CA2415272C - Improvements in and relating to the use of honey in dressings - Google Patents
Improvements in and relating to the use of honey in dressings Download PDFInfo
- Publication number
- CA2415272C CA2415272C CA002415272A CA2415272A CA2415272C CA 2415272 C CA2415272 C CA 2415272C CA 002415272 A CA002415272 A CA 002415272A CA 2415272 A CA2415272 A CA 2415272A CA 2415272 C CA2415272 C CA 2415272C
- Authority
- CA
- Canada
- Prior art keywords
- honey
- dressing
- wound
- woven fibre
- flexible dressing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 235000012907 honey Nutrition 0.000 title claims abstract description 199
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 149
- 238000004519 manufacturing process Methods 0.000 claims abstract description 33
- 235000010443 alginic acid Nutrition 0.000 claims description 23
- 229920000615 alginic acid Polymers 0.000 claims description 23
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims description 20
- 229940072056 alginate Drugs 0.000 claims description 20
- 230000000694 effects Effects 0.000 claims description 19
- 239000000835 fiber Substances 0.000 claims description 18
- 150000002978 peroxides Chemical class 0.000 claims description 14
- 210000000416 exudates and transudate Anatomy 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 6
- 230000000717 retained effect Effects 0.000 claims description 5
- 238000010521 absorption reaction Methods 0.000 claims description 4
- 235000010410 calcium alginate Nutrition 0.000 claims description 3
- 239000000648 calcium alginate Substances 0.000 claims description 3
- 229960002681 calcium alginate Drugs 0.000 claims description 3
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 claims description 3
- 208000025865 Ulcer Diseases 0.000 claims description 2
- 238000005299 abrasion Methods 0.000 claims description 2
- 206010000269 abscess Diseases 0.000 claims description 2
- 238000005470 impregnation Methods 0.000 claims description 2
- 231100000397 ulcer Toxicity 0.000 claims description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims 2
- 235000010413 sodium alginate Nutrition 0.000 claims 2
- 239000000661 sodium alginate Substances 0.000 claims 2
- 229940005550 sodium alginate Drugs 0.000 claims 2
- 230000003902 lesion Effects 0.000 claims 1
- 206010052428 Wound Diseases 0.000 abstract description 141
- 239000000203 mixture Substances 0.000 abstract description 67
- 239000000463 material Substances 0.000 abstract description 66
- 238000000034 method Methods 0.000 abstract description 9
- 230000008859 change Effects 0.000 abstract description 2
- 230000035876 healing Effects 0.000 description 20
- 239000003795 chemical substances by application Substances 0.000 description 16
- 230000001684 chronic effect Effects 0.000 description 12
- 229920001817 Agar Polymers 0.000 description 9
- 150000001875 compounds Chemical class 0.000 description 9
- 230000004888 barrier function Effects 0.000 description 7
- 239000000499 gel Substances 0.000 description 7
- 239000003349 gelling agent Substances 0.000 description 7
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 6
- 230000009286 beneficial effect Effects 0.000 description 6
- 229910052791 calcium Inorganic materials 0.000 description 6
- 239000011575 calcium Substances 0.000 description 6
- 239000007921 spray Substances 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 6
- 240000003553 Leptospermum scoparium Species 0.000 description 5
- 235000016887 Leptospermum scoparium Nutrition 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 5
- 230000001070 adhesive effect Effects 0.000 description 5
- 239000008272 agar Substances 0.000 description 5
- 239000003242 anti bacterial agent Substances 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 239000006260 foam Substances 0.000 description 5
- 239000000416 hydrocolloid Substances 0.000 description 5
- 208000015181 infectious disease Diseases 0.000 description 5
- 239000011782 vitamin Substances 0.000 description 5
- 229940088594 vitamin Drugs 0.000 description 5
- 235000013343 vitamin Nutrition 0.000 description 5
- 229930003231 vitamin Natural products 0.000 description 5
- 230000029663 wound healing Effects 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 230000000845 anti-microbial effect Effects 0.000 description 4
- 230000023555 blood coagulation Effects 0.000 description 4
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 150000001768 cations Chemical class 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 239000000419 plant extract Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 2
- 239000006096 absorbing agent Substances 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000007792 addition Methods 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 230000037390 scarring Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000000451 tissue damage Effects 0.000 description 2
- 231100000827 tissue damage Toxicity 0.000 description 2
- 235000019155 vitamin A Nutrition 0.000 description 2
- 239000011719 vitamin A Substances 0.000 description 2
- 229940045997 vitamin a Drugs 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 241001514662 Leptospermum Species 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- -1 Vitamin A) Natural products 0.000 description 1
- 206010048038 Wound infection Diseases 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 229940124326 anaesthetic agent Drugs 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 159000000032 aromatic acids Chemical class 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- FFBHFFJDDLITSX-UHFFFAOYSA-N benzyl N-[2-hydroxy-4-(3-oxomorpholin-4-yl)phenyl]carbamate Chemical compound OC1=C(NC(=O)OCC2=CC=CC=C2)C=CC(=C1)N1CCOCC1=O FFBHFFJDDLITSX-UHFFFAOYSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 229910052729 chemical element Inorganic materials 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000008029 eradication Effects 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 125000004387 flavanoid group Chemical group 0.000 description 1
- 108010025899 gelatin film Proteins 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 230000001524 infective effect Effects 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000001706 oxygenating effect Effects 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F13/0283—Apparatus or processes for manufacturing adhesive dressings or bandages for making adhesive or cohesive tape or fabrics therefor, e.g. coating or mechanical treatments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
- A61F13/0213—Adhesive bandages or dressings with fluid retention members the fluid retention member being a layer of hydrocolloid, gel forming material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
- A61F13/0226—Adhesive bandages or dressings with fluid retention members characterised by the support layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Manufacturing & Machinery (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ505514 | 2000-06-30 | ||
| NZ505514A NZ505514A (en) | 2000-06-30 | 2000-06-30 | Method of manufacturing a wound dressing for the application of honey |
| PCT/NZ2001/000129 WO2002000269A1 (en) | 2000-06-30 | 2001-06-29 | The use of honey in wound dressings |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2415272A1 CA2415272A1 (en) | 2002-01-03 |
| CA2415272C true CA2415272C (en) | 2009-11-03 |
Family
ID=19927975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002415272A Expired - Lifetime CA2415272C (en) | 2000-06-30 | 2001-06-29 | Improvements in and relating to the use of honey in dressings |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7714183B2 (enExample) |
| EP (1) | EP1299134A1 (enExample) |
| JP (1) | JP2004527453A (enExample) |
| CN (1) | CN1444488A (enExample) |
| AU (2) | AU8270701A (enExample) |
| CA (1) | CA2415272C (enExample) |
| NZ (1) | NZ505514A (enExample) |
| WO (1) | WO2002000269A1 (enExample) |
| ZA (1) | ZA200300788B (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE260669T1 (de) * | 1999-12-09 | 2004-03-15 | Apimed Medical Honey Ltd | Medizinische verbände enthaltend gelartiger honig |
| GB0110715D0 (en) * | 2001-05-02 | 2001-06-27 | Acordis Speciality Fibres Ltd | Wound dressing |
| GB2382527A (en) * | 2001-12-03 | 2003-06-04 | Acordis Speciality Fibres Ltd | Wound dressings |
| AU2002950744A0 (en) | 2002-08-13 | 2002-09-12 | Medihoney Pty Ltd | Composition |
| ITMI20030414A1 (it) * | 2003-03-06 | 2004-09-07 | Biofarm S R L Ora Biofarmitalia S P A | Tampone con strato di gel con attivita' cosmetica o terapeutica. |
| NZ533368A (en) * | 2004-06-08 | 2008-06-30 | Univ Waikato | Isolation process |
| AU2006272366B2 (en) * | 2005-07-19 | 2011-09-22 | Honey Research & Development Pty Ltd | Therapeutic honey and method of producing same |
| WO2007009185A1 (en) * | 2005-07-19 | 2007-01-25 | Honey Research & Development Pty Ltd | Therapeutic honey and method of producing same |
| WO2007045931A2 (en) * | 2005-10-22 | 2007-04-26 | Brightwake Limited | Compositions and dressings for the treatment of wounds |
| WO2007048193A1 (en) * | 2005-10-26 | 2007-05-03 | Medihoney Pty Ltd | Hydrocolloid composition |
| CA2628295C (en) * | 2005-11-02 | 2016-02-23 | Birgit Riesinger | Absorptive element to be mounted on human or animal skin surfaces |
| US20070098671A1 (en) * | 2005-11-02 | 2007-05-03 | Martin Gregory D | Composition and method of treatment for irritated skin |
| GB2432790A (en) * | 2005-12-01 | 2007-06-06 | David William Richardson | A wound dressing with active ingredients |
| DE202006007877U1 (de) * | 2006-01-25 | 2006-07-27 | Riesinger, Birgit | Vorgefertigte Wundauflage mit Superabsorber |
| GB2435426A (en) * | 2006-02-23 | 2007-08-29 | David William Richardson | Wound healing system and dressing containing a dried form of a liquid |
| CN100522258C (zh) | 2007-04-04 | 2009-08-05 | 中国人民解放军第三军医大学第一附属医院 | 一种去除皮肤表浅爆炸冲击伤异物的清创贴 |
| US20090047388A1 (en) * | 2007-08-15 | 2009-02-19 | Wright Iv Salmon L | Calcium fortified creamed honey |
| GB0810404D0 (en) * | 2008-06-06 | 2008-07-09 | Manuka Medical Ltd | Compositions |
| CH699182B1 (fr) * | 2008-07-17 | 2012-03-15 | Care Cosmeceuticals Sarl | Mélanges de miel d'abeilles pour le traitement dermatologique des plaies chroniques. |
| GB0813541D0 (en) * | 2008-07-24 | 2008-08-27 | Brightwake Ltd | Honey wound dressing |
| JP2010095454A (ja) * | 2008-10-14 | 2010-04-30 | Cyclochem:Kk | 抗菌組成物 |
| WO2010082846A1 (en) * | 2008-12-24 | 2010-07-22 | Comvita New Zealand Limited | Medical and nutritional formulations |
| CN101879324A (zh) * | 2010-07-02 | 2010-11-10 | 西南大学 | 壳聚糖复合医用敷料的制备方法 |
| CN102406958B (zh) * | 2011-12-02 | 2014-04-09 | 褚加冕 | 一种杀菌蜂蜜敷料的制备方法 |
| AU2013249992B2 (en) | 2012-04-17 | 2015-03-26 | Apimed Medical Honey Limited | Immunostimulatory compositions and methods of manufacture |
| US20140358058A1 (en) * | 2013-05-30 | 2014-12-04 | Flextronics International Usa, Inc. | Wound dressing formed with a two-sided adhesive band |
| US9107974B2 (en) | 2013-07-11 | 2015-08-18 | Links Medical Products, Inc | Honey impregnated composite dressing having super absorbency and intelligent management of wound exudate and method of making same |
| USD745690S1 (en) | 2013-07-11 | 2015-12-15 | Links Medical Products, Inc. | Honey patterned foam structure for holding medical grade manuka honey |
| US9358256B2 (en) | 2013-07-11 | 2016-06-07 | Links Medical Products, Inc. | Gap-patterned foam dressing and method of making same |
| JP2016524916A (ja) | 2013-07-19 | 2016-08-22 | アルトリア クライアント サービシーズ リミテッド ライアビリティ カンパニー | ニコチンをオーラル製品中に組み込むための方法およびシステム |
| US20150030688A1 (en) * | 2013-07-25 | 2015-01-29 | Saint Louis University | Honey and growth factor eluting scaffold for wound healing and tissue engineering |
| US10086017B2 (en) | 2013-09-19 | 2018-10-02 | Medline Industries, Inc. | Wound dressing containing polysaccharides |
| US10342891B2 (en) * | 2013-09-19 | 2019-07-09 | Medline Industries, Inc. | Wound dressing containing saccharide and collagen |
| GB2519072B (en) * | 2013-10-07 | 2019-12-04 | Welland Medical Ltd | Composition comprising collagen and honey |
| US20170087194A1 (en) | 2013-11-25 | 2017-03-30 | Biomedical Concepts Llc | Composition, system and method for treating skin |
| JP6825913B2 (ja) | 2014-04-30 | 2021-02-03 | マトケ・ホールディングス・リミテッド | 抗菌組成物 |
| WO2016007776A1 (en) * | 2014-07-09 | 2016-01-14 | Derma Sciences, Inc. | Honey-based foam compositions |
| JP6861151B2 (ja) | 2014-08-05 | 2021-04-21 | ザ ユニバーシティ オブ メンフィス | 骨および軟組織の治癒および再生を向上させるための組成物および方法 |
| WO2016123539A1 (en) | 2015-01-29 | 2016-08-04 | Wardell Mark R | Wound healing compositions involving medicinal honey, mineral ions, and methylglyoxal, and methods of use |
| CN105012994B (zh) * | 2015-08-25 | 2018-02-16 | 东莞市达庆医疗器械有限公司 | 一种医用生物泌尿水凝胶功能敷料及其制备方法 |
| CN105169464B (zh) * | 2015-09-24 | 2018-05-15 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种天然蜂蜜伤口敷料及其制备方法与应用 |
| CN105617455A (zh) * | 2016-03-30 | 2016-06-01 | 吴美燕 | 一种中药创可贴药膏的制备方法 |
| IT201600093678A1 (it) * | 2016-09-19 | 2018-03-19 | Federico Pecorari | Medicazione emostatica per accesso vascolare |
| JP7683874B2 (ja) | 2016-12-06 | 2025-05-27 | ザ テキサス エーアンドエム ユニバーシティ システム | 抗菌形状記憶ポリマー |
| WO2019018997A1 (zh) | 2017-07-25 | 2019-01-31 | 惠州华阳医疗器械有限公司 | 一种抗菌藻酸盐纤维、其敷料的制备方法及应用 |
| GB201716986D0 (en) | 2017-10-16 | 2017-11-29 | Matoke Holdings Ltd | Antimicrobial compositions |
| CN107929792A (zh) * | 2017-12-16 | 2018-04-20 | 广东泰宝医疗科技股份有限公司 | 一种具有止痛功能的活性炭纤维敷料及其制备方法 |
| IL270762B (en) | 2019-11-19 | 2021-10-31 | Sion Biotext Medical Ltd | Wound dressing comprising a combination of hydrogel and honey, method of preparation and uses thereof |
| CN110935056A (zh) * | 2019-12-30 | 2020-03-31 | 山东星之诚生物科技有限公司 | 一种高吸湿性藻酸盐敷料制备方法 |
| US12419917B2 (en) | 2021-04-23 | 2025-09-23 | Ndal Mfg Inc | Compositions and methods for treatment of conditions using fractionated honey |
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|---|---|---|---|---|
| US2432541A (en) * | 1945-09-12 | 1947-12-16 | Peck John Mcclelland | Adhesive bandage |
| DE959051C (de) * | 1954-06-20 | 1957-02-28 | Dr Johanna Budwig | Menstruationshilfe |
| AU546556B2 (en) * | 1981-08-18 | 1985-09-05 | Courtaulds Plc | Alginate fibre material and process |
| US5197945A (en) * | 1988-05-31 | 1993-03-30 | Minnesota Mining And Manufacturing Company | Alginate wound dressing of good integrity |
| GB8816909D0 (en) * | 1988-07-15 | 1988-08-17 | Netzsch Mastermix Ltd | Mixing & dispersing apparatus |
| US4950475A (en) * | 1988-07-19 | 1990-08-21 | Imaginative Research Associates, Inc. | Novel film-forming gels with high concentrations of humectants and emollients |
| DE3827561C1 (enExample) * | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
| US5407675A (en) | 1990-08-10 | 1995-04-18 | Etemad-Moghadam; Parviz | Method and composition for use on the scalp and eyebrow region of a subject |
| JPH05209318A (ja) * | 1992-01-30 | 1993-08-20 | Teijin Ltd | 吸液性に優れたアルギン酸カルシウム繊維及び医療用被覆材 |
| GB9218749D0 (en) * | 1992-09-04 | 1992-10-21 | Courtaulds Plc | Alginate gels |
| US5653699A (en) * | 1994-09-13 | 1997-08-05 | Polymedica Industries, Inc. | Spyrosorbent wound dressings for exudate management |
| US5980875A (en) * | 1996-04-12 | 1999-11-09 | Mousa; Mahmoud A. | Honey preparations |
| JPH10251141A (ja) * | 1997-03-05 | 1998-09-22 | Masao Nakayama | 外用火傷塗不動特効剤 |
| FR2769504B1 (fr) * | 1997-10-13 | 2000-03-10 | Oreal | Utilisation du miel en tant qu'agent diminuant l'adhesion des micro-organismes |
| AT406731B (de) * | 1998-04-24 | 2000-08-25 | Dado Suleiman | Stoffgemisch zur topischen anwendung |
| WO2000009176A1 (en) * | 1998-08-11 | 2000-02-24 | Susanna Elizabeth Chalmers | A wound treatment composition and a wound dressing containing it |
| US6319510B1 (en) | 1999-04-20 | 2001-11-20 | Alayne Yates | Gum pad for delivery of medication to mucosal tissues |
| ATE260669T1 (de) * | 1999-12-09 | 2004-03-15 | Apimed Medical Honey Ltd | Medizinische verbände enthaltend gelartiger honig |
| WO2001067888A1 (en) * | 2000-03-17 | 2001-09-20 | Phillip Roy Caskey | Improvements in and relating to honey based products |
| GB0110715D0 (en) * | 2001-05-02 | 2001-06-27 | Acordis Speciality Fibres Ltd | Wound dressing |
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2000
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| WO2002000269A1 (en) | 2002-01-03 |
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| CA2415272A1 (en) | 2002-01-03 |
| EP1299134A1 (en) | 2003-04-09 |
| JP2004527453A (ja) | 2004-09-09 |
| CN1444488A (zh) | 2003-09-24 |
| US20040127826A1 (en) | 2004-07-01 |
| ZA200300788B (en) | 2004-02-19 |
| WO2002000269A8 (en) | 2002-02-28 |
| US7714183B2 (en) | 2010-05-11 |
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