CA2409068A1 - Novel dual oxidases as mitogenic and endocrine regulators - Google Patents

Novel dual oxidases as mitogenic and endocrine regulators Download PDF

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Publication number
CA2409068A1
CA2409068A1 CA002409068A CA2409068A CA2409068A1 CA 2409068 A1 CA2409068 A1 CA 2409068A1 CA 002409068 A CA002409068 A CA 002409068A CA 2409068 A CA2409068 A CA 2409068A CA 2409068 A1 CA2409068 A1 CA 2409068A1
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CA
Canada
Prior art keywords
seq
protein
activity
fragment
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002409068A
Other languages
English (en)
French (fr)
Inventor
J. David Lambeth
Bernard P. Lassegue
Kathy K. Griendling
Rebecca S. Arnold
Guangjie Cheng
Lisa Sharling
Guy Benian
William A. Edens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emory University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2409068A1 publication Critical patent/CA2409068A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Obesity (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002409068A 2000-05-15 2001-05-14 Novel dual oxidases as mitogenic and endocrine regulators Abandoned CA2409068A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20444100P 2000-05-15 2000-05-15
US60/204,441 2000-05-15
US22242100P 2000-08-01 2000-08-01
US60/222,421 2000-08-01
PCT/US2001/015573 WO2001087957A2 (en) 1999-11-10 2001-05-14 Novel dual oxidases as mitogenic and endocrine regulators

Publications (1)

Publication Number Publication Date
CA2409068A1 true CA2409068A1 (en) 2001-11-22

Family

ID=26899479

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002409068A Abandoned CA2409068A1 (en) 2000-05-15 2001-05-14 Novel dual oxidases as mitogenic and endocrine regulators

Country Status (5)

Country Link
EP (1) EP1285071A2 (ja)
JP (1) JP2003533217A (ja)
AU (2) AU2001264596B2 (ja)
CA (1) CA2409068A1 (ja)
WO (1) WO2001087957A2 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130199D0 (en) * 2001-12-17 2002-02-06 Syngenta Mogen Bv New nematode feeding assay
GR1004419B (el) * 2002-06-19 2004-01-15 Κιντζιοσασπυριδωναευαγγελου Μεθοδοσαελεγχουατησακυτταρικησαδιαιρεσησακαιααναπτυξης
CA2493061A1 (en) 2002-07-16 2004-01-22 Guangjie Cheng Regulatory protein for nox enzymes
WO2006133145A2 (en) * 2005-06-06 2006-12-14 Caprion Pharmaceuticals, Inc. Tat-007 and methods of assessing and treating cancer
CN104120186B (zh) * 2014-08-06 2017-07-11 广西壮族自治区妇幼保健院 先天性甲状腺功能减低症多基因测序引物及检测方法
CN107019798B (zh) * 2016-02-02 2021-02-12 上海尚泰生物技术有限公司 Duox2修饰的dc疫苗及其靶向杀伤胰腺癌起始细胞的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1131430B1 (en) * 1998-11-10 2007-01-17 Emory University Mitogenic regulators
FR2798391B1 (fr) * 1999-09-15 2001-12-14 Inst Nat Sante Rech Med Enzyme thyroidienne nadph oxydase, acide nucleique codant pour cette enzyme et leurs applications
CA2396036A1 (en) * 1999-12-30 2001-07-12 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use

Also Published As

Publication number Publication date
EP1285071A2 (en) 2003-02-26
AU2001264596B2 (en) 2006-06-15
WO2001087957A3 (en) 2002-04-25
WO2001087957A9 (en) 2002-12-12
AU6459601A (en) 2001-11-26
WO2001087957A2 (en) 2001-11-22
JP2003533217A (ja) 2003-11-11

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued