CA2358895A1 - Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists - Google Patents

Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists Download PDF

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Publication number
CA2358895A1
CA2358895A1 CA002358895A CA2358895A CA2358895A1 CA 2358895 A1 CA2358895 A1 CA 2358895A1 CA 002358895 A CA002358895 A CA 002358895A CA 2358895 A CA2358895 A CA 2358895A CA 2358895 A1 CA2358895 A1 CA 2358895A1
Authority
CA
Canada
Prior art keywords
compound
dihydro
vasopressin
methanone
pyrido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002358895A
Other languages
English (en)
French (fr)
Inventor
Robert John Steffan
Amedeo Arturo Failli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2358895A1 publication Critical patent/CA2358895A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA002358895A 1999-02-04 2000-01-13 Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists Abandoned CA2358895A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24468199A 1999-02-04 1999-02-04
US09/244,681 1999-02-04
PCT/US2000/000886 WO2000046225A2 (en) 1999-02-04 2000-01-13 Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists

Publications (1)

Publication Number Publication Date
CA2358895A1 true CA2358895A1 (en) 2000-08-10

Family

ID=22923710

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002358895A Abandoned CA2358895A1 (en) 1999-02-04 2000-01-13 Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists

Country Status (6)

Country Link
EP (1) EP1149097A2 (de)
JP (1) JP2002536375A (de)
CN (1) CN1339035A (de)
AU (1) AU2849600A (de)
CA (1) CA2358895A1 (de)
WO (1) WO2000046225A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201005623D0 (en) 2010-04-01 2010-05-19 Vantia Ltd New polymorph
WO2016089830A1 (en) * 2014-12-05 2016-06-09 Merck Sharp & Dohme Corp. Novel tricyclic compounds as inhibitors of mutant idh enzymes
WO2016089833A1 (en) 2014-12-05 2016-06-09 Merck Sharp & Dohme Corp. Novel tricyclic compounds as inhibitors of mutant idh enzymes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849735A (en) * 1995-01-17 1998-12-15 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
AU8592598A (en) * 1997-07-30 1999-02-22 Wyeth Tricyclic vasopressin agonists

Also Published As

Publication number Publication date
WO2000046225A3 (en) 2000-12-14
AU2849600A (en) 2000-08-25
CN1339035A (zh) 2002-03-06
EP1149097A2 (de) 2001-10-31
WO2000046225A2 (en) 2000-08-10
JP2002536375A (ja) 2002-10-29

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Legal Events

Date Code Title Description
FZDE Dead