CA2351348A1 - Substituted benzo[de]isoquinoline-1,3-diones - Google Patents
Substituted benzo[de]isoquinoline-1,3-diones Download PDFInfo
- Publication number
- CA2351348A1 CA2351348A1 CA002351348A CA2351348A CA2351348A1 CA 2351348 A1 CA2351348 A1 CA 2351348A1 CA 002351348 A CA002351348 A CA 002351348A CA 2351348 A CA2351348 A CA 2351348A CA 2351348 A1 CA2351348 A1 CA 2351348A1
- Authority
- CA
- Canada
- Prior art keywords
- conh
- chz
- formula
- het
- nhz
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19940998A | 1998-11-25 | 1998-11-25 | |
| US09/199,409 | 1998-11-25 | ||
| US40099299A | 1999-09-21 | 1999-09-21 | |
| US09/400,992 | 1999-09-21 | ||
| PCT/EP1999/008560 WO2000031039A1 (en) | 1998-11-25 | 1999-11-09 | Substituted benzo[de]isoquinoline-1,3-diones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2351348A1 true CA2351348A1 (en) | 2000-06-02 |
Family
ID=26894739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002351348A Abandoned CA2351348A1 (en) | 1998-11-25 | 1999-11-09 | Substituted benzo[de]isoquinoline-1,3-diones |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1133475A1 (pt) |
| JP (1) | JP2002530379A (pt) |
| CN (1) | CN1328549A (pt) |
| AR (1) | AR029152A1 (pt) |
| AU (1) | AU1504900A (pt) |
| BR (1) | BR9915611A (pt) |
| CA (1) | CA2351348A1 (pt) |
| CZ (1) | CZ20011792A3 (pt) |
| HU (1) | HUP0104469A3 (pt) |
| ID (1) | ID29425A (pt) |
| MX (1) | MXPA01005228A (pt) |
| NO (1) | NO20012543D0 (pt) |
| PL (1) | PL347766A1 (pt) |
| SK (1) | SK7012001A3 (pt) |
| WO (1) | WO2000031039A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0104236D0 (en) | 2001-02-21 | 2001-04-11 | Clariant Int Ltd | New dye compounds |
| GB0104240D0 (en) | 2001-02-21 | 2001-04-11 | Clariant Int Ltd | Copolymer composition having pigment like properties |
| GB0419850D0 (en) * | 2004-09-07 | 2004-10-13 | Angeletti P Ist Richerche Bio | Therapeutic agents |
| US8097725B2 (en) | 2004-12-03 | 2012-01-17 | Roche Diagnostics Operations, Inc. | Luminescent indicator dye and optical sensor |
| WO2012115945A1 (en) * | 2011-02-21 | 2012-08-30 | The Board Of Regents Of The University Of Texas System | Viral inhibitors |
| CN103848787A (zh) * | 2012-12-06 | 2014-06-11 | 中国科学院大连化学物理研究所 | 一种荧光探针及其在可逆检测次氯酸中的应用 |
| EP3348555B1 (en) | 2013-03-15 | 2020-11-25 | Alumend, LLC | Compositions and methods of using the compositions for plaque softening |
| WO2014179567A2 (en) * | 2013-05-01 | 2014-11-06 | Academia Sinica | Methods and compositions for treating beta-thalassemia and sickle cell disease |
| WO2018212355A1 (ja) * | 2017-05-19 | 2018-11-22 | 株式会社同仁化学研究所 | 蛍光化合物及びそれを用いたオートファジー検出試薬 |
| CN111253368B (zh) * | 2018-11-30 | 2020-12-25 | 沈阳药科大学 | 一类稳定氮氧自由基修饰的萘酰亚胺类化合物及其应用 |
| CN111777557B (zh) * | 2020-07-28 | 2022-11-22 | 中国科学院上海有机化学研究所 | 以芳香联苯烯为骨架的新型抗肿瘤先导化合物及其应用 |
| CN113087702B (zh) * | 2021-03-29 | 2022-07-12 | 苏州大学 | 一种多功能过氯乙烯衍生物及其制备方法与应用 |
| WO2023166531A1 (en) * | 2022-03-04 | 2023-09-07 | Jawaharlal Nehru Centre For Advanced Scientific Research | Amyloid and associated pathology modulators and methods thereof |
| WO2024042539A1 (en) * | 2022-08-22 | 2024-02-29 | Jawaharlal Nehru Centre For Advanced Scientific Research | Modulators of tau liquid-liquid phase separation and methods thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
| DE2360705A1 (de) * | 1973-12-06 | 1975-06-26 | Hoechst Ag | Wasserunloesliche verbindungen, verfahren zu ihrer herstellung und ihre verwendung als farbstoffe |
| US4200752A (en) * | 1978-02-16 | 1980-04-29 | Bertelson Robert C | 4-Disubstituted amino, N-substituted naphthalimide dyestuffs |
| JPS54160977A (en) * | 1978-06-09 | 1979-12-20 | Kawasaki Steel Corp | Functioning speed changing method by means of operating lever |
| GB2183667B (en) * | 1985-10-29 | 1989-11-22 | Univ Brunel | Preparation of amino-1;8-naphthalimides. |
| DE3614414A1 (de) * | 1986-04-29 | 1987-11-05 | Knoll Ag | Neue benzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung |
| US5308773A (en) * | 1992-11-16 | 1994-05-03 | Microbiomed Corp. | Non-azo 1,8-naphthalimide dyes for the detection and quantitation of a paramagnetic metal cation in a non-aqueous medium |
| DE19505941A1 (de) * | 1995-02-21 | 1996-08-22 | Bayer Ag | 1,8-Naphthalimid-Derivate, Verfahren zur Herstellung und ihre Verwendung als Zwischenprodukte |
| DK0930883T3 (da) * | 1996-10-21 | 2006-05-22 | Nps Allelix Corp | Neurotrofinantagonister til behandling af epilepsi, Alzheimers sygdom og smerte |
-
1999
- 1999-11-09 EP EP99957291A patent/EP1133475A1/en not_active Withdrawn
- 1999-11-09 CN CN99813608A patent/CN1328549A/zh active Pending
- 1999-11-09 CZ CZ20011792A patent/CZ20011792A3/cs unknown
- 1999-11-09 CA CA002351348A patent/CA2351348A1/en not_active Abandoned
- 1999-11-09 JP JP2000583867A patent/JP2002530379A/ja active Pending
- 1999-11-09 MX MXPA01005228A patent/MXPA01005228A/es unknown
- 1999-11-09 BR BR9915611-3A patent/BR9915611A/pt not_active IP Right Cessation
- 1999-11-09 SK SK701-2001A patent/SK7012001A3/sk unknown
- 1999-11-09 HU HU0104469A patent/HUP0104469A3/hu unknown
- 1999-11-09 WO PCT/EP1999/008560 patent/WO2000031039A1/en not_active Application Discontinuation
- 1999-11-09 ID IDW00200101390A patent/ID29425A/id unknown
- 1999-11-09 PL PL99347766A patent/PL347766A1/xx unknown
- 1999-11-09 AU AU15049/00A patent/AU1504900A/en not_active Abandoned
- 1999-11-24 AR ARP990105972A patent/AR029152A1/es not_active Application Discontinuation
-
2001
- 2001-05-23 NO NO20012543A patent/NO20012543D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL347766A1 (en) | 2002-04-22 |
| WO2000031039A1 (en) | 2000-06-02 |
| HUP0104469A2 (hu) | 2002-04-29 |
| CZ20011792A3 (cs) | 2001-09-12 |
| ID29425A (id) | 2001-08-30 |
| HUP0104469A3 (en) | 2003-06-30 |
| AU1504900A (en) | 2000-06-13 |
| NO20012543L (no) | 2001-05-23 |
| BR9915611A (pt) | 2001-08-14 |
| AR029152A1 (es) | 2003-06-18 |
| SK7012001A3 (en) | 2001-11-06 |
| EP1133475A1 (en) | 2001-09-19 |
| MXPA01005228A (es) | 2002-06-21 |
| NO20012543D0 (no) | 2001-05-23 |
| JP2002530379A (ja) | 2002-09-17 |
| CN1328549A (zh) | 2001-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |