CA2380653A1 - Mycophenolate mofetil in association with peg-ifn-.alpha. - Google Patents
Mycophenolate mofetil in association with peg-ifn-.alpha. Download PDFInfo
- Publication number
- CA2380653A1 CA2380653A1 CA002380653A CA2380653A CA2380653A1 CA 2380653 A1 CA2380653 A1 CA 2380653A1 CA 002380653 A CA002380653 A CA 002380653A CA 2380653 A CA2380653 A CA 2380653A CA 2380653 A1 CA2380653 A1 CA 2380653A1
- Authority
- CA
- Canada
- Prior art keywords
- ifn
- alpha
- peg
- effective amount
- prodrug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- RTGDFNSFWBGLEC-SYZQJQIISA-N mycophenolate mofetil Chemical compound COC1=C(C)C=2COC(=O)C=2C(O)=C1C\C=C(/C)CCC(=O)OCCN1CCOCC1 RTGDFNSFWBGLEC-SYZQJQIISA-N 0.000 title description 10
- 229960004866 mycophenolate mofetil Drugs 0.000 title description 4
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical compound OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 claims abstract description 42
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 claims abstract description 40
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99115950.0 | 1999-08-13 | ||
| EP99115950 | 1999-08-13 | ||
| US18790700P | 2000-03-08 | 2000-03-08 | |
| US60/187,907 | 2000-03-08 | ||
| PCT/EP2000/007666 WO2001012214A2 (en) | 1999-08-13 | 2000-08-08 | MYCOPHENOLATE MOFETIL IN ASSOCIATION WITH PEG-IFN-$g(a) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2380653A1 true CA2380653A1 (en) | 2001-02-22 |
Family
ID=29762814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002380653A Abandoned CA2380653A1 (en) | 1999-08-13 | 2000-08-08 | Mycophenolate mofetil in association with peg-ifn-.alpha. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1220683A2 (pt) |
| JP (1) | JP2003507339A (pt) |
| CN (1) | CN1368887A (pt) |
| AU (1) | AU7408200A (pt) |
| BR (1) | BR0013252A (pt) |
| CA (1) | CA2380653A1 (pt) |
| HU (1) | HUP0202525A3 (pt) |
| MX (1) | MXPA02001296A (pt) |
| PE (1) | PE20010490A1 (pt) |
| PL (1) | PL357367A1 (pt) |
| RU (1) | RU2002105485A (pt) |
| TR (1) | TR200200401T2 (pt) |
| WO (1) | WO2001012214A2 (pt) |
| ZA (1) | ZA200200280B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0307553D0 (en) * | 2003-04-01 | 2003-05-07 | Novartis Ag | Organic compounds |
| EP1719773B1 (en) | 2004-02-24 | 2009-04-15 | Japan Tobacco, Inc. | Fused heterotetracyclic compounds and use tehreof as hcv polymerase inhibitor |
| US20070049593A1 (en) | 2004-02-24 | 2007-03-01 | Japan Tobacco Inc. | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor |
| WO2006020720A2 (en) * | 2004-08-12 | 2006-02-23 | Schering Corporation | Stable pegylated interferon formulation |
| US7659263B2 (en) | 2004-11-12 | 2010-02-09 | Japan Tobacco Inc. | Thienopyrrole compound and use thereof as HCV polymerase inhibitor |
| US8017612B2 (en) | 2006-04-18 | 2011-09-13 | Japan Tobacco Inc. | Piperazine compound and use thereof as a HCV polymerase inhibitor |
| WO2010110503A1 (ko) * | 2009-03-27 | 2010-09-30 | 주식회사 중외제약 | 인터페론-알파 및 세포질 잔류성 세포막 투과 펩타이드를 포함하는 IFN-α 융합 단백질 |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| BR112014005617A2 (pt) | 2011-10-21 | 2017-06-13 | Abbvie Inc | tratamento de combinação (por exemplo, com abt-072 ou abt -333) de daas para uso no tratamento de hcv |
| ES2572329B1 (es) | 2011-10-21 | 2017-08-24 | Abbvie Inc. | Combinación de al menos dos agentes antivirales de acción directa y ribavirina pero no interferón, para uso en el tratamientodel vhc |
| US11559567B2 (en) * | 2014-11-06 | 2023-01-24 | Pharmaessentia Corporation | Dosage regimen for pegylated interferon |
| WO2017189978A1 (en) | 2016-04-28 | 2017-11-02 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5908621A (en) * | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| MY125300A (en) * | 1999-02-26 | 2006-07-31 | Inst Of Molecular And Cell Biology | Synergistic combination for treatment of viral-mediated diseases |
-
2000
- 2000-08-08 BR BR0013252-7A patent/BR0013252A/pt not_active IP Right Cessation
- 2000-08-08 PE PE2000000804A patent/PE20010490A1/es not_active Application Discontinuation
- 2000-08-08 AU AU74082/00A patent/AU7408200A/en not_active Abandoned
- 2000-08-08 EP EP00962297A patent/EP1220683A2/en not_active Withdrawn
- 2000-08-08 CN CN00811397A patent/CN1368887A/zh active Pending
- 2000-08-08 WO PCT/EP2000/007666 patent/WO2001012214A2/en not_active Application Discontinuation
- 2000-08-08 PL PL00357367A patent/PL357367A1/xx not_active Application Discontinuation
- 2000-08-08 RU RU2002105485/15A patent/RU2002105485A/ru not_active Application Discontinuation
- 2000-08-08 CA CA002380653A patent/CA2380653A1/en not_active Abandoned
- 2000-08-08 JP JP2001516559A patent/JP2003507339A/ja active Pending
- 2000-08-08 HU HU0202525A patent/HUP0202525A3/hu unknown
- 2000-08-08 MX MXPA02001296A patent/MXPA02001296A/es unknown
- 2000-08-08 TR TR2002/00401T patent/TR200200401T2/xx unknown
-
2002
- 2002-01-11 ZA ZA200200280A patent/ZA200200280B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR200200401T2 (tr) | 2002-06-21 |
| JP2003507339A (ja) | 2003-02-25 |
| AU7408200A (en) | 2001-03-13 |
| HUP0202525A2 (hu) | 2002-11-28 |
| WO2001012214A3 (en) | 2001-10-04 |
| CN1368887A (zh) | 2002-09-11 |
| HUP0202525A3 (en) | 2003-11-28 |
| MXPA02001296A (es) | 2002-07-22 |
| RU2002105485A (ru) | 2004-01-27 |
| PL357367A1 (en) | 2004-07-26 |
| WO2001012214A2 (en) | 2001-02-22 |
| BR0013252A (pt) | 2002-04-16 |
| EP1220683A2 (en) | 2002-07-10 |
| PE20010490A1 (es) | 2001-04-27 |
| ZA200200280B (en) | 2003-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |