CA2372095A1 - Gene derive de $i(lawsonia) et polypeptides, peptides et proteines sodc associes, et leurs utilisations - Google Patents
Gene derive de $i(lawsonia) et polypeptides, peptides et proteines sodc associes, et leurs utilisations Download PDFInfo
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- CA2372095A1 CA2372095A1 CA002372095A CA2372095A CA2372095A1 CA 2372095 A1 CA2372095 A1 CA 2372095A1 CA 002372095 A CA002372095 A CA 002372095A CA 2372095 A CA2372095 A CA 2372095A CA 2372095 A1 CA2372095 A1 CA 2372095A1
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- Prior art keywords
- polypeptide
- amino acid
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- isolated
- intracellularis
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- 229910000489 osmium tetroxide Inorganic materials 0.000 description 1
- 239000012285 osmium tetroxide Substances 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 230000007030 peptide scission Effects 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 229940023041 peptide vaccine Drugs 0.000 description 1
- 210000005105 peripheral blood lymphocyte Anatomy 0.000 description 1
- 238000002823 phage display Methods 0.000 description 1
- 229960003742 phenol Drugs 0.000 description 1
- 230000008488 polyadenylation Effects 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000004481 post-translational protein modification Effects 0.000 description 1
- 230000001124 posttranscriptional effect Effects 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
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- 230000002035 prolonged effect Effects 0.000 description 1
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- 230000002285 radioactive effect Effects 0.000 description 1
- 230000008707 rearrangement Effects 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
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- 238000005215 recombination Methods 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000003362 replicative effect Effects 0.000 description 1
- 238000004366 reverse phase liquid chromatography Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
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- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
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- 229940075582 sorbic acid Drugs 0.000 description 1
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- 238000001228 spectrum Methods 0.000 description 1
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- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 108010061238 threonyl-glycine Proteins 0.000 description 1
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- 239000010937 tungsten Substances 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La présente invention porte en général sur des compositions thérapeutiques utilisées dans le traitement et/ou la prophylaxie des maladies intestinales chez les animaux et les oiseaux provoquées ou exacerbées par Lawsonia intracellularis ou similaire ou autre micro-organisme apparenté. Cette invention porte notamment sur un nouveau gène dérivé de Lawsonia intracellularis qui code un peptide, polypeptide ou protéine SodC immunogénique qui est notamment utile comme antigène dans la préparation de vaccins en vue de conférer l'immunité humorale contre Lawsonia intracellularis et des agents pathogènes apparentés chez des animaux hôtes. Cette invention porte également sur des procédés de traitement et/ou prophylaxie de ces maladies intestinales, ainsi que sur des agents diagnostiques et sur des procédures de détection de Lawsonia intracellularis ou similaire ou autres micro-organismes apparentés.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13398999P | 1999-05-13 | 1999-05-13 | |
| US60/133,989 | 1999-05-13 | ||
| PCT/AU2000/000436 WO2000069903A1 (fr) | 1999-05-13 | 2000-05-11 | Gene derive de $i(lawsonia) et polypeptides, peptides et proteines sodc associes, et leurs utilisations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2372095A1 true CA2372095A1 (fr) | 2000-11-23 |
Family
ID=22461256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002372095A Abandoned CA2372095A1 (fr) | 1999-05-13 | 2000-05-11 | Gene derive de $i(lawsonia) et polypeptides, peptides et proteines sodc associes, et leurs utilisations |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1177212A4 (fr) |
| JP (1) | JP2003501013A (fr) |
| AR (1) | AR023975A1 (fr) |
| AU (1) | AU4385800A (fr) |
| BR (1) | BR0011292A (fr) |
| CA (1) | CA2372095A1 (fr) |
| MX (1) | MXPA01011670A (fr) |
| NZ (1) | NZ515332A (fr) |
| PE (1) | PE20010238A1 (fr) |
| WO (1) | WO2000069903A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6605696B1 (en) | 1999-10-22 | 2003-08-12 | Pfizer, Inc. | Lawsonia intracellularis proteins, and related methods and materials |
| DE60120621T2 (de) | 2000-12-20 | 2006-12-14 | Intervet International B. V. | Lawsonia intracellularis Impfstoff |
| KR20060129163A (ko) * | 2003-09-12 | 2006-12-15 | 악조 노벨 엔.브이. | 로소니아 인트라셀룰라리스 서브유닛 백신 |
| KR20060134054A (ko) | 2004-01-22 | 2006-12-27 | 인터벳 인터내셔널 비.브이. | 로소니아 인트라셀룰라리스 서브유닛 백신 |
| US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
| US8398994B2 (en) | 2005-07-15 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Lawsonia vaccine and methods of use thereof |
| WO2008073464A2 (fr) | 2006-12-11 | 2008-06-19 | Boehringer Ingelheim Vetmedica, Inc. | Procédé efficace de traitement du circovirus porcin et des infections par lawsonia intracellularis |
| CN111830257B (zh) * | 2020-07-17 | 2023-10-24 | 南京农业大学 | 一种猪源胞内劳森菌ipma抗原检测方法及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5885823A (en) * | 1995-06-05 | 1999-03-23 | Nobl Laboratories, Inc. | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
| US7022328B1 (en) * | 1995-11-30 | 2006-04-04 | Australian Pork Limited | Therapeutic and diagnostic compositions |
-
2000
- 2000-05-11 CA CA002372095A patent/CA2372095A1/fr not_active Abandoned
- 2000-05-11 AU AU43858/00A patent/AU4385800A/en not_active Abandoned
- 2000-05-11 JP JP2000618319A patent/JP2003501013A/ja active Pending
- 2000-05-11 BR BR0011292-5A patent/BR0011292A/pt not_active IP Right Cessation
- 2000-05-11 EP EP00924975A patent/EP1177212A4/fr not_active Withdrawn
- 2000-05-11 MX MXPA01011670A patent/MXPA01011670A/es unknown
- 2000-05-11 NZ NZ515332A patent/NZ515332A/xx unknown
- 2000-05-11 WO PCT/AU2000/000436 patent/WO2000069903A1/fr not_active Application Discontinuation
- 2000-05-12 PE PE2000000445A patent/PE20010238A1/es not_active Application Discontinuation
- 2000-05-12 AR ARP000102294A patent/AR023975A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA01011670A (es) | 2003-10-14 |
| BR0011292A (pt) | 2002-02-26 |
| NZ515332A (en) | 2004-01-30 |
| EP1177212A1 (fr) | 2002-02-06 |
| PE20010238A1 (es) | 2001-03-03 |
| JP2003501013A (ja) | 2003-01-14 |
| WO2000069903A1 (fr) | 2000-11-23 |
| AR023975A1 (es) | 2002-09-04 |
| EP1177212A4 (fr) | 2002-08-28 |
| AU4385800A (en) | 2000-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |