CA2379327A1 - Pneumococcal surface protein combination vaccine - Google Patents

Pneumococcal surface protein combination vaccine Download PDF

Info

Publication number
CA2379327A1
CA2379327A1 CA002379327A CA2379327A CA2379327A1 CA 2379327 A1 CA2379327 A1 CA 2379327A1 CA 002379327 A CA002379327 A CA 002379327A CA 2379327 A CA2379327 A CA 2379327A CA 2379327 A1 CA2379327 A1 CA 2379327A1
Authority
CA
Canada
Prior art keywords
epitope
pspa
psaa
pspc
pneumococcal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002379327A
Other languages
English (en)
French (fr)
Inventor
George M. Carlone
Edwin Ades
Robert C. Huebner
Jacquelyn S. Sampson
David E. Briles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
UAB Research Foundation
Centers of Disease Control and Prevention CDC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2379327A1 publication Critical patent/CA2379327A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002379327A 1999-06-10 2000-06-09 Pneumococcal surface protein combination vaccine Abandoned CA2379327A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13842299P 1999-06-10 1999-06-10
US60/138,422 1999-06-10
US58783300A 2000-06-06 2000-06-06
US09/587,833 2000-06-06
PCT/US2000/040176 WO2000076541A1 (en) 1999-06-10 2000-06-09 Pneumococcal surface protein combination vaccine

Publications (1)

Publication Number Publication Date
CA2379327A1 true CA2379327A1 (en) 2000-12-21

Family

ID=26836182

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002379327A Abandoned CA2379327A1 (en) 1999-06-10 2000-06-09 Pneumococcal surface protein combination vaccine

Country Status (7)

Country Link
EP (1) EP1189632A4 (cg-RX-API-DMAC7.html)
JP (1) JP2003519089A (cg-RX-API-DMAC7.html)
AU (1) AU6121000A (cg-RX-API-DMAC7.html)
BR (1) BR0011478A (cg-RX-API-DMAC7.html)
CA (1) CA2379327A1 (cg-RX-API-DMAC7.html)
MX (1) MXPA01012721A (cg-RX-API-DMAC7.html)
WO (1) WO2000076541A1 (cg-RX-API-DMAC7.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US20010016200A1 (en) 1998-04-23 2001-08-23 Briles David E. Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
GB0022742D0 (en) * 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
EP1477802A1 (en) * 2003-05-16 2004-11-17 Erasmus Universiteit Rotterdam Method for selecting and producing vaccine components and vaccines based thereon
JP2010501012A (ja) * 2006-08-17 2010-01-14 ザ ユーエービー リサーチ ファウンデーション 免疫原性ＰｃｐＡポリペプチドおよびその使用
RU2510281C2 (ru) * 2012-06-22 2014-03-27 Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА
GB201318170D0 (en) * 2013-10-14 2013-11-27 Univ Edinburgh Proteins with Diagnostic and Therapeutic Uses
KR101627285B1 (ko) * 2014-06-05 2016-06-07 한국생명공학연구원 ＰｓｐＡ를 유효성분으로 포함하는 퇴행성 뇌질환의 예방 또는 치료용 약학 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5854416A (en) * 1991-11-14 1998-12-29 The United States Of America As Represented By The Department Of Health And Human Services Streptococcus pneumoniae 37-KDA surface adhesin a protein and nucleic acids coding therefor
WO1994014318A1 (en) * 1992-12-24 1994-07-07 Medimmune, Inc. Method of protection against streptococcus pneumoniae with transformed mycobacteria
CA2326408A1 (en) * 1998-03-02 1999-09-10 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Epitope peptides immunogenic against streptococcus pneumoniae
CA2328399A1 (en) * 1998-04-23 1999-10-28 University Of Alabama At Birmingham Pneumococcal surface protein c(pspc), epitopic regions and strain selection thereof, and uses therefor

Also Published As

Publication number Publication date
WO2000076541A1 (en) 2000-12-21
EP1189632A4 (en) 2002-08-21
BR0011478A (pt) 2002-03-19
AU6121000A (en) 2001-01-02
MXPA01012721A (es) 2004-10-14
EP1189632A1 (en) 2002-03-27
JP2003519089A (ja) 2003-06-17

Similar Documents

Publication Publication Date Title
AU726927B2 (en) Strain selection of pneumococcal surface proteins
AU770378B2 (en) Pneumococcal surface protein C(PspC), epitopic regions and strain selection thereof, and uses therefor
US7960535B2 (en) Recombinant lipidated PsaA protein, methods of preparation and use
CN103501809B (zh) 针对肺炎链球菌（Streptococcus Pneumoniae）的疫苗和组合物
JP2017160238A (ja) ストレプトコッカス・ニューモニエ（Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅ）に対する融合抗原ワクチンおよび組成物
EP0682950B1 (en) Mucosal administration of pneumococcal antigens
CA2379327A1 (en) Pneumococcal surface protein combination vaccine
US8518415B2 (en) Engineered type IV pilin of Clostridium difficile
US20030059438A1 (en) Pneumococcal surface protein c (pspc), epitopic regions and strain selection thereof, and uses therefor
US6232116B1 (en) Oral administration of pneumococcal antigens
US6231870B1 (en) Oral administration of pneumoccal antigens
US20010016200A1 (en) Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US6004802A (en) Oral administration of pneumococcal antigens
RU2701733C1 (ru) Живая вакцина на основе штамма пробиотиков ENTEROCOCCUS FAECIUM L3 для профилактики инфекции, вызванной STREPTOCOCCUS PNEUMONIE
AU709368B2 (en) Oral administration of pneumococcal antigens
AU734488B2 (en) Mucosal administration of pneumococcal antigens
CN105131093A (zh) 一种肺炎链球菌蛋白抗原及其制备与应用
EP1194187A1 (en) Antibody-based treatment for streptococcus pneumoniae infection

Legal Events

Date Code Title Description
FZDE Discontinued