CA2385851A1 - Three-dimensional microarray system for parallel genotyping of single nucleotide polymorphisms - Google Patents
Three-dimensional microarray system for parallel genotyping of single nucleotide polymorphisms Download PDFInfo
- Publication number
- CA2385851A1 CA2385851A1 CA002385851A CA2385851A CA2385851A1 CA 2385851 A1 CA2385851 A1 CA 2385851A1 CA 002385851 A CA002385851 A CA 002385851A CA 2385851 A CA2385851 A CA 2385851A CA 2385851 A1 CA2385851 A1 CA 2385851A1
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Classifications
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
- B01J2219/00644—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being present in discrete locations, e.g. gel pads
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00664—Three-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
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- Immunology (AREA)
- Biochemistry (AREA)
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- Physics & Mathematics (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15543199P | 1999-09-22 | 1999-09-22 | |
| US60/155,431 | 1999-09-22 | ||
| PCT/US2000/025988 WO2001021838A2 (en) | 1999-09-22 | 2000-09-22 | Three-dimensional microarray system for parallel genotyping of single nucleotide polymorphisms |
Publications (1)
| Publication Number | Publication Date |
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| CA2385851A1 true CA2385851A1 (en) | 2001-03-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CA002385851A Abandoned CA2385851A1 (en) | 1999-09-22 | 2000-09-22 | Three-dimensional microarray system for parallel genotyping of single nucleotide polymorphisms |
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|---|---|
| EP (1) | EP1222310A2 (https=) |
| JP (1) | JP2003510054A (https=) |
| AU (1) | AU7708500A (https=) |
| CA (1) | CA2385851A1 (https=) |
| WO (1) | WO2001021838A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2002353997A1 (en) | 2001-11-01 | 2003-05-12 | Rensselaer Polytechnic Institute | In vitro metabolic engineering on microscale devices |
| US11001881B2 (en) | 2006-08-24 | 2021-05-11 | California Institute Of Technology | Methods for detecting analytes |
| US8048626B2 (en) | 2006-07-28 | 2011-11-01 | California Institute Of Technology | Multiplex Q-PCR arrays |
| US11525156B2 (en) | 2006-07-28 | 2022-12-13 | California Institute Of Technology | Multiplex Q-PCR arrays |
| US11560588B2 (en) | 2006-08-24 | 2023-01-24 | California Institute Of Technology | Multiplex Q-PCR arrays |
| US20120141986A1 (en) * | 2007-03-27 | 2012-06-07 | Kenneth Kuhn | Multivalent substrate elements for detection of nucleic acid sequences |
| US9708647B2 (en) | 2015-03-23 | 2017-07-18 | Insilixa, Inc. | Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays |
| US9499861B1 (en) | 2015-09-10 | 2016-11-22 | Insilixa, Inc. | Methods and systems for multiplex quantitative nucleic acid amplification |
| WO2017155858A1 (en) | 2016-03-07 | 2017-09-14 | Insilixa, Inc. | Nucleic acid sequence identification using solid-phase cyclic single base extension |
| CN110678557A (zh) | 2017-03-31 | 2020-01-10 | 玛赛拉·基亚里 | 通过管内杂交与通用标签-微阵列的组合的突变的基因分型 |
| JP7687957B2 (ja) | 2019-03-14 | 2025-06-03 | インシリクサ， インコーポレイテッド | 時間ゲート蛍光ベースの検出のための方法およびシステム |
| CN116023412A (zh) * | 2021-10-25 | 2023-04-28 | 中元汇吉生物技术股份有限公司 | 一种修饰的核苷酸、组合物及试剂 |
| CN113943324B (zh) * | 2021-10-25 | 2023-07-28 | 中元汇吉生物技术股份有限公司 | 一种修饰的核苷酸，组合物及试剂 |
Family Cites Families (8)
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| IE66572B1 (en) * | 1989-02-13 | 1996-01-24 | Geneco Pty Ltd | Detection of a nucleic acid sequence or a change therein |
| RU1794088C (ru) * | 1991-03-18 | 1993-02-07 | Институт Молекулярной Биологии Ан@ Ссср | Способ определени нуклеотидной последовательности ДНК и устройство дл его осуществлени |
| CA2115342C (en) * | 1992-06-17 | 2003-08-26 | Robert B. Wallace | A method of detecting and discriminating between nucleic acid sequences |
| RU2041261C1 (ru) * | 1993-08-11 | 1995-08-09 | Институт молекулярной биологии им.В.А.Энгельгардта РАН | Способ изготовления матрицы для детектирования мисматчей |
| AUPO427996A0 (en) * | 1996-12-20 | 1997-01-23 | Co-Operative Research Centre For Diagnostic Technologies | Method for detecting a nucleotide at a specific location within a polynucleotide sequence and apparatus therefor |
| JP2001517948A (ja) * | 1997-04-01 | 2001-10-09 | グラクソ、グループ、リミテッド | 核酸配列決定法 |
| US6048692A (en) * | 1997-10-07 | 2000-04-11 | Motorola, Inc. | Sensors for electrically sensing binding events for supported molecular receptors |
| US6391937B1 (en) * | 1998-11-25 | 2002-05-21 | Motorola, Inc. | Polyacrylamide hydrogels and hydrogel arrays made from polyacrylamide reactive prepolymers |
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2000
- 2000-09-22 JP JP2001525396A patent/JP2003510054A/ja active Pending
- 2000-09-22 EP EP00966797A patent/EP1222310A2/en not_active Withdrawn
- 2000-09-22 CA CA002385851A patent/CA2385851A1/en not_active Abandoned
- 2000-09-22 AU AU77085/00A patent/AU7708500A/en not_active Abandoned
- 2000-09-22 WO PCT/US2000/025988 patent/WO2001021838A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU7708500A (en) | 2001-04-24 |
| WO2001021838A2 (en) | 2001-03-29 |
| EP1222310A2 (en) | 2002-07-17 |
| WO2001021838A3 (en) | 2001-10-25 |
| JP2003510054A (ja) | 2003-03-18 |
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