CA2356390A1 - Synthetic peptide of regulatory virus protein r (vpr) of human immunodeficiency virus type 1 (hiv-1) and the utilization thereof - Google Patents
Synthetic peptide of regulatory virus protein r (vpr) of human immunodeficiency virus type 1 (hiv-1) and the utilization thereof Download PDFInfo
- Publication number
- CA2356390A1 CA2356390A1 CA002356390A CA2356390A CA2356390A1 CA 2356390 A1 CA2356390 A1 CA 2356390A1 CA 002356390 A CA002356390 A CA 002356390A CA 2356390 A CA2356390 A CA 2356390A CA 2356390 A1 CA2356390 A1 CA 2356390A1
- Authority
- CA
- Canada
- Prior art keywords
- vpr
- glu
- arg
- leu
- ile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 235000012907 honey Nutrition 0.000 description 1
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- DCKVNWZUADLDEH-UHFFFAOYSA-N sec-butyl acetate Chemical compound CCC(C)OC(C)=O DCKVNWZUADLDEH-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- AIDS & HIV (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19908752A DE19908752A1 (de) | 1999-02-19 | 1999-02-19 | Synthetische Peptide des regulatorischen Virusproteins R (Vpr) des Humanen Immundefizienzvirus Typ 1 |
| DE19908766A DE19908766C2 (de) | 1999-02-19 | 1999-02-19 | Verwendung synthetischer Vpr-Peptide des Humanen Immundefizienzvirus Typ 1 (HIV-1) zur Entwicklung von therapeutischen und diagnostischen Reagenzien |
| JP2000599775A JP2002540768A (ja) | 1999-02-19 | 2000-02-19 | ヒト免疫不全ウイルス１型（ＨＩＶ−１）ウイルス性調節タンパク質Ｒ（Ｖｐｒ）の合成ペプチドおよびその適用 |
| EP00918674A EP1155035A2 (de) | 1999-02-19 | 2000-02-19 | Synthetische peptide des regulatorischen virusproteins r (vpr) des humanen immundefizienzvirus typ 1 (hiv-1) und ihre verwendung |
| PCT/DE2000/000525 WO2000049038A2 (de) | 1999-02-19 | 2000-02-19 | Synthetische peptide des regulatorischen virusproteins r (vpr) des humanen immundefizienzvirus typ 1 (hiv-1) und ihre verwendung |
| CA002356390A CA2356390A1 (en) | 1999-02-19 | 2001-08-17 | Synthetic peptide of regulatory virus protein r (vpr) of human immunodeficiency virus type 1 (hiv-1) and the utilization thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19908752A DE19908752A1 (de) | 1999-02-19 | 1999-02-19 | Synthetische Peptide des regulatorischen Virusproteins R (Vpr) des Humanen Immundefizienzvirus Typ 1 |
| DE19908766A DE19908766C2 (de) | 1999-02-19 | 1999-02-19 | Verwendung synthetischer Vpr-Peptide des Humanen Immundefizienzvirus Typ 1 (HIV-1) zur Entwicklung von therapeutischen und diagnostischen Reagenzien |
| CA002356390A CA2356390A1 (en) | 1999-02-19 | 2001-08-17 | Synthetic peptide of regulatory virus protein r (vpr) of human immunodeficiency virus type 1 (hiv-1) and the utilization thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2356390A1 true CA2356390A1 (en) | 2003-02-17 |
Family
ID=27808200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002356390A Abandoned CA2356390A1 (en) | 1999-02-19 | 2001-08-17 | Synthetic peptide of regulatory virus protein r (vpr) of human immunodeficiency virus type 1 (hiv-1) and the utilization thereof |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1155035A2 (ja) |
| JP (1) | JP2002540768A (ja) |
| CA (1) | CA2356390A1 (ja) |
| WO (1) | WO2000049038A2 (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6664040B2 (en) | 2000-05-23 | 2003-12-16 | The Regents Of The University Of California | Compositions and methods for delivery of a molecule into a cell |
| IL149279A0 (en) * | 2002-04-22 | 2002-11-10 | Yissum Res Dev Co | Anti-nls substances and uses thereof in nuclear import inhibition |
| FR2860236B1 (fr) * | 2003-09-25 | 2006-01-06 | Theraptosis | Peptides possedant notamment une activite anti-angiogenique et leurs applications en therapeutique |
| WO2005103654A2 (fr) * | 2004-04-09 | 2005-11-03 | Bioalliance Pharma | Methode d’identification de composes actifs sur la replication du virus hiv. |
| JP2008001598A (ja) * | 2004-10-12 | 2008-01-10 | Institute Of Physical & Chemical Research | アポトーシス誘導物質を含む医薬組成物 |
| JP4769009B2 (ja) * | 2005-04-05 | 2011-09-07 | オリエンタル酵母工業株式会社 | Ｖｐｒ特異的モノクローナル抗体を産生するハイブリドーマを作製するためのＶｐｒ抗原、抗Ｖｐｒ特異的モノクローナル抗体産生ハイブリドーマとそのハイブリドーマの産生する抗Ｖｐｒ特異的モノクローナル抗体およびそれを利用したＶｐｒの免疫学的測定 |
| EP2392587B1 (en) * | 2006-03-10 | 2016-05-04 | Peptcell Limited | Peptide sequences and compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5580739A (en) | 1986-01-22 | 1996-12-03 | Institut Pasteur | Peptides of human immunodeficiency virus type 2 (HIV-2) and in vitro diagnostic methods and kits employing the peptides for the detection of HIV-2 |
| US5780238A (en) | 1993-12-15 | 1998-07-14 | The Trustees Of The University Of Pennsylvania | VPR receptor protein |
| CA2186398A1 (en) | 1994-03-25 | 1995-10-05 | Ahmed A. Azad | Vpr and vpx proteins of hiv |
| US5861161A (en) | 1994-09-07 | 1999-01-19 | Universite De Montreal | Chimeric proteins comprising a Vpr/Vpx virion incorporation domain for targeting into HIV-1 or HIV-2 virions |
| US5763190A (en) | 1994-09-21 | 1998-06-09 | The Trustees Of The University Of Pennsylvania | Methods for the identification of compounds capable of inducing the nuclear translocation of a receptor complex comprising the glucocoticoid receptor type II and viral protein R interacting protein |
| US5639619A (en) | 1994-10-13 | 1997-06-17 | Regents Of The University Of California | Screening assay for anti-HIV drugs using the Vpr gene |
| US6328976B1 (en) | 1997-04-04 | 2001-12-11 | Immune Response Corporation | Non-infectious, protease defective HIV particles and nucleic acid molecules encoding therefor |
-
2000
- 2000-02-19 JP JP2000599775A patent/JP2002540768A/ja active Pending
- 2000-02-19 WO PCT/DE2000/000525 patent/WO2000049038A2/de active Application Filing
- 2000-02-19 EP EP00918674A patent/EP1155035A2/de not_active Withdrawn
-
2001
- 2001-08-17 CA CA002356390A patent/CA2356390A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000049038A3 (de) | 2001-03-01 |
| WO2000049038A2 (de) | 2000-08-24 |
| WO2000049038A9 (de) | 2001-05-17 |
| EP1155035A2 (de) | 2001-11-21 |
| JP2002540768A (ja) | 2002-12-03 |
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