CA2409068A1 - Nouvelles oxydases doubles utilisees comme regulateurs mitogeniques et endocriniens - Google Patents
Nouvelles oxydases doubles utilisees comme regulateurs mitogeniques et endocriniens Download PDFInfo
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Obesity (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
La présente invention porte sur de nouveaux gènes codant pour la production de nouvelles protéines impliquées dans la génération d'intermédiaires d'oxygène réactif et dans des réactions peroxydatives qui affectent des fonctions biologiques telles que la division cellulaire, la biosynthèse de l'hormone thyroïdienne et la cirrhose des tissus du foie. La présente invention porte également sur des vecteurs contenant ces gènes, sur des cellules transfectées par ces vecteurs, sur des anticorps contre ces nouvelles protéines, sur des kits de détection, sur la localisation et la mesure de ces gènes et protéines et sur des procédés de détermination de l'activité des médicaments affectant l'activité des protéines de cette invention.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20444100P | 2000-05-15 | 2000-05-15 | |
| US60/204,441 | 2000-05-15 | ||
| US22242100P | 2000-08-01 | 2000-08-01 | |
| US60/222,421 | 2000-08-01 | ||
| PCT/US2001/015573 WO2001087957A2 (fr) | 1999-11-10 | 2001-05-14 | Nouvelles oxydases doubles utilisees comme regulateurs mitogeniques et endocriniens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2409068A1 true CA2409068A1 (fr) | 2001-11-22 |
Family
ID=26899479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002409068A Abandoned CA2409068A1 (fr) | 2000-05-15 | 2001-05-14 | Nouvelles oxydases doubles utilisees comme regulateurs mitogeniques et endocriniens |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1285071A2 (fr) |
| JP (1) | JP2003533217A (fr) |
| AU (2) | AU6459601A (fr) |
| CA (1) | CA2409068A1 (fr) |
| WO (1) | WO2001087957A2 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0130199D0 (en) * | 2001-12-17 | 2002-02-06 | Syngenta Mogen Bv | New nematode feeding assay |
| GR1004419B (el) * | 2002-06-19 | 2004-01-15 | Κιντζιοσασπυριδωναευαγγελου | Μεθοδοσαελεγχουατησακυτταρικησαδιαιρεσησακαιααναπτυξης |
| US7029673B2 (en) | 2002-07-16 | 2006-04-18 | Emory University | Regulatory protein for Nox enzymes |
| WO2006133145A2 (fr) * | 2005-06-06 | 2006-12-14 | Caprion Pharmaceuticals, Inc. | Tat-007 et procédés d'évaluation et de traitement de cancer |
| CN104120186B (zh) * | 2014-08-06 | 2017-07-11 | 广西壮族自治区妇幼保健院 | 先天性甲状腺功能减低症多基因测序引物及检测方法 |
| CN107019798B (zh) * | 2016-02-02 | 2021-02-12 | 上海尚泰生物技术有限公司 | Duox2修饰的dc疫苗及其靶向杀伤胰腺癌起始细胞的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000028031A2 (fr) * | 1998-11-10 | 2000-05-18 | Emory University | Nouveaux regulateurs mitogeniques |
| FR2798391B1 (fr) * | 1999-09-15 | 2001-12-14 | Inst Nat Sante Rech Med | Enzyme thyroidienne nadph oxydase, acide nucleique codant pour cette enzyme et leurs applications |
| EP1242598A2 (fr) * | 1999-12-30 | 2002-09-25 | Corixa Corporation | Composes pour l'immunotherapie et le diagnostic du cancer du colon et procedes d'utilisation |
-
2001
- 2001-05-14 WO PCT/US2001/015573 patent/WO2001087957A2/fr active Application Filing
- 2001-05-14 CA CA002409068A patent/CA2409068A1/fr not_active Abandoned
- 2001-05-14 AU AU6459601A patent/AU6459601A/xx active Pending
- 2001-05-14 AU AU2001264596A patent/AU2001264596B2/en not_active Ceased
- 2001-05-14 EP EP01939033A patent/EP1285071A2/fr not_active Withdrawn
- 2001-05-14 JP JP2001585175A patent/JP2003533217A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001087957A2 (fr) | 2001-11-22 |
| AU2001264596B2 (en) | 2006-06-15 |
| WO2001087957A3 (fr) | 2002-04-25 |
| WO2001087957A9 (fr) | 2002-12-12 |
| JP2003533217A (ja) | 2003-11-11 |
| AU6459601A (en) | 2001-11-26 |
| EP1285071A2 (fr) | 2003-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |