CA2322271C - Turbulence mixing head for a tissue sealant applicator and spray head for same - Google Patents
Turbulence mixing head for a tissue sealant applicator and spray head for same Download PDFInfo
- Publication number
- CA2322271C CA2322271C CA002322271A CA2322271A CA2322271C CA 2322271 C CA2322271 C CA 2322271C CA 002322271 A CA002322271 A CA 002322271A CA 2322271 A CA2322271 A CA 2322271A CA 2322271 C CA2322271 C CA 2322271C
- Authority
- CA
- Canada
- Prior art keywords
- sealant
- mixing
- applicator
- fluid
- components
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000565 sealant Substances 0.000 title claims abstract description 154
- 239000007921 spray Substances 0.000 title abstract description 54
- 239000012530 fluid Substances 0.000 claims abstract description 98
- 239000007787 solid Substances 0.000 claims description 24
- 230000008859 change Effects 0.000 claims description 8
- 230000007246 mechanism Effects 0.000 claims description 8
- 238000007789 sealing Methods 0.000 claims description 8
- 239000011343 solid material Substances 0.000 claims description 3
- 238000004891 communication Methods 0.000 claims description 2
- 229960004072 thrombin Drugs 0.000 abstract description 5
- 108090000190 Thrombin Proteins 0.000 abstract description 4
- 230000009977 dual effect Effects 0.000 abstract description 4
- 108010073385 Fibrin Proteins 0.000 abstract description 3
- 102000009123 Fibrin Human genes 0.000 abstract description 3
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 abstract description 3
- 229950003499 fibrin Drugs 0.000 abstract description 3
- 239000003106 tissue adhesive Substances 0.000 abstract description 3
- 239000007788 liquid Substances 0.000 description 57
- 210000001519 tissue Anatomy 0.000 description 26
- 239000000853 adhesive Substances 0.000 description 17
- 230000001070 adhesive effect Effects 0.000 description 17
- 239000000463 material Substances 0.000 description 14
- 239000000203 mixture Substances 0.000 description 13
- 210000003734 kidney Anatomy 0.000 description 12
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 description 9
- 230000037361 pathway Effects 0.000 description 9
- 238000012360 testing method Methods 0.000 description 9
- 241000283973 Oryctolagus cuniculus Species 0.000 description 8
- 210000003811 finger Anatomy 0.000 description 8
- 230000023597 hemostasis Effects 0.000 description 8
- 241001631457 Cannula Species 0.000 description 7
- 230000000740 bleeding effect Effects 0.000 description 7
- 210000000952 spleen Anatomy 0.000 description 7
- 210000003813 thumb Anatomy 0.000 description 7
- 238000010276 construction Methods 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 210000005224 forefinger Anatomy 0.000 description 5
- 230000006835 compression Effects 0.000 description 4
- 238000007906 compression Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- -1 polytetrafluoroethylene Polymers 0.000 description 4
- 230000001427 coherent effect Effects 0.000 description 3
- 239000003086 colorant Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000013011 mating Effects 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 108010049003 Fibrinogen Proteins 0.000 description 2
- 102000008946 Fibrinogen Human genes 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 230000001464 adherent effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 229940012952 fibrinogen Drugs 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 239000002874 hemostatic agent Substances 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 229920002379 silicone rubber Polymers 0.000 description 2
- 239000004945 silicone rubber Substances 0.000 description 2
- 210000003625 skull Anatomy 0.000 description 2
- 230000007480 spreading Effects 0.000 description 2
- 238000003892 spreading Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000000881 depressing effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229920006335 epoxy glue Polymers 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000011872 intimate mixture Substances 0.000 description 1
- 238000002406 microsurgery Methods 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 239000012778 molding material Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000010137 moulding (plastic) Methods 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229920000260 silastic Polymers 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000013517 stratification Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229940075469 tissue adhesives Drugs 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00503—Details of the outlet element
- B05C17/00516—Shape or geometry of the outlet orifice or the outlet element
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/02—Spray pistols; Apparatus for discharge
- B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
- B05B7/0408—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing two or more liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00553—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes with means allowing the stock of material to consist of at least two different components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00115—Electrical control of surgical instruments with audible or visual output
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Geometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgical Instruments (AREA)
- Nozzles (AREA)
- Coating Apparatus (AREA)
- Materials For Medical Uses (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7715698P | 1998-03-06 | 1998-03-06 | |
| US60/077,156 | 1998-03-06 | ||
| US09/037,160 US6063055A (en) | 1997-04-14 | 1998-03-09 | Turbulence mixing head for a tissue sealant applicator and spray head for same |
| US60/037,160 | 1998-03-09 | ||
| PCT/US1999/004830 WO1999044672A1 (en) | 1998-03-06 | 1999-03-05 | Turbulence mixing head for a tissue sealant applicator and spray head for same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2322271A1 CA2322271A1 (en) | 1999-09-10 |
| CA2322271C true CA2322271C (en) | 2009-07-07 |
Family
ID=26713859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002322271A Expired - Fee Related CA2322271C (en) | 1998-03-06 | 1999-03-05 | Turbulence mixing head for a tissue sealant applicator and spray head for same |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1059957B1 (https=) |
| JP (1) | JP2002505169A (https=) |
| AT (1) | ATE371472T1 (https=) |
| AU (1) | AU745108B2 (https=) |
| CA (1) | CA2322271C (https=) |
| DE (1) | DE69936982T2 (https=) |
| DK (1) | DK1059957T3 (https=) |
| ES (1) | ES2293719T3 (https=) |
| WO (1) | WO1999044672A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6585696B2 (en) | 2000-12-22 | 2003-07-01 | Baxter International, Inc. | Method and apparatus for applying a medically useful multiple component material |
| US7923431B2 (en) | 2001-12-21 | 2011-04-12 | Ferrosan Medical Devices A/S | Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis |
| CN1739017B (zh) | 2002-12-11 | 2011-04-06 | 弗罗桑医疗设备公司 | 用作拭子的基于明胶的材料 |
| WO2005072700A2 (en) | 2004-01-30 | 2005-08-11 | Ferrosan A/S | Haemostatic sprays and compositions |
| AU2005262070B2 (en) | 2004-07-09 | 2011-01-27 | Ferrosan Medical Devices A/S | Haemostatic composition comprising hyaluronic acid |
| DE102006006904A1 (de) * | 2006-02-09 | 2007-08-23 | Universität Rostock | Neue Mittel zur Blutstillung und Klebstoffe für medizinische Anwendungen |
| CN102014973A (zh) | 2008-02-29 | 2011-04-13 | 弗罗桑医疗设备公司 | 用于促进止血和/或伤口愈合的装置 |
| JP2011527607A (ja) * | 2008-07-08 | 2011-11-04 | ハイパーブランチ メディカル テクノロジー， インコーポレイテッド | 多成分処方のための独立式医療用アプリケータおよびその使用方法 |
| RU2657955C2 (ru) | 2012-03-06 | 2018-06-18 | Ферросан Медикал Дивайсиз А/С | Контейнер под давлением, содержащий гемостатическую пасту |
| EP2977066A3 (en) | 2012-06-12 | 2016-07-27 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
| AU2014283170B2 (en) | 2013-06-21 | 2017-11-02 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
| JP6489485B2 (ja) | 2013-12-11 | 2019-03-27 | フェロサン メディカル デバイシーズ エイ／エス | 押し出し増強因子を含んでいる乾燥組成物 |
| AU2015333206B2 (en) | 2014-10-13 | 2019-07-11 | Ferrosan Medical Devices A/S. | Dry composition for use in haemostasis and wound healing |
| RU2705905C2 (ru) | 2014-12-24 | 2019-11-12 | Ферросан Медикал Дивайсиз А/С | Шприц для удерживания и смешивания первого и второго веществ |
| CN107771093B (zh) | 2015-07-03 | 2021-06-15 | 弗罗桑医疗设备公司 | 用于混合两种组分和用于在存储条件下保持真空的注射器 |
| JP7002127B2 (ja) * | 2018-03-03 | 2022-01-20 | 武蔵エンジニアリング株式会社 | ピックアップ部材を備える吐出ヘッドおよび液体材料吐出装置 |
| EP3560427A1 (en) * | 2018-04-24 | 2019-10-30 | Gecko Biomedical | Applicator for depositing a layer of adhesive or sealant composition on a biological and/or prosthetic tissue |
| US11801324B2 (en) | 2018-05-09 | 2023-10-31 | Ferrosan Medical Devices A/S | Method for preparing a haemostatic composition |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3556348A (en) * | 1968-05-20 | 1971-01-19 | Robert J Bristow | Fluid mixing and dispensing apparatus |
| US4067479A (en) * | 1975-07-31 | 1978-01-10 | Products Research & Chemical Corporation | Two part material meter-mix dispenser apparatus |
| US4040420A (en) * | 1976-04-22 | 1977-08-09 | General Dynamics | Packaging and dispensing kit |
| US4083474A (en) * | 1977-03-21 | 1978-04-11 | Weyerhaeuser Company | Applicator gun for multi-component resin systems |
| US4471887A (en) * | 1982-04-26 | 1984-09-18 | Component Management Corp. | Dispensing device |
| US4978336A (en) | 1987-09-29 | 1990-12-18 | Hemaedics, Inc. | Biological syringe system |
| US5226877A (en) | 1989-06-23 | 1993-07-13 | Epstein Gordon H | Method and apparatus for preparing fibrinogen adhesive from whole blood |
| US5116315A (en) | 1989-10-03 | 1992-05-26 | Hemaedics, Inc. | Biological syringe system |
| PT689874E (pt) | 1994-06-28 | 2002-03-28 | Aventis Behring Gmbh | Dispositivo para a pulverizacao de uma mistura de dois componentes |
| WO1996039212A2 (en) * | 1995-06-06 | 1996-12-12 | Quantic Biomedical Partners | Wound sealant preparation and application device and method |
| JP3024765U (ja) * | 1995-11-17 | 1996-05-31 | 株式会社八光電機製作所 | 二薬液混合噴霧ノズル |
-
1999
- 1999-03-05 AT AT99911133T patent/ATE371472T1/de active
- 1999-03-05 ES ES99911133T patent/ES2293719T3/es not_active Expired - Lifetime
- 1999-03-05 AU AU29847/99A patent/AU745108B2/en not_active Ceased
- 1999-03-05 WO PCT/US1999/004830 patent/WO1999044672A1/en not_active Ceased
- 1999-03-05 JP JP2000534269A patent/JP2002505169A/ja active Pending
- 1999-03-05 CA CA002322271A patent/CA2322271C/en not_active Expired - Fee Related
- 1999-03-05 DK DK99911133T patent/DK1059957T3/da active
- 1999-03-05 EP EP99911133A patent/EP1059957B1/en not_active Expired - Lifetime
- 1999-03-05 DE DE69936982T patent/DE69936982T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002505169A (ja) | 2002-02-19 |
| DK1059957T3 (da) | 2008-01-02 |
| EP1059957A4 (en) | 2004-07-21 |
| AU745108B2 (en) | 2002-03-14 |
| ATE371472T1 (de) | 2007-09-15 |
| EP1059957B1 (en) | 2007-08-29 |
| CA2322271A1 (en) | 1999-09-10 |
| EP1059957A1 (en) | 2000-12-20 |
| DE69936982T2 (de) | 2008-05-15 |
| ES2293719T3 (es) | 2008-03-16 |
| AU2984799A (en) | 1999-09-20 |
| WO1999044672A1 (en) | 1999-09-10 |
| DE69936982D1 (de) | 2007-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20170306 |