CA2359701A1 - Nucleic-acid binding proteins - Google Patents
Nucleic-acid binding proteins Download PDFInfo
- Publication number
- CA2359701A1 CA2359701A1 CA002359701A CA2359701A CA2359701A1 CA 2359701 A1 CA2359701 A1 CA 2359701A1 CA 002359701 A CA002359701 A CA 002359701A CA 2359701 A CA2359701 A CA 2359701A CA 2359701 A1 CA2359701 A1 CA 2359701A1
- Authority
- CA
- Canada
- Prior art keywords
- seq
- nuabp
- polynucleotide
- sequence
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 230000001737 promoting effect Effects 0.000 description 1
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- XJMOSONTPMZWPB-UHFFFAOYSA-M propidium iodide Chemical compound [I-].[I-].C12=CC(N)=CC=C2C2=CC=C(N)C=C2[N+](CCC[N+](C)(CC)CC)=C1C1=CC=CC=C1 XJMOSONTPMZWPB-UHFFFAOYSA-M 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
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- 238000004445 quantitative analysis Methods 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000000163 radioactive labelling Methods 0.000 description 1
- 239000011535 reaction buffer Substances 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 1
- 125000006853 reporter group Chemical group 0.000 description 1
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- 239000011369 resultant mixture Substances 0.000 description 1
- 210000001995 reticulocyte Anatomy 0.000 description 1
- 238000010839 reverse transcription Methods 0.000 description 1
- 239000002336 ribonucleotide Substances 0.000 description 1
- 125000002652 ribonucleotide group Chemical group 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000013391 scatchard analysis Methods 0.000 description 1
- 238000010187 selection method Methods 0.000 description 1
- 239000006152 selective media Substances 0.000 description 1
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- 235000011803 sesame oil Nutrition 0.000 description 1
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- 238000002741 site-directed mutagenesis Methods 0.000 description 1
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- 108091029842 small nuclear ribonucleic acid Proteins 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
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- 229940005550 sodium alginate Drugs 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
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- 239000003826 tablet Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 231100001274 therapeutic index Toxicity 0.000 description 1
- 238000005382 thermal cycling Methods 0.000 description 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 description 1
- 229940094937 thioredoxin Drugs 0.000 description 1
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- 229940113082 thymine Drugs 0.000 description 1
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- 238000012090 tissue culture technique Methods 0.000 description 1
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- 239000004408 titanium dioxide Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
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- 230000032258 transport Effects 0.000 description 1
- 230000017105 transposition Effects 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 108700004896 tripeptide FEG Proteins 0.000 description 1
- 101150081616 trpB gene Proteins 0.000 description 1
- 101150111232 trpB-1 gene Proteins 0.000 description 1
- 108010080629 tryptophan-leucine Proteins 0.000 description 1
- 108010084932 tryptophyl-proline Proteins 0.000 description 1
- 108010038745 tryptophylglycine Proteins 0.000 description 1
- 108010045269 tryptophyltryptophan Proteins 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 108010017949 tyrosyl-glycyl-glycine Proteins 0.000 description 1
- 108010071635 tyrosyl-prolyl-arginine Proteins 0.000 description 1
- 108010003137 tyrosyltyrosine Proteins 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 241000701366 unidentified nuclear polyhedrosis viruses Species 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 description 1
- 229940045145 uridine Drugs 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- IBIDRSSEHFLGSD-UHFFFAOYSA-N valinyl-arginine Natural products CC(C)C(N)C(=O)NC(C(O)=O)CCCN=C(N)N IBIDRSSEHFLGSD-UHFFFAOYSA-N 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
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- 235000012431 wafers Nutrition 0.000 description 1
- 108010027345 wheylin-1 peptide Proteins 0.000 description 1
- 108010000998 wheylin-2 peptide Proteins 0.000 description 1
- QAOHCFGKCWTBGC-QHOAOGIMSA-N wybutosine Chemical compound C1=NC=2C(=O)N3C(CC[C@H](NC(=O)OC)C(=O)OC)=C(C)N=C3N(C)C=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O QAOHCFGKCWTBGC-QHOAOGIMSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11790499P | 1999-01-29 | 1999-01-29 | |
US11790599P | 1999-01-29 | 1999-01-29 | |
US60/117,904 | 1999-01-29 | ||
US60/117,905 | 1999-01-29 | ||
PCT/US2000/002237 WO2000044900A2 (en) | 1999-01-29 | 2000-01-28 | Nucleic-acid binding proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2359701A1 true CA2359701A1 (en) | 2000-08-03 |
Family
ID=26815777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002359701A Abandoned CA2359701A1 (en) | 1999-01-29 | 2000-01-28 | Nucleic-acid binding proteins |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1144625A2 (ja) |
JP (1) | JP2003521231A (ja) |
AU (1) | AU2743400A (ja) |
CA (1) | CA2359701A1 (ja) |
WO (1) | WO2000044900A2 (ja) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020151696A1 (en) * | 2000-11-29 | 2002-10-17 | Millennium Pharmaceuticals, Inc. | 84242,8035, 55304, 52999, and 21999, novel human proteins and methods of use thereof |
EP1425289A4 (en) * | 2001-01-30 | 2004-10-13 | Regeneron Pharma | NOVEL NUCLEIC ACID AND POLYPEPTIDE MOLECULES |
US20030045680A1 (en) * | 2001-03-12 | 2003-03-06 | Praecis Pharmaceuticals Inc. | Peptidic modulators of the androgen receptor |
WO2003000279A1 (en) * | 2001-06-21 | 2003-01-03 | The Brigham And Women's Hospital, Inc. | GEMININ AND orc3N INHIBIT REPLICATION OF HERPESVIRUSES, PAPILLOMAVIRUSES, AND POLYOMAVIRUSES |
CA2399569A1 (en) | 2001-09-25 | 2003-03-25 | Yusuke Nakamura | Diagnostic markers and drug targets for treatment of cancer |
ATE356223T1 (de) | 2001-09-25 | 2007-03-15 | Japan President Univ Tokyo | Gen und protein mit bezug zu hepatozellulärem karzinom |
DE10212397A1 (de) | 2002-03-20 | 2003-10-16 | Universitaetsklinikum Freiburg | Repressor der Skelettmuskeldifferenzierung, dafür kodierende Nucleinsäure und dessen Verwendung in Diagnostik und Therapie |
WO2004072269A2 (en) * | 2003-02-12 | 2004-08-26 | Mayo Foundation For Medical Education And Research | Bex4 nucleic acids, polypeptides, and method of using |
ATE504648T1 (de) * | 2003-02-28 | 2011-04-15 | Oncotherapy Science Inc | Rna-interferenz für das gen znfn3a1 als verfahren zur hemmung des wachstums von krebszellen |
TWI350373B (en) | 2004-01-23 | 2011-10-11 | Oncotherapy Science Inc | Methods of detecting methyl transferase activity and methods of screening formethyl transferase activity modulators |
EP1866436A1 (en) | 2005-02-28 | 2007-12-19 | Oncotherapy Science, Inc. | Breast cancer related gene znfn3a1 |
TW200741009A (en) | 2005-07-01 | 2007-11-01 | Oncotherapy Science Inc | Methods of modulating SMYD3 for treatment of cancer |
EP2171082B1 (en) | 2007-06-14 | 2012-11-28 | Oncotherapy Science, Inc. | Methods of identifying agents that modulate methylation of vegfr1 by smyd3 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5206152A (en) * | 1988-04-08 | 1993-04-27 | Arch Development Corporation | Cloning and expression of early growth regulatory protein genes |
EP0679716A4 (en) * | 1993-11-12 | 1999-06-09 | Kenichi Matsubara | GENE SIGNATURE. |
US5856128A (en) * | 1996-08-15 | 1999-01-05 | Incyte Pharmaceuticals, Inc. | Human nucleic acid binding protein |
WO1999033982A2 (en) * | 1997-12-23 | 1999-07-08 | Chiron Corporation | Human genes and gene expression products i |
-
2000
- 2000-01-28 WO PCT/US2000/002237 patent/WO2000044900A2/en not_active Application Discontinuation
- 2000-01-28 JP JP2000596142A patent/JP2003521231A/ja active Pending
- 2000-01-28 AU AU27434/00A patent/AU2743400A/en not_active Abandoned
- 2000-01-28 CA CA002359701A patent/CA2359701A1/en not_active Abandoned
- 2000-01-28 EP EP00905810A patent/EP1144625A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1144625A2 (en) | 2001-10-17 |
WO2000044900A3 (en) | 2000-11-30 |
WO2000044900A2 (en) | 2000-08-03 |
JP2003521231A (ja) | 2003-07-15 |
AU2743400A (en) | 2000-08-18 |
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Legal Events
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