CA2406476C - Water for medical treatment, production method thereof, and dialysis apparatus using water for medical treatment as dialysis liquid - Google Patents
Water for medical treatment, production method thereof, and dialysis apparatus using water for medical treatment as dialysis liquid Download PDFInfo
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Abstract
A dialysis apparatus that utilizes water as dialysis liquid. The water has the capacity to abolish the Superoxide Anion Radical which may trigger various diseases. The apparatus comprises electrolytic water generation means for electrolyzing water, boiling means for boiling cathode water sent from the electrolytic water generation means, and dialysis liquid supply means for supplying the cathode water introduced from the boiling means as dialysis liquid.
Description
WATER FOR MEDICAL TREATMENT, PRODUCTION METHOD THEREOF, AND DIALYSIS APPARATUS USING WATER FOR MEDICAL TREATMENT
AS DIALYSIS LIQUID
This application is a division of Canadian Patent Application Serial Number 2,303,676 filed July 4, 1996 which is itself a division of Canadian Patent Application Serial Number 2,180,487 filed on July 4, 1996.
The present invention generally relates to water for medical treatment, and more particularly, to water for medical treatment that has the capacity to abolish the Superoxide Anion Radical: OZ'~ (referred to as "SAR" hereinafter), generated in a body. The invention also relates to a method of producing such water for medical treatment. Furthermore, the present invention relates to a dialysis apparatus that utilizes such water as dialysis liquid.
Significant advancement has been seen in the field of modern medicine, and the variety and number of new medicines and drugs available on the market are increasing. Developments in mediomechanical instrumentation has allowed a more accurate understanding of the human body, so that increasingly appropriate treatments can be applied. Many people graduate from medical colleges every year to practice medicine, and techniques in medical treatment are progressing.
However, the number of people with medical disorders is increasing in spite of such progress in medical science. Accordingly, the total cost of medical fees shows no decrease. It is considered that this is due to the fact that symptoms of a disease are treated nosotropically, and that fundamental therapy is not applied.
Recently, it has been confirmed that the SAR generated within the human body is the trigger of various diseases and illnesses. It is considered that SAR
is generated as a result of the oxygen in blood being subjected to the effect of ischemic re-perfusion, intracorporeal bacteria, uric acid in blood, fat, and by the reduction of sugars or by the influence of neutrophils.
There is a great amount of SAR in the blood of individuals with certain diseases or with abundant uric acid, fat, and/or sugar in the blood. SAR
reacts with DNA and the like in the body to induce symptoms and disease such as allergic dermatitis.
Processes or methods of abolishing the SAR from blood are now drawing the attention of doctors and people working at medical institutes all over the world.
Conventionally, ~i-carotene, vitamin C, vitamin E and SOD (Super Oxide~Dismutase) are typically known to abolish SAR. However, there is a problem that excessive ingestion thereof will cause reactions such as oxidation effect. .
In view of the foregoing, an object of the present invention is to provide water for medical treatment that has the capacity to abolish SAR, which may become the trigger of various diseases.
Another object of the present invention is to provide a method of producing such water for medical treatment.
A further object of the present invention is to provide a dialysis apparatus that utilizes such water for medical treatment as dialysis liquid.
According to an aspect of the present invention which is claimed in Serial No. 2,180,487, there is provided water for medical treatment which has an oxidation-reduction potential value within the range of -150 mV ~ 0 mV
measured using a platinum electrode. Sterile water having an oxidation-reduction potential measured value of -68 mV ~ +55 mV is obtained by boiling the water.
The inventors found that by electrolyzing water under particular conditions set forth in the following, water is generated at the cathode side (referred to as cathode water hereinafter) Which is rich in electrons (e ) and protons (H+) with a potency for abolishing SAR generated within the body.
The reaction mechanism of the cathode water for removing SAR is as follows:
OZ ' (Superoxide Anion Radical) + a + 2H' ~ HZOz (hydrogen peroxide) H20z + e' ~ HO~ + HO-HO~ + e- + H+ , Hz0 More specifically, it is believed that SAR which is the cause of various diseases is combined with electrons (e ) and protons (H+) included in the cathode water to be reduced and is then converted into H20 (water) and is thus abolished.
According to another aspect of the present invention, claimed in Serial No. 2,180,487, a method of producing water for medical treatment includes the step of preparing an electrolytic water generator. The electrolytic water generator includes a cathode chamber with a cathode and an anode chamber with an anode, wherein said chambers are separated by a diaphragm. Raw water including at least natrium, kalium, magnesium, and calcium ions is supplied to respective anode and cathode chambers. A current within the range of 0.16 mAlcm2 ~ 3.22 mA/cm2 per two electrodes and one diaphragm is applied for at least 0.5 seconds and not more than 5 seconds across the cathode and the anode to electrolyze the raw water. Then, the water within the cathode chamber is extracted. It was found that the cathode water obtained by such a method has the potency to remove SAR.
According to a third aspect of the present invention, claimed in Serial No. 2,303,676, a dialysis apparatus includes an electrolytic water generation apparatus for electrolyzing water, a filter apparatus for filtering cathode water fed from an electrolytic liquid reservoir tank, and a dialysis liquid supply apparatus for supplying the cathode water introduced from the filter apparatus as dialysis liquid.
Since the dialysis apparatus of the present invention includes an electrolytic water generation apparatus, cathode water that can remove SAR can be supplied to the human body as dialysis liquid. Therefore, SAR in the blood of a patient can be removed in addition to the effect of hemodialysis.
According to still another aspect of the present invention, a dialysis apparatus includes an electrolytic water generation means for electrolyzing water, boiling means for boiling cathode water sent from the electrolytic water generation means, and a dialysis liquid supply means for supplying cathode water introduced from the boiling apparatus as dialysis liquid.
Since this dialysis apparatus includes a boiling apparatus, the bacteria in the cathode water can be killed, and thus the cathode water is disinfected.
AS DIALYSIS LIQUID
This application is a division of Canadian Patent Application Serial Number 2,303,676 filed July 4, 1996 which is itself a division of Canadian Patent Application Serial Number 2,180,487 filed on July 4, 1996.
The present invention generally relates to water for medical treatment, and more particularly, to water for medical treatment that has the capacity to abolish the Superoxide Anion Radical: OZ'~ (referred to as "SAR" hereinafter), generated in a body. The invention also relates to a method of producing such water for medical treatment. Furthermore, the present invention relates to a dialysis apparatus that utilizes such water as dialysis liquid.
Significant advancement has been seen in the field of modern medicine, and the variety and number of new medicines and drugs available on the market are increasing. Developments in mediomechanical instrumentation has allowed a more accurate understanding of the human body, so that increasingly appropriate treatments can be applied. Many people graduate from medical colleges every year to practice medicine, and techniques in medical treatment are progressing.
However, the number of people with medical disorders is increasing in spite of such progress in medical science. Accordingly, the total cost of medical fees shows no decrease. It is considered that this is due to the fact that symptoms of a disease are treated nosotropically, and that fundamental therapy is not applied.
Recently, it has been confirmed that the SAR generated within the human body is the trigger of various diseases and illnesses. It is considered that SAR
is generated as a result of the oxygen in blood being subjected to the effect of ischemic re-perfusion, intracorporeal bacteria, uric acid in blood, fat, and by the reduction of sugars or by the influence of neutrophils.
There is a great amount of SAR in the blood of individuals with certain diseases or with abundant uric acid, fat, and/or sugar in the blood. SAR
reacts with DNA and the like in the body to induce symptoms and disease such as allergic dermatitis.
Processes or methods of abolishing the SAR from blood are now drawing the attention of doctors and people working at medical institutes all over the world.
Conventionally, ~i-carotene, vitamin C, vitamin E and SOD (Super Oxide~Dismutase) are typically known to abolish SAR. However, there is a problem that excessive ingestion thereof will cause reactions such as oxidation effect. .
In view of the foregoing, an object of the present invention is to provide water for medical treatment that has the capacity to abolish SAR, which may become the trigger of various diseases.
Another object of the present invention is to provide a method of producing such water for medical treatment.
A further object of the present invention is to provide a dialysis apparatus that utilizes such water for medical treatment as dialysis liquid.
According to an aspect of the present invention which is claimed in Serial No. 2,180,487, there is provided water for medical treatment which has an oxidation-reduction potential value within the range of -150 mV ~ 0 mV
measured using a platinum electrode. Sterile water having an oxidation-reduction potential measured value of -68 mV ~ +55 mV is obtained by boiling the water.
The inventors found that by electrolyzing water under particular conditions set forth in the following, water is generated at the cathode side (referred to as cathode water hereinafter) Which is rich in electrons (e ) and protons (H+) with a potency for abolishing SAR generated within the body.
The reaction mechanism of the cathode water for removing SAR is as follows:
OZ ' (Superoxide Anion Radical) + a + 2H' ~ HZOz (hydrogen peroxide) H20z + e' ~ HO~ + HO-HO~ + e- + H+ , Hz0 More specifically, it is believed that SAR which is the cause of various diseases is combined with electrons (e ) and protons (H+) included in the cathode water to be reduced and is then converted into H20 (water) and is thus abolished.
According to another aspect of the present invention, claimed in Serial No. 2,180,487, a method of producing water for medical treatment includes the step of preparing an electrolytic water generator. The electrolytic water generator includes a cathode chamber with a cathode and an anode chamber with an anode, wherein said chambers are separated by a diaphragm. Raw water including at least natrium, kalium, magnesium, and calcium ions is supplied to respective anode and cathode chambers. A current within the range of 0.16 mAlcm2 ~ 3.22 mA/cm2 per two electrodes and one diaphragm is applied for at least 0.5 seconds and not more than 5 seconds across the cathode and the anode to electrolyze the raw water. Then, the water within the cathode chamber is extracted. It was found that the cathode water obtained by such a method has the potency to remove SAR.
According to a third aspect of the present invention, claimed in Serial No. 2,303,676, a dialysis apparatus includes an electrolytic water generation apparatus for electrolyzing water, a filter apparatus for filtering cathode water fed from an electrolytic liquid reservoir tank, and a dialysis liquid supply apparatus for supplying the cathode water introduced from the filter apparatus as dialysis liquid.
Since the dialysis apparatus of the present invention includes an electrolytic water generation apparatus, cathode water that can remove SAR can be supplied to the human body as dialysis liquid. Therefore, SAR in the blood of a patient can be removed in addition to the effect of hemodialysis.
According to still another aspect of the present invention, a dialysis apparatus includes an electrolytic water generation means for electrolyzing water, boiling means for boiling cathode water sent from the electrolytic water generation means, and a dialysis liquid supply means for supplying cathode water introduced from the boiling apparatus as dialysis liquid.
Since this dialysis apparatus includes a boiling apparatus, the bacteria in the cathode water can be killed, and thus the cathode water is disinfected.
The foregoing and other objects, features, aspects and advantages of the present invention will become more apparent from the following detailed description of the present invention when taken in conjunction with the accompanying drawings.
Figure 1 is a diagram showing the concept of an electrolytic water generator for producing water for medical treatment according to the first embodiment of the present invention;
Figure 2 is a diagram showing the capacity of the water to abolish SAR
from blood for medical treatment according to the first embodiment using the blood of a 72-year-old male patient;
Figure 3 shows the capacity of the water to abolish SAR from blood for medical treatment according to the first embodiment using the blood of a 38-year-old mate patient;
Figure 4 shows the effect of the water of the present invention on the blood of a patient suffering from acute pancreatitis;
Figure 5 is a diagram showing the concept of a conventional dialysis apparatus for describing a dialysis apparatus according to the second embodiment of the present invention;
Figure 6 is a diagram showing the concept of the dialysis apparatus of the second embodiment;
Figure 7 shows the characterizing portion of the dialysis apparatus of the second embodiment in detail;
Figure 8 is a diagram showing the concept of a dialysis apparatus according to the third embodiment of the present invention.
First Embodiment Referring to Figure 1, an electrolytic water generator (HD-30) includes a cathode chamber 2 with a cathode 1 and an anode chamber 4 with an anode 3.
Cathode chamber 2 is separated from anode chamber 4 by a diaphragm 5. A
cathode liquid outlet pipe 6 from which cathode liquid is drawn out is connected to cathode chamber 2. A drain pipe 7 for discharging anode water outward is connected to anode chamber 4. A feed pipe 8 is connected to respective cathode and anode chambers 2 and 4 so that raw water such as tap water, ground water, or water from a well is supplied, which includes at least natrium, kalium, magnesium, and calcium.
Raw water such as tap water, ground water, or well water is supplied to cathode chamber 2 and anode chamber 4. A current within the range of 0.16 mA/cm2 5 ~ 3.2 mA/cmZ per two electrodes and one diaphragm is applied across cathode electrode 1 and anode electrode 3 for at least 0.5 seconds and not more than 5 seconds at room temperature (18°C ~ 22°C) to electrolyze the raw water. As a result, water for medical treatment, which is the cathode water, is obtained having the following properties. The oxidation-reduction potential (ORP) indicated in the present specification is measured using a platinum electrode by an ORP measuring apparatus (RM-12P) of Toa Denpa Co. Ltd.
pH 8.0 ~ 9.5 ORP (Oxidation-Reduction Potential): ~ 0 mV ~ 150 mV
Cathode water of various characteristics was produced to study the capacity of the water to abolish SAR from blood.
The graph of Figure 2 indicates the amount of SAR in a mixture of blood extracted from a 72-year-old male patient and the above-described cathode water over time. In the graph of Figure 2, time is plotted along the abscissa, and the amount of SAR is plotted along the ordinate. The curved line labeled "control" at the right side of the graph shows data when the above-described cathode water is not added.
The curved lines labeled 1 °, 2°, 3°, and 4° at the right side of the graph indicate data corresponding to the PBS test number.
Figure 3 shows the result of a similar test using blood extracted from a 38-year-old male patient.
Referring to Figures 2 and 3, it was found that cathode water having an oxidation-reduction potential (ORP) of -150 mV ~ 0 mV has the greatest potency to remove SAR.
Figure 4 shows the result of tracing the amount of SAR over time from a mixture of cathode water according to the present invention and blood extracted from a patient suffering from acute pancreatitis. The line labeled "TAP WATER"
shows data obtained from a mixture of tap water and the above-described blood, and the line labeled "REDUCED WATER" indicates data obtained from a mixture of cathode water of the present invention and blood. It is appreciated that the amount of SAR does not decrease with tap water. In contrast, there is a significant decrease in the amount of SAR with the cathode water of the present invention.
The pH of tap water was 5.8 ~ 8.6, and the oxidation-reduction potential (ORP) was +200 mV ~ +700 mV.
Mode 1 The values of the pH and oxidation-reduction potential (ORP) values of the generated water are shown in Table 1 when electrolyzed (current application time of 0.5 - 5 seconds) under various electrolytic currents (A) (generally expressed by current density (mA/cm2)). The current density is shown per one pair of electrodes (two) and diaphragm (one). From these experiments, it was found that the current density is preferably 0.16 mA/cm2 ~ 3.2 mA/cm2, particularly 0.224 mA/cm2 -1.6 mA/cm2.
Table 1 Electrolytic Current Current (A) Density pH ORP (mV) (mA/cm2) 0.3 1.0 8.9 -43 1.0 3.2 9.7 -142 1.5 4.9 10.1 -188 2.0 6.5 10.4 -210 Mode 2 An experiment was carried out to examine the efficacy of boiling the cathode water, obtained as described above, in disinfecting the cathode water by killing bacteria therein. It was found that cathode water subjected to boiling does not lose the capacity to abolish SAR.
Figure 1 is a diagram showing the concept of an electrolytic water generator for producing water for medical treatment according to the first embodiment of the present invention;
Figure 2 is a diagram showing the capacity of the water to abolish SAR
from blood for medical treatment according to the first embodiment using the blood of a 72-year-old male patient;
Figure 3 shows the capacity of the water to abolish SAR from blood for medical treatment according to the first embodiment using the blood of a 38-year-old mate patient;
Figure 4 shows the effect of the water of the present invention on the blood of a patient suffering from acute pancreatitis;
Figure 5 is a diagram showing the concept of a conventional dialysis apparatus for describing a dialysis apparatus according to the second embodiment of the present invention;
Figure 6 is a diagram showing the concept of the dialysis apparatus of the second embodiment;
Figure 7 shows the characterizing portion of the dialysis apparatus of the second embodiment in detail;
Figure 8 is a diagram showing the concept of a dialysis apparatus according to the third embodiment of the present invention.
First Embodiment Referring to Figure 1, an electrolytic water generator (HD-30) includes a cathode chamber 2 with a cathode 1 and an anode chamber 4 with an anode 3.
Cathode chamber 2 is separated from anode chamber 4 by a diaphragm 5. A
cathode liquid outlet pipe 6 from which cathode liquid is drawn out is connected to cathode chamber 2. A drain pipe 7 for discharging anode water outward is connected to anode chamber 4. A feed pipe 8 is connected to respective cathode and anode chambers 2 and 4 so that raw water such as tap water, ground water, or water from a well is supplied, which includes at least natrium, kalium, magnesium, and calcium.
Raw water such as tap water, ground water, or well water is supplied to cathode chamber 2 and anode chamber 4. A current within the range of 0.16 mA/cm2 5 ~ 3.2 mA/cmZ per two electrodes and one diaphragm is applied across cathode electrode 1 and anode electrode 3 for at least 0.5 seconds and not more than 5 seconds at room temperature (18°C ~ 22°C) to electrolyze the raw water. As a result, water for medical treatment, which is the cathode water, is obtained having the following properties. The oxidation-reduction potential (ORP) indicated in the present specification is measured using a platinum electrode by an ORP measuring apparatus (RM-12P) of Toa Denpa Co. Ltd.
pH 8.0 ~ 9.5 ORP (Oxidation-Reduction Potential): ~ 0 mV ~ 150 mV
Cathode water of various characteristics was produced to study the capacity of the water to abolish SAR from blood.
The graph of Figure 2 indicates the amount of SAR in a mixture of blood extracted from a 72-year-old male patient and the above-described cathode water over time. In the graph of Figure 2, time is plotted along the abscissa, and the amount of SAR is plotted along the ordinate. The curved line labeled "control" at the right side of the graph shows data when the above-described cathode water is not added.
The curved lines labeled 1 °, 2°, 3°, and 4° at the right side of the graph indicate data corresponding to the PBS test number.
Figure 3 shows the result of a similar test using blood extracted from a 38-year-old male patient.
Referring to Figures 2 and 3, it was found that cathode water having an oxidation-reduction potential (ORP) of -150 mV ~ 0 mV has the greatest potency to remove SAR.
Figure 4 shows the result of tracing the amount of SAR over time from a mixture of cathode water according to the present invention and blood extracted from a patient suffering from acute pancreatitis. The line labeled "TAP WATER"
shows data obtained from a mixture of tap water and the above-described blood, and the line labeled "REDUCED WATER" indicates data obtained from a mixture of cathode water of the present invention and blood. It is appreciated that the amount of SAR does not decrease with tap water. In contrast, there is a significant decrease in the amount of SAR with the cathode water of the present invention.
The pH of tap water was 5.8 ~ 8.6, and the oxidation-reduction potential (ORP) was +200 mV ~ +700 mV.
Mode 1 The values of the pH and oxidation-reduction potential (ORP) values of the generated water are shown in Table 1 when electrolyzed (current application time of 0.5 - 5 seconds) under various electrolytic currents (A) (generally expressed by current density (mA/cm2)). The current density is shown per one pair of electrodes (two) and diaphragm (one). From these experiments, it was found that the current density is preferably 0.16 mA/cm2 ~ 3.2 mA/cm2, particularly 0.224 mA/cm2 -1.6 mA/cm2.
Table 1 Electrolytic Current Current (A) Density pH ORP (mV) (mA/cm2) 0.3 1.0 8.9 -43 1.0 3.2 9.7 -142 1.5 4.9 10.1 -188 2.0 6.5 10.4 -210 Mode 2 An experiment was carried out to examine the efficacy of boiling the cathode water, obtained as described above, in disinfecting the cathode water by killing bacteria therein. It was found that cathode water subjected to boiling does not lose the capacity to abolish SAR.
Specifically, two types of electrolytic water having oxidation-reduction potentials of 0 mV and -150 mV were boiled. The boiling state was maintained for five minutes, and then cooling occurred for twenty minutes. The respective measured values of pH and ORP are shown in the following Tables 2 and 3.
Table 2 shows the data measured at Kochi City using the water of Kochi City. Table 3 shows the data measured at Kyoto City using the water of Kyoto City.
It was found that sterile water for medical treatment having an oxidation-reduction potential measured value within the range of -68 mV ~ +55 mV is obtained by boiling the cathode water.
Table 2 Before Boiling After Boiling pH 9.26 9.64 ORP OmV +55 mV
pH 11.2 10.7 ORP -150 mV -33 mV
Table 3 Before Boiling After Boiling pH 8.7 9.0 ORP -10 mV +21 mV
pH 9.8 9.9 ORP -172 mV -68 mV
The cathode water (before and after boiling) obtained in the above-described manner was stable for more than 80 hours. It can be preserved without degradation of its properties for about one year if sealed.
Table 2 shows the data measured at Kochi City using the water of Kochi City. Table 3 shows the data measured at Kyoto City using the water of Kyoto City.
It was found that sterile water for medical treatment having an oxidation-reduction potential measured value within the range of -68 mV ~ +55 mV is obtained by boiling the cathode water.
Table 2 Before Boiling After Boiling pH 9.26 9.64 ORP OmV +55 mV
pH 11.2 10.7 ORP -150 mV -33 mV
Table 3 Before Boiling After Boiling pH 8.7 9.0 ORP -10 mV +21 mV
pH 9.8 9.9 ORP -172 mV -68 mV
The cathode water (before and after boiling) obtained in the above-described manner was stable for more than 80 hours. It can be preserved without degradation of its properties for about one year if sealed.
Second Embodiment The second embodiment of the present invention relates to a dialysis apparatus improved so that cathode water having the above-described properties can be used as dialysis liquid.
First, a conventional dialysis apparatus will be described with reference to Figure 5.
Tap water (raw water) is passed through a precipitation prefilter 1 to remove particles and is then fed to a water-softening apparatus 2 to soften the water.
Then, chlorin ~ chloramine ~ endotoxin is removed by an active carbon filter apparatus 3. The water is then passed through a UV germicidal lamp 4 and then fed to a reverse osmosis apparatus 5. Only approximately 1/2 of the water fed into reverse osmosis apparatus 5 under pressurization passes through. The remaining half is processed as drainage. The water passed through is sterile purified water which is then stored in an RO water tank 6. The water is sterilized with a UV
germicidal lamp 7 and then conducted through a milli pore filter 8 to be fed into a dialysis liquid supply apparatus 9. Here, the processed water is mixed with an undiluted solution of sodium hydrogen carbonate and an undiluted electrolyte solution at a predetermined ratio, and passed through a dearator apparatus to be supplied to a human body 10 as dialysis liquid.
Hemodialysis carried out by a dialysis apparatus is a treatment involving substance exchange of the patient's intracorporeal-circulated blood and dialysis liquid (one type of electrolytic liquid) in a dialyzator via a membrane to remove and supply solute in the blood and to remove excessive water. A patient suffering from chronic renal insufficiency is subjected to hemodialysis approximately 3 times a week, each time taking about 4 hours. Since the flow rate of the dialysis liquid supplied to the dialyzator is normally 500 m~/minutes, the amount of dialysis liquid used in one treatment is 500 m~ x 240 minutes = 120,000 m~ = 120P per patient. Since this treatment of hemodialysis requires a great amount of water, the content of the water used in hemodialysis affects the patient greatly. The present embodiment is directed to this fact, and relates to utilizing the above-described cathode water of particular composition in a dialysis apparatus.
First, a conventional dialysis apparatus will be described with reference to Figure 5.
Tap water (raw water) is passed through a precipitation prefilter 1 to remove particles and is then fed to a water-softening apparatus 2 to soften the water.
Then, chlorin ~ chloramine ~ endotoxin is removed by an active carbon filter apparatus 3. The water is then passed through a UV germicidal lamp 4 and then fed to a reverse osmosis apparatus 5. Only approximately 1/2 of the water fed into reverse osmosis apparatus 5 under pressurization passes through. The remaining half is processed as drainage. The water passed through is sterile purified water which is then stored in an RO water tank 6. The water is sterilized with a UV
germicidal lamp 7 and then conducted through a milli pore filter 8 to be fed into a dialysis liquid supply apparatus 9. Here, the processed water is mixed with an undiluted solution of sodium hydrogen carbonate and an undiluted electrolyte solution at a predetermined ratio, and passed through a dearator apparatus to be supplied to a human body 10 as dialysis liquid.
Hemodialysis carried out by a dialysis apparatus is a treatment involving substance exchange of the patient's intracorporeal-circulated blood and dialysis liquid (one type of electrolytic liquid) in a dialyzator via a membrane to remove and supply solute in the blood and to remove excessive water. A patient suffering from chronic renal insufficiency is subjected to hemodialysis approximately 3 times a week, each time taking about 4 hours. Since the flow rate of the dialysis liquid supplied to the dialyzator is normally 500 m~/minutes, the amount of dialysis liquid used in one treatment is 500 m~ x 240 minutes = 120,000 m~ = 120P per patient. Since this treatment of hemodialysis requires a great amount of water, the content of the water used in hemodialysis affects the patient greatly. The present embodiment is directed to this fact, and relates to utilizing the above-described cathode water of particular composition in a dialysis apparatus.
Figure 6 shows a dialysis apparatus according to the second embodiment of the present invention.
The dialysis apparatus of the second embodiment differs from the conventional dialysis apparratus of Figure 5 in that an electrolytic water generation apparatus a and an electrolytic water reservoir tank b are provided between UV
germicidal tamp 4 and reverse osmosis apparatus 5.
Tap water (raw water) is passed through precipitation prefilter 1 to have particles removed. Next, the water is softened by water-softening apparatus 2 to be supplied to active carbon filtering apparatus 3 to have chlorin ~ chloramine ~ endotoxin removed. Then, thie water is passed through UV germicidal lamp 4.
The sterilized water is fed to electrolytic water generation apparatus a to be electrolyzed.
Cathode water obtained by electrolysis is stored in electrolytic water reservoir tank b and fed to reverse osmosis apparatus 5. Here, half of the fed water passes through, and the remainin!a water that does not pass through flows through a feedback conduit 11 provided between reverse osmosis apparatus 5 and electrolytic wafer reservoir tank b to be returned to electrolytic water reservoir tank b by a pump P. The water passed through reverse osmosis apparatus 5i is substantially purified water with no bacteria. This water is stored in RO water tank 6 and then sent to dialysis liquid supply apparatus 9 via UV germicidal lamp 7 and milli pore filter 8. The processed water is combined with an undiluted solution of sodium hydrogen carbonate and an undiluted electrolyte solution at a predetermined ratio. The mixture is passed through a deaerator to be supplied to human body 10 as dialysis liquid.
Figure 7 shows the details of active carbon filter apparatus 3, electrolytic water generation apparatus (r-ifJ-30)a, electrolytic water reservoir tank b, and reverse osmosis apparatus 5 shown in F figure 6.
The present invention is not limited to four electrolytic water' generators (HD-30) shown in the present embodiment.
Also, the invention is not limited to the present dialysis apparatus having an electrolytic liquid reservoir tank provided. An electrolytic water reservoir tank is not necessarily required, and water can be supplied directly to reverse osmosis apparatus 5 from electrolytic; water generation apparatus a.
** TOTAL PAGE.02 **
In the present embodiment, a reverse osmosis filtering apparatus is shown as an apparatus for filtering cathode water. Alternatively, cathode water can be filtered with a hollow fiber membrane filter.
According to the dialysis apparatus of the second embodiment, SAR in 5 the blood of a patient can be removed in addition to the effect of a conventional hemodialysis treatment. The frequency of dialysis for a patient suffering from chronic renal insufficiency is thus reduced, and the time required for the treatment is decreased. There is an advantage that the length of time the patient spends on the dialysis apparatus can be shortened.
The dialysis apparatus of the second embodiment differs from the conventional dialysis apparratus of Figure 5 in that an electrolytic water generation apparatus a and an electrolytic water reservoir tank b are provided between UV
germicidal tamp 4 and reverse osmosis apparatus 5.
Tap water (raw water) is passed through precipitation prefilter 1 to have particles removed. Next, the water is softened by water-softening apparatus 2 to be supplied to active carbon filtering apparatus 3 to have chlorin ~ chloramine ~ endotoxin removed. Then, thie water is passed through UV germicidal lamp 4.
The sterilized water is fed to electrolytic water generation apparatus a to be electrolyzed.
Cathode water obtained by electrolysis is stored in electrolytic water reservoir tank b and fed to reverse osmosis apparatus 5. Here, half of the fed water passes through, and the remainin!a water that does not pass through flows through a feedback conduit 11 provided between reverse osmosis apparatus 5 and electrolytic wafer reservoir tank b to be returned to electrolytic water reservoir tank b by a pump P. The water passed through reverse osmosis apparatus 5i is substantially purified water with no bacteria. This water is stored in RO water tank 6 and then sent to dialysis liquid supply apparatus 9 via UV germicidal lamp 7 and milli pore filter 8. The processed water is combined with an undiluted solution of sodium hydrogen carbonate and an undiluted electrolyte solution at a predetermined ratio. The mixture is passed through a deaerator to be supplied to human body 10 as dialysis liquid.
Figure 7 shows the details of active carbon filter apparatus 3, electrolytic water generation apparatus (r-ifJ-30)a, electrolytic water reservoir tank b, and reverse osmosis apparatus 5 shown in F figure 6.
The present invention is not limited to four electrolytic water' generators (HD-30) shown in the present embodiment.
Also, the invention is not limited to the present dialysis apparatus having an electrolytic liquid reservoir tank provided. An electrolytic water reservoir tank is not necessarily required, and water can be supplied directly to reverse osmosis apparatus 5 from electrolytic; water generation apparatus a.
** TOTAL PAGE.02 **
In the present embodiment, a reverse osmosis filtering apparatus is shown as an apparatus for filtering cathode water. Alternatively, cathode water can be filtered with a hollow fiber membrane filter.
According to the dialysis apparatus of the second embodiment, SAR in 5 the blood of a patient can be removed in addition to the effect of a conventional hemodialysis treatment. The frequency of dialysis for a patient suffering from chronic renal insufficiency is thus reduced, and the time required for the treatment is decreased. There is an advantage that the length of time the patient spends on the dialysis apparatus can be shortened.
10 Third Embodiment A dialysis apparatus according to a third embodiment of the present invention, shown in Figure 8, is similar to the dialysis apparatus of Figure 6 except for the following points. Like or corresponding components have the same reference characters allotted, and their description will not be repeated.
More specifically, the dialysis apparatus according to the third embodiment of the present invention includes a boiler 12 which serves as boiling means, and does not include sterilizing means such as a UV germicidal lamp, a reverse osmosis apparatus, an RO liquid tank, or a milli pore filter. Water introduced from electrolytic water reservoir tank b to boiler 12 is boiled and sterilized. Then, the sterile water is provided to dialysis liquid supply apparatus 9 to be applied to patient 10. By substituting sterilization means with such a boiler 12, the cost and burden of maintenance are relieved in contrast to the case where sterilization means such as a UV germicidal lamp is used.
The present invention is not limited to the three above-described embodiments in which the water for medical treatment of the above-described properties is used for cleaning blood, and can be used for the preparation of Ringer's solution and to prepare sterile water used for surgery.
Although the present invention has been described and illustrated in detail, it is clearly understood that the same is by way of illustration and example only and is not to be taken by way of limitation, the spirit and scope of the present invention being limited only by the terms of the appended claims.
More specifically, the dialysis apparatus according to the third embodiment of the present invention includes a boiler 12 which serves as boiling means, and does not include sterilizing means such as a UV germicidal lamp, a reverse osmosis apparatus, an RO liquid tank, or a milli pore filter. Water introduced from electrolytic water reservoir tank b to boiler 12 is boiled and sterilized. Then, the sterile water is provided to dialysis liquid supply apparatus 9 to be applied to patient 10. By substituting sterilization means with such a boiler 12, the cost and burden of maintenance are relieved in contrast to the case where sterilization means such as a UV germicidal lamp is used.
The present invention is not limited to the three above-described embodiments in which the water for medical treatment of the above-described properties is used for cleaning blood, and can be used for the preparation of Ringer's solution and to prepare sterile water used for surgery.
Although the present invention has been described and illustrated in detail, it is clearly understood that the same is by way of illustration and example only and is not to be taken by way of limitation, the spirit and scope of the present invention being limited only by the terms of the appended claims.
Claims (4)
1. A dialysis apparatus comprising:
electrolytic water generation means for electrolyzing water, boiling means for boiling cathode water sent from said electrolytic water generation means, and dialysis liquid supply means for supplying the cathode water introduced from said boiling means as dialysis liquid.
electrolytic water generation means for electrolyzing water, boiling means for boiling cathode water sent from said electrolytic water generation means, and dialysis liquid supply means for supplying the cathode water introduced from said boiling means as dialysis liquid.
2. The dialysis apparatus according to claim 1, wherein said cathode water includes water having an oxidation-reduction potential value within a range of -150 mV ~ 0 mV measured using a platinum electrode.
3. The dialysis apparatus according to claim 1 or 2, wherein said cathode water includes electrons and protons.
4. The dialysis apparatus according to claim 3, wherein said cathode water includes a sufficient amount of electrons and protons to change O2- into H2O by the reaction mechanism:
O2-~ + e- + 2H+ .fwdarw. H2O2 H2O2 + e- .fwdarw. HO~ + HO-HO~+ e- + H+ .fwdarw.H2O
O2-~ + e- + 2H+ .fwdarw. H2O2 H2O2 + e- .fwdarw. HO~ + HO-HO~+ e- + H+ .fwdarw.H2O
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17190295 | 1995-07-07 | ||
| JP7-171902 | 1995-07-07 | ||
| JP15564796A JP3193295B2 (en) | 1995-07-07 | 1996-06-17 | Dialysis machine |
| JP8-155647 | 1996-06-17 | ||
| CA002303676A CA2303676C (en) | 1995-07-07 | 1996-07-04 | Water for medical treatment, production method thereof, and dialysis apparatus using water for medical treatment as dialysis liquid |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002303676A Division CA2303676C (en) | 1995-07-07 | 1996-07-04 | Water for medical treatment, production method thereof, and dialysis apparatus using water for medical treatment as dialysis liquid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2406476A1 CA2406476A1 (en) | 1997-01-08 |
| CA2406476C true CA2406476C (en) | 2004-04-13 |
Family
ID=27171208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002406476A Expired - Lifetime CA2406476C (en) | 1995-07-07 | 1996-07-04 | Water for medical treatment, production method thereof, and dialysis apparatus using water for medical treatment as dialysis liquid |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2406476C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4004523B1 (en) * | 2006-04-21 | 2007-11-07 | 株式会社日本トリム | Dialysate preparation water, dialysate using the same, dialysate production method and dialyzer |
-
1996
- 1996-07-04 CA CA002406476A patent/CA2406476C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2406476A1 (en) | 1997-01-08 |
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| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20160704 |