CA2373026C - Viral expression vectors - Google Patents
Viral expression vectors Download PDFInfo
- Publication number
- CA2373026C CA2373026C CA2373026A CA2373026A CA2373026C CA 2373026 C CA2373026 C CA 2373026C CA 2373026 A CA2373026 A CA 2373026A CA 2373026 A CA2373026 A CA 2373026A CA 2373026 C CA2373026 C CA 2373026C
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- Prior art keywords
- protein
- viral
- nucleic acid
- vector
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
- C12N15/8203—Virus mediated transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/00041—Use of virus, viral particle or viral elements as a vector
- C12N2770/00043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13269799P | 1999-05-04 | 1999-05-04 | |
| US60/132,697 | 1999-05-04 | ||
| PCT/US2000/012380 WO2000066743A2 (en) | 1999-05-04 | 2000-05-04 | Viral expression vectors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2373026A1 CA2373026A1 (en) | 2000-11-09 |
| CA2373026C true CA2373026C (en) | 2011-05-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2373026A Expired - Lifetime CA2373026C (en) | 1999-05-04 | 2000-05-04 | Viral expression vectors |
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| Country | Link |
|---|---|
| US (2) | US6656726B1 (enExample) |
| EP (1) | EP1181372B1 (enExample) |
| JP (1) | JP4750285B2 (enExample) |
| KR (1) | KR20020000802A (enExample) |
| AT (1) | ATE442441T1 (enExample) |
| AU (1) | AU781020B2 (enExample) |
| BR (1) | BR0010222A (enExample) |
| CA (1) | CA2373026C (enExample) |
| DE (1) | DE60042922D1 (enExample) |
| ES (1) | ES2332982T3 (enExample) |
| IL (1) | IL146191A0 (enExample) |
| WO (1) | WO2000066743A2 (enExample) |
| ZA (1) | ZA200108528B (enExample) |
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| ATE442441T1 (de) | 1999-05-04 | 2009-09-15 | Kentucky Bioproc Llc | Virale expressionsvektoren für pflanzen |
| US20080160040A1 (en) * | 2004-04-15 | 2008-07-03 | Ghim Shin-Je | Plant-produced compositions for treating papillomavirus infection and related methods |
| MY144766A (en) * | 2004-12-30 | 2011-10-31 | Schering Plough Ltd | Plant virus coat fusion proteins with gdf8 epitopes and vaccines thereof |
| CA2621466A1 (en) * | 2005-09-08 | 2007-04-05 | Kentucky Bioprocessing, Llc | Modified tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications |
| WO2008094512A2 (en) * | 2007-01-29 | 2008-08-07 | The Ohio Sate University Research Foundation | System for expression of genes in plants from a virus-based expression vector |
| WO2014097733A1 (ja) * | 2012-12-21 | 2014-06-26 | 株式会社ＵｎｉＢｉｏ | ヒト上皮細胞増殖因子の製造方法 |
| US11820988B2 (en) * | 2019-02-28 | 2023-11-21 | Purdue Research Foundation | Nanoparticles and biotemplates with tunable length and methods of manufacturing the same |
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| US5977438A (en) | 1988-02-26 | 1999-11-02 | Biosource Technologies, Inc. | Production of peptides in plants as viral coat protein fusions |
| US5316931A (en) | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5412087A (en) | 1992-04-24 | 1995-05-02 | Affymax Technologies N.V. | Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces |
| IL108241A (en) | 1992-12-30 | 2000-08-13 | Biosource Genetics Corp | Plant expression system comprising a defective tobamovirus replicon integrated into the plant chromosome and a helper virus |
| WO1995021248A1 (en) | 1994-02-03 | 1995-08-10 | The Scripps Research Institute | Method for using tobacco mosaic virus to overproduce peptides and proteins |
| US5695937A (en) | 1995-09-12 | 1997-12-09 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
| US5816653A (en) | 1997-03-17 | 1998-10-06 | Schukra Of North America Ltd. | Apparatus and method for adjusting the position of a supporting element in a seat |
| ATE442441T1 (de) | 1999-05-04 | 2009-09-15 | Kentucky Bioproc Llc | Virale expressionsvektoren für pflanzen |
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2000
- 2000-05-04 AT AT00930426T patent/ATE442441T1/de not_active IP Right Cessation
- 2000-05-04 US US09/565,616 patent/US6656726B1/en not_active Expired - Lifetime
- 2000-05-04 IL IL14619100A patent/IL146191A0/xx unknown
- 2000-05-04 DE DE60042922T patent/DE60042922D1/de not_active Expired - Lifetime
- 2000-05-04 JP JP2000615766A patent/JP4750285B2/ja not_active Expired - Lifetime
- 2000-05-04 EP EP00930426A patent/EP1181372B1/en not_active Expired - Lifetime
- 2000-05-04 BR BR0010222-9A patent/BR0010222A/pt not_active Application Discontinuation
- 2000-05-04 CA CA2373026A patent/CA2373026C/en not_active Expired - Lifetime
- 2000-05-04 AU AU48247/00A patent/AU781020B2/en not_active Ceased
- 2000-05-04 WO PCT/US2000/012380 patent/WO2000066743A2/en not_active Ceased
- 2000-05-04 KR KR1020017014002A patent/KR20020000802A/ko not_active Withdrawn
- 2000-05-04 ES ES00930426T patent/ES2332982T3/es not_active Expired - Lifetime
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2001
- 2001-10-17 ZA ZA200108528A patent/ZA200108528B/en unknown
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2003
- 2003-07-21 US US10/624,193 patent/US7132588B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2373026A1 (en) | 2000-11-09 |
| WO2000066743A2 (en) | 2000-11-09 |
| ES2332982T3 (es) | 2010-02-16 |
| AU4824700A (en) | 2000-11-17 |
| AU781020B2 (en) | 2005-04-28 |
| WO2000066743A3 (en) | 2001-04-26 |
| BR0010222A (pt) | 2002-03-19 |
| KR20020000802A (ko) | 2002-01-05 |
| US7132588B2 (en) | 2006-11-07 |
| US20050175590A1 (en) | 2005-08-11 |
| US6656726B1 (en) | 2003-12-02 |
| ZA200108528B (en) | 2002-10-17 |
| DE60042922D1 (de) | 2009-10-22 |
| JP2002542828A (ja) | 2002-12-17 |
| ATE442441T1 (de) | 2009-09-15 |
| WO2000066743A9 (en) | 2002-03-14 |
| EP1181372B1 (en) | 2009-09-09 |
| JP4750285B2 (ja) | 2011-08-17 |
| EP1181372A2 (en) | 2002-02-27 |
| IL146191A0 (en) | 2002-07-25 |
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