CA2392474A1 - Reseaux de sondes d'acides nucleiques - Google Patents

Reseaux de sondes d'acides nucleiques Download PDF

Info

Publication number
CA2392474A1
CA2392474A1 CA002392474A CA2392474A CA2392474A1 CA 2392474 A1 CA2392474 A1 CA 2392474A1 CA 002392474 A CA002392474 A CA 002392474A CA 2392474 A CA2392474 A CA 2392474A CA 2392474 A1 CA2392474 A1 CA 2392474A1
Authority
CA
Canada
Prior art keywords
nucleic acid
region
target nucleic
anchor
array
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002392474A
Other languages
English (en)
Inventor
Jonathan M. Rothberg
Joel S. Bader
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
454 Life Science Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2392474A1 publication Critical patent/CA2392474A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Abstract

L'invention concerne des réseaux de sondes d'acides nucléiques et des méthodes d'identification et de séquencage des acides nucléiques dans une population d'acides nucléiques à l'aide de ces réseaux.
CA002392474A 1999-11-26 2000-11-27 Reseaux de sondes d'acides nucleiques Abandoned CA2392474A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44940299A 1999-11-26 1999-11-26
US09/449,402 1999-11-26
PCT/US2000/032131 WO2001038580A2 (fr) 1999-11-26 2000-11-27 Reseaux de sondes d'acides nucleiques

Publications (1)

Publication Number Publication Date
CA2392474A1 true CA2392474A1 (fr) 2001-05-31

Family

ID=23784034

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002392474A Abandoned CA2392474A1 (fr) 1999-11-26 2000-11-27 Reseaux de sondes d'acides nucleiques

Country Status (5)

Country Link
EP (1) EP1234058A2 (fr)
JP (1) JP2003515149A (fr)
AU (1) AU783841B2 (fr)
CA (1) CA2392474A1 (fr)
WO (1) WO2001038580A2 (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2378245A (en) * 2001-08-03 2003-02-05 Mats Nilsson Nucleic acid amplification method
US9388459B2 (en) * 2002-06-17 2016-07-12 Affymetrix, Inc. Methods for genotyping
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US6977153B2 (en) * 2002-12-31 2005-12-20 Qiagen Gmbh Rolling circle amplification of RNA
EP1598427A1 (fr) * 2004-05-17 2005-11-23 Charité - Universitätsmedizin Berlin Méthode pour l'amplification d'acide nucléique cible
EP2290071B1 (fr) 2004-05-28 2014-12-31 Asuragen, Inc. Procédés et compositions impliquant du microARN
CA2850323A1 (fr) 2004-11-12 2006-12-28 Asuragen, Inc. Procedes et compositions comprenant des molecules de micro-arn et des molecules d'inhibiteur de micro-arn
AU2006259565B2 (en) 2005-06-15 2011-01-06 Complete Genomics, Inc. Single molecule arrays for genetic and chemical analysis
EP1762627A1 (fr) 2005-09-09 2007-03-14 Qiagen GmbH Procédé pour l'activation d'acides nucléiques pour effectuer une réaction d'une polymérase
US11306351B2 (en) 2005-12-21 2022-04-19 Affymetrix, Inc. Methods for genotyping
EP2487240B1 (fr) 2006-09-19 2016-11-16 Interpace Diagnostics, LLC Micro ARN différemment exprimés dans des maladies pancréatiques et leurs utilisations
WO2008036776A2 (fr) 2006-09-19 2008-03-27 Asuragen, Inc. Gènes régulés mir-15, mir-26, mir -31,mir -145, mir-147, mir-188, mir-215, mir-216 mir-331, mmu-mir-292-3p et voies de signalisation utiles comme cibles dans une intervention thérapeutique
KR20100037590A (ko) 2007-06-08 2010-04-09 바이오겐 아이덱 엠에이 인코포레이티드 항 ｔｎｆ 반응 또는 무반응을 예측하기 위한 바이오마커
JP5020734B2 (ja) * 2007-07-31 2012-09-05 株式会社日立ハイテクノロジーズ 核酸解析方法及び装置
EP2285960B1 (fr) 2008-05-08 2015-07-08 Asuragen, INC. Compositions et procédés liés à la modulation de miarn-184 de néovascularisation ou d angiogenèse
US8486630B2 (en) 2008-11-07 2013-07-16 Industrial Technology Research Institute Methods for accurate sequence data and modified base position determination
GB0921264D0 (en) 2009-12-03 2010-01-20 Olink Genomics Ab Method for amplification of target nucleic acid
WO2011100503A1 (fr) 2010-02-11 2011-08-18 Dana Farber Cancer Institute, Inc. Procédés pour prédire la probabilité de réponse à un traitement
ES2631458T3 (es) 2010-03-04 2017-08-31 Interna Technologies B.V. Molécula de ARNmi definida por su fuente y sus usos terapéuticos en el cáncer asociado a la EMT
NZ719520A (en) 2010-07-06 2017-07-28 Int Tech Bv Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway
EP2772550B1 (fr) 2010-11-17 2017-03-29 Interpace Diagnostics, LLC Micro-ARN comme biomarqueurs pour différencier des néoplasmes de thyroïde bénins et malins
EP2474617A1 (fr) 2011-01-11 2012-07-11 InteRNA Technologies BV MIR pour traiter une nouvelle angiogenèse
US20140057295A1 (en) 2011-02-28 2014-02-27 Barbara J. Stegmann Anti-mullerian hormone changes in pregnancy and prediction of adverse pregnancy outcomes and gender
CN102732598B (zh) * 2011-04-11 2017-03-01 陈先锋 一种全基因组dna序列拼接测序方法
EP2718866B1 (fr) * 2011-06-07 2020-09-09 Koninklijke Philips N.V. Fourniture de données de séquence nucléotidique
US9644241B2 (en) 2011-09-13 2017-05-09 Interpace Diagnostics, Llc Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease
WO2013063519A1 (fr) 2011-10-26 2013-05-02 Asuragen, Inc. Procédés et compositions faisant intervenir des taux d'expression de miarn pour distinguer des kystes pancréatiques
WO2013063544A1 (fr) 2011-10-27 2013-05-02 Asuragen, Inc. Miarn en tant que biomarqueurs de diagnostic pour distinguer des tumeurs thyroïdiennes bénignes de malignes
US20150152499A1 (en) 2012-07-03 2015-06-04 Interna Technologies B.V. Diagnostic portfolio and its uses
WO2014055117A1 (fr) 2012-10-04 2014-04-10 Asuragen, Inc. Micro-arn diagnostiques utilisés dans le diagnostic différentiel de lésions kystiques pancréatiques de découverte fortuite
KR101984700B1 (ko) * 2012-11-19 2019-05-31 삼성전자주식회사 폴리뉴클레오티드 및 그의 용도
US9944992B2 (en) 2013-03-15 2018-04-17 The University Of Chicago Methods and compositions related to T-cell activity
US9868992B2 (en) 2013-03-15 2018-01-16 Baylor Research Institute Tissue and blood-based miRNA biomarkers for the diagnosis, prognosis and metastasis-predictive potential in colorectal cancer
CA2905949A1 (fr) 2013-03-15 2014-09-25 Baylor Research Institute Marqueurs d'une neoplasie colorectale associee a la colite ulcereuse (uc)
WO2015089333A1 (fr) * 2013-12-11 2015-06-18 Accuragen, Inc. Compositions et procédés permettant de détecter des variants de séquence rares
US11286519B2 (en) 2013-12-11 2022-03-29 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
US11859246B2 (en) * 2013-12-11 2024-01-02 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
WO2016156576A1 (fr) 2015-04-02 2016-10-06 Hmnc Value Gmbh Méthode de traitement utilisant les prédicteurs génétiques d'une réponse à un traitement basé sur des antagonistes du crhr1
CN114807323A (zh) 2015-10-09 2022-07-29 安可济控股有限公司 用于富集扩增产物的方法及组合物
WO2017135383A1 (fr) * 2016-02-03 2017-08-10 国立大学法人豊橋技術科学大学 Pseudo polynucléotide cyclique double brin, et inhibiteur d'expression de gène
CN109511265B (zh) 2016-05-16 2023-07-14 安可济控股有限公司 通过链鉴定改进测序的方法
CA3033749A1 (fr) 2016-08-15 2018-02-22 Accuragen Holdings Limited Compositions et procedes permettant de detecter des variants de sequences rares
EP3541950A4 (fr) * 2016-11-16 2020-06-03 Progenity, Inc. Dosage multimodal pour la détection d'aberrations de l'acide nucléique
WO2019086603A1 (fr) 2017-11-03 2019-05-09 Interna Technologies B.V. Molécule de micro-arn, équivalent, antagomir, ou source de cette molécule pour le traitement et/ou le diagnostic d'une affection et/ou d'une maladie associée à une déficience neuronale ou pour la (ré)génération neuronale
US11203782B2 (en) 2018-03-29 2021-12-21 Accuragen Holdings Limited Compositions and methods comprising asymmetric barcoding
EP3952849A4 (fr) 2019-04-12 2023-03-01 The Regents Of The University Of California Compositions et procédés d'augmentation de la masse musculaire et du métabolisme oxydatif
WO2024028794A1 (fr) 2022-08-02 2024-02-08 Temple Therapeutics BV Méthodes de traitement de troubles de l'endomètre et de l'hyperprolifération ovarienne

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503980A (en) * 1992-11-06 1996-04-02 Trustees Of Boston University Positional sequencing by hybridization
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
SE9701783D0 (sv) * 1997-05-14 1997-05-14 Marek Kwiatkowski In situ synthesis of oligonucleotides of inverse orientation
AU3027699A (en) * 1998-02-02 1999-08-16 Amersham Pharmacia Biotech Ab Nucleic acid analysis method
JP4493844B2 (ja) * 1998-03-25 2010-06-30 ランデグレン、ウルフ 錠型（ｐａｄｌｏｃｋ）プローブのローリングサークル複製
WO1999053102A1 (fr) * 1998-04-16 1999-10-21 Packard Bioscience Company Analyse de sequence de polynucleotides

Also Published As

Publication number Publication date
AU1792701A (en) 2001-06-04
JP2003515149A (ja) 2003-04-22
WO2001038580A2 (fr) 2001-05-31
WO2001038580A9 (fr) 2002-12-05
WO2001038580A3 (fr) 2002-04-25
EP1234058A2 (fr) 2002-08-28
AU783841B2 (en) 2005-12-15

Similar Documents

Publication Publication Date Title
AU783841B2 (en) Nucleic acid probe arrays
JP5957039B2 (ja) 全ゲノム増幅および遺伝型決定のための方法および組成物
US6355431B1 (en) Detection of nucleic acid amplification reactions using bead arrays
US6287778B1 (en) Allele detection using primer extension with sequence-coded identity tags
US20050074787A1 (en) Universal arrays
US7414115B2 (en) Length determination of nucleic acid repeat sequences by discontinuous primer extension
US20030175706A1 (en) Nucleic acid amplification methods
US7351532B2 (en) DNA sequence analysis
US20140038238A1 (en) Nucleic acid amplification methods
JP2007525963A (ja) 全ゲノム増幅および遺伝型決定のための方法および組成物
CA2374406A1 (fr) Analyse des variations de sequences polynucleotidiques par micro-echantillons
EP1723261A1 (fr) Detection d'un strp, tel que le syndrome de l'x fragile
CA2366112A1 (fr) Procede de sequencage direct d'acides nucleiques
KR20040068122A (ko) 공동 검색과 효소-매개된 탐지에 의한 다형성 좌위의 다중분석
WO2002050310A9 (fr) Detection d'adn et d'arn par amplification en cercle roulant
EP1917346A2 (fr) Compositions et procedes de motif de signal
US20040137484A1 (en) Nucleic acid amplification methods
US6638719B1 (en) Genotyping biallelic markers
US20090136916A1 (en) Methods and microarrays for detecting enteric viruses
US20100285970A1 (en) Methods of sequencing nucleic acids
JP5378724B2 (ja) 発現ｍＲＮＡ識別方法
WO2000009738A9 (fr) Analyse par cercles roulants d'une sequence polynucleotidique
US20040203005A1 (en) Dual hybridization of complex nucleic acid samples for sequencing and single-nucleotide polymorphism identification
Banér Genetic Analyses using Rolling Circle or PCR Amplified Padlock Probes

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued