CA2344762C - Epreuves permettant une evaluation rapide d'etats ischemiques et necessaires a cet effet - Google Patents
Epreuves permettant une evaluation rapide d'etats ischemiques et necessaires a cet effet Download PDFInfo
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- CA2344762C CA2344762C CA002344762A CA2344762A CA2344762C CA 2344762 C CA2344762 C CA 2344762C CA 002344762 A CA002344762 A CA 002344762A CA 2344762 A CA2344762 A CA 2344762A CA 2344762 C CA2344762 C CA 2344762C
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Cette invention a trait à des méthodes permettant de détecter rapidement des états ischémiques ainsi qu'aux nécessaires utilisés à cet effet. Elle concerne également une méthode rapide de recherche et de quantification de l'ischémie, reposant sur des techniques de détection et de quantification de l'existence d'une modification de la sérumalbumine protéique survenant après une manifestation ischémique. Ces techniques de détection et de quantification consistent à évaluer et à quantifier la capacité de fixation du cobalt de l'albumine circulante, à analyser et à évaluer la capacité de la sérumalbumine à fixer du cobalt exogène, à détecter et à évaluer la présence de cuivre endogène dans un prélèvement d'albumine purifiée et à utiliser un dosage immunologique spécifique de la forme altérée de la sérumalbumine, forme découlant d'une manifestation ischémique. Cette invention porte, en outre, sur la détection et la mesure d'une manifestation ischémique par mesure de dérivés d'albumine à N-terminus se manifestant à la suite d'une manifestation ischémique, y compris des espèces tronquées d'albumine dépourvues de un à quatre acides aminés N-terminus ou de l'albumine porteuse d'un reste d'acide aspartique (Asp) N-terminus acétylé.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10273898P | 1998-10-02 | 1998-10-02 | |
US09/165,581 | 1998-10-02 | ||
US09/165,581 US6492179B1 (en) | 1998-10-02 | 1998-10-02 | Test for rapid evaluation of ischemic states and kit |
US60/102,738 | 1998-10-02 | ||
US09/165,926 US6461875B1 (en) | 1998-10-02 | 1998-10-02 | Test for rapid evaluation of ischemic states and kit |
US09/165,926 | 1998-10-02 | ||
US11539299P | 1999-01-11 | 1999-01-11 | |
US60/115,392 | 1999-01-11 | ||
PCT/US1999/022905 WO2000020840A1 (fr) | 1998-10-02 | 1999-10-01 | Epreuves permettant une evaluation rapide d'etats ischemiques et necessaires a cet effet |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2344762A1 CA2344762A1 (fr) | 2000-04-13 |
CA2344762C true CA2344762C (fr) | 2008-12-23 |
Family
ID=27493289
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002344762A Expired - Fee Related CA2344762C (fr) | 1998-10-02 | 1999-10-01 | Epreuves permettant une evaluation rapide d'etats ischemiques et necessaires a cet effet |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1125107A4 (fr) |
JP (1) | JP2002526764A (fr) |
AU (1) | AU769727B2 (fr) |
CA (1) | CA2344762C (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1571970B1 (fr) * | 2002-10-02 | 2011-08-17 | DMI Biosciences, Inc. | Diagnostic et controle de maladies |
CN101261270B (zh) * | 2007-03-09 | 2012-11-07 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种免疫层析多重检测试纸盘及免疫层析多重检测方法 |
EP1983345A1 (fr) * | 2007-04-17 | 2008-10-22 | Roche Diagnostics GmbH | Moyen et procédé pour l'évaluation du risque d'une intervention cardiaque chez des patients souffrant d'une maladie cardiaque coronarienne stable basés sur le GDF-15 |
EP3649474A1 (fr) * | 2017-07-03 | 2020-05-13 | Abbott Laboratories | Procédés améliorés de mesure de niveaux d'hydrolase à terminaison carboxy d'ubiquitine l1 dans le sang |
CN110132872A (zh) * | 2019-06-14 | 2019-08-16 | 湖北科艾乐检测科技有限公司 | 一种灌溉水水体重金属检测方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4492753A (en) * | 1982-10-06 | 1985-01-08 | Immudx, Inc. | Method and means for assessment and prediction of risk of subsequent ischemic cardiac events |
US5227307A (en) * | 1991-07-26 | 1993-07-13 | Diagnostic Markers, Inc. | Test for the rapid evaluation of ischemic state |
EP1117686B1 (fr) * | 1998-10-02 | 2008-07-16 | Ischemia Technologies, Inc. | Procedes et substances pour detecter et mesurer les lesions provoquees par des radicaux libres |
-
1999
- 1999-10-01 JP JP2000574907A patent/JP2002526764A/ja not_active Withdrawn
- 1999-10-01 EP EP99951710A patent/EP1125107A4/fr not_active Withdrawn
- 1999-10-01 AU AU64095/99A patent/AU769727B2/en not_active Ceased
- 1999-10-01 CA CA002344762A patent/CA2344762C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1125107A1 (fr) | 2001-08-22 |
EP1125107A4 (fr) | 2002-04-17 |
AU6409599A (en) | 2000-04-26 |
AU769727B2 (en) | 2004-02-05 |
JP2002526764A (ja) | 2002-08-20 |
CA2344762A1 (fr) | 2000-04-13 |
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