CA2389232C - Associating hydrogels for nucleus pulposus replacement in intervertebral discs - Google Patents

Associating hydrogels for nucleus pulposus replacement in intervertebral discs Download PDF

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Publication number
CA2389232C
CA2389232C CA002389232A CA2389232A CA2389232C CA 2389232 C CA2389232 C CA 2389232C CA 002389232 A CA002389232 A CA 002389232A CA 2389232 A CA2389232 A CA 2389232A CA 2389232 C CA2389232 C CA 2389232C
Authority
CA
Canada
Prior art keywords
pva
nucleus
replacement
hydrogels
prosthetic nucleus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002389232A
Other languages
English (en)
French (fr)
Other versions
CA2389232A1 (en
Inventor
Michele Staud Marcolongo
Anthony Michael Lowman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Drexel University
Original Assignee
Drexel University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drexel University filed Critical Drexel University
Publication of CA2389232A1 publication Critical patent/CA2389232A1/en
Application granted granted Critical
Publication of CA2389232C publication Critical patent/CA2389232C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/441—Joints for the spine, e.g. vertebrae, spinal discs made of inflatable pockets or chambers filled with fluid, e.g. with hydrogel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Paper (AREA)
CA002389232A 1999-10-29 2000-10-27 Associating hydrogels for nucleus pulposus replacement in intervertebral discs Expired - Fee Related CA2389232C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16233899P 1999-10-29 1999-10-29
US60/162,338 1999-10-29
PCT/US2000/029874 WO2001032100A2 (en) 1999-10-29 2000-10-27 Associating hydrogels for nucleus pulposus replacement in intervertebral discs

Publications (2)

Publication Number Publication Date
CA2389232A1 CA2389232A1 (en) 2001-05-10
CA2389232C true CA2389232C (en) 2008-07-29

Family

ID=22585202

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002389232A Expired - Fee Related CA2389232C (en) 1999-10-29 2000-10-27 Associating hydrogels for nucleus pulposus replacement in intervertebral discs

Country Status (11)

Country Link
US (1) US20070106387A1 (https=)
EP (1) EP1229873B1 (https=)
JP (1) JP4833475B2 (https=)
AT (1) ATE257397T1 (https=)
AU (1) AU782208B2 (https=)
CA (1) CA2389232C (https=)
DE (1) DE60007656T2 (https=)
DK (1) DK1229873T3 (https=)
ES (1) ES2213628T3 (https=)
PT (1) PT1229873E (https=)
WO (1) WO2001032100A2 (https=)

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MXPA03000060A (es) 2000-06-30 2004-09-13 Synthes Ag Dispositivo para inyectar cemento de hueso.
MY133943A (en) 2000-08-22 2007-11-30 Synthes Gmbh Bone replacement material
TW200400062A (en) 2002-04-03 2004-01-01 Mathys Medizinaltechnik Ag Kneadable, pliable bone replacement material
US7001433B2 (en) 2002-05-23 2006-02-21 Pioneer Laboratories, Inc. Artificial intervertebral disc device
US8388684B2 (en) 2002-05-23 2013-03-05 Pioneer Signal Technology, Inc. Artificial disc device
US7485670B2 (en) 2002-08-02 2009-02-03 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
US7745532B2 (en) 2002-08-02 2010-06-29 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
US6951562B2 (en) 2002-11-13 2005-10-04 Ralph Fritz Zwirnmann Adjustable length tap and method for drilling and tapping a bore in bone
JP2006518256A (ja) * 2003-01-31 2006-08-10 ジンマー オーソバイオロジクス，インコーポレイティド 髄核組織（ｎｕｃｌｅｕｓｐｕｌｐｏｓｕｓｔｉｓｓｕｅ）を含むヒドロゲル組成物
EP2060280A3 (en) 2003-04-30 2009-05-27 Drexel University Thermogelling polymer blends for biomaterial applications
JP4607762B2 (ja) 2003-08-08 2011-01-05 ジンテーズ ゲゼルシャフト ミト ベシュレンクテル ハフツング 多孔性骨代替材料を含浸する方法
EP1663333B1 (en) 2003-09-05 2018-11-07 Synthes GmbH Bone cement compositions having fiber-reinforcement and/or increased flowability
WO2005034781A1 (en) 2003-09-29 2005-04-21 Promethean Surgical Devices Llc Devices and methods for spine repair
US9445916B2 (en) 2003-10-22 2016-09-20 Pioneer Surgical Technology, Inc. Joint arthroplasty devices having articulating members
US7910124B2 (en) 2004-02-06 2011-03-22 Georgia Tech Research Corporation Load bearing biocompatible device
US8002830B2 (en) * 2004-02-06 2011-08-23 Georgia Tech Research Corporation Surface directed cellular attachment
US8029511B2 (en) 2004-03-22 2011-10-04 Disc Dynamics, Inc. Multi-stage biomaterial injection system for spinal implants
US8211351B2 (en) 2004-05-13 2012-07-03 Synthes Usa, Llc Resorbable polymeric medical goods with improved mechanical properties and method for producing same
US20060100304A1 (en) 2004-05-21 2006-05-11 Synthes Inc. Replacement or supplementation of a nucleus pulposus using a hydrogel
JP4414461B2 (ja) 2004-06-03 2010-02-10 ジンテーズ ゲゼルシャフト ミト ベシュレンクテル ハフツング 多孔性骨代用材料の含浸のための装置
US8012501B2 (en) 2004-06-10 2011-09-06 Synthes Usa, Llc Flexible bone composite
US8460378B2 (en) 2004-07-26 2013-06-11 DePuy Sythes Products, LLC Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio
EP1778134A1 (en) * 2004-07-27 2007-05-02 Synthes USA Supplementation or replacement of a nucleus pulposus, of an intervertebral disc
WO2006099751A1 (en) 2005-03-24 2006-09-28 Synthes Gmbh Device for the cement augmentation of bone implants
US7914810B2 (en) 2005-05-06 2011-03-29 Synthes Usa, Llc Methods for the in situ treatment of bone cancer
JP4857437B2 (ja) * 2005-06-13 2012-01-18 日本メディカルマテリアル株式会社 髄核用脊椎椎間板置換材料およびその製造方法
DE602006013649D1 (en) * 2005-08-26 2010-05-27 Synthes Gmbh Hydrogel-ballonprothese für nucleus pulposus
CN103251449B (zh) 2005-10-13 2016-03-02 斯恩蒂斯有限公司 载药包装物
WO2007048016A2 (en) 2005-10-20 2007-04-26 Synthes (U.S.A.) Perfusion device and method
GB0523999D0 (en) * 2005-11-25 2006-01-04 Univ Manchester Microgel particle
US8715350B2 (en) 2006-09-15 2014-05-06 Pioneer Surgical Technology, Inc. Systems and methods for securing an implant in intervertebral space
US8197491B2 (en) 2006-12-19 2012-06-12 Synthes Usa, Llc Injectable fastener system and method
EP2757964B1 (en) 2011-05-26 2016-05-04 Cartiva, Inc. Tapered joint implant and related tools
US9198769B2 (en) 2011-12-23 2015-12-01 Pioneer Surgical Technology, Inc. Bone anchor assembly, bone plate system, and method
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
WO2014105972A1 (en) 2012-12-26 2014-07-03 Koss Scott A Apparatus, kit, and method for percutaneous intervertebral disc restoration
CN105555328B (zh) 2013-06-21 2019-01-11 德普伊新特斯产品公司 膜及制造方法
EP3277228B1 (en) 2015-03-31 2020-01-15 Cartiva, Inc. Carpometacarpal (cmc) implants
WO2016161025A1 (en) 2015-03-31 2016-10-06 Cartiva, Inc. Hydrogel implants with porous materials and methods
WO2016168363A1 (en) 2015-04-14 2016-10-20 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
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JPH0286838A (ja) * 1988-09-22 1990-03-27 Terumo Corp 水不溶性ヒドロゲルおよびその製造方法
US5143071A (en) * 1989-03-30 1992-09-01 Nepera, Inc. Non-stringy adhesive hydrophilic gels
US5192326A (en) * 1990-12-21 1993-03-09 Pfizer Hospital Products Group, Inc. Hydrogel bead intervertebral disc nucleus
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US5262475A (en) * 1992-05-12 1993-11-16 Film Specialties, Inc. Hydrophilic compositions which are fog-resistant
US5534028A (en) * 1993-04-20 1996-07-09 Howmedica, Inc. Hydrogel intervertebral disc nucleus with diminished lateral bulging
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US5846214A (en) * 1996-03-29 1998-12-08 Nichiban Company Limited PVA hydrogel, hydrogel laminate using the same and hydrogel wound-dressing material using the same
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US5981826A (en) * 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
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Also Published As

Publication number Publication date
DK1229873T3 (da) 2004-05-17
PT1229873E (pt) 2004-03-31
US20070106387A1 (en) 2007-05-10
EP1229873A2 (en) 2002-08-14
JP2003513685A (ja) 2003-04-15
WO2001032100A3 (en) 2001-11-22
AU1444401A (en) 2001-05-14
EP1229873B1 (en) 2004-01-07
WO2001032100A2 (en) 2001-05-10
JP4833475B2 (ja) 2011-12-07
DE60007656T2 (de) 2004-06-24
AU782208B2 (en) 2005-07-14
ATE257397T1 (de) 2004-01-15
ES2213628T3 (es) 2004-09-01
DE60007656D1 (de) 2004-02-12
CA2389232A1 (en) 2001-05-10
EP1229873A4 (en) 2003-01-15

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Effective date: 20191028