CA2415808A1 - Transporteurs et canaux ioniques - Google Patents

Transporteurs et canaux ioniques Download PDF

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Publication number
CA2415808A1
CA2415808A1 CA002415808A CA2415808A CA2415808A1 CA 2415808 A1 CA2415808 A1 CA 2415808A1 CA 002415808 A CA002415808 A CA 002415808A CA 2415808 A CA2415808 A CA 2415808A CA 2415808 A1 CA2415808 A1 CA 2415808A1
Authority
CA
Canada
Prior art keywords
polynucleotide
seq
polypeptide
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002415808A
Other languages
English (en)
Inventor
Brigitte E. Raumann
Michael Thornton
Li Ding
Henry Yue
Y. Tom Tang
Lee Harland
Neil Burford
Barrie D. Greene
Madhusudan S. Sanjanwala
Mariah R. Baughn
Monique G. Yao
Junming Yang
Chandra S. Arvizu
Ameena R. Gandhi
April J. A. Hafalia
Catherine M. Tribouley
Narinder K. Chawla
Janice Au-Young
Roderick T. Walsh
Jayalaxmi Ramkumar
Yan Lu
Dyung Aina M. Lu
Yalda Azimzai
Preeti Lal
Vicki S. Elliott
Danniel B. Nguyen
Yuming Xu
Jeffrey J. Seilhamer
Mark L. Borowsky
Farrah A. Khan
Liam Kearney
Kavitha Thangavelu
Debopriya Das
Jennifer L. Policky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2415808A1 publication Critical patent/CA2415808A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention a trait à des transporteurs et à des canaux ioniques humains (TRICH) ainsi qu'à des polynucléotides qui identifient et codent TRICH. Cette invention concerne, en outre, des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Par ailleurs, elle concerne des méthodes diagnostiques, thérapeutiques ou prophylactiques de troubles associés à l'expression aberrante de TRICH.
CA002415808A 2000-07-07 2001-07-05 Transporteurs et canaux ioniques Abandoned CA2415808A1 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US21654700P 2000-07-07 2000-07-07
US60/216,547 2000-07-07
US21823200P 2000-07-14 2000-07-14
US60/218,232 2000-07-14
US22011200P 2000-07-21 2000-07-21
US60/220,112 2000-07-21
US22183900P 2000-07-28 2000-07-28
US60/221,839 2000-07-28
PCT/US2001/021448 WO2002004520A2 (fr) 2000-07-07 2001-07-05 Transporteurs et canaux ioniques

Publications (1)

Publication Number Publication Date
CA2415808A1 true CA2415808A1 (fr) 2002-01-17

Family

ID=27499045

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002415808A Abandoned CA2415808A1 (fr) 2000-07-07 2001-07-05 Transporteurs et canaux ioniques

Country Status (5)

Country Link
EP (1) EP1313854A2 (fr)
JP (1) JP2004513618A (fr)
AU (1) AU2001273239A1 (fr)
CA (1) CA2415808A1 (fr)
WO (1) WO2002004520A2 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236389A1 (en) * 2000-12-15 2003-12-25 Shimkets Richard A. Proteins, polynucleotides encoding them and methods of using the same
US6586179B1 (en) * 1999-07-13 2003-07-01 Icagen, Incorporated Human Eag2
AU2001241446A1 (en) * 2000-02-03 2001-08-14 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
US20020132298A1 (en) * 2000-11-14 2002-09-19 Millennium Pharmaceuticals, Inc. 67118, 67067, and 62092, human proteins and methods of use thereof
US20020042100A1 (en) * 2000-07-03 2002-04-11 Chunhua Yan Isolated human ion channel proteins, nucleic acid molecules encoding human ion channel proteins, and uses thereof
AU2001293100A1 (en) * 2000-09-25 2002-04-02 Millennium Pharmaceuticals, Inc. 49938, a human phospholipid transporter and uses therefor
GB2372503A (en) * 2000-10-19 2002-08-28 Glaxo Group Ltd Voltage-gated potassium channel polypeptides
WO2002042417A2 (fr) * 2000-11-20 2002-05-30 Merck & Co., Inc. Canal potassium erg2 humain
US20020103337A1 (en) * 2000-12-04 2002-08-01 Chunhua Yan Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
UA79927C2 (en) * 2000-12-05 2007-08-10 Serono Genetics Inst Sa Polynucleotide, coding a polypeptide of potential-depending portal ionic human channel (canion), polypeptyde, antibody, method for identification of candidate modulator of canion-polypeptyde, method for treatment of bipolar disorder or schizophrenia and use of an antibody for production of drugs for treatment of schizophrenia or bipolar disorder
WO2002048363A2 (fr) * 2000-12-12 2002-06-20 Pe Corporation (Ny) Proteines de transport humaines isolees, molecules d'acide nucleique codant des proteines de transport humaines, et leur utilisation
CA2432274A1 (fr) * 2000-12-20 2002-06-27 Merck & Co., Inc. Hcn3 de canal cationique declenche par des nucleotides cycliques et actives par hyperpolarisation chez l'homme
EP1347050A4 (fr) * 2000-12-27 2004-11-03 Yamanouchi Pharma Co Ltd Nouveau canal potassique
CA2435828A1 (fr) * 2001-01-22 2002-10-10 Pe Corporation (Ny) Proteines de transport humaines, isolees, molecules d'acide nucleique les codant et leurs utilisations
EP1273660A3 (fr) * 2001-01-30 2004-01-07 Aeomica, Inc. Protéine 1 similaire à un échangeur de Sodium-Hydrogène
GB2390093A (en) * 2001-01-30 2003-12-31 Aeomica Inc Human sodium-hydrogen exchanger like protein 1
US20020142378A1 (en) * 2001-03-21 2002-10-03 Hongyu Zhang Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
GB2377445A (en) * 2001-04-20 2003-01-15 Smithkline Beecham Plc Ion channel vanilloid receptor, VANILREP7
EP1258496A1 (fr) * 2001-05-09 2002-11-20 Millenium Pharmaceuticals, Inc. 63751, membre de la familie de transporteurs humains du sucre et leur utilisations
CA2446708A1 (fr) * 2001-05-10 2002-12-19 Mochida Pharmaceutical Co., Ltd. Nouvelle proteine du canal cation dependant du voltage
AU2002320536A1 (en) * 2001-07-10 2003-01-29 Millennium Pharmaceuticals, Inc. 52908, a human potassium channel, and uses thereof
US20030044933A1 (en) * 2001-08-15 2003-03-06 Millennium Pharmaceuticals, Inc. 96895, a human sodium-hydrogen exchanger family member and uses therefor
WO2003038094A1 (fr) * 2001-10-30 2003-05-08 Bayer Healthcare Ag Regulation du transporteur de glucose humain
WO2003037929A1 (fr) * 2001-11-01 2003-05-08 Bayer Healthcare Ag Polynucleotides codant des polypeptides du canal potassique humain
US20050124793A1 (en) * 2001-12-21 2005-06-09 Takeda Chemical Industries, Ltd. Novel proteins and dnas thereof
AU2002367140A1 (en) * 2001-12-27 2003-07-15 Takeda Chemical Industries, Ltd. Human sglt homolog promoter and use thereof
EP1473303B1 (fr) 2002-01-18 2010-02-24 Takeda Pharmaceutical Company Limited Transporteur d'acide biliaire dépendant de sodium et son utilisation
WO2003087158A2 (fr) * 2002-04-16 2003-10-23 Bayer Healthcare Ag Regulation de canal potentiel recepteur transitoire humain
EP1557178A4 (fr) * 2002-10-29 2009-07-22 Takeda Pharmaceutical Utilisation de l'homologue de sglt
US7338781B2 (en) 2003-03-10 2008-03-04 Bayer Healthcare Ag Organic anion transporting (oat)-like protein UST3-LIKE1 and uses thereof
WO2005029086A2 (fr) * 2003-09-22 2005-03-31 Bayer Healthcare Ag Agents diagnostiques et therapeutiques pour des maladies liees au transporteur slc22a10 (ust3-like2) (slc22a10) de cations organiques
AU2010300093B2 (en) * 2009-09-25 2015-07-09 Australian Centre For Plant Functional Genomics Pty Ltd Cation channel activity
EP4192501A1 (fr) * 2020-08-04 2023-06-14 Exelixis, Inc. Agents de liaison à cd47 et leurs utilisations
CN115322248B (zh) * 2022-05-18 2024-05-17 大连理工大学 一种钾离子通道蛋白AlAKT1、其编码基因及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2336225A1 (fr) * 1998-07-24 2000-02-03 Sagami Chemical Research Center Proteines humaines a domaines hydrophobes et adn codant pour ces proteines
EP1127073A1 (fr) * 1998-11-03 2001-08-29 Smithkline Beecham Plc Canal potassique humain (h-traak)
EP1144443A3 (fr) * 1998-11-04 2001-12-05 Incyte Pharmaceuticals, Inc. Proteines de transport membranaire
DE69938667D1 (de) * 1998-11-09 2008-06-19 Centre Nat Rech Scient Neue familie von säugetier-kaliumkanälen, ihre klonierung und ihre verwendung, besonders für das drogenscreening
US6664373B1 (en) * 1999-03-01 2003-12-16 Millennium Pharmaceuticals, Inc. TWIK-5 potassium channel polypeptides and uses therefor
US6670149B1 (en) * 1999-03-01 2003-12-30 Millennium Pharmaceuticals, Inc. TWIK-5 potassium channel nucleic acids and uses therefor
WO2001055447A1 (fr) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Acides nucléiques, proteines et anticorps

Also Published As

Publication number Publication date
JP2004513618A (ja) 2004-05-13
AU2001273239A1 (en) 2002-01-21
EP1313854A2 (fr) 2003-05-28
WO2002004520A3 (fr) 2003-03-20
WO2002004520A2 (fr) 2002-01-17

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