CA2333702A1 - Promotion de la differenciation cellulaire par des cellules ayant subi initialement plusieurs passages - Google Patents

Promotion de la differenciation cellulaire par des cellules ayant subi initialement plusieurs passages Download PDF

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Publication number
CA2333702A1
CA2333702A1 CA002333702A CA2333702A CA2333702A1 CA 2333702 A1 CA2333702 A1 CA 2333702A1 CA 002333702 A CA002333702 A CA 002333702A CA 2333702 A CA2333702 A CA 2333702A CA 2333702 A1 CA2333702 A1 CA 2333702A1
Authority
CA
Canada
Prior art keywords
cells
passaged
islet
insulin
reaggregated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002333702A
Other languages
English (en)
Inventor
Ivan T. Todorov
Kelly I. Scheyhing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cythera Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2333702A1 publication Critical patent/CA2333702A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/22—Coculture with; Conditioned medium produced by pancreatic cells

Abstract

L'invention porte sur un procédé provoquant la différenciation de cellules ayant subi plusieurs passages moins différenciées en les mettant en contact avec des cellules du même type ayant subi initialement plusieurs passages (P0) et plus différenciées. Le procédé produit des agrégats de cellules différenciées tels que des agrégats de cellules d'îlots de Langherans utilisables pour des transplantations.
CA002333702A 1998-05-29 1999-05-28 Promotion de la differenciation cellulaire par des cellules ayant subi initialement plusieurs passages Abandoned CA2333702A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8768598A 1998-05-29 1998-05-29
US09/087,685 1998-05-29
PCT/US1999/011949 WO1999061586A1 (fr) 1998-05-29 1999-05-28 Promotion de la differenciation cellulaire par des cellules ayant subi initialement plusieurs passages

Publications (1)

Publication Number Publication Date
CA2333702A1 true CA2333702A1 (fr) 1999-12-02

Family

ID=22206656

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002333702A Abandoned CA2333702A1 (fr) 1998-05-29 1999-05-28 Promotion de la differenciation cellulaire par des cellules ayant subi initialement plusieurs passages

Country Status (5)

Country Link
EP (1) EP1080183A1 (fr)
AU (1) AU4544299A (fr)
CA (1) CA2333702A1 (fr)
IL (1) IL139883A0 (fr)
WO (1) WO1999061586A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759039B2 (en) 2000-06-30 2004-07-06 Amcyte, Inc. Culturing pancreatic stem cells having a specified, intermediate stage of development
US7101546B2 (en) 2001-12-21 2006-09-05 Amcyte, Inc. In situ maturation of cultured pancreatic stem cells having a specified, intermediate stage of development

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0273039A4 (fr) * 1986-04-03 1990-01-08 Univ East Carolina Procede utilisant la capacite d'induction d'une matrice extracellulaire pour produire des tissus d'ilots pancreatiques.
US5510263A (en) * 1993-04-05 1996-04-23 Desmos, Inc. Growth of pancreatic islet-like cell clusters
DE69637669D1 (de) * 1995-06-06 2008-10-16 Osiris Therapeutics Inc Myogene differenzierung menschlicher mesenchymaler stammzellen
US5681587A (en) * 1995-10-06 1997-10-28 Desmos, Inc. Growth of adult pancreatic islet cells
WO1997016536A1 (fr) * 1995-10-30 1997-05-09 Vivorx, Inc. Procede permettant une proliferation et une differentiation ex vivo de cellules des ilots pancreatiques adultes, milieux utiles pour ce procede et leurs utilisations

Also Published As

Publication number Publication date
WO1999061586A1 (fr) 1999-12-02
AU4544299A (en) 1999-12-13
WO1999061586A9 (fr) 2000-04-27
WO1999061586A8 (fr) 2000-03-09
EP1080183A1 (fr) 2001-03-07
IL139883A0 (en) 2002-02-10

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Legal Events

Date Code Title Description
FZDE Discontinued