CA2385551A1 - Metal-binding compounds and uses therefor - Google Patents
Metal-binding compounds and uses therefor Download PDFInfo
- Publication number
- CA2385551A1 CA2385551A1 CA002385551A CA2385551A CA2385551A1 CA 2385551 A1 CA2385551 A1 CA 2385551A1 CA 002385551 A CA002385551 A CA 002385551A CA 2385551 A CA2385551 A CA 2385551A CA 2385551 A1 CA2385551 A1 CA 2385551A1
- Authority
- CA
- Canada
- Prior art keywords
- peptide
- alanine
- xaa2
- amino acids
- hydroxymethylserine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 125000001624 naphthyl group Chemical group 0.000 description 1
- 210000004498 neuroglial cell Anatomy 0.000 description 1
- 230000003961 neuronal insult Effects 0.000 description 1
- 230000000324 neuroprotective effect Effects 0.000 description 1
- 229910001453 nickel ion Inorganic materials 0.000 description 1
- 239000012044 organic layer Substances 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000003950 pathogenic mechanism Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 229940097156 peroxyl Drugs 0.000 description 1
- 150000005041 phenanthrolines Chemical class 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- FAIAAWCVCHQXDN-UHFFFAOYSA-N phosphorus trichloride Chemical compound ClP(Cl)Cl FAIAAWCVCHQXDN-UHFFFAOYSA-N 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000002952 polymeric resin Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 150000004033 porphyrin derivatives Chemical class 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000017854 proteolysis Effects 0.000 description 1
- KIDHWZJUCRJVML-UHFFFAOYSA-N putrescine Chemical compound NCCCCN KIDHWZJUCRJVML-UHFFFAOYSA-N 0.000 description 1
- 150000003215 pyranoses Chemical class 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
- 239000012279 sodium borohydride Substances 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
- 150000003624 transition metals Chemical class 0.000 description 1
- 150000004043 trisaccharides Chemical class 0.000 description 1
- 229910052720 vanadium Inorganic materials 0.000 description 1
- GPPXJZIENCGNKB-UHFFFAOYSA-N vanadium Chemical compound [V]#[V] GPPXJZIENCGNKB-UHFFFAOYSA-N 0.000 description 1
- 229910001456 vanadium ion Inorganic materials 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15740499P | 1999-10-01 | 1999-10-01 | |
| US60/157,404 | 1999-10-01 | ||
| US21107800P | 2000-06-13 | 2000-06-13 | |
| US60/211,078 | 2000-06-13 | ||
| PCT/US2000/026952 WO2001025265A1 (en) | 1999-10-01 | 2000-09-29 | Metal-binding compounds and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2385551A1 true CA2385551A1 (en) | 2001-04-12 |
Family
ID=26854102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002385551A Abandoned CA2385551A1 (en) | 1999-10-01 | 2000-09-29 | Metal-binding compounds and uses therefor |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP2327713A1 (enExample) |
| JP (1) | JP5349722B2 (enExample) |
| KR (6) | KR20100075503A (enExample) |
| CN (2) | CN102038932B (enExample) |
| AT (1) | ATE553116T1 (enExample) |
| AU (1) | AU770999C (enExample) |
| BR (1) | BR0014389A (enExample) |
| CA (1) | CA2385551A1 (enExample) |
| IL (4) | IL148797A0 (enExample) |
| NZ (1) | NZ518266A (enExample) |
| WO (1) | WO2001025265A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030040602A1 (en) * | 2001-04-30 | 2003-02-27 | George Jackowski | Biopolymer marker indicative of disease state having a molecular weight of 1406 daltons |
| US20020160417A1 (en) * | 2001-04-30 | 2002-10-31 | George Jackowski | Biopolymer marker indicative of disease state having a molecular weight of 1424 daltons |
| AU2002348301B2 (en) * | 2001-11-20 | 2008-05-08 | Dmi Biosciences, Inc. | Methods and products for oral care |
| BR0315942A (pt) | 2002-11-27 | 2005-10-04 | Dmi Biosciences Inc | Tratamento de doenças e condições mediadas pelo aumento de fosforilação |
| CA2727803C (en) | 2008-05-13 | 2013-03-12 | University Of Kansas | Metal abstraction peptide (map) tag and associated methods |
| WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
| CN111925411B (zh) * | 2017-06-29 | 2022-04-08 | 安徽省农业科学院农产品加工研究所 | 一种含有Cys-Ser的高锌螯合活性锌螯合肽及其应用 |
| CN113563418B (zh) * | 2021-06-22 | 2023-03-03 | 中国科学院化学研究所 | 一种原位响应ros的人工酶及其制备方法与应用 |
| CN114437175B (zh) * | 2022-01-29 | 2023-09-29 | 山东第一医科大学第三附属医院(山东省医学科学院附属医院) | 一种肽探针及其应用和包含该肽探针的试剂盒 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3941763A (en) | 1975-03-28 | 1976-03-02 | American Home Products Corporation | PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates |
| US4022888A (en) | 1975-09-09 | 1977-05-10 | Diagnostic Data, Inc. | Esterified orgotein |
| US4461724A (en) | 1981-10-28 | 1984-07-24 | Nippon Zoki Pharmaceutical Co., Ltd. | Peptide compounds, a process for manufacturing them, pharmaceutical compositions containing them, and methods for treating ulcer and thrombus with them |
| US4912118A (en) | 1983-09-23 | 1990-03-27 | National Research Development Corporation | Pharmaceutical compositions |
| US4760051A (en) | 1985-01-24 | 1988-07-26 | Pickart Loren R | Use of GHL-Cu as a wound-healing and anti-inflammatory agent |
| US4877770A (en) | 1985-02-08 | 1989-10-31 | Procyte Corporation | Chemical derivatives of GHL-Cu |
| US4665054A (en) | 1985-02-08 | 1987-05-12 | Bioheal, Inc. | Chemical derivatives of GHL-Cu |
| US4767753A (en) | 1985-02-08 | 1988-08-30 | Procyte Corporation | Methods and compositions for preventing ulcers |
| US5550183A (en) | 1985-02-08 | 1996-08-27 | Procyte Corporation | Metal-peptide compositions and methods for stimulating hair growth |
| US5120831A (en) | 1985-02-08 | 1992-06-09 | Procyte Corporation | Metal-peptide compositions |
| US4810693A (en) | 1985-02-08 | 1989-03-07 | Procyte Corporation | Method for inducing biological coverings in wounds |
| US5177061A (en) | 1985-02-08 | 1993-01-05 | Procyte Corporation | Method for stimulating hair growth using GHL-Cu complexes |
| US5348943A (en) | 1985-02-08 | 1994-09-20 | Procyte Corporation | Cosmetic and skin treatment compositions |
| US5214032A (en) | 1985-02-08 | 1993-05-25 | Procyte Corporation | GHL-CU pharmaceutical compositions and compounds |
| US5422096A (en) | 1985-05-08 | 1995-06-06 | The General Hospital Corporation | Hydroxy-aryl metal chelates for diagnostic NMR imaging |
| JPS62116565A (ja) * | 1985-11-15 | 1987-05-28 | Fujisawa Pharmaceut Co Ltd | 新規ペプチド |
| GB8603537D0 (en) | 1986-02-13 | 1986-03-19 | Parker D | Conjugate compound |
| EP0314755B1 (en) | 1987-05-11 | 1994-08-24 | Procyte Corporation | Use of derivatives of GHL-Cu for the manufacture of a medicament for stimulating hair growth |
| ATE110954T1 (de) | 1988-01-29 | 1994-09-15 | Peter H Proctor | Haarwachstumanregung mit nitroxyd und anderen radikalen. |
| US5101041A (en) | 1989-04-26 | 1992-03-31 | The Curators Of The University Of Missouri | Triamines and their derivatives as bifunctional chelating agents |
| US5443816A (en) | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
| ATE172879T1 (de) | 1989-08-09 | 1998-11-15 | Rhomed Inc | Direkte radioetikettierung von antikörpern und sonstigen proteinen mittels technetium oder rhenium |
| US5460785A (en) | 1989-08-09 | 1995-10-24 | Rhomed Incorporated | Direct labeling of antibodies and other protein with metal ions |
| US5759515A (en) | 1989-08-09 | 1998-06-02 | Rhomed Incorporated | Polyvalent peptide pharmaceutical applications |
| US5023237A (en) | 1989-08-30 | 1991-06-11 | Procyte Corporation | Methods and compositions for healing ulcers |
| US5145838A (en) | 1989-08-30 | 1992-09-08 | Procyte Corporation | Methods and compositions for healing ulcers |
| US5059588A (en) | 1989-10-13 | 1991-10-22 | Procyte Corporation, Incorporated | Methods and compositions for healing bone using gly his lys: copper |
| US5118665A (en) | 1990-02-09 | 1992-06-02 | Procyte Corporation | Anti-oxidative and anti-inflammatory metal:peptide complexes and uses thereof |
| US5164367A (en) | 1990-03-26 | 1992-11-17 | Procyte Corporation | Method of using copper(ii) containing compounds to accelerate wound healing |
| US5252559A (en) | 1991-08-20 | 1993-10-12 | The Procter & Gamble Company | His-Gly-Gly peptide and derivatives thereof for hair growth |
| US5280038A (en) | 1992-03-13 | 1994-01-18 | Virginia Commonwealth University | Histidine as a protective agent in cardiac surgery and myocardial ischemic syndrome |
| CA2094785A1 (en) | 1992-05-08 | 1993-11-09 | Jean Gariepy | Metal chelating peptide |
| US5807535A (en) | 1992-07-31 | 1998-09-15 | Australian Nuclear Science & Technology Organisation | Metal complexes of hydroxyaryl containing aminocarboxylic acid chelating agents |
| US5380747A (en) | 1992-10-30 | 1995-01-10 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
| US5650134A (en) | 1993-01-12 | 1997-07-22 | Novartis Ag (Formerly Sandoz Ltd.) | Peptides |
| US5464934A (en) | 1993-05-14 | 1995-11-07 | Mallinckrodt Medical, Inc. | Metal chelates as spacer compounds in biologically active peptides |
| US5994339A (en) | 1993-10-15 | 1999-11-30 | University Of Alabama At Birmingham Research Foundation | Oxidant scavengers |
| US5476939A (en) | 1993-12-30 | 1995-12-19 | Abbott Laboratories | Certain pyridyl and isoquinolyl carbinolamine derivatives |
| JPH07316192A (ja) | 1994-05-27 | 1995-12-05 | Hoechst Japan Ltd | Ｌ−リシル−グリシル−ｌ−ヒスチジンおよびこれを含有する創傷治療剤 |
| US5538945A (en) | 1994-06-17 | 1996-07-23 | Procyte Corporation | Stimulation of hair growth by peptide copper complexes |
| US5891418A (en) | 1995-06-07 | 1999-04-06 | Rhomed Incorporated | Peptide-metal ion pharmaceutical constructs and applications |
| EP0955044B1 (en) | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
| US5637311A (en) | 1995-06-29 | 1997-06-10 | Procyte Corporation | Zinc(II) complexes and methods related thereto |
| RU2106146C1 (ru) | 1995-07-17 | 1998-03-10 | Институт элементоорганических соединений РАН | Средство для подавления опухолевого роста |
| US5786335A (en) | 1995-11-06 | 1998-07-28 | Warner-Lambert Company | Sulfhydryl containing peptides for treating vascular disease |
| US5928955A (en) | 1996-03-22 | 1999-07-27 | California Institute Of Technology | Peptidyl fluorescent chemosensor for divalent zinc |
| WO1997044313A1 (en) | 1996-05-21 | 1997-11-27 | Novartis Ag | N,N'-Di(2-HYDROXYBENZYL)ETHYLENEDIAMINE-N,N'-DIACETIC ACID DERIVATIVES |
| GB9613182D0 (en) | 1996-06-24 | 1996-08-28 | Nycomed Imaging As | Method |
| PL184070B1 (pl) | 1996-07-30 | 2002-08-30 | Politechnika Lodzka | Sposób wytwarzania peptydów zawierających a-hydroksymetyloserynę |
| US5906996A (en) | 1996-08-21 | 1999-05-25 | Murphy; Michael A. | Tetramine treatment of neurological disorders |
| US5922761A (en) | 1996-09-06 | 1999-07-13 | Medinox, Inc. | Methods for in vivo reduction of iron levels and compositions useful therefor |
| US5739395A (en) | 1997-01-10 | 1998-04-14 | University Of Florida Research Foundation, Inc. | Method for synthesis of rhizoferrin |
| GB9711093D0 (en) | 1997-05-29 | 1997-07-23 | British Tech Group | Novel orally active iron (III) chelators |
| TR200002256T2 (tr) | 1998-02-04 | 2001-03-21 | University Of Florida Research Foundation, Inc. | Demir celatlama tedavisinde N,N' -BIS(2-Hidroksibenzil) etilendiamin-N, N'diasetik asit içeren farmasötikler. |
| DE19819843A1 (de) | 1998-05-05 | 1999-11-11 | Biotechnolog Forschung Gmbh | Metallchelat bindende Peptide |
| CA2328457A1 (en) | 1998-06-20 | 1999-12-29 | Washington University | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
-
2000
- 2000-09-29 AT AT00967163T patent/ATE553116T1/de active
- 2000-09-29 CN CN2010105807752A patent/CN102038932B/zh not_active Expired - Fee Related
- 2000-09-29 JP JP2001528205A patent/JP5349722B2/ja not_active Expired - Fee Related
- 2000-09-29 CA CA002385551A patent/CA2385551A1/en not_active Abandoned
- 2000-09-29 KR KR1020107008232A patent/KR20100075503A/ko not_active Ceased
- 2000-09-29 KR KR1020117031645A patent/KR101312880B1/ko not_active Expired - Fee Related
- 2000-09-29 NZ NZ518266A patent/NZ518266A/en not_active IP Right Cessation
- 2000-09-29 EP EP10183238A patent/EP2327713A1/en not_active Withdrawn
- 2000-09-29 KR KR1020117031646A patent/KR101353140B1/ko not_active Expired - Fee Related
- 2000-09-29 CN CN00815718A patent/CN1390231A/zh active Pending
- 2000-09-29 KR KR1020097012559A patent/KR101062041B1/ko not_active Expired - Fee Related
- 2000-09-29 AU AU77407/00A patent/AU770999C/en not_active Ceased
- 2000-09-29 EP EP00967163A patent/EP1220870B1/en not_active Expired - Lifetime
- 2000-09-29 WO PCT/US2000/026952 patent/WO2001025265A1/en not_active Ceased
- 2000-09-29 IL IL14879700A patent/IL148797A0/xx unknown
- 2000-09-29 KR KR1020027004228A patent/KR20020057966A/ko not_active Ceased
- 2000-09-29 KR KR1020117006608A patent/KR20110049875A/ko not_active Ceased
- 2000-09-29 BR BR0014389-8A patent/BR0014389A/pt not_active IP Right Cessation
-
2002
- 2002-03-20 IL IL148797A patent/IL148797A/en not_active IP Right Cessation
-
2009
- 2009-12-17 IL IL202812A patent/IL202812A0/en unknown
-
2010
- 2010-09-01 IL IL207923A patent/IL207923A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120023147A (ko) | 2012-03-12 |
| IL148797A (en) | 2010-12-30 |
| KR20090086437A (ko) | 2009-08-12 |
| ATE553116T1 (de) | 2012-04-15 |
| KR20100075503A (ko) | 2010-07-02 |
| EP1220870B1 (en) | 2012-04-11 |
| IL207923A0 (en) | 2011-07-31 |
| KR20120024890A (ko) | 2012-03-14 |
| IL148797A0 (en) | 2002-09-12 |
| JP2003528814A (ja) | 2003-09-30 |
| NZ518266A (en) | 2005-01-28 |
| EP1220870A1 (en) | 2002-07-10 |
| CN102038932A (zh) | 2011-05-04 |
| KR101062041B1 (ko) | 2011-09-02 |
| KR101312880B1 (ko) | 2013-09-30 |
| CN102038932B (zh) | 2013-11-06 |
| AU7740700A (en) | 2001-05-10 |
| KR101353140B1 (ko) | 2014-01-20 |
| HK1157635A1 (en) | 2012-07-06 |
| AU770999B2 (en) | 2004-03-11 |
| IL202812A0 (en) | 2011-07-31 |
| EP1220870A4 (en) | 2004-04-07 |
| CN1390231A (zh) | 2003-01-08 |
| WO2001025265A1 (en) | 2001-04-12 |
| KR20110049875A (ko) | 2011-05-12 |
| KR20020057966A (ko) | 2002-07-12 |
| EP2327713A1 (en) | 2011-06-01 |
| JP5349722B2 (ja) | 2013-11-20 |
| BR0014389A (pt) | 2002-10-29 |
| AU770999C (en) | 2005-04-21 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20150929 |