CA2350829A1 - Transfection of male germ cells for generation of selectable transgenic stem cells - Google Patents

Transfection of male germ cells for generation of selectable transgenic stem cells Download PDF

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Publication number
CA2350829A1
CA2350829A1 CA002350829A CA2350829A CA2350829A1 CA 2350829 A1 CA2350829 A1 CA 2350829A1 CA 002350829 A CA002350829 A CA 002350829A CA 2350829 A CA2350829 A CA 2350829A CA 2350829 A1 CA2350829 A1 CA 2350829A1
Authority
CA
Canada
Prior art keywords
stem cell
transgenic
cell
vertebrate
promoter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002350829A
Other languages
English (en)
French (fr)
Inventor
Carol W. Readhead
Robert Winston
H. Phillip Koeffler
Carsten Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial College of Science Technology and Medicine
Cedars Sinai Medical Center
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1998/024238 external-priority patent/WO1999025863A1/en
Application filed by Individual filed Critical Individual
Publication of CA2350829A1 publication Critical patent/CA2350829A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0608Germ cells
    • C12N5/061Sperm cells, spermatogonia
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002350829A 1998-11-13 1999-04-15 Transfection of male germ cells for generation of selectable transgenic stem cells Abandoned CA2350829A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
USPCT/US98/24238 1998-11-13
PCT/US1998/024238 WO1999025863A1 (en) 1997-11-14 1998-11-13 Transfection and transfer of male germ cells for generation of transgenic species
US09/191,920 US6316692B1 (en) 1997-11-14 1998-11-13 Transfection, storage and transfer of male germ cells for generation of transgenic species and genetic therapies
US09/191,920 1998-11-13
PCT/US1999/008277 WO2000029602A1 (en) 1998-11-13 1999-04-15 Transfection of male germ cells for generation of selectable transgenic stem cells

Publications (1)

Publication Number Publication Date
CA2350829A1 true CA2350829A1 (en) 2000-05-25

Family

ID=26794482

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002350829A Abandoned CA2350829A1 (en) 1998-11-13 1999-04-15 Transfection of male germ cells for generation of selectable transgenic stem cells

Country Status (5)

Country Link
EP (1) EP1129205A1 (ja)
JP (1) JP2003526326A (ja)
AU (1) AU3563499A (ja)
CA (1) CA2350829A1 (ja)
WO (1) WO2000029602A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7696404B2 (en) 1996-08-19 2010-04-13 Advanced Cell Technology, Inc. Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
US7294755B1 (en) 1997-11-14 2007-11-13 Cedars-Sinai Medical Center Genetic modification of male germ cells for generation of transgenic species and genetic therapies
AU3391300A (en) * 1999-03-02 2000-09-21 University Of Massachusetts Embryonic or stem-like cell lines produced by cross species nuclear transplantation
CA2368620A1 (en) * 1999-05-13 2000-11-23 Cedars-Sinai Medical Center Genetic modification of male germ cells for generation of transgenic species and genetic therapies
US7053187B2 (en) * 2000-03-28 2006-05-30 Gioagri Corporation Sperm-specific monoclonal antibody, mAbC
KR100569168B1 (ko) * 2003-08-08 2006-04-07 (주)아비코아생명공학연구소 조류 정원줄기세포의 배양방법 및 이에 의해 수득한 조류정원줄기세포
GB0325140D0 (en) * 2003-10-28 2003-12-03 Babraham Inst Methods for selecting gametes and for producing genetically modified non-human animals
US20140359795A1 (en) * 2013-05-31 2014-12-04 Recombinetics, Inc. Genetic techniques for making animals with sortable sperm
US20140378755A1 (en) * 2013-06-20 2014-12-25 Elwha Llc Rapid breeding of animals
US9681615B2 (en) 2013-06-20 2017-06-20 Elwha Llc Rapid breeding of plants
CN105900922A (zh) * 2016-04-25 2016-08-31 固镇县益民养殖专业合作社 一种保健茶叶鸡的饲养方法
CN111838071B (zh) * 2020-08-07 2022-05-03 江苏省家禽科学研究所 具有黑尾和/或凤头性状的鸽的制种方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1228210B (it) * 1989-01-10 1991-06-05 Consiglio Nazionale Ricerche Procedimento per la introduzione di dna esogeno nelle cellule somatiche e germinali di animali.
US20030125519A1 (en) * 1990-08-27 2003-07-03 Peter Besmer Ligand for the c-kit receptor and methods of use thereof
JPH0591829A (ja) * 1991-09-27 1993-04-16 N T Sci:Kk 生物発光を触媒する酵素の遺伝子導入による形質転換動物
EP0619838A4 (en) * 1991-12-06 1996-04-17 Univ Pennsylvania Repopulation of testicular seminiferous tubules with foreign cells.
AU6498294A (en) * 1993-04-07 1994-10-24 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Dna sequence which acts as a chromatin insulator element to protect expressed genes from (cis)-acting regulatory sequences in mammalian cells
WO1995002041A1 (en) * 1993-07-09 1995-01-19 La Jolla Cancer Research Foundation Conditionally immortalized germ cell lines
JPH10304790A (ja) * 1995-09-29 1998-11-17 Hoechst Japan Ltd トランスジェニック動物の作成方法
JPH09220039A (ja) * 1996-02-14 1997-08-26 Chihiro Koike 精子又は卵子への外来遺伝子の導入方法及びトランスジェニック動物の作製方法
WO1998040468A1 (en) * 1997-03-13 1998-09-17 Vanderbilt University Methods of constructing a gene mutation library and compounds and compositions thereof

Also Published As

Publication number Publication date
WO2000029602A1 (en) 2000-05-25
AU3563499A (en) 2000-06-05
JP2003526326A (ja) 2003-09-09
EP1129205A1 (en) 2001-09-05

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