CA2359145A1 - Proteine de voies d'exocytose et leurs procedes d'utilisation - Google Patents

Proteine de voies d'exocytose et leurs procedes d'utilisation Download PDF

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Publication number
CA2359145A1
CA2359145A1 CA002359145A CA2359145A CA2359145A1 CA 2359145 A1 CA2359145 A1 CA 2359145A1 CA 002359145 A CA002359145 A CA 002359145A CA 2359145 A CA2359145 A CA 2359145A CA 2359145 A1 CA2359145 A1 CA 2359145A1
Authority
CA
Canada
Prior art keywords
seq
leu
ser
protein
glu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002359145A
Other languages
English (en)
Inventor
Ying Luo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rigel Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2359145A1 publication Critical patent/CA2359145A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)

Abstract

La présente invention concerne de nouveaux polypeptides telles que l'exo-protéine et les molécules apparentées ayant une action sur/relative à l'exocytose et aux molécules d'acide nucléique codant ces polypeptides. En outre, cette invention concerne des vecteurs et des cellules hôtes contenant ces séquences d'acide nucléique, des molécules de polypeptides chimériques contenant les polypeptides précités accolés à des séquences polypeptidiques hétérologues, des anticorps se liant à ces polypeptides, ainsi que des procédés de production de ces polypeptides. En outre, cette invention concerne un procédé d'identification de nouvelles compositions permettant l'exo-bioactivité, et l'utilisation de ces compositions dans le diagnostic et le traitement de maladies.
CA002359145A 1999-01-20 2000-01-20 Proteine de voies d'exocytose et leurs procedes d'utilisation Abandoned CA2359145A1 (fr)

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
US11653499P 1999-01-20 1999-01-20
US60/116,534 1999-01-20
US11731299P 1999-01-26 1999-01-26
US11730899P 1999-01-26 1999-01-26
US11730999P 1999-01-26 1999-01-26
US11727499P 1999-01-26 1999-01-26
US60/117,274 1999-01-26
US60/117,308 1999-01-26
US60/117,309 1999-01-26
US60/117,312 1999-01-26
US11817899P 1999-02-01 1999-02-01
US11817999P 1999-02-01 1999-02-01
US11817799P 1999-02-01 1999-02-01
US60/118,179 1999-02-01
US60/118,177 1999-02-01
US60/118,178 1999-02-01
US11928699P 1999-02-09 1999-02-09
US60/119,286 1999-02-09
US11975999P 1999-02-11 1999-02-11
US11999899P 1999-02-11 1999-02-11
US60/119,759 1999-02-11
US60/119,998 1999-02-11
PCT/US2000/001431 WO2000043419A2 (fr) 1999-01-20 2000-01-20 Proteine de voies d'exocytose et leurs procedes d'utilisation

Publications (1)

Publication Number Publication Date
CA2359145A1 true CA2359145A1 (fr) 2000-07-27

Family

ID=27582648

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002359145A Abandoned CA2359145A1 (fr) 1999-01-20 2000-01-20 Proteine de voies d'exocytose et leurs procedes d'utilisation

Country Status (5)

Country Link
EP (1) EP1161442A2 (fr)
JP (1) JP2003521230A (fr)
AU (1) AU2416600A (fr)
CA (1) CA2359145A1 (fr)
WO (1) WO2000043419A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002952550A0 (en) * 2002-11-08 2002-11-21 The University Of Queensland Modulating TNFalpha Secretion
CN103237811A (zh) 2010-05-06 2013-08-07 诺瓦提斯公司 用于治疗性低密度脂蛋白相关蛋白质6(lrp6)多价抗体的组合物及使用方法
CA2798432A1 (fr) 2010-05-06 2011-11-10 Novartis Ag Compositions et procedes d'utilisation d'anticorps therapeutiques diriges contre la proteine 6 liee a la lipoproteine de basse densite (lrp6)
MX2014005411A (es) 2011-11-04 2015-02-12 Novartis Ag Construcciones prolongadas de la vida media de la proteina relacionada con lipoproteina de baja densidad 6 (lrp6).
CN116790760B (zh) * 2023-08-17 2023-12-12 北京大学人民医院 结肠癌特异性环状rna标记物及其检测引物与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998055152A1 (fr) * 1997-06-06 1998-12-10 Baylor College Of Medicine Mecanisme secretoire des mastocytes utilise comme cible en vue du developpement de medicaments antiallergiques
US6623980B1 (en) * 1998-02-23 2003-09-23 Rigel Pharmaceuticals, Inc. Exo1 and Exo2, exocytotic proteins

Also Published As

Publication number Publication date
AU2416600A (en) 2000-08-07
WO2000043419A2 (fr) 2000-07-27
WO2000043419A3 (fr) 2001-02-15
EP1161442A2 (fr) 2001-12-12
JP2003521230A (ja) 2003-07-15

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Legal Events

Date Code Title Description
FZDE Discontinued