CA2304381A1 - Milieu favorisant la survie des cellules insulaires - Google Patents

Milieu favorisant la survie des cellules insulaires Download PDF

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Publication number
CA2304381A1
CA2304381A1 CA002304381A CA2304381A CA2304381A1 CA 2304381 A1 CA2304381 A1 CA 2304381A1 CA 002304381 A CA002304381 A CA 002304381A CA 2304381 A CA2304381 A CA 2304381A CA 2304381 A1 CA2304381 A1 CA 2304381A1
Authority
CA
Canada
Prior art keywords
medium
islets
islet
islet cells
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002304381A
Other languages
English (en)
Inventor
Lawrence Rosenberg
Dusica Maysinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McGill University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2216055 external-priority patent/CA2216055A1/fr
Application filed by Individual filed Critical Individual
Priority to CA002304381A priority Critical patent/CA2304381A1/fr
Publication of CA2304381A1 publication Critical patent/CA2304381A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/22—Coculture with; Conditioned medium produced by pancreatic cells

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention porte sur un milieu de culture favorisant la survie des cellules insulaires mammaliennes, ce milieu comprenant au moins une quantité efficace d'un ou plusieurs facteurs de croissance ayant un effet anti-apoptose sur les cellules insulaires d'un milieu de culture physiologiquement acceptable.
CA002304381A 1997-09-19 1998-09-17 Milieu favorisant la survie des cellules insulaires Abandoned CA2304381A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002304381A CA2304381A1 (fr) 1997-09-19 1998-09-17 Milieu favorisant la survie des cellules insulaires

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA 2216055 CA2216055A1 (fr) 1997-09-19 1997-09-19 Milieu favorisant la survie des cellules secretrices d'insuline
CA2,216,055 1997-09-19
CA002304381A CA2304381A1 (fr) 1997-09-19 1998-09-17 Milieu favorisant la survie des cellules insulaires
PCT/CA1998/000887 WO1999015625A1 (fr) 1997-09-19 1998-09-17 Milieu favorisant la survie des cellules insulaires

Publications (1)

Publication Number Publication Date
CA2304381A1 true CA2304381A1 (fr) 1999-04-01

Family

ID=25679624

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002304381A Abandoned CA2304381A1 (fr) 1997-09-19 1998-09-17 Milieu favorisant la survie des cellules insulaires

Country Status (1)

Country Link
CA (1) CA2304381A1 (fr)

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Legal Events

Date Code Title Description
FZDE Discontinued