CA2407219A1 - Pain signaling molecules - Google Patents
Pain signaling molecules Download PDFInfo
- Publication number
- CA2407219A1 CA2407219A1 CA002407219A CA2407219A CA2407219A1 CA 2407219 A1 CA2407219 A1 CA 2407219A1 CA 002407219 A CA002407219 A CA 002407219A CA 2407219 A CA2407219 A CA 2407219A CA 2407219 A1 CA2407219 A1 CA 2407219A1
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- mrg
- polypeptide
- antibody
- drg
- protein
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US60/202,027 | 2000-05-04 | ||
| US22234400P | 2000-08-01 | 2000-08-01 | |
| US60/222,344 | 2000-08-01 | ||
| US09/704,707 | 2000-11-03 | ||
| US09/704,707 US7691604B1 (en) | 2000-05-04 | 2000-11-03 | MRG polypeptides and nucleic acids encoding the same |
| US28549301P | 2001-04-19 | 2001-04-19 | |
| US60/285,493 | 2001-04-19 | ||
| PCT/US2001/014519 WO2001083555A2 (en) | 2000-05-04 | 2001-05-04 | Pain signaling molecules |
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| CA2407219A1 true CA2407219A1 (en) | 2001-11-08 |
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| AT (1) | ATE312919T1 (enExample) |
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| CA (1) | CA2407219A1 (enExample) |
| DE (1) | DE60115878T2 (enExample) |
| WO (1) | WO2001083555A2 (enExample) |
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| US20020064822A1 (en) * | 2000-03-13 | 2002-05-30 | Ming-Hui Wei | Isolated human G-protein coupled receptors, nucleic acid molecules encoding human GPCR proteins, and uses thereof |
| US20030092035A1 (en) | 2000-05-04 | 2003-05-15 | Anderson David J. | Pain signaling molecules |
| JP2004511806A (ja) * | 2000-10-17 | 2004-04-15 | アストラゼネカ・アクチエボラーグ | アッセイ |
| US20040076951A1 (en) * | 2000-10-25 | 2004-04-22 | Ming-Hui Wei | Isolated human G-protein coupled receptors, nucleic acid molecules encoding human GPCR proteins, and uses thereof |
| US20040143092A1 (en) * | 2001-02-08 | 2004-07-22 | Alex Smolyar | Regulation of human dorsal root receptor-like g protein-coupled receptor |
| DE10225443A1 (de) * | 2002-06-08 | 2003-12-18 | Aventis Pharma Gmbh | Verfahren zur Identifizierung von Agonisten oder Antagonisten für den G-Protein gekoppelten Rezeptor mas like 1 |
| AU2003275712A1 (en) * | 2002-10-29 | 2004-05-25 | Takeda Pharmaceutical Company Limited | H17t213-transgenic animal, novel h17t213 protein and dna thereof |
| US7056685B1 (en) | 2002-11-05 | 2006-06-06 | Amgen Inc. | Receptor ligands and methods of modulating receptors |
| DE10310758A1 (de) * | 2003-03-11 | 2004-09-23 | Grünenthal GmbH | Identifizierung von schmerzrelevanten Genen der SNSR (Sensory Neuron Specific Receptor)-Familie |
| WO2005003763A2 (en) * | 2003-06-18 | 2005-01-13 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with mas related g-protein coupled receptor 3 (mrgx3) |
| JP2007507538A (ja) | 2003-10-02 | 2007-03-29 | エラン ファーマシューティカルズ，インコーポレイテッド | 疼痛軽減方法 |
| WO2005114208A1 (en) * | 2004-05-13 | 2005-12-01 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with mas-related gene mrgd (mrgd) |
| WO2006005470A2 (en) * | 2004-07-15 | 2006-01-19 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with mas related g-protein coupled receptor e (mrge) |
| WO2006066599A2 (en) * | 2004-12-22 | 2006-06-29 | Rheoscience A/S | Mas related g protein coupled receptors as drug targets |
| CN112266931B (zh) * | 2020-10-15 | 2022-04-29 | 海湃泰克(北京)生物医药科技有限公司 | 特异性表达hMRGPRX4的转基因大鼠的构建方法及其应用 |
| CN118956756B (zh) * | 2024-09-29 | 2025-07-25 | 中国人民解放军空军军医大学 | 一种痛感受器皮肤类器官芯片及其培养基、构建方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9704836D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Pharma Inc | Novel receptor |
| JP2000023676A (ja) * | 1998-07-14 | 2000-01-25 | Asahi Chem Ind Co Ltd | ７回膜貫通型受容体蛋白質ｅｒｇ５ |
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- 2001-05-04 EP EP01933045A patent/EP1280904B1/en not_active Expired - Lifetime
- 2001-05-04 AT AT01933045T patent/ATE312919T1/de not_active IP Right Cessation
- 2001-05-04 WO PCT/US2001/014519 patent/WO2001083555A2/en not_active Ceased
- 2001-05-04 CA CA002407219A patent/CA2407219A1/en not_active Abandoned
- 2001-05-04 AU AU2001259508A patent/AU2001259508A1/en not_active Abandoned
- 2001-05-04 JP JP2001580979A patent/JP2003533188A/ja active Pending
- 2001-05-04 DE DE60115878T patent/DE60115878T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001083555A3 (en) | 2002-05-02 |
| ATE312919T1 (de) | 2005-12-15 |
| DE60115878D1 (de) | 2006-01-19 |
| DE60115878T2 (de) | 2006-08-24 |
| EP1280904A2 (en) | 2003-02-05 |
| JP2003533188A (ja) | 2003-11-11 |
| EP1280904B1 (en) | 2005-12-14 |
| WO2001083555A2 (en) | 2001-11-08 |
| AU2001259508A1 (en) | 2001-11-12 |
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