CA2341699A1 - A method for the treatment of staphylococcal disease - Google Patents
A method for the treatment of staphylococcal disease Download PDFInfo
- Publication number
- CA2341699A1 CA2341699A1 CA002341699A CA2341699A CA2341699A1 CA 2341699 A1 CA2341699 A1 CA 2341699A1 CA 002341699 A CA002341699 A CA 002341699A CA 2341699 A CA2341699 A CA 2341699A CA 2341699 A1 CA2341699 A1 CA 2341699A1
- Authority
- CA
- Canada
- Prior art keywords
- infection
- lysostaphin
- patient
- staphylococcal
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24075—Lysostaphin (3.4.24.75)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/140,732 US6028051A (en) | 1997-07-23 | 1998-08-27 | Method for the treatment of staphylococcal disease |
| US09/140,732 | 1998-08-27 | ||
| PCT/US1999/020396 WO2000012049A2 (en) | 1998-08-27 | 1999-08-27 | A method for the treatment of staphylococcal disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2341699A1 true CA2341699A1 (en) | 2000-03-09 |
Family
ID=22492556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002341699A Abandoned CA2341699A1 (en) | 1998-08-27 | 1999-08-27 | A method for the treatment of staphylococcal disease |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6028051A (https=) |
| EP (1) | EP1107722B1 (https=) |
| JP (1) | JP2002523437A (https=) |
| AR (1) | AR023645A1 (https=) |
| AT (1) | ATE493145T1 (https=) |
| AU (1) | AU5811199A (https=) |
| CA (1) | CA2341699A1 (https=) |
| DE (1) | DE69943089D1 (https=) |
| IL (1) | IL141648A0 (https=) |
| NO (1) | NO20010953L (https=) |
| WO (1) | WO2000012049A2 (https=) |
| ZA (1) | ZA995444B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7091332B1 (en) | 1998-06-22 | 2006-08-15 | University Of Vermont | Treatment of staphylococcus infections |
| US6875903B2 (en) * | 1998-06-22 | 2005-04-05 | University Of Vermont | Treatment of Staphylococcus infections |
| US6569830B1 (en) | 1999-03-05 | 2003-05-27 | Ambi, Inc. | Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains |
| EP1465990B1 (en) * | 2001-12-21 | 2011-07-13 | Biosynexus Incorporated | Truncated lysostaphin molecule with enhanced staphylolytic activity |
| US20030211995A1 (en) * | 2001-12-21 | 2003-11-13 | Kokai-Kun John Fitzgerald | Methods and formulations for eradicating or alleviating staphylococcal nasal colonization using lysostaphin |
| US6759881B2 (en) * | 2002-03-22 | 2004-07-06 | Rambus Inc. | System with phase jumping locked loop circuit |
| US7572439B2 (en) * | 2002-03-26 | 2009-08-11 | Biosynexus Incorporated | Enzyme disruption of bacterial biofilms |
| WO2003082926A2 (en) * | 2002-03-26 | 2003-10-09 | Biosynexus Incorporated | Antimicrobial polymer conjugates |
| AU2003296937A1 (en) * | 2002-12-10 | 2004-06-30 | Biosynexus Incorporated | Topical anti-infective formulations |
| US20100221237A1 (en) * | 2003-03-26 | 2010-09-02 | Biosynexus Incorporated | Enzyme disruption of bacterial biofilms |
| US20070190542A1 (en) * | 2005-10-03 | 2007-08-16 | Ling Xinsheng S | Hybridization assisted nanopore sequencing |
| US20080095756A1 (en) * | 2006-09-05 | 2008-04-24 | Biosynexus Incorporated | Compositions Comprising Lysostaphin Variants And Methods Of Using The Same |
| WO2009114520A2 (en) * | 2008-03-10 | 2009-09-17 | Pharmain Corporation | Compositions for treatment with metallopeptidases, methods of making and using the same |
| US20090304673A1 (en) * | 2008-06-10 | 2009-12-10 | Bernd Buchberger | Method of Treatment of Inflammatory Diseases |
| WO2015175774A1 (en) | 2014-05-14 | 2015-11-19 | Trustees Of Dartmouth College | Deimmunized lysostaphin and methods of use |
| RU2718554C1 (ru) | 2017-09-25 | 2020-04-08 | Георгий Георгиевич Чумбуридзе | Термостабильная композиция, обладающая антивирусной и антибактериальной активностью и ее использование |
| CA3120255A1 (en) * | 2018-11-19 | 2020-05-28 | Nordmark Ip Gmbh | Ancrod for the treatment or prophylaxis of endocarditis |
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|---|---|---|---|---|
| US3067099A (en) * | 1955-09-16 | 1962-12-04 | Lilly Co Eli | Vancomycin and method for its preparation |
| US4931390A (en) * | 1986-04-16 | 1990-06-05 | Public Health Research Institute Of The City Of New York, Inc. | Expression of the cloned lysostaphin gene |
| US5858962A (en) * | 1987-05-11 | 1999-01-12 | Ambi Inc. | Composition for treating mastitis and other staphylococcal infections |
| US4980163A (en) * | 1989-03-01 | 1990-12-25 | Public Health Research Institute Of The City Of New York | Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection |
| US5342612A (en) * | 1991-12-20 | 1994-08-30 | American Cyanamid Company | Compositions for the treatment of mammalian diseases |
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1998
- 1998-08-27 US US09/140,732 patent/US6028051A/en not_active Expired - Lifetime
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1999
- 1999-08-25 ZA ZA9905444A patent/ZA995444B/xx unknown
- 1999-08-26 AR ARP990104279A patent/AR023645A1/es unknown
- 1999-08-27 CA CA002341699A patent/CA2341699A1/en not_active Abandoned
- 1999-08-27 AU AU58111/99A patent/AU5811199A/en not_active Abandoned
- 1999-08-27 DE DE69943089T patent/DE69943089D1/de not_active Expired - Lifetime
- 1999-08-27 IL IL14164899A patent/IL141648A0/xx unknown
- 1999-08-27 EP EP99945525A patent/EP1107722B1/en not_active Expired - Lifetime
- 1999-08-27 AT AT99945525T patent/ATE493145T1/de not_active IP Right Cessation
- 1999-08-27 JP JP2000567170A patent/JP2002523437A/ja active Pending
- 1999-08-27 WO PCT/US1999/020396 patent/WO2000012049A2/en not_active Ceased
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2001
- 2001-02-26 NO NO20010953A patent/NO20010953L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1107722B1 (en) | 2010-12-29 |
| NO20010953D0 (no) | 2001-02-26 |
| IL141648A0 (en) | 2002-03-10 |
| ATE493145T1 (de) | 2011-01-15 |
| WO2000012049A2 (en) | 2000-03-09 |
| JP2002523437A (ja) | 2002-07-30 |
| AU5811199A (en) | 2000-03-21 |
| ZA995444B (en) | 2000-07-10 |
| DE69943089D1 (de) | 2011-02-10 |
| NO20010953L (no) | 2001-03-21 |
| EP1107722A4 (en) | 2006-05-17 |
| WO2000012049A3 (en) | 2000-05-25 |
| US6028051A (en) | 2000-02-22 |
| AR023645A1 (es) | 2002-09-04 |
| EP1107722A2 (en) | 2001-06-20 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |