CA2320302A1 - Gene transfer-mediated angiogenesis therapy and techniques for intravascular gene delivery - Google Patents

Gene transfer-mediated angiogenesis therapy and techniques for intravascular gene delivery Download PDF

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Publication number
CA2320302A1
CA2320302A1 CA002320302A CA2320302A CA2320302A1 CA 2320302 A1 CA2320302 A1 CA 2320302A1 CA 002320302 A CA002320302 A CA 002320302A CA 2320302 A CA2320302 A CA 2320302A CA 2320302 A1 CA2320302 A1 CA 2320302A1
Authority
CA
Canada
Prior art keywords
vector
histamine
fgf
protein
transgene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002320302A
Other languages
English (en)
French (fr)
Inventor
H. Kirk Hammond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2320302A1 publication Critical patent/CA2320302A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0075Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0083Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the administration regime
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Paints Or Removers (AREA)
CA002320302A 1998-02-11 1999-02-09 Gene transfer-mediated angiogenesis therapy and techniques for intravascular gene delivery Abandoned CA2320302A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2177398A 1998-02-11 1998-02-11
US09/021,773 1998-02-11
PCT/US1999/002702 WO1999040945A2 (en) 1998-02-11 1999-02-09 Combination of a nucleic acid and a vasoactive agent for enhanced gene delivery

Publications (1)

Publication Number Publication Date
CA2320302A1 true CA2320302A1 (en) 1999-08-19

Family

ID=21806073

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002320302A Abandoned CA2320302A1 (en) 1998-02-11 1999-02-09 Gene transfer-mediated angiogenesis therapy and techniques for intravascular gene delivery

Country Status (11)

Country Link
EP (2) EP1695719A1 (https=)
JP (1) JP2002502885A (https=)
KR (1) KR20010015915A (https=)
CN (2) CN101186928A (https=)
AU (1) AU2663799A (https=)
CA (1) CA2320302A1 (https=)
EA (1) EA019099B1 (https=)
IL (1) IL137765A0 (https=)
NZ (1) NZ545047A (https=)
WO (1) WO1999040945A2 (https=)
ZA (1) ZA991102B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001034208A1 (en) * 1999-11-05 2001-05-17 The Regents Of The University Of California Techniques and compositions for treating cardiovascular disease by in vivo gene delivery
US6752987B1 (en) 1995-02-28 2004-06-22 The Regents Of The University Of California Adenovirus encoding human adenylylcyclase (AC) VI
WO2000024415A2 (en) 1998-10-28 2000-05-04 Cornell Research Foundation, Inc. Methods for regulating angiogenesis and vascular integrity using trk receptor ligands
EP1255822A2 (en) 1999-12-27 2002-11-13 The Regents Of The University Of California Modified adenylylcyclase type vi useful in gene therapy for congestive heart failure
WO2002002148A2 (en) * 2000-06-30 2002-01-10 Collateral Therapeutics, Inc. Dual recombinant gene therapy compositions and methods of use
JP2005052001A (ja) * 2001-07-05 2005-03-03 Takara Bio Inc 遺伝子治療剤
DE602006017071D1 (de) 2005-01-25 2010-11-04 Five Prime Therapeutics Inc Zusammensetzungen und verfahren zur behandlung von herzkrankheiten
GB2437893A (en) * 2006-07-25 2007-11-07 Celladon Corp Extended antegrade epicardial coronary infusion of adeno-associated viral vectors for gene therapy
US8157760B2 (en) 2007-07-18 2012-04-17 Silk Road Medical, Inc. Methods and systems for establishing retrograde carotid arterial blood flow
WO2009105135A1 (en) 2008-02-19 2009-08-27 Celladon Corporation Compositions for enhanced uptake of viral vectors in the myocardium
US20130096500A1 (en) * 2011-07-07 2013-04-18 Gabor Rubanyi Nucleic acid based cardiovascular therapeutics
US20140296769A1 (en) * 2013-03-28 2014-10-02 Silk Road Medical, Inc. Methods and Systems for Establishing Retrograde Carotid Arterial Blood Flow
WO2019089385A1 (en) 2017-11-02 2019-05-09 Silk Road Medical, Inc. Fenestrated sheath for embolic protection during transcarotid carotid artery revascularization

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA001616B1 (ru) * 1995-02-28 2001-06-25 Зе Риджентс Оф Зи Юнивесити Оф Кэлифоньэ Способ лечения болезни сердца, способ лечения недостаточности периферических сосудов и способ ограничения доставки и экспрессии трансгенной конструкции в определенном органе или структуре
US5869230A (en) * 1995-03-30 1999-02-09 Beth Israel Hospital Association Gene transfer into the kidney
WO1999017807A1 (en) * 1997-10-08 1999-04-15 Cobra Therapeutics Ltd. Use of a vasoactive compound in the enhancement of gene delivery
US6376471B1 (en) * 1997-10-10 2002-04-23 Johns Hopkins University Gene delivery compositions and methods

Also Published As

Publication number Publication date
CN1301181A (zh) 2001-06-27
ZA991102B (en) 2000-03-31
JP2002502885A (ja) 2002-01-29
EA200000828A1 (ru) 2001-02-26
WO1999040945A3 (en) 1999-09-30
AU2663799A (en) 1999-08-30
CN101186928A (zh) 2008-05-28
NZ545047A (en) 2009-05-31
EP1695719A1 (en) 2006-08-30
CN100350979C (zh) 2007-11-28
IL137765A0 (en) 2001-10-31
KR20010015915A (ko) 2001-02-26
EA019099B1 (ru) 2014-01-30
WO1999040945A2 (en) 1999-08-19
EP1053025A2 (en) 2000-11-22

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20160623