CA2399834C - Preparation of dialkylpyridylboranes - Google Patents
Preparation of dialkylpyridylboranes Download PDFInfo
- Publication number
- CA2399834C CA2399834C CA002399834A CA2399834A CA2399834C CA 2399834 C CA2399834 C CA 2399834C CA 002399834 A CA002399834 A CA 002399834A CA 2399834 A CA2399834 A CA 2399834A CA 2399834 C CA2399834 C CA 2399834C
- Authority
- CA
- Canada
- Prior art keywords
- reagent
- c10alkyl
- alkoxydialkylborane
- grignard
- pyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31518301P | 2001-08-27 | 2001-08-27 | |
| US60/315,183 | 2001-08-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2399834A1 CA2399834A1 (en) | 2003-02-27 |
| CA2399834C true CA2399834C (en) | 2006-08-22 |
Family
ID=23223262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002399834A Expired - Fee Related CA2399834C (en) | 2001-08-27 | 2002-08-23 | Preparation of dialkylpyridylboranes |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6570017B2 (https=) |
| EP (1) | EP1288217B1 (https=) |
| JP (1) | JP2003096084A (https=) |
| KR (1) | KR20030019112A (https=) |
| CN (1) | CN1401649A (https=) |
| AT (1) | ATE321766T1 (https=) |
| BR (1) | BR0203371A (https=) |
| CA (1) | CA2399834C (https=) |
| CZ (1) | CZ20022642A3 (https=) |
| DE (1) | DE60210224T2 (https=) |
| ES (1) | ES2256416T3 (https=) |
| HU (1) | HUP0202868A3 (https=) |
| IL (1) | IL151379A0 (https=) |
| MX (1) | MXPA02008364A (https=) |
| PL (1) | PL355706A1 (https=) |
| RU (1) | RU2002122947A (https=) |
| YU (1) | YU59502A (https=) |
| ZA (1) | ZA200206778B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2576570A1 (en) * | 2010-05-26 | 2013-04-10 | Boehringer Ingelheim International GmbH | 2-oxo-1,2-dihydropyridin-4-ylboronic acid derivatives |
| CN103483366B (zh) * | 2013-09-05 | 2017-02-08 | 润泽制药(苏州)有限公司 | 甲氧基二乙基硼烷的制备方法 |
| EP3377475A4 (en) * | 2015-11-17 | 2019-04-10 | Dow Agrosciences Llc | 4 - ((6-2- (2,4-difluorophenyl) -1,1-difluoro-2-hydroxy-3- (1H-1,2,4-triazol-1-YL) PROPYL) PYRIDINE-3-YL ) OXY) BENZONITRIL AND METHOD OF PREPARING THEREOF |
| CN117402184B (zh) * | 2023-12-15 | 2024-04-26 | 山东国邦药业有限公司 | 一种二乙基甲氧基硼烷的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2961831D1 (en) * | 1978-11-07 | 1982-02-25 | Ici Plc | Alkylborane complexes with aromatic amines, solutions thereof for use as hydroborating and reducing agents, and processes for their manufacture |
| GB8304613D0 (en) * | 1983-02-18 | 1983-03-23 | Ici Plc | Chemical process |
| DE4320432A1 (de) * | 1993-06-21 | 1994-12-22 | Bayer Ag | Substituierte Mono- und Bipyridylmethylderivate |
| US5486534A (en) * | 1994-07-21 | 1996-01-23 | G. D. Searle & Co. | 3,4-substituted pyrazoles for the treatment of inflammation |
| HRP20000724A2 (en) * | 1998-05-05 | 2001-06-30 | Hoffmann La Roche | Pyrazole derivatives as p-38 map kinase inhibitors |
-
2002
- 2002-07-31 CZ CZ20022642A patent/CZ20022642A3/cs unknown
- 2002-08-09 YU YU59502A patent/YU59502A/sh unknown
- 2002-08-15 DE DE60210224T patent/DE60210224T2/de not_active Expired - Fee Related
- 2002-08-15 AT AT02255717T patent/ATE321766T1/de not_active IP Right Cessation
- 2002-08-15 EP EP02255717A patent/EP1288217B1/en not_active Expired - Lifetime
- 2002-08-15 ES ES02255717T patent/ES2256416T3/es not_active Expired - Lifetime
- 2002-08-21 IL IL15137902A patent/IL151379A0/xx unknown
- 2002-08-23 ZA ZA200206778A patent/ZA200206778B/xx unknown
- 2002-08-23 US US10/226,429 patent/US6570017B2/en not_active Expired - Fee Related
- 2002-08-23 CA CA002399834A patent/CA2399834C/en not_active Expired - Fee Related
- 2002-08-23 BR BR0203371-2A patent/BR0203371A/pt not_active IP Right Cessation
- 2002-08-23 JP JP2002243438A patent/JP2003096084A/ja active Pending
- 2002-08-23 CN CN02142212A patent/CN1401649A/zh active Pending
- 2002-08-26 PL PL02355706A patent/PL355706A1/xx unknown
- 2002-08-26 MX MXPA02008364A patent/MXPA02008364A/es active IP Right Grant
- 2002-08-26 HU HU0202868A patent/HUP0202868A3/hu unknown
- 2002-08-26 KR KR1020020050579A patent/KR20030019112A/ko not_active Ceased
- 2002-08-26 RU RU2002122947/04A patent/RU2002122947A/ru unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ20022642A3 (cs) | 2003-09-17 |
| HUP0202868A3 (en) | 2004-04-28 |
| JP2003096084A (ja) | 2003-04-03 |
| ZA200206778B (en) | 2004-02-23 |
| PL355706A1 (en) | 2003-03-10 |
| ATE321766T1 (de) | 2006-04-15 |
| RU2002122947A (ru) | 2004-03-10 |
| HUP0202868A2 (hu) | 2003-06-28 |
| EP1288217B1 (en) | 2006-03-29 |
| BR0203371A (pt) | 2003-05-27 |
| EP1288217A3 (en) | 2003-09-17 |
| HU0202868D0 (https=) | 2002-10-28 |
| CN1401649A (zh) | 2003-03-12 |
| IL151379A0 (en) | 2003-04-10 |
| MXPA02008364A (es) | 2003-03-04 |
| ES2256416T3 (es) | 2006-07-16 |
| DE60210224D1 (de) | 2006-05-18 |
| KR20030019112A (ko) | 2003-03-06 |
| US20030083312A1 (en) | 2003-05-01 |
| YU59502A (sh) | 2004-12-31 |
| US6570017B2 (en) | 2003-05-27 |
| CA2399834A1 (en) | 2003-02-27 |
| DE60210224T2 (de) | 2007-01-11 |
| EP1288217A2 (en) | 2003-03-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RS59502B1 (sr) | Postupak za kontrolu brzina promene snage kojim se minimizuju potrebe za skladištenjem energije u postrojenjima za povremenu proizvodnju električne energije | |
| Roesler et al. | Synthesis, structural characterization and reactivity of the amino borane 1-(NPh2)-2-[B (C6F5) 2] C6H4 | |
| Landmann et al. | Deprotonation of a hydridoborate anion | |
| Fang et al. | Synthesis, Structure, and Reactivity of Hydridoiridium Complexes Bearing a Pincer‐Type PSiP Ligand | |
| Ainscough et al. | Hexafluorosilicate coordination to the antitumour copper (II) salicylaldehyde benzoylhydrazone (H2L) system: single-crystal X-ray structure of [{Cu (HL) H2O} 2SiF6]· 2H2O | |
| CN1056372C (zh) | 噻唑烷二酮衍生物,它们的制备方法和用途 | |
| Gibson et al. | Synthesis and structural characterisation of aluminium imino-amide and pyridyl-amide complexes: Bulky monoanionic N, N chelate ligands via methyl group transfer | |
| CA2399834C (en) | Preparation of dialkylpyridylboranes | |
| Hiroi et al. | N-Phosphano nitrogen-containing five-membered aromatic chiral α-sulfoxides as new chiral ligands in asymmetric palladium-catalyzed allylic alkylation: stereoelectronic effects of the substituents on the aromatic rings | |
| Ivchenko et al. | A convenient approach for the synthesis of 2, 6-diformyl-and 2, 6-diacetylpyridines | |
| Hardman et al. | Unusual structures of lithium terphenyl derivatives | |
| Shi et al. | Chiral phosphine ligands derived from sugars. 3. Syntheses, structures, and spectroscopic properties of gold (I) complexes with chiral phosphines from glucose. X-ray structures of [Au (2-MBPA) Cl] and [Au (3-MBPA)(2-pyS)] | |
| JPS61109767A (ja) | オキシンドール抗炎症剤 | |
| Lomelı́ et al. | An indium (II)-indium (II) compound with intramolecular donor-acceptor bonds | |
| Ball et al. | The mechanism of lithiation and nitrile insertion reactions of β-methylazines: evidence from the structure of 3-C5H4NCH C (Ph) N (H) C (Ph) NLi· PMDETA | |
| Gorden et al. | The unusual reaction of Ga (C5Me5) 3 with a nucleophilic carbene | |
| Kobayashi et al. | Installation of the imidazole ring on chiral substrates via allylic substitution | |
| HK1050534A (en) | Preparation of dialkylpyridylboranes | |
| Arvanitis et al. | CRF Ligands via suzuki and negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine | |
| Soderquist et al. | Markovnikov vinylborinates from 9-oxa-10-borabicyclo [3.3. 2] decanes | |
| JPH0373548B2 (https=) | ||
| Zabalov et al. | Transition metal complexes with heterocyclic analogs of fluorene. 1. Synthesis, structures, and haptotropic rearrangements of tricarbonylchromium complexes of dibenzothiophene | |
| Atwood et al. | Unusual intramolecular hydrogen bonding in Cy2GaBrNH2Ph. The first structurally characterized dialkyl gallium halide primary amine adduct | |
| Murata et al. | Hydrogen-bonded networks of 2, 2′-substituted 4, 4′-biimidazoles: New ligands for the assembled metal complexes | |
| Belov et al. | Novel sandwich complexes of zirconium [C9H5 (SiMe3) 2](C5Me4R) ZrCl2 (R= CH3, CH2CH2NMe2): Synthesis and reduction behavior |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |