CA2326623A1 - Gene codant pour une proteine interagissant avec une syntaxine - Google Patents
Gene codant pour une proteine interagissant avec une syntaxine Download PDFInfo
- Publication number
- CA2326623A1 CA2326623A1 CA002326623A CA2326623A CA2326623A1 CA 2326623 A1 CA2326623 A1 CA 2326623A1 CA 002326623 A CA002326623 A CA 002326623A CA 2326623 A CA2326623 A CA 2326623A CA 2326623 A1 CA2326623 A1 CA 2326623A1
- Authority
- CA
- Canada
- Prior art keywords
- synip
- rna
- cells
- dna sequence
- isolated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Plant Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne de nouveaux gènes et des polypeptides dérivés codant pour une protéine interagissant avec une syntaxine. L'invention concerne également des vecteurs et des cellules hôtes comprenant ce nouveau gène, ainsi que des procédés d'utilisation du nouveau gène, des polypeptides et des anticorps ciblant spécifiquement les polypeptides dérivés de ces nouveaux gènes. Ces procédés permettent la détection de déficiences génétiques, la localisation sous-cellulaire du polypeptide, l'isolement de classes distinctes d'ARN, l'application de thérapies géniques, les diagnostics pour les syndromes faisant intervenir la résistance à l'insuline, la mise au point de stratégies de criblage de spécialités pour des inhibiteurs de la protéine interagissant avec la syntaxine.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8245498P | 1998-04-20 | 1998-04-20 | |
US60/082,454 | 1998-04-20 | ||
PCT/US1999/008568 WO1999054465A2 (fr) | 1998-04-20 | 1999-04-19 | Gene codant pour une proteine interagissant avec une syntaxine |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2326623A1 true CA2326623A1 (fr) | 1999-10-28 |
Family
ID=22171326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002326623A Abandoned CA2326623A1 (fr) | 1998-04-20 | 1999-04-19 | Gene codant pour une proteine interagissant avec une syntaxine |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1071771A2 (fr) |
JP (1) | JP2002512031A (fr) |
KR (1) | KR20010042834A (fr) |
AU (1) | AU769825B2 (fr) |
BR (1) | BR9909732A (fr) |
CA (1) | CA2326623A1 (fr) |
NZ (2) | NZ526016A (fr) |
WO (1) | WO1999054465A2 (fr) |
ZA (1) | ZA200005845B (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6503756B1 (en) | 2000-09-22 | 2003-01-07 | Isis Pharmaceuticals, Inc. | Antisense modulation of syntaxin 4 interacting protein expression |
WO2004053103A2 (fr) * | 2002-12-11 | 2004-06-24 | University Of Massachusetts | Procede d'introduction de sirna dans des adipocytes |
FR2890859B1 (fr) * | 2005-09-21 | 2012-12-21 | Oreal | Oligonucleotide d'arn double brin inhibant l'expression de la tyrosinase |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001519667A (ja) * | 1997-04-10 | 2001-10-23 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌発現配列タグ(sESTs) |
-
1999
- 1999-04-19 NZ NZ526016A patent/NZ526016A/en unknown
- 1999-04-19 CA CA002326623A patent/CA2326623A1/fr not_active Abandoned
- 1999-04-19 EP EP99918680A patent/EP1071771A2/fr not_active Withdrawn
- 1999-04-19 BR BR9909732-0A patent/BR9909732A/pt not_active IP Right Cessation
- 1999-04-19 WO PCT/US1999/008568 patent/WO1999054465A2/fr not_active Application Discontinuation
- 1999-04-19 JP JP2000544797A patent/JP2002512031A/ja active Pending
- 1999-04-19 KR KR1020007011597A patent/KR20010042834A/ko not_active Application Discontinuation
- 1999-04-19 NZ NZ507640A patent/NZ507640A/en unknown
- 1999-04-19 AU AU36535/99A patent/AU769825B2/en not_active Ceased
-
2000
- 2000-10-19 ZA ZA200005845A patent/ZA200005845B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO1999054465A2 (fr) | 1999-10-28 |
AU769825B2 (en) | 2004-02-05 |
WO1999054465A9 (fr) | 2000-01-27 |
KR20010042834A (ko) | 2001-05-25 |
EP1071771A2 (fr) | 2001-01-31 |
BR9909732A (pt) | 2000-12-19 |
JP2002512031A (ja) | 2002-04-23 |
AU3653599A (en) | 1999-11-08 |
NZ507640A (en) | 2003-12-19 |
ZA200005845B (en) | 2002-04-19 |
NZ526016A (en) | 2004-10-29 |
WO1999054465A3 (fr) | 2000-03-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |