CA2386029A1 - P-glycoproteins from macaca fascicularis and uses thereof - Google Patents

P-glycoproteins from macaca fascicularis and uses thereof Download PDF

Info

Publication number
CA2386029A1
CA2386029A1 CA002386029A CA2386029A CA2386029A1 CA 2386029 A1 CA2386029 A1 CA 2386029A1 CA 002386029 A CA002386029 A CA 002386029A CA 2386029 A CA2386029 A CA 2386029A CA 2386029 A1 CA2386029 A1 CA 2386029A1
Authority
CA
Canada
Prior art keywords
glycoprotein
cynomologous
pgp
leu
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002386029A
Other languages
English (en)
French (fr)
Inventor
Penny J. Stocker
Dorothy T. Steimel-Crespi
Charles L. Crespi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gentest Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2386029A1 publication Critical patent/CA2386029A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002386029A 1999-09-28 2000-09-28 P-glycoproteins from macaca fascicularis and uses thereof Abandoned CA2386029A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15692199P 1999-09-28 1999-09-28
US60/156,921 1999-09-28
US15881899P 1999-10-12 1999-10-12
US60/158,818 1999-10-12
PCT/US2000/026592 WO2001023565A1 (en) 1999-09-28 2000-09-28 P-glycoproteins from macaca fascicularis and uses thereof

Publications (1)

Publication Number Publication Date
CA2386029A1 true CA2386029A1 (en) 2001-04-05

Family

ID=26853651

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002386029A Abandoned CA2386029A1 (en) 1999-09-28 2000-09-28 P-glycoproteins from macaca fascicularis and uses thereof

Country Status (6)

Country Link
US (2) US6617450B1 (enExample)
EP (1) EP1220917A1 (enExample)
JP (2) JP2003510078A (enExample)
AU (1) AU7835600A (enExample)
CA (1) CA2386029A1 (enExample)
WO (1) WO2001023565A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6855812B2 (en) 2001-03-19 2005-02-15 Becton, Dickinson And Company P-glycoproteins and uses thereof
US20050153914A1 (en) * 2001-05-18 2005-07-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of MDR P-glycoprotein gene expression using short interfering nucleic acid (siNA)
CA2820537C (en) 2003-04-23 2015-10-20 Valeritas, Inc. Hydraulically actuated pump for fluid administration
US20060084799A1 (en) * 2003-09-24 2006-04-20 Williams Lewis T Human cDNA clones comprising polynucleotides encoding polypeptides and methods of their use
CA2549295C (en) 2003-12-04 2016-05-03 University Of Utah Research Foundation Modified macromolecules and methods of making and using thereof
US20100330143A1 (en) 2003-12-04 2010-12-30 University Of Utah Research Foundation Modified macromolecules and methods of making and using thereof
US9089636B2 (en) 2004-07-02 2015-07-28 Valeritas, Inc. Methods and devices for delivering GLP-1 and uses thereof
ES2656675T3 (es) 2006-03-30 2018-02-28 Valeritas, Inc. Dispositivo de suministro de fluidos de múltiples cartuchos
EP2041312B1 (en) * 2006-07-14 2010-12-01 The Govt. of the USA as Represented by the Secretary of the Dept. of Health and Human Services Abcbi genotyping to predict microtubule-stabilizing-agent-induced toxicity
JP2013545440A (ja) * 2010-09-27 2013-12-26 ヤンセン バイオテツク,インコーポレーテツド マカカ・ファシキュラリス(Macacafascicularis)CCL17
WO2013010045A1 (en) 2011-07-12 2013-01-17 Biotime Inc. Novel methods and formulations for orthopedic cell therapy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE122727T1 (de) * 1986-03-28 1995-06-15 Univ Illinois Zubereitungen und verfahren für klone, die, mit mehrfacharzneimittelresistenz assoziierte, dna- sequenzen in menschlichen zellen enthalten.
US5429921A (en) 1988-04-04 1995-07-04 The Salk Institute Biotechnology/Industrial Assoc. Inc. Assays for agonists and antagonists of recombinant human calcium channels
CA2113578A1 (en) * 1991-07-19 1993-02-04 Ann E. Huang Trifunctional compounds having specificity for multi-drug resistant cells
WO1993024613A1 (en) * 1992-05-22 1993-12-09 The United States Government As Represented By The Secretary Of The Department Of Health And Human Services Improved expression of human multidrug resistance genes and improved selection of cells transduced with such genes
WO1998013072A1 (en) * 1996-09-24 1998-04-02 Thomas Jefferson University Compositions for and methods of treating multiple drug resistance
AU4214799A (en) * 1998-05-28 1999-12-13 St. Jude Children's Research Hospital Expansion of hematopoietic stem cells transduced with mdr-1 and methods of use thereof
WO2000018886A1 (en) * 1998-09-25 2000-04-06 Wisconsin Alumni Research Foundation Xenobiotic detoxification gene from plants

Also Published As

Publication number Publication date
US6617450B1 (en) 2003-09-09
WO2001023565A1 (en) 2001-04-05
JP2003510078A (ja) 2003-03-18
AU7835600A (en) 2001-04-30
EP1220917A1 (en) 2002-07-10
JP2012065671A (ja) 2012-04-05
US20040077000A1 (en) 2004-04-22

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued