, 67067, and 62092, human proteins and methods of use thereof
US20020042100A1 (en) * 2000-07-03 2002-04-11 Chunhua Yan Isolated human ion channel proteins, nucleic acid molecules encoding human ion channel proteins, and uses thereof
AU2001293100A1 (en) * 2000-09-25 2002-04-02 Millennium Pharmaceuticals, Inc. 49938, a human phospholipid transporter and uses therefor
GB2372503A (en) * 2000-10-19 2002-08-28 Glaxo Group Ltd Voltage-gated potassium channel polypeptides
EP1517917A4 (de) * 2000-11-20 2005-10-12 Merck & Co Inc Menschlicher erg2-kaliumkanal
US20020103337A1 (en) * 2000-12-04 2002-08-01 Chunhua Yan Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
UA79927C2 (en) * 2000-12-05 2007-08-10 Serono Genetics Inst Sa Polynucleotide, coding a polypeptide of potential-depending portal ionic human channel (canion), polypeptyde, antibody, method for identification of candidate modulator of canion-polypeptyde, method for treatment of bipolar disorder or schizophrenia and use of an antibody for production of drugs for treatment of schizophrenia or bipolar disorder
JP2005501505A (ja) * 2000-12-12 2005-01-20 ピーイー コーポレイション （エヌワイ） 単離ヒト輸送体タンパク質、ヒト輸送体タンパク質をコードする核酸分子、およびそれらの使用方法
WO2002050300A2 (en) * 2000-12-20 2002-06-27 Merck & Co., Inc. Human hyperpolarization-activated cyclic nucleotide-gated cation channel hcn3
EP1347050A4 (de) * 2000-12-27 2004-11-03 Yamanouchi Pharma Co Ltd Neue kaliumkanäle
US20040185527A1 (en) * 2001-01-22 2004-09-23 Gennady Merkulov Isolated human transporter proteins nucleic acid molecules encoding human transporter proteins and uses thereof
EP1273660A3 (de) * 2001-01-30 2004-01-07 Aeomica, Inc. Menschliches Natrium-Wasserstoff-Austauscher-ähnliches Protein 1
GB2390093A (en) * 2001-01-30 2003-12-31 Aeomica Inc Human sodium-hydrogen exchanger like protein 1
US20020142378A1 (en) * 2001-03-21 2002-10-03 Hongyu Zhang Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
GB2377445A (en) * 2001-04-20 2003-01-15 Smithkline Beecham Plc Ion channel vanilloid receptor, VANILREP7
EP1258496A1 (de) * 2001-05-09 2002-11-20 Millenium Pharmaceuticals, Inc. 63751, ein Mitglied der humanen Zucker-transporterfamilie und seine Verwendungen
US20040234978A1 (en) * 2001-05-10 2004-11-25 Yusuke Nakamura Novel potential-dependent cation channel protein
EP1456397A4 (de) * 2001-07-10 2005-05-11 Millennium Pharm Inc 52908, ein menschlicher kaliumkanal, und verwendungen davon
US20030044933A1 (en) * 2001-08-15 2003-03-06 Millennium Pharmaceuticals, Inc. 96895, a human sodium-hydrogen exchanger family member and uses therefor
WO2003038094A1 (en) * 2001-10-30 2003-05-08 Bayer Healthcare Ag Regulation of human glucose transporter
WO2003037929A1 (en) * 2001-11-01 2003-05-08 Bayer Healthcare Ag Polynucleotides encoding human potassium channel polypeptides
WO2003054190A1 (fr) * 2001-12-21 2003-07-03 Takeda Chemical Industries, Ltd. Nouvelles proteines et adn correspondants
AU2002367140A1 (en) * 2001-12-27 2003-07-15 Takeda Chemical Industries, Ltd. Human sglt homolog promoter and use thereof
JP2003310281A (ja) * 2002-01-18 2003-11-05 Takeda Chem Ind Ltd 新規タンパク質およびそのｄｎａ
AU2003226797A1 (en) * 2002-04-16 2003-10-27 Bayer Healthcare Ag Regulation of human transient receptor potential channel
WO2004039405A1 (ja) * 2002-10-29 2004-05-13 Takeda Pharmaceutical Company Limited Ｓｇｌｔホモログ用途
WO2004081041A1 (en) * 2003-03-10 2004-09-23 Bayer Healthcare Ag Organic anion transporting (oat)-like protein ust3-like1 and uses thereof
WO2005029086A2 (en) * 2003-09-22 2005-03-31 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with organic cation transporter slc22a10 (ust3-like2) (slc22a10)
EA022359B1 (ru) * 2009-09-25 2015-12-30 Острэйлиан Сентр Фор Плант Фанкшенл Дженомикс Пти Лтд. Активность катионных каналов
US20230357391A1 (en) * 2020-08-04 2023-11-09 Exelixis, Inc. Cd47 binding agents and uses thereof
CN115322248B (zh) * 2022-05-18 2024-05-17 大连理工大学 一种钾离子通道蛋白AlAKT1、其编码基因及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002522018A (ja) * 1998-07-24 2002-07-23 財団法人相模中央化学研究所 疎水性ドメインを有するヒト蛋白質およびそれをコードするｄｎａ
WO2000026253A1 (en) * 1998-11-03 2000-05-11 Smithkline Beecham P.L.C. Human potassium channel (h-traak)
JP2003521227A (ja) * 1998-11-04 2003-07-15 インサイト・ファーマスーティカルズ・インコーポレイテッド 膜輸送タンパク質
CA2350334C (en) * 1998-11-09 2013-07-16 Centre National De La Recherche Scientifique (C.N.R.S.) New family of mammalian potassium channels, their cloning and their use, especially for the screening of drugs
US6664373B1 (en) * 1999-03-01 2003-12-16 Millennium Pharmaceuticals, Inc. TWIK-5 potassium channel polypeptides and uses therefor
US6670149B1 (en) * 1999-03-01 2003-12-30 Millennium Pharmaceuticals, Inc. TWIK-5 potassium channel nucleic acids and uses therefor
CA2392757A1 (en) * 2000-01-31 2001-08-02 Human Genome Sciences Inc. Nucleic acids, proteins, and antibodies

Also Published As

Publication number Publication date
EP1313854A2 (de) 2003-05-28
AU2001273239A1 (en) 2002-01-21
JP2004513618A (ja) 2004-05-13
WO2002004520A3 (en) 2003-03-20
WO2002004520A2 (en) 2002-01-17

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