CA2410084A1 - Transporteurs et canaux ioniques - Google Patents

Transporteurs et canaux ioniques Download PDF

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Publication number
CA2410084A1
CA2410084A1 CA002410084A CA2410084A CA2410084A1 CA 2410084 A1 CA2410084 A1 CA 2410084A1 CA 002410084 A CA002410084 A CA 002410084A CA 2410084 A CA2410084 A CA 2410084A CA 2410084 A1 CA2410084 A1 CA 2410084A1
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CA
Canada
Prior art keywords
polynucleotide
polypeptide
seq
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002410084A
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English (en)
Inventor
Michael Thornton
Narinder K. Chawla
Henry Yue
Danniel B. Nguyen
Preeti G. Lal
Ameena R. Gandhi
Catherine M. Tribouley
Monique G. Yao
Jayalaxmi Ramkumar
Janice Au-Young
Yan Lu
Tom Y. Tang
Yalda Azimzai
Christopher M. Bruns
Jennifer A. Griffin
Junming Yang
Madhu M. Sanjanwala
Brigitte E. Raumann
Ernestine A. Lee
April J. A. Hafalia
Mariah R. Baughn
Barrie D. Green
Farrah A. Khan
Liam Kearney
Vicki S. Elliot
Jeffrey J. Seilhamer
Jennifer L. Policky
Mark L. Borowsky
Neil Burford
Li Ding
Dyung Aina M. Lu
Jennifer L. Jackson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2410084A1 publication Critical patent/CA2410084A1/fr
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
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    • A61P17/06—Antipsoriatics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/06—Antihyperlipidemics
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P31/14—Antivirals for RNA viruses
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)

Abstract

L'invention concerne des transporteurs et des canaux ioniques humains (TRICH), ainsi que des polynucléotides qui permettent d'identifier et de coder ces TRICH. Elle concerne aussi des vecteurs d'expression, des cellules hôtes, des anticorps et des antagonistes. Elle concerne enfin des méthodes de diagnostic, de traitement ou de prévention de troubles associés à l'expression aberrante de TRICH.
CA002410084A 2000-05-26 2001-05-25 Transporteurs et canaux ioniques Abandoned CA2410084A1 (fr)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US20842400P 2000-05-26 2000-05-26
US60/208,424 2000-05-26
US20900100P 2000-06-01 2000-06-01
US60/209,001 2000-06-01
US21058800P 2000-06-08 2000-06-08
US60/210,588 2000-06-08
US21233500P 2000-06-16 2000-06-16
US60/212,335 2000-06-16
US21374700P 2000-06-22 2000-06-22
US60/213,747 2000-06-22
US21539100P 2000-06-29 2000-06-29
US60/215,391 2000-06-29
PCT/US2001/017065 WO2001092304A2 (fr) 2000-05-26 2001-05-25 Transporteurs et canaux ioniques

Publications (1)

Publication Number Publication Date
CA2410084A1 true CA2410084A1 (fr) 2001-12-06

Family

ID=27559000

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002410084A Abandoned CA2410084A1 (fr) 2000-05-26 2001-05-25 Transporteurs et canaux ioniques

Country Status (5)

Country Link
EP (1) EP1320548A2 (fr)
JP (1) JP2004512016A (fr)
AU (1) AU2001265002A1 (fr)
CA (1) CA2410084A1 (fr)
WO (1) WO2001092304A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1538161A3 (fr) * 1999-09-24 2005-06-15 Human Genome Sciences, Inc. 32 protéines secretées humaines
US7118853B2 (en) * 2000-07-26 2006-10-10 Applied Genomics, Inc. Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors
US20020076780A1 (en) * 2000-08-16 2002-06-20 Turner C. Alexander Novel human ion channel proteins and polynucleotides encoding the same
US20020172998A1 (en) * 2000-09-25 2002-11-21 Millennium Pharmaceuticals, Inc. 32612, a novel human peptide transporter and uses therefor
US20030166522A1 (en) * 2000-12-12 2003-09-04 Ketchum Karen A. Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002055701A2 (fr) * 2000-12-15 2002-07-18 Millennium Pharm Inc Proteines humaines 8099, 46455, 54414, 53736, 67076, 67102, 44181, 67084fl, et 67084 alt, et procedes d'utilisation
JP2004537283A (ja) * 2001-02-09 2004-12-16 インサイト・ゲノミックス・インコーポレイテッド 輸送体及びイオンチャネル
GB2375349A (en) * 2001-02-13 2002-11-13 Glaxo Group Ltd Chloride intracellular channel-related proteins
AU2002367140A1 (en) * 2001-12-27 2003-07-15 Takeda Chemical Industries, Ltd. Human sglt homolog promoter and use thereof
US7125676B2 (en) 2002-02-25 2006-10-24 Vanderbilt University Expression system for human brain-specific voltage-gated sodium channel, type 1
AU2003275713A1 (en) * 2002-10-29 2004-05-25 Takeda Pharmaceutical Company Limited Use of sglt homolog
WO2004087752A2 (fr) * 2003-04-04 2004-10-14 Ingenium Pharmaceuticals Ag Genes de proteines de type spinster, produits d'expression, modele animal non humain : utilisations dans le traitement des troubles metaboliques humains

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH693031A5 (de) * 1997-11-20 2003-01-31 Hoffmann La Roche Nucleinsäure, die einen Nervengewebe-Natriumkanal kodiert.
WO2000003015A2 (fr) * 1998-07-10 2000-01-20 Incyte Pharmaceuticals, Inc. Homologues de proteine humaine de transport
EP1210423A1 (fr) * 1999-08-20 2002-06-05 Active Pass Pharmaceuticals, Inc. Nouveau transporteur abc et ses utilisations
WO2001066732A1 (fr) * 2000-03-06 2001-09-13 Merck Patent Gmbh Transporteur abc humain s'exprimant dans le foie, atil

Also Published As

Publication number Publication date
AU2001265002A1 (en) 2001-12-11
WO2001092304A3 (fr) 2003-03-06
WO2001092304A2 (fr) 2001-12-06
EP1320548A2 (fr) 2003-06-25
JP2004512016A (ja) 2004-04-22

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