SE9701783D0 - In situ synthesis of oligonucleotides of inverse orientation - Google Patents

In situ synthesis of oligonucleotides of inverse orientation

Info

Publication number
SE9701783D0
SE9701783D0 SE9701783A SE9701783A SE9701783D0 SE 9701783 D0 SE9701783 D0 SE 9701783D0 SE 9701783 A SE9701783 A SE 9701783A SE 9701783 A SE9701783 A SE 9701783A SE 9701783 D0 SE9701783 D0 SE 9701783D0
Authority
SE
Sweden
Prior art keywords
oligonucleotides
oligonucleotide
situ synthesis
inverse orientation
free
Prior art date
Application number
SE9701783A
Other languages
English (en)
Inventor
Marek Kwiatkowski
Ulf Landegren
Mats Nilsson
Original Assignee
Marek Kwiatkowski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marek Kwiatkowski filed Critical Marek Kwiatkowski
Priority to SE9701783A priority Critical patent/SE9701783D0/sv
Publication of SE9701783D0 publication Critical patent/SE9701783D0/sv
Priority to PCT/SE1998/000893 priority patent/WO1998051698A1/en
Priority to DE69835207T priority patent/DE69835207D1/de
Priority to CA002289204A priority patent/CA2289204A1/en
Priority to EP98923266A priority patent/EP0983288B1/en
Priority to JP54915198A priority patent/JP2001525821A/ja
Priority to AT98923266T priority patent/ATE332911T1/de
Priority to US09/423,742 priority patent/US6313284B1/en
Priority to US09/952,944 priority patent/US6790946B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SE9701783A 1997-05-14 1997-05-14 In situ synthesis of oligonucleotides of inverse orientation SE9701783D0 (sv)

Priority Applications (9)

Application Number Priority Date Filing Date Title
SE9701783A SE9701783D0 (sv) 1997-05-14 1997-05-14 In situ synthesis of oligonucleotides of inverse orientation
PCT/SE1998/000893 WO1998051698A1 (en) 1997-05-14 1998-05-14 Synthesis of oligonucleotides
DE69835207T DE69835207D1 (de) 1997-05-14 1998-05-14 Synthese von oligonukleotiden
CA002289204A CA2289204A1 (en) 1997-05-14 1998-05-14 Synthesis of oligonucleotides
EP98923266A EP0983288B1 (en) 1997-05-14 1998-05-14 Synthesis of oligonucleotides
JP54915198A JP2001525821A (ja) 1997-05-14 1998-05-14 オリゴヌクレオチドの合成
AT98923266T ATE332911T1 (de) 1997-05-14 1998-05-14 Synthese von oligonukleotiden
US09/423,742 US6313284B1 (en) 1997-05-14 1998-05-14 Solid phase synthesis
US09/952,944 US6790946B2 (en) 1997-05-14 2001-09-12 Synthesis of oligonucleotides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9701783A SE9701783D0 (sv) 1997-05-14 1997-05-14 In situ synthesis of oligonucleotides of inverse orientation

Publications (1)

Publication Number Publication Date
SE9701783D0 true SE9701783D0 (sv) 1997-05-14

Family

ID=20406926

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9701783A SE9701783D0 (sv) 1997-05-14 1997-05-14 In situ synthesis of oligonucleotides of inverse orientation

Country Status (8)

Country Link
US (2) US6313284B1 (sv)
EP (1) EP0983288B1 (sv)
JP (1) JP2001525821A (sv)
AT (1) ATE332911T1 (sv)
CA (1) CA2289204A1 (sv)
DE (1) DE69835207D1 (sv)
SE (1) SE9701783D0 (sv)
WO (1) WO1998051698A1 (sv)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9701783D0 (sv) * 1997-05-14 1997-05-14 Marek Kwiatkowski In situ synthesis of oligonucleotides of inverse orientation
US6309836B1 (en) 1999-10-05 2001-10-30 Marek Kwiatkowski Compounds for protecting hydroxyls and methods for their use
WO2001038580A2 (en) * 1999-11-26 2001-05-31 Curagen Corporation Nucleic acid probe arrays
WO2001092566A2 (de) * 2000-05-26 2001-12-06 Noxxon Pharma Ag Immobilisierte nukleinsäuren und verwendungen davon
US7435390B2 (en) * 2001-01-26 2008-10-14 Third Wave Technologies, Inc. Nucleic acid synthesizers
US6932943B1 (en) 2001-01-26 2005-08-23 Third Wave Technologies Nucleic acid synthesizers
EP1412522A1 (en) 2001-06-15 2004-04-28 Quiatech AB Amplifiable probe
US7345163B2 (en) * 2002-08-28 2008-03-18 Quiatech Ab Process for separating and deprotecting oligonucleotides
EP1756307A1 (en) * 2004-05-20 2007-02-28 Trillion Genomics Limited Use of mass labelled probes to detect target nucleic acids using mass spectrometry
US20060068424A1 (en) * 2004-08-13 2006-03-30 Fuji Photo Film Co., Ltd. Biosensor
EP1788875A4 (en) * 2004-08-20 2010-12-15 Dharmacon Inc NEW LABELING CHEMISTRY OF POLYNUCLEOTIDE SYNTHESIS
CA2848304A1 (en) 2011-09-09 2013-03-14 The Board Of Trustees Of The Leland Stanford Junior University Methods for sequencing a polynucleotide
US10378051B2 (en) * 2011-09-29 2019-08-13 Illumina Cambridge Limited Continuous extension and deblocking in reactions for nucleic acids synthesis and sequencing
JP2013198425A (ja) * 2012-03-24 2013-10-03 Kanagawa Univ オリゴヌクレオチドの製造方法
US10533216B2 (en) 2014-05-23 2020-01-14 Centrillion Technology Holdings Corporation Oligonucleotide probe inversion process for in situ synthesized probe arrays
US10695735B2 (en) 2015-08-18 2020-06-30 Centrillion Technology Holdings Corporation Probe inversion process for in situ synthesized probe arrays
CN106467913B (zh) * 2015-08-18 2021-07-20 生捷科技控股公司 用于原位合成探针阵列的探针倒转方法
WO2018102660A1 (en) * 2016-12-02 2018-06-07 Centrillion Technologies, Inc. In situ probe inversion process for constructing probe arrays
CN112204176A (zh) * 2018-03-21 2021-01-08 生捷科技控股公司 用于制造dna测序阵列的方法和系统

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE113059T1 (de) * 1987-06-24 1994-11-15 Florey Howard Inst Nukleosid-derivate.
SE9003743D0 (sv) 1990-11-26 1990-11-26 Pharmacia Ab Method and means for oligonucleotide synthesis
US5550215A (en) 1991-11-22 1996-08-27 Holmes; Christopher P. Polymer reversal on solid surfaces
US5462854A (en) * 1993-04-19 1995-10-31 Beckman Instruments, Inc. Inverse linkage oligonucleotides for chemical and enzymatic processes
SE9701783D0 (sv) * 1997-05-14 1997-05-14 Marek Kwiatkowski In situ synthesis of oligonucleotides of inverse orientation

Also Published As

Publication number Publication date
JP2001525821A (ja) 2001-12-11
ATE332911T1 (de) 2006-08-15
CA2289204A1 (en) 1998-11-19
US6313284B1 (en) 2001-11-06
WO1998051698A8 (en) 1999-06-10
US6790946B2 (en) 2004-09-14
WO1998051698A1 (en) 1998-11-19
DE69835207D1 (de) 2006-08-24
US20020051994A1 (en) 2002-05-02
EP0983288A1 (en) 2000-03-08
EP0983288B1 (en) 2006-07-12

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