CA2375414A1 - Proteines de regulateur de transcription humaines - Google Patents
Proteines de regulateur de transcription humaines Download PDFInfo
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- CA2375414A1 CA2375414A1 CA002375414A CA2375414A CA2375414A1 CA 2375414 A1 CA2375414 A1 CA 2375414A1 CA 002375414 A CA002375414 A CA 002375414A CA 2375414 A CA2375414 A CA 2375414A CA 2375414 A1 CA2375414 A1 CA 2375414A1
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- txreg
- polynucleotide
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- 150000008300 phosphoramidites Chemical class 0.000 description 1
- 238000000206 photolithography Methods 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
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- 108010025826 prolyl-leucyl-arginine Proteins 0.000 description 1
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- XJMOSONTPMZWPB-UHFFFAOYSA-M propidium iodide Chemical compound [I-].[I-].C12=CC(N)=CC=C2C2=CC=C(N)C=C2[N+](CCC[N+](C)(CC)CC)=C1C1=CC=CC=C1 XJMOSONTPMZWPB-UHFFFAOYSA-M 0.000 description 1
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- 230000012846 protein folding Effects 0.000 description 1
- 230000018883 protein targeting Effects 0.000 description 1
- 230000004850 protein–protein interaction Effects 0.000 description 1
- 244000000040 protozoan parasite Species 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 230000006340 racemization Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000000163 radioactive labelling Methods 0.000 description 1
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- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 231100001274 therapeutic index Toxicity 0.000 description 1
- 238000005382 thermal cycling Methods 0.000 description 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 description 1
- 229940094937 thioredoxin Drugs 0.000 description 1
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- 230000005945 translocation Effects 0.000 description 1
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- 230000017105 transposition Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 101150081616 trpB gene Proteins 0.000 description 1
- 101150111232 trpB-1 gene Proteins 0.000 description 1
- 108010015666 tryptophyl-leucyl-glutamic acid Proteins 0.000 description 1
- 108010038745 tryptophylglycine Proteins 0.000 description 1
- 239000000225 tumor suppressor protein Substances 0.000 description 1
- 230000005760 tumorsuppression Effects 0.000 description 1
- 238000010396 two-hybrid screening Methods 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 108010020532 tyrosyl-proline Proteins 0.000 description 1
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- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 description 1
- 229940045145 uridine Drugs 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 108010009962 valyltyrosine Proteins 0.000 description 1
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- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
L'invention concerne des protéines de régulateur de transcription humaines (TXREG) et des polynucléotides qui identifient et codent pour TXREG. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne également des méthodes permettant de diagnostiquer, de traiter ou de prévenir des affections associées à l'expression de TXREG.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14010999P | 1999-06-18 | 1999-06-18 | |
US60/140,109 | 1999-06-18 | ||
PCT/US2000/016766 WO2000078954A2 (fr) | 1999-06-18 | 2000-06-15 | Proteines de regulateur de transcription humaines |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2375414A1 true CA2375414A1 (fr) | 2000-12-28 |
Family
ID=22489799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002375414A Abandoned CA2375414A1 (fr) | 1999-06-18 | 2000-06-15 | Proteines de regulateur de transcription humaines |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1190050A2 (fr) |
JP (1) | JP2003517290A (fr) |
AU (1) | AU5623000A (fr) |
CA (1) | CA2375414A1 (fr) |
WO (1) | WO2000078954A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001027270A1 (fr) | 1999-10-08 | 2001-04-19 | Chugai Seiyaku Kabushiki Kaisha | Gene ys68 associe a l'hematopoiese precoce |
JP4112976B2 (ja) * | 2000-11-09 | 2008-07-02 | 株式会社Jimro | Pca2501遺伝子 |
US20040072997A1 (en) * | 2000-12-20 | 2004-04-15 | Alsobrook John P. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
US20030219739A1 (en) * | 2001-01-30 | 2003-11-27 | Glass David J. | Novel nucleic acid and polypeptide molecules |
JP3810731B2 (ja) * | 2002-11-29 | 2006-08-16 | 独立行政法人科学技術振興機構 | 哺乳動物のToll様受容体3に結合する新規アダプタータンパク質およびその遺伝子 |
WO2004078112A2 (fr) * | 2003-03-07 | 2004-09-16 | Asahi Kasei Pharma Corporation | Gene induisant l'apoptose |
WO2006033460A1 (fr) * | 2004-09-24 | 2006-03-30 | Oncotherapy Science, Inc. | PROCÉDÉ SERVANT À DIAGNOSTIQUER DES CANCERS DES POUMONS NON À PETITES CELLULES PAR L'ACTIVITÉ DE L'ARNt-DIHYDROURIDINE SYNTHÉTASE DE URLC8 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5726288A (en) * | 1989-11-13 | 1998-03-10 | Massachusetts Institute Of Technology | Localization and characterization of the Wilms' tumor gene |
US5861495A (en) * | 1997-01-21 | 1999-01-19 | Incyte Pharmaceuticals, Inc. | Human zinc binding proteins |
-
2000
- 2000-06-15 JP JP2001505696A patent/JP2003517290A/ja active Pending
- 2000-06-15 EP EP00941530A patent/EP1190050A2/fr not_active Withdrawn
- 2000-06-15 AU AU56230/00A patent/AU5623000A/en not_active Abandoned
- 2000-06-15 CA CA002375414A patent/CA2375414A1/fr not_active Abandoned
- 2000-06-15 WO PCT/US2000/016766 patent/WO2000078954A2/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU5623000A (en) | 2001-01-09 |
WO2000078954A3 (fr) | 2001-08-23 |
WO2000078954A2 (fr) | 2000-12-28 |
EP1190050A2 (fr) | 2002-03-27 |
JP2003517290A (ja) | 2003-05-27 |
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