CA2323574A1 - Identification d'un adnc associe a l'ischemie dans un tissu cardiaque humain - Google Patents

Identification d'un adnc associe a l'ischemie dans un tissu cardiaque humain Download PDF

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Publication number
CA2323574A1
CA2323574A1 CA002323574A CA2323574A CA2323574A1 CA 2323574 A1 CA2323574 A1 CA 2323574A1 CA 002323574 A CA002323574 A CA 002323574A CA 2323574 A CA2323574 A CA 2323574A CA 2323574 A1 CA2323574 A1 CA 2323574A1
Authority
CA
Canada
Prior art keywords
nucleic acid
protein
seq
sequence
acid molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002323574A
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English (en)
Inventor
Yatindra Prashar
Wufang Fan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ore Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2323574A1 publication Critical patent/CA2323574A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un nouveau gène régulé positivement dans un tissu cardiaque ischémique. L'invention concerne également des molécules d'acide nucléique renfermant le nouveau gène. Ces molécules d'acide nucléique peuvent être liées de façon fonctionnelle à un ou plusieurs éléments de régulation d'expression pour produire, par exemple, un vecteur de transformation de cellules hôtes. En mettant en culture ces cellules hôtes dans des conditions appropriées, la protéine du nouveau gène peut être exprimée et purifiée.
CA002323574A 1998-03-26 1999-03-26 Identification d'un adnc associe a l'ischemie dans un tissu cardiaque humain Abandoned CA2323574A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7937798P 1998-03-26 1998-03-26
US60/079,377 1998-03-26
PCT/US1999/006662 WO1999049062A1 (fr) 1998-03-26 1999-03-26 IDENTIFICATION D'UN ADNc ASSOCIE A L'ISCHEMIE DANS UN TISSU CARDIAQUE HUMAIN

Publications (1)

Publication Number Publication Date
CA2323574A1 true CA2323574A1 (fr) 1999-09-30

Family

ID=22150166

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002323574A Abandoned CA2323574A1 (fr) 1998-03-26 1999-03-26 Identification d'un adnc associe a l'ischemie dans un tissu cardiaque humain

Country Status (4)

Country Link
EP (1) EP1073756A4 (fr)
AU (1) AU3208999A (fr)
CA (1) CA2323574A1 (fr)
WO (1) WO1999049062A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2383244A1 (fr) * 1999-05-28 2000-12-07 Sugen, Inc. Proteines kinases
CA2398430A1 (fr) * 2000-01-25 2001-08-02 Sugen, Inc. Nouvelles proteines kinases humaines et enzymes semblables aux proteines kinases
US20040072170A1 (en) * 2000-05-30 2004-04-15 Bunk Daniela Beck Nee Novel target genes for diseases of the heart
US9580515B2 (en) * 2006-08-21 2017-02-28 Zensun (Shanghai) Science & Technology, Co., Ltd. Neukinase, a downstream protein of neuregulin
JP2009242388A (ja) * 2008-03-14 2009-10-22 National Cardiovascular Center 心臓特異的キナーゼの心不全診断および治療への応用
WO2013053076A1 (fr) 2011-10-10 2013-04-18 Zensun （Shanghai）Science & Technology Limited Compositions et procédés pour le traitement de l'insuffisance cardiaque

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174993B1 (en) * 1997-05-21 2001-01-16 The Children's Medical Center Corp. Short peptides which selectively modulate the activity of serine/threonine kinases
WO2002024889A2 (fr) * 2000-09-12 2002-03-28 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Contraction cardiaque optimisee par la phosphorylation differentielle de la myosine

Also Published As

Publication number Publication date
EP1073756A4 (fr) 2003-01-22
EP1073756A1 (fr) 2001-02-07
WO1999049062A1 (fr) 1999-09-30
AU3208999A (en) 1999-10-18

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Legal Events

Date Code Title Description
FZDE Discontinued